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Molecular Diagnostics for AIDS Lymphoma Diagnosis in South Africa and the Potential for Other Low- and Middle-Income Countries 30241211 2019 03 04 2378-9506 4 2018 Sep Journal of global oncology J Glob Oncol Molecular Diagnostics for AIDS Lymphoma Diagnosis in South Africa and the Potential for Other Low- and Middle-Income Countries. 1-6 10.1200/JGO.17.00043 Vogt Samantha L SL Samantha L. Vogt and Richard Ambinder, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD; Moosa (...) Mar;2(1):42-9 8287225 N Engl J Med. 1983 Dec 29;309(26):1593-9 6417538 Oncotarget. 2017 Jan 31;8(5):8765-8774 28060738 Lancet Infect Dis. 2013 Apr;13(4):349-61 23531388 PLoS One. 2012;7(10):e47542 23094059 Blood. 2010 Apr 15;115(15):3017-24 20130244 J Clin Oncol. 2006 Sep 1;24(25):4123-8 16896005 Lancet Oncol. 2015 May;16(5):541-9 25842160 J Acquir Immune Defic Syndr. 2011 Mar 1;56(3):292-5 21317587 AIDS Res Ther. 2017 Mar 14;14(1):13 28292305 Lancet Infect Dis. 2014 Jun;14(6):527-32 24438820 Int
Patient Decision Aids to Engage Adults in Treatment or Screening Decisions. Are patient decision aids (PtDAs) associated with (1) improved decision quality defined as a decision informed by the evidence and a value-based decision; (2) improved decision-making processes defined as feeling informed, defining clear values related to the decision, and active participation in making the decision; and (3) better patient and health system outcomes compared with either usual care or a non-PtDA (...) intervention?Patient decision aids are associated with improved decision quality and decision-making processes without worse patient or health system outcomes.
Does foreign aid crowd out government investments? Evidence from rural health centres in Rwanda Rural healthcare facilities in low-income countries play a major role in providing primary care to rural populations. We examined the link of foreign aid with government investments and medical service provision in rural health centres in Rwanda.Using the District Health System Strengthening Tool, a web-based database built by the Ministry of Health in Rwanda, we constructed two composite indices (...) representing provision of (1) child and maternal care and (2) HIV, tuberculosis (TB) and malaria services in 330 rural health centres between 2009 and 2011. Financing variables in a healthcare centre included received funds from various sources, including foreign donors and government. We used multilevel random-effects model in regression analyses and examined the robustness of results to a range of alternative specification, including scale of dependent variables, estimation methods and timing of aid
Exploring the perception of aid organizationsâ€™ staff about factors affecting management of mass casualty traffic incidents in Iran: a grounded theory study Traffic incidents are of main health issues all around the world and cause countless deaths, heavy casualties, and considerable tangible and intangible damage. In this regard, mass casualty traffic incidents are worthy of special attention as, in addition to all losses and damage, they create challenges in the way of providing health (...) services to the victims.The present study is an attempt to explore the challenges and facilitators in management of mass casualty traffic incidents in Iran.This qualitative grounded theory study was carried out with participation of 14 purposively selected experienced managers, paramedics and staff of aid organizations in different provinces of Iran in 2016. Semi-structured interviews were conducted in order to develop the theory. The transcribed interviews were analyzed through open, axial
Personal Sound Amplification Products vs a Conventional Hearing Aid for Speech Understanding in Noise 28672306 2017 08 22 2018 11 13 1538-3598 318 1 2017 07 04 JAMA JAMA Personal Sound Amplification Products vs a Conventional Hearing Aid for Speech Understanding in Noise. 89-90 10.1001/jama.2017.6905 Reed Nicholas S NS Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland. Betz Joshua J Department of Biostatistics, Johns Hopkins Bloomberg (...) States Comparative Study Journal Article Randomized Controlled Trial Research Support, N.I.H., Extramural United States JAMA 7501160 0098-7484 AIM IM JAMA. 2017 Nov 14;318(18):1831 29136438 Aged Aged, 80 and over Equipment Design Female Hearing Aids Hearing Loss rehabilitation Humans Male Middle Aged Speech Perception 2017 7 4 6 0 2017 7 4 6 0 2017 8 23 6 0 ppublish 28672306 2635618 10.1001/jama.2017.6905 PMC5817472 Ear Hear. 2012 Jan-Feb;33(1):112-7 21829134 Arch Intern Med. 2012 Feb 13;172(3):292-3
Clinical Calculator for Early Mortality in Metastatic Colorectal Cancer: An Analysis of Patients From 28 Clinical Trials in the Aide et Recherche en Cancerologie Digestive Database Purpose Factors contributing to early mortality after initiation of treatment of metastatic colorectal cancer are poorly understood. Materials and Methods Data from 22,654 patients enrolled in 28 randomized phase III trials contained in the ARCAD (Aide et Recherche en Cancérologie Digestive) database were pooled
Addressing varenicline adherence through repackaging in a dose administration aid Ensuring adherence to prescribed smoking cessation medications, such as Champix® (varenicline), is essential during a quit attempt as non-adherence can significantly reduce the likelihood of achieving prolonged smoking abstinence. The use of dose administration aids may improve adherence, though medication stability on repackaging is not guaranteed, due to a lack of available data from manufacturers supporting (...) this practice.To determine the suitability for repackaging varenicline tartrate tablets into a dose administration aid, by assessing its physical and chemical stability after being repackaged and stored at ambient conditions for 6 weeks.Varenicline tartrate (1.0 mg) tablets were repackaged into commercially available Webster-pak® blister compartments and stored for 42 days at ambient conditions characteristic of a Zone IVB climate (30 ± 2°C and 75 ± 5% relative humidity) according to the World Health
Effectiveness of self-administered decision aids for people invited to participate in colorectal cancer screening: a systematic review protocol. The objective is to assess the effectiveness of self-administered decision aids for people invited to participate in colorectal cancer screening. We will evaluate effects on informed choice, decisional conflict, knowledge, and participation in colorectal cancer screening.
