Latest & greatest articles for adverse events

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Top results for adverse events

101. Coding of adverse events of suicidality in clinical study reports of duloxetine for the treatment of major depressive disorder: descriptive study.

Coding of adverse events of suicidality in clinical study reports of duloxetine for the treatment of major depressive disorder: descriptive study. OBJECTIVE: To assess the effects of coding and coding conventions on summaries and tabulations of adverse events data on suicidality within clinical study reports. DESIGN: Systematic electronic search for adverse events of suicidality in tables, narratives, and listings of adverse events in individual patients within clinical study reports. Where (...) possible, for each event we extracted the original term reported by the investigator, the term as coded by the medical coding dictionary, medical coding dictionary used, and the patient's trial identification number. Using the patient's trial identification number, we attempted to reconcile data on the same event between the different formats for presenting data on adverse events within the clinical study report. SETTING: 9 randomised placebo controlled trials of duloxetine for major depressive

BMJ2014

102. Risk of Thiazide-Induced Metabolic Adverse Events in Older Adults

Risk of Thiazide-Induced Metabolic Adverse Events in Older Adults 24823661 2014 06 13 2014 08 19 2017 02 20 1532-5415 62 6 2014 Jun Journal of the American Geriatrics Society J Am Geriatr Soc Risk of thiazide-induced metabolic adverse events in older adults. 1039-45 10.1111/jgs.12839 To evaluate the risk and predictors of thiazide-induced adverse events (AEs) in multimorbid older adults in real-world clinical settings. Observational cohort study. National Veterans Affairs data from 2007 to 2008 (...) Antihypertensive Agents adverse effects Cohort Studies Female Humans Male Metabolic Diseases chemically induced Risk Assessment Thiazides adverse effects NIHMS574830 PMC4128471 aged, adverse effects hypertension outcome assessment (health care) sodium chloride symporter inhibitors 2014 5 15 6 0 2014 5 16 6 0 2014 8 20 6 0 ppublish 24823661 10.1111/jgs.12839 PMC4128471 NIHMS574830

EvidenceUpdates2014 Full Text: Link to full Text with Trip Pro

103. Developing a risk model for in-hospital adverse events following implantable cardioverter-defibrillator implantation: a report from the NCDR (National Cardiovascular Data Registry)

Developing a risk model for in-hospital adverse events following implantable cardioverter-defibrillator implantation: a report from the NCDR (National Cardiovascular Data Registry) 24333491 2014 02 28 2014 04 22 2016 10 19 1558-3597 63 8 2014 Mar 04 Journal of the American College of Cardiology J. Am. Coll. Cardiol. Developing a risk model for in-hospital adverse events following implantable cardioverter-defibrillator implantation: a report from the NCDR (National Cardiovascular Data Registry (...) ). 788-96 10.1016/j.jacc.2013.09.079 S0735-1097(13)06284-0 To better inform patients and physicians of the expected risk of adverse events and to assist hospitals' efforts to improve the outcomes of patients undergoing implantable cardioverter-defibrillator (ICD) implantation, we developed and validated a risk model using data from the NCDR (National Cardiovascular Data Registry) ICD Registry. ICD prolong life in selected patients, but ICD implantation carries the risk of periprocedural complications

EvidenceUpdates2014 Full Text: Link to full Text with Trip Pro

104. Safe Administration of Systemic Cancer Therapy Part 2: Administration of Chemotherapy and Management of Preventable Adverse Events

Safe Administration of Systemic Cancer Therapy Part 2: Administration of Chemotherapy and Management of Preventable Adverse Events

Cancer Care Ontario2014

105. Systematic review and meta-analysis: Need for standardising adverse event reporting in testosterone trials

Systematic review and meta-analysis: Need for standardising adverse event reporting in testosterone trials Need for standardising adverse event reporting in testosterone trials | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword (...) Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Need for standardising adverse event reporting in testosterone trials Article Text Aetiology Systematic review and meta-analysis Need for standardising adverse event reporting in testosterone trials Shehzad Basaria Statistics from Altmetric.com No Altmetric data available for this article. Commentary on: Xu L , Freeman G

