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Top results for amlodipine

21. Tolerability and effectiveness of (S)-amlodipine compared with racemic amlodipine in hypertension: a systematic review and meta-analysis

Tolerability and effectiveness of (S)-amlodipine compared with racemic amlodipine in hypertension: a systematic review and meta-analysis Tolerability and effectiveness of (S)-amlodipine compared with racemic amlodipine in hypertension: a systematic review and meta-analysis Tolerability and effectiveness of (S)-amlodipine compared with racemic amlodipine in hypertension: a systematic review and meta-analysis Liu F, Qiu M, Zhai SD CRD summary This review concluded that according to limited (...) evidence there were no significant differences between (S)-amlodipine 2.5mg and racemic amlodipine 5mg in blood pressure. (S)-amlodipine resulted in significantly less oedema, although not in higher quality studies. The review was well-conducted, but the results should be treated with caution due to the scarcity of high-quality studies. Authors' objectives To determine the effectiveness and tolerability of (S)-amlodipine compared with racemic amlodipine in hypertension. Searching MEDLINE (from 1966

DARE.2010

22. Amlodipine and angiotensin-converting enzyme inhibitor combination versus amlodipine monotherapy in hypertension: a meta-analysis of randomized controlled trials

Amlodipine and angiotensin-converting enzyme inhibitor combination versus amlodipine monotherapy in hypertension: a meta-analysis of randomized controlled trials Amlodipine and angiotensin-converting enzyme inhibitor combination versus amlodipine monotherapy in hypertension: a meta-analysis of randomized controlled trials Amlodipine and angiotensin-converting enzyme inhibitor combination versus amlodipine monotherapy in hypertension: a meta-analysis of randomized controlled trials Lv Y, Zou Z (...) , Chen GM, Jia HX, Zhong J, Fang WW CRD summary The authors concluded that combination treatment with amlodipine and ACEIs was more effective than amlodipine monotherapy in blood pressure control and had fewer adverse events in patients with hypertension. This was a well-conducted review. The authors' conclusion reflects the evidence presented, but reliability should be treated with caution due to the suboptimal quality of included studies. Authors' objectives To evaluate the efficacy

DARE.2010

23. Amlodipin + Atorvastatin

Amlodipin + Atorvastatin 2010. DAR No 2: Amlodipin + Atorvastatin - navarra.es Castellano | Euskara | Français | English Use the search tool! Search engine : : : : : : : : DAR No 2: Amlodipin + Atorvastatin DAR No 2: Amlodipin + Atorvastatin Content tools Share it A combination that makes no sense The combination of amlodipin-atorvastatin is indicated in the prevention of cardiovascular events in hypertensive patients with three other concomitant risk factors, and with normal or mildly elevated (...) cholesterol levels. The efficacy of statins to reduce cardiovascular risk in primary prevention in patients with normal cholesterol levels has not been sufficiently demonstrated. The addition of atorvastatin in patients under treatment with amlodipin in the indication mentioned increases the risk of adverse reactions and the cost of treatment with no clear health benefits. Therefore this combination is not justified. Enviar comentario You can send us a comment or suggestion and we will respond to most frequently

Drug and Therapeutics Bulletin of Navarre (Spain)2010

24. Twynsta - telmisartan / amlodipine

Twynsta - telmisartan / amlodipine 7 Westferry Circus ? Canary Wharf ? London E14 4HB ? United Kingdom Telephone +44 (0)20 7418 8400 Facsimile +44 (0)20 7523 7455 E-mail info@ema.europa.eu Website www.ema.europa.eu An agency of the European Union © European Medicines Agency, 2010. Reproduction is authorised provided the source is acknowledged. 22 July 2010 EMA/576613/2010 Committee for Medicinal Products for Human Use (CHMP) CHMP assessment report TWYNSTA International Nonproprietary Name (...) : telmisartan / amlodipine Procedure No. EMEA/H/C/001224 Assessment Report as adopted by the CHMP with all information of a commercially confidential nature deleted Table of contents Page 1. Background information on the procedure 3 1.1. Submission of the dossier 3 1.2. Steps taken for the assessment of the product 4 2. Scientific discussion 5 2.1. Introduction 5 2.2. Quality aspects 5 2.3. Non-clinical aspects 8 2.4. Clinical aspects 18 2.5. Clinical efficacy 27 2.6. Clinical safety 44 2.7