Computer-Aided Systematic Review Screening Comes of Age. 28605802 2017 12 11 2018 12 02 1539-3704 167 3 2017 08 01 Annals of internal medicine Ann. Intern. Med. Computer-Aided Systematic Review Screening Comes of Age. 210-211 10.7326/M17-1295 Hemens Brian J BJ From McMaster University, Hamilton, Ontario, Canada. Iorio Alfonso A From McMaster University, Hamilton, Ontario, Canada. eng Journal Article Comment 2017 06 13 United States Ann Intern Med 0372351 0003-4819 AIM IM Ann Intern Med. 2017
The Use of Transdermal Buprenorphine Patches in Aiding in Opioid Withdrawal: Clinical Effectiveness and Guidelines The Use of Transdermal Buprenorphine Patches in Aiding in Opioid Withdrawal: Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need The Use of Transdermal Buprenorphine Patches in Aiding in Opioid Withdrawal: Clinical Effectiveness and Guidelines The Use of Transdermal Buprenorphine Patches in Aiding in Opioid Withdrawal: Clinical Effectiveness (...) and Guidelines Published on: June 8, 2017 Project Number: RA0911-000 Product Line: Research Type: Drug Report Type: Reference List Result type: Report Question What is the clinical effectiveness regarding the use of buprenorphine patches for aiding in opioid withdrawal prior to starting a patient on buprenorphine/naloxone? What are the evidence-based guidelines regarding the use of buprenorphine patches for aiding in opioid withdrawal prior to starting a patient on buprenorphine/naloxone? Key Message One non
Effect of Combined Patient Decision Aid and Patient Navigation vs Usual Care for Colorectal Cancer Screening in a Vulnerable Patient Population: A Randomized Clinical Trial Colorectal cancer (CRC) screening is underused, especially among vulnerable populations. Decision aids and patient navigation are potentially complementary interventions for improving CRC screening rates, but their combined effect on screening completion is unknown.To determine the combined effect of a CRC screening decision (...) aid and patient navigation compared with usual care on CRC screening completion.In this randomized clinical trial, data were collected from January 2014 to March 2016 at 2 community health center practices, 1 in North Carolina and 1 in New Mexico, serving vulnerable populations. Patients ages 50 to 75 years who had average CRC risk, spoke English or Spanish, were not current with recommended CRC screening, and were attending primary care visits were recruited and randomized 1:1 to intervention
Decision aids for people facing health treatment or screening decisions. Decision aids are interventions that support patients by making their decisions explicit, providing information about options and associated benefits/harms, and helping clarify congruence between decisions and personal values.To assess the effects of decision aids in people facing treatment or screening decisions.Updated search (2012 to April 2015) in CENTRAL; MEDLINE; Embase; PsycINFO; and grey literature; includes CINAHL (...) to September 2008.We included published randomized controlled trials comparing decision aids to usual care and/or alternative interventions. For this update, we excluded studies comparing detailed versus simple decision aids.Two reviewers independently screened citations for inclusion, extracted data, and assessed risk of bias. Primary outcomes, based on the International Patient Decision Aid Standards (IPDAS), were attributes related to the choice made and the decision-making process.Secondary outcomes
Aid effectiveness and programmatic effectiveness: a proposed framework for comparative evaluation of different aid interventions in a particular health system Against a backdrop of changing concepts of aid effectiveness, development effectiveness, health systems strengthening, and increasing emphasis on impact evaluation, this article proposes a theory-driven impact evaluation framework to gauge the effect of aid effectiveness principles on programmatic outcomes of different aid funded programs (...) in the health sector of a particular country.The foundation and step-by-step process of implementing the framework are described.With empirical evidence from the field, the steps involve analysis of context, program designs, implementation mechanisms, outcomes, synthesis, and interpretation of findings through the programs' underlying program theories and interactions with the state context and health system.The framework can be useful for comparatively evaluating different aid interventions both in fragile