Evidence-Based Medicine (Requires free registration)2014

106. Is Ambulatory Laparoscopic Roux-En-Y Gastric Bypass Associated With Higher Adverse Events?

Is Ambulatory Laparoscopic Roux-En-Y Gastric Bypass Associated With Higher Adverse Events? 24169190 2014 01 08 2014 03 03 2014 01 08 1528-1140 259 2 2014 Feb Annals of surgery Ann. Surg. Is ambulatory laparoscopic Roux-en-Y gastric bypass associated with higher adverse events? 286-92 10.1097/SLA.0000000000000227 To determine the impact of length of stay upon 30-day outcomes. It has been recommended the goal length of stay (LOS) after laparoscopic Roux-en-Y gastric bypass (LRYGB) should be 1 day

EvidenceUpdates2014

107. Case control study: Higher levels of nurse staffing are not associated with reduced adverse events among postoperative children if surveillance levels are low

Case control study: Higher levels of nurse staffing are not associated with reduced adverse events among postoperative children if surveillance levels are low Higher levels of nurse staffing are not associated with reduced adverse events among postoperative children if surveillance levels are low | Evidence-Based Nursing This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers (...) of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Higher levels of nurse staffing are not associated with reduced adverse events among postoperative children if surveillance levels are low Article Text Nursing issues Case control study Higher levels of nurse staffing

Evidence-Based Nursing (Requires free registration)2014

108. Rates of medical errors and preventable adverse events among hospitalized children following implementation of a resident handoff bundle.

Rates of medical errors and preventable adverse events among hospitalized children following implementation of a resident handoff bundle. IMPORTANCE: Handoff miscommunications are a leading cause of medical errors. Studies comprehensively assessing handoff improvement programs are lacking. OBJECTIVE: To determine whether introduction of a multifaceted handoff program was associated with reduced rates of medical errors and preventable adverse events, fewer omissions of key data in written (...) , a verbal mnemonic, and a new team handoff structure. On one unit, a computerized handoff tool linked to the electronic medical record was introduced. MAIN OUTCOMES AND MEASURES: The primary outcomes were the rates of medical errors and preventable adverse events measured by daily systematic surveillance. The secondary outcomes were omissions in the printed handoff document and resident time-motion activity. RESULTS: Medical errors decreased from 33.8 per 100 admissions (95% CI, 27.3-40.3) to 18.3 per

JAMA2013

109. Neurological adverse events of new generation sodium blocker antiepileptic drugs. Meta-analysis of randomized, double-blinded studies with eslicarbazepine acetate, lacosamide and oxcarbazepine

Neurological adverse events of new generation sodium blocker antiepileptic drugs. Meta-analysis of randomized, double-blinded studies with eslicarbazepine acetate, lacosamide and oxcarbazepine Neurological adverse events of new generation sodium blocker antiepileptic drugs. Meta-analysis of randomized, double-blinded studies with eslicarbazepine acetate, lacosamide and oxcarbazepine Neurological adverse events of new generation sodium blocker antiepileptic drugs. Meta-analysis of randomized (...) , double-blinded studies with eslicarbazepine acetate, lacosamide and oxcarbazepine Zaccara G, Giovannelli F, Maratea D, Fadda V, Verrotti A CRD summary The authors concluded that antiepileptic drugs may cause neurological adverse events in patients with drug resistant epilepsy, which can limit their use and impair treatment success; higher doses of oxcarbazepine were associated with more frequent adverse events. The evidence had several limitations and the findings were not weighed against drug

DARE.2013

110. Risk of major adverse cardiac events following noncardiac surgery in patients with coronary stents.

Risk of major adverse cardiac events following noncardiac surgery in patients with coronary stents. IMPORTANCE: Guidelines recommend delaying noncardiac surgery in patients after coronary stent procedures for 1 year after drug-eluting stents (DES) and for 6 weeks after bare metal stents (BMS). The evidence underlying these recommendations is limited and conflicting. OBJECTIVE: To determine risk factors for adverse cardiac events in patients undergoing noncardiac surgery following coronary stent (...) implantation. DESIGN, SETTING, AND PARTICIPANTS: A national, retrospective cohort study of 41,989 Veterans Affairs (VA) and non-VA operations occurring in the 24 months after a coronary stent implantation between 2000 and 2010. Nonlinear generalized additive models examined the association between timing of surgery and stent type with major adverse cardiac events (MACE) adjusting for patient, surgery, and cardiac risk factors. A nested case-control study assessed the association between perioperative

JAMA2013

111. Autoimmune, neurological, and venous thromboembolic adverse events after immunisation of adolescent girls with quadrivalent human papillomavirus vaccine in Denmark and Sweden: cohort study.