European Medicines Agency - EPARs2010

25. Tribenzor (olmesartan medoxomil / amlodipine / hydrochlorothiazide)

Tribenzor (olmesartan medoxomil / amlodipine / hydrochlorothiazide) Drug Approval Package: TRIBENZOR (olmesartan medoxomil and amlodipine) NDA #200175 Drug Approval Package U.S. Food & Drug Administration Enter Search terms Drug Approval Package - TRIBENZOR (olmesartan medoxomil / amlodipine / hydrochlorothiazide) Tablets Company: Daiichi Sankyo, Inc. Application No.: 200175 Approval Date: 07/23/2010 Persons with disabilities having problems accessing the PDF files below may call (301) 796-3634

FDA - Drug Approval Package2010

26. Tekamlo, (aliskiren/amlodipine)

Tekamlo, (aliskiren/amlodipine) Drug Approval Package: Tekamlo (aliskiren/amlodipine) NDA #022545 Drug Approval Package U.S. Food & Drug Administration Enter Search terms Drug Approval Package - Tekamlo, (aliskiren/amlodipine) 150 mg/5 mg, 150 mg/10 mg, 300 mg/5 mg and 300 mg/10 mg Tablets Company: Novartis Pharmaceuticals Corporation Application No.: 022545 Approval Date: 08/26/2010 Persons with disabilities having problems accessing the PDF files below may call (301) 796-3634 for assistance

FDA - Drug Approval Package2010

27. Amturnide (amlodipine/aliskiren/hydrochlorothiazide)

Amturnide (amlodipine/aliskiren/hydrochlorothiazide) Drug Approval Package: Amturnide(amlodipine/aliskiren/hydrochlorothiazide) NDA #200045 Drug Approval Package U.S. Food & Drug Administration Enter Search terms Drug Approval Package - Amturnide (amlodipine/aliskiren/hydrochlorothiazide) 150/5/12.5 mg, 300/5/12.5 mg, 300/5/25 mg, 300/10/12.5 mg and 300/10/25 mg Tablets Company: Novartis Pharmaceuticals Application No.: 200045 Approval Date: 12/21/2010 Persons with disabilities having problems

FDA - Drug Approval Package2010

29. The lifetime cost effectiveness of amlodipine-based therapy plus atorvastatin compared with atenolol plus atorvastatin, amlodipine-based therapy alone and atenolol-based therapy alone: results from ASCOT

The lifetime cost effectiveness of amlodipine-based therapy plus atorvastatin compared with atenolol plus atorvastatin, amlodipine-based therapy alone and atenolol-based therapy alone: results from ASCOT The lifetime cost effectiveness of amlodipine-based therapy plus atorvastatin compared with atenolol plus atorvastatin, amlodipine-based therapy alone and atenolol-based therapy alone: results from ASCOT The lifetime cost effectiveness of amlodipine-based therapy plus atorvastatin compared (...) with atenolol plus atorvastatin, amlodipine-based therapy alone and atenolol-based therapy alone: results from ASCOT Lindgren P, Buxton M, Kahan T, Poulter NR, Dahlof B, Sever PS, Wedel H, Jonsson B, Anglo-Scandinavian Cardiac Outcomes Trial investigators Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment

NHS Economic Evaluation Database.2009

30. Results of a Markov model analysis to assess the cost-effectiveness of a single tablet of fixed-dose amlodipine and atorvastatin for the primary prevention of cardiovascular disease in Korea

Results of a Markov model analysis to assess the cost-effectiveness of a single tablet of fixed-dose amlodipine and atorvastatin for the primary prevention of cardiovascular disease in Korea Results of a Markov model analysis to assess the cost-effectiveness of a single tablet of fixed-dose amlodipine and atorvastatin for the primary prevention of cardiovascular disease in Korea Results of a Markov model analysis to assess the cost-effectiveness of a single tablet of fixed-dose amlodipine (...) and atorvastatin for the primary prevention of cardiovascular disease in Korea Liew D, Park HJ, Ko SK Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary This study examined the cost-effectiveness of a single-tablet fixed-dose combination of amlodipine