UNAIDS 90â€“90â€“90 targets to end the AIDS epidemic by 2020 are not realistic: comment on â€œCan the UNAIDS 90â€“90â€“90 target be achieved? A systematic analysis of national HIV treatment cascadesâ€ 28589026 2018 11 13 2059-7908 2 2 2017 BMJ global health BMJ Glob Health UNAIDS 90-90-90 targets to end the AIDS epidemic by 2020 are not realistic: comment on "Can the UNAIDS 90-90-90 target be achieved? A systematic analysis of national HIV treatment cascades". e000227 10.1136/bmjgh-2016-000227 (...) 101685275 2059-7908 Competing interests: None declared. 2016 10 29 2017 01 03 2017 01 06 2017 6 8 6 0 2017 6 8 6 0 2017 6 8 6 1 epublish 28589026 10.1136/bmjgh-2016-000227 bmjgh-2016-000227 PMC5435269 BMC Public Health. 2016 Sep 21;16(1):1002 27655406 PLoS One. 2016 Jun 07;11(6):e0156619 27272890 Lancet. 2014 Jul 19;384(9939):258-71 24907868 AIDS Care. 2017 Mar;29(3):326-334 27539782 J Int AIDS Soc. 2015 Jul 23;18:20090 26208630 Trop Med Int Health. 2016 Feb;21(2):219-23 26584666 J Med Ethics. 2014 Jul
Foundation and methodologies in computer-aided diagnosis systems for breast cancer detection Breast cancer is the most prevalent cancer that affects women all over the world. Early detection and treatment of breast cancer could decline the mortality rate. Some issues such as technical reasons, which related to imaging quality and human error, increase misdiagnosis of breast cancer by radiologists. Computer-aided detection systems (CADs) are developed to overcome these restrictions and have been
Strategies for improving the lives of women aged 40 and above living with HIV/AIDS. Strategies for improving the lives of women aged 40 and above living with HIV/AIDS. Strategies for improving the lives of women aged 40 and above living with HIV/AIDS. Adam GP, Di M, Cu-Uvin S, Halladay C, Smith BT, Trikalinos TA Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made (...) for the HTA database. Citation Adam GP, Di M, Cu-Uvin S, Halladay C, Smith BT, Trikalinos TA. Strategies for improving the lives of women aged 40 and above living with HIV/AIDS. Rockville: Agency for Healthcare Research and Quality (AHRQ). Technical Brief No. 29. 2016 Authors' objectives While in its early years the HIV epidemic affected primarily the male and the young, nowadays the population living with HIV/AIDS comprises approximately 24 percent women, and its age composition has shifted towards older
Dental Students Can Benefit by Starting to Learn Indirect Vision (Mirror) Skills Early in Preclinical Studies with The Aid of a Training Device UTCAT3133, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Dental Students Can Benefit by Starting to Learn Indirect Vision (Mirror) Skills Early in Preclinical Studies with The Aid of a Training Device Clinical Question In dental students, does use of a training device lead
Assessing and Refining Myocardial Infarction Risk Estimation among Patients with Human Immunodeficiency Virus: Centers for AIDS Research Network of Integrated Clinical Systems (CNICS) Persons with human immunodeficiency virus (HIV) that is treated with antiretroviral therapy have improved longevity but face an elevated risk of myocardial infarction (MI) due to common MI risk factors and HIV-specific factors. Despite these elevated MI rates, optimal methods to predict MI risks for HIV-infected (...) persons remain unclear.To determine the extent to which existing and de novo estimation tools predict MI in a multicenter HIV cohort with rigorous MI adjudication.We evaluated the performance of standard of care and 2 new data-derived MI risk estimation models in 5 Centers for AIDS Research Network of Integrated Clinical Systems sites across the United States where a multicenter clinical prospective cohort of 19 829 HIV-infected adults received care in inpatient and outpatient settings since 1995
Who pays for cooperation in global health? A comparative analysis of WHO, the World Bank, the Global Fund to Fight HIV/AIDS, Tuberculosis and Malaria, and Gavi, the Vaccine Alliance. In this report we assess who pays for cooperation in global health through an analysis of the financial flows of WHO, the World Bank, the Global Fund to Fight HIV/AIDS, TB and Malaria, and Gavi, the Vaccine Alliance. The past few decades have seen the consolidation of influence in the disproportionate roles the USA
Taking the health aid debate to the subnational level: the impact and allocation of foreign health aid in Malawi Cross-national studies provide inconclusive results as to the effectiveness of foreign health aid. We highlight a novel application of using subnational data to evaluate aid impacts, using Malawi as a case study.We employ two rounds of nationally representative household surveys (2004/2005 and 2010/2011) and geo-referenced foreign aid data. We examine the determinants of Malawi's (...) traditional authorities receiving aid according to health, environmental risk, socioeconomic and political factors. We use two approaches to estimate the impact of aid on reducing malaria prevalence and increasing healthcare quality: difference-in-difference models, which include traditional authority and month-of-interview fixed effects and control for individual and household level time-varying factors, and entropy balancing, where models balance on health-related and socioeconomic baseline