Autoimmune, neurological, and venous thromboembolic adverse events after immunisation of adolescent girls with quadrivalent human papillomavirus vaccine in Denmark and Sweden: cohort study. OBJECTIVE: To assess the risk of serious adverse events after vaccination of adolescent girls with quadrivalent human papillomavirus (qHPV) vaccine. DESIGN: Register based cohort study. SETTING: Denmark and Sweden, October 2006 to December 2010. PARTICIPANTS: 997,585 girls aged 10-17, among whom 296,826 (...) and autoimmune, neurological, and venous thromboembolic adverse events. Although associations for three autoimmune events were initially observed, on further assessment these were weak and not temporally related to vaccine exposure. Furthermore, the findings need to be interpreted considering the multiple outcomes assessed.

BMJ2013 Full Text: Link to full Text with Trip Pro

112. Surgical adverse events: a systematic review

Surgical adverse events: a systematic review Surgical adverse events: a systematic review Surgical adverse events: a systematic review Anderson O, Davis R, Hanna GB, Vincent CA CRD summary This review aimed to identify the adverse events associated with surgery to help target patient safety improvement efforts. The authors concluded that efforts should not only target errors in surgical technique but also non-operative management. The evidence base was insufficient to completely answer (...) the review question. The findings should be interpreted with caution as they may not be reliable. Authors' objectives To identify the adverse events associated with surgery to help target patient safety improvement efforts. Searching Five databases including MEDLINE and the Cochrane Library were searched up to February 2011 for peer-reviewed articles in English. Search strategies were reported in supplementary data. Reference lists from eligible articles were searched manually. Study selection Clinical

DARE.2013

113. Severe adverse events during antiviral therapy in hepatitis C virus cirrhotic patients: a systematic review

Severe adverse events during antiviral therapy in hepatitis C virus cirrhotic patients: a systematic review Severe adverse events during antiviral therapy in hepatitis C virus cirrhotic patients: a systematic review Severe adverse events during antiviral therapy in hepatitis C virus cirrhotic patients: a systematic review Bota S, Sporea I, Sirli R, Popescu A, Neghina AM, Danila M, Strain M CRD summary The review concluded that 14.5% of cirrhotic patients infected with hepatitis C virus treated (...) with pegylated interferon and ribavirin needed early discontinuation of therapy due to severe adverse events. Differences between the included studies and a lack of quality assessment mean that the authors' conclusions may not reflect the proportion of patients requiring early discontinuation in practice. Authors' objectives To investigate the severe adverse events that lead to treatment discontinuation during treatment with pegylated interferon and ribavirin antiviral therapy in cirrhotic patients infected

DARE.2013

114. Aliskiren increased adverse events in patients with diabetes and kidney disease who were receiving ACE inhibitors or ARBs.

Aliskiren increased adverse events in patients with diabetes and kidney disease who were receiving ACE inhibitors or ARBs. ACP Journal Club. Aliskiren increased adverse events in patients with diabetes and kidney disease who were receiving ACE inhibitors or ARBs. - PubMed - NCBI Warning: The NCBI web site requires JavaScript to function. Search database Search term Search Result Filters Format Summary Summary (text) Abstract Abstract (text) MEDLINE XML PMID List Apply Choose Destination File (...) Clipboard Collections E-mail Order My Bibliography Citation manager Format Create File 1 selected item: 23552833 Format MeSH and Other Data E-mail Subject Additional text E-mail Add to Clipboard Add to Collections Order articles Add to My Bibliography Generate a file for use with external citation management software. Create File 2013 Mar 19;158(6):JC7. doi: 10.7326/0003-4819-158-6-201303190-02007. ACP Journal Club. Aliskiren increased adverse events in patients with diabetes and kidney disease who were