NHS Economic Evaluation Database.2009

31. Copalia HCT - amlodipine / valsartan / hydrochlorothiazide

Copalia HCT - amlodipine / valsartan / hydrochlorothiazide European Medicines Agency Evaluation of Medicines for Human Use 7 Westferry Circus, Canary Wharf, London, E14 4HB, UK Tel. (44-20) 74 18 84 00 Fax (44-20) 75 23 70 51 E-mail: mail@emea.europa.eu http://www.emea.europa.eu Doc.Ref: EMEA/CHMP/471143/2009 ASSESSMENT REPORT FOR Copalia HCT International Nonproprietary Name: amlodipine besylate / valsartan / hydrochlorothiazide Procedure No. EMEA/H/C/001159 Assessment Report as adopted (...) new fixed combination products. The applicant applied for the following indication: “Treatment of essential hypertension. Copalia HCT is indicated as replacement therapy in patients whose blood pressure is adequately controlled on amlodipine, valsartan and hydrochlorothiazide (HCT) used as individual or combination therapies”. Information on Paediatric requirements Pursuant to Article 7, the application included an EMEA Decision P/14/2009 for the following condition: • Essential hypertension on

European Medicines Agency - EPARs2009

32. Twynsta (telmisartan/amlodipine)

Twynsta (telmisartan/amlodipine) Drug Approval Package: Twynsta (telmisartan/amlodipine) NDA #022401 Drug Approval Package U.S. Food & Drug Administration Enter Search terms Drug Approval Package - Twynsta (telmisartan/amlodipine) 40/5, 40/10, 80/5, 80/10 mg Tablets Company: Boehringer Ingelheim Pharmaceuticals, Inc. Application No.: 022401 Approval Date: 10/16/2009 Persons with disabilities having problems accessing the PDF files below may call (301) 796-3634 for assistance. (PDF) (PDF) (PDF

FDA - Drug Approval Package2009

33. Economic evaluation of ASCOT-BPLA: antihypertensive treatment with an amlodipine-based regimen is cost effective compared with an atenolol-based regimen

Economic evaluation of ASCOT-BPLA: antihypertensive treatment with an amlodipine-based regimen is cost effective compared with an atenolol-based regimen 17916665 2008 01 15 2008 01 30 2013 11 21 1468-201X 94 2 2008 Feb Heart (British Cardiac Society) Heart Economic evaluation of ASCOT-BPLA: antihypertensive treatment with an amlodipine-based regimen is cost effective compared with an atenolol-based regimen. e4 To compare the cost effectiveness of an amlodipine-based strategy and an atenolol (...) -based strategy in the treatment of hypertension in the UK and Sweden. A prospective, randomised trial complemented with a Markov model to assess long-term costs and health effects. Primary care. Patients with moderate hypertension and three or more additional risk factors. Amlodipine 5-10 mg with perindopril 4-8 mg added as needed or atenolol 50-100 mg with bendroflumethiazide 1.25-2.5 mg and potassium added as needed Cost per cardiovascular event and procedure avoided, and cost per quality-adjusted

EvidenceUpdates2008

34. An Asian regional analysis of cost-effectiveness of early irbesartan treatment versus conventional antihypertensive, late amlodipine, and late irbesartan treatments in patients with type 2 diabetes, hypertension, and nephropathy

An Asian regional analysis of cost-effectiveness of early irbesartan treatment versus conventional antihypertensive, late amlodipine, and late irbesartan treatments in patients with type 2 diabetes, hypertension, and nephropathy An Asian regional analysis of cost-effectiveness of early irbesartan treatment versus conventional antihypertensive, late amlodipine, and late irbesartan treatments in patients with type 2 diabetes, hypertension, and nephropathy An Asian regional analysis of cost (...) -effectiveness of early irbesartan treatment versus conventional antihypertensive, late amlodipine, and late irbesartan treatments in patients with type 2 diabetes, hypertension, and nephropathy Annemans L, Demarteau N, Hu S, Lee T J, Morad Z, Supaporn T, Yang W C, Palmer A J Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical

NHS Economic Evaluation Database.2008

35. Economic evaluation of ASCOT-BPLA: antihypertensive treatment with an amlodipine-based regimen is cost effective compared with an atenolol-based regimen

Economic evaluation of ASCOT-BPLA: antihypertensive treatment with an amlodipine-based regimen is cost effective compared with an atenolol-based regimen Economic evaluation of ASCOT-BPLA: antihypertensive treatment with an amlodipine-based regimen is cost effective compared with an atenolol-based regimen Economic evaluation of ASCOT-BPLA: antihypertensive treatment with an amlodipine-based regimen is cost effective compared with an atenolol-based regimen Lindgren P, Buxton M, Kahan T, Poulter N (...) R, Dahlof B, Sever P S, Wedel H, Jonsson B Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary The objective was to compare the cost-effectiveness of an amlodipine-based strategy and an atenolol-based strategy in the treatment

NHS Economic Evaluation Database.2008

36. Benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients.

Benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients. 19052124 2008 12 04 2008 12 09 2014 07 31 1533-4406 359 23 2008 Dec 04 The New England journal of medicine N. Engl. J. Med. Benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients. 2417-28 10.1056/NEJMoa0806182 The optimal combination drug therapy for hypertension is not established, although current U.S. guidelines recommend inclusion of a diuretic. We hypothesized (...) that treatment with the combination of an angiotensin-converting-enzyme (ACE) inhibitor and a dihydropyridine calcium-channel blocker would be more effective in reducing the rate of cardiovascular events than treatment with an ACE inhibitor plus a thiazide diuretic. In a randomized, double-blind trial, we assigned 11,506 patients with hypertension who were at high risk for cardiovascular events to receive treatment with either benazepril plus amlodipine or benazepril plus hydrochlorothiazide. The primary end

NEJM2008

37. Amlodipine plus perindopril was better than atenolol plus bendroflumethiazide for reducing complications in hypertension

Amlodipine plus perindopril was better than atenolol plus bendroflumethiazide for reducing complications in hypertension Amlodipine plus perindopril was better than atenolol plus bendroflumethiazide for reducing complications in hypertension | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user (...) name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Amlodipine plus perindopril was better than atenolol plus bendroflumethiazide for reducing complications in hypertension Article Text Therapeutics Amlodipine plus perindopril was better than atenolol plus bendroflumethiazide for reducing complications

Evidence-Based Medicine (Requires free registration)2007

38. Irbesartan and amlodipine in the treatment of patients with microalbuminuria, hypertension and type 2 diabetes in Taiwan: a modelling projection over 25 years

Irbesartan and amlodipine in the treatment of patients with microalbuminuria, hypertension and type 2 diabetes in Taiwan: a modelling projection over 25 years Irbesartan and amlodipine in the treatment of patients with microalbuminuria, hypertension and type 2 diabetes in Taiwan: a modelling projection over 25 years Irbesartan and amlodipine in the treatment of patients with microalbuminuria, hypertension and type 2 diabetes in Taiwan: a modelling projection over 25 years Yang W C, Hwang S J (...) , Annemans L, Ray J A, Roze S, Valentine W J, Palmer A J Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary The objective was to evaluate the long-term cost-effectiveness of early irbesartan, late irbesartan, amlodipine, and standard

NHS Economic Evaluation Database.2007

40. Copalia - amlodipine / valsartan

Copalia - amlodipine / valsartan ©EMEA 2007 1/2929291 SCIENTIFIC DISCUSSION 1. Introduction The proper management and control of blood pressure in hypertension patients, and the impact it has on associated morbidity and mortality rates, has been the focus of many new hypertension observational studies and clinical trials. These trials have demonstrated that more aggressive blood pressure lowering will reduce the complications associated with hypertension. As a result of this data, international (...) . Therefore, the applicant was asked for a commitment to perform a separate study in elderly patients (see: follow-up measures). • Adverse events A literature search for the combination therapy did not provide any unknown AE or AES. Adverse events by primary system organ class generally show comparable incidences between the valsartan/amlodipine group, the monotherapy groups and the placebo groups. The most frequently occurring AE in the total valsartan/amlodipine group was peripheral edema. It occurred

European Medicines Agency - EPARs2007