Annals of Internal Medicine2013

115. Meta-analysis of randomized trials of angioedema as an adverse event of renin-angiotensin system inhibitors

Meta-analysis of randomized trials of angioedema as an adverse event of renin-angiotensin system inhibitors Meta-analysis of randomized trials of angioedema as an adverse event of renin-angiotensin system inhibitors Meta-analysis of randomized trials of angioedema as an adverse event of renin-angiotensin system inhibitors Makani H, Messerli FH, Romero J, Wever-Pinzon O, Korniyenko A, Sevilla Berrios R, Bangalore S CRD summary This review found that the risk of angio-oedema with angiotensin (...) trials of angioedema as an adverse event of renin-angiotensin system inhibitors. American Journal of Cardiology 2012; 110(3): 383-391 PubMedID DOI Original Paper URL Indexing Status Subject indexing assigned by NLM MeSH Angioedema /chemically induced; Angiotensins /antagonists & Female; Humans; Male; Middle Aged; Randomized Controlled Trials as Topic; Renin /antagonists & Renin-Angiotensin System /drug effects; inhibitors; inhibitors AccessionNumber 12012036646 Date bibliographic record published 18

DARE.2013

116. Cohort study: Lack of association between proton pump inhibitors and adverse events in patients taking clopidogrel and aspirin

Cohort study: Lack of association between proton pump inhibitors and adverse events in patients taking clopidogrel and aspirin Lack of association between proton pump inhibitors and adverse events in patients taking clopidogrel and aspirin | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name (...) or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Lack of association between proton pump inhibitors and adverse events in patients taking clopidogrel and aspirin Article Text Aetiology Cohort study Lack of association between proton pump inhibitors and adverse events in patients taking clopidogrel and aspirin Ron Waksman 1

Evidence-Based Medicine (Requires free registration)2013

117. Review: SSRIs and TCAs equally effective at treating chronic depression and dysthemia; SSRIs are associated with fewer adverse events than TCAs

Review: SSRIs and TCAs equally effective at treating chronic depression and dysthemia; SSRIs are associated with fewer adverse events than TCAs Review: SSRIs and TCAs equally effective at treating chronic depression and dysthemia; SSRIs are associated with fewer adverse events than TCAs | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers (...) of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: SSRIs and TCAs equally effective at treating chronic depression and dysthemia; SSRIs are associated with fewer adverse events than TCAs Article Text Therapeutics Review: SSRIs and TCAs equally effective

Evidence-Based Mental Health2013

118. Adults with psychosis or psychotic experiences may report adverse life events prior to the onset of symptoms but direction of causality cannot be inferred

Adults with psychosis or psychotic experiences may report adverse life events prior to the onset of symptoms but direction of causality cannot be inferred Adults with psychosis or psychotic experiences may report adverse life events prior to the onset of symptoms but direction of causality cannot be inferred | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts (...) OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Adults with psychosis or psychotic experiences may report adverse life events prior to the onset of symptoms but direction of causality cannot be inferred Article Text Aetiology Adults with psychosis

Evidence-Based Mental Health2013

119. Adverse events risk associated with bevacizumab addition to breast cancer chemotherapy: a meta-analysis

Adverse events risk associated with bevacizumab addition to breast cancer chemotherapy: a meta-analysis Adverse events risk associated with bevacizumab addition to breast cancer chemotherapy: a meta-analysis Adverse events risk associated with bevacizumab addition to breast cancer chemotherapy: a meta-analysis Cortes J, Calvo V, Ramirez-Merino N, O'Shaughnessy J, Brufsky A, Robert N, Vidal M, Munoz E, Perez J, Dawood S, Saura C, Di Cosimo S, Gonzalez-Martin A, Bellet M, Silva OE, Miles D (...) , Llombart A, Baselga J CRD summary The authors concluded that bevacizumab was associated with an increased risk of hypertension, proteinuria, left ventricular dysfunction and bleeding, but not of gastrointestinal perforation, arterial or venous thromboembolic events and fatal events, in patients with metastatic breast cancer. Given the unclear quality and small number of included trials, the reliability of the authors' conclusions is unclear. Authors' objectives To assess the risk of severe adverse

DARE.2013