Latest & greatest articles for adverse events

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This page lists the very latest high quality evidence on adverse events and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Top results for adverse events

201. The effect of electronic prescribing on medication errors and adverse drug events: a systematic review

The effect of electronic prescribing on medication errors and adverse drug events: a systematic review The effect of electronic prescribing on medication errors and adverse drug events: a systematic review The effect of electronic prescribing on medication errors and adverse drug events: a systematic review Ammenwerth E, Schnell-Inderst P, Machan C, Siebert U CRD summary The authors concluded that electronic prescribing can reduce medication errors and adverse drug events, but studies differed (...) substantially in design, quality and findings. Although the direction of effect in the primary studies was generally consistent, the conclusions should be regarded with some caution due to the overall poor quality of the evidence. Authors' objectives To assess the effect of electronic prescribing on medication errors and adverse drug events (ADEs). Searching MEDLINE, EMBASE and Cochrane Database of Systematic Reviews were searched without language restriction. Search terms were reported. The Journal

DARE.2008

202. Pioglitazone and the risk of myocardial infarction and other major adverse cardiac events: a meta-analysis of randomized, controlled trials

Pioglitazone and the risk of myocardial infarction and other major adverse cardiac events: a meta-analysis of randomized, controlled trials Pioglitazone and the risk of myocardial infarction and other major adverse cardiac events: a meta-analysis of randomized, controlled trials Pioglitazone and the risk of myocardial infarction and other major adverse cardiac events: a meta-analysis of randomized, controlled trials Nagajothi N, Adigopula S, Balamuthusamy S, Velazquez-Cecena J L, Raghunathan K (...) and revascularisation were not statistically significant and may not be reliable. Implications of the review for practice and research The authors did not state any implications for practice or research. Funding Not stated. Bibliographic details Nagajothi N, Adigopula S, Balamuthusamy S, Velazquez-Cecena J L, Raghunathan K, Khraisat A, Singh S, Molnar J, Khosla S, Benatar D. Pioglitazone and the risk of myocardial infarction and other major adverse cardiac events: a meta-analysis of randomized

DARE.2008

203. Anticoagulation control and prediction of adverse events in patients with atrial fibrillation: a systematic review

Anticoagulation control and prediction of adverse events in patients with atrial fibrillation: a systematic review Anticoagulation control and prediction of adverse events in patients with atrial fibrillation: a systematic review Anticoagulation control and prediction of adverse events in patients with atrial fibrillation: a systematic review Wan Y, Heneghan C, Perera R, Roberts N, Hollowell J, Glasziou P, Bankhead C, Xu Y CRD summary This review concluded that in atrial fibrillation patients (...) receiving orally administered anticoagulation, time in therapeutic range and percentage of international normalised ratio (INRs) in range effectively predicted INR control; time in therapeutic range accurately predicted reductions adverse events. The review was generally well conducted, but the lack of quality assessment of included studies limits the reliability of the authors’ conclusions. Authors' objectives To determine the relationship between different outcome measures and adverse events in

DARE.2008

204. Inhaled anticholinergics and risk of major adverse cardiovascular events in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis

Inhaled anticholinergics and risk of major adverse cardiovascular events in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis Inhaled anticholinergics and risk of major adverse cardiovascular events in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis Inhaled anticholinergics and risk of major adverse cardiovascular events in patients with chronic obstructive pulmonary disease: a systematic review and meta (...) cardiovascular adverse events including myocardial infarction, stroke or cardiovascular death. Patients with asthma were excluded. The primary outcome was a composite of non-fatal acute myocardial infarction, non-fatal stroke (including transient ischemic attack) and cardiovascular death (including sudden death).The mean age ranged from 48.4 years to 68.1 years and, on average, men accounted for 72% of patients. Follow-up duration ranged from six weeks to 280 weeks. Two reviewers independently assessed

DARE.2008

205. Adverse events associated with ketamine for procedural sedation in adults

Adverse events associated with ketamine for procedural sedation in adults Adverse events associated with ketamine for procedural sedation in adults Adverse events associated with ketamine for procedural sedation in adults Strayer RJ, Nelson LS CRD summary The review concluded that when ketamine was used for procedural sedation in adults, cardiorespiratory adverse events were rare but dysphoric emergence phenomena occurred in 10% to 20% patients and there was a likelihood of airway obstruction (...) Assessment Reports from European Medicines Evaluation Agency, FDA Safety Information and Adverse Events Reporting Program and UK Current Problems in Pharmacovigilance were searched, as were selected books and review articles in the fields of emergency medicine, anaesthesiology, and clinical pharmacology literature and bibliographies of included articles. Selected experts in the field were contacted for unpublished studies. Study selection Trials that evaluated adverse effects of the use of ketamine

DARE.2008

206. Glycaemic control and adverse events in patients with type 2 diabetes treated with metformin + sulphonylurea: a meta-analysis

Glycaemic control and adverse events in patients with type 2 diabetes treated with metformin + sulphonylurea: a meta-analysis Glycaemic control and adverse events in patients with type 2 diabetes treated with metformin + sulphonylurea: a meta-analysis Glycaemic control and adverse events in patients with type 2 diabetes treated with metformin + sulphonylurea: a meta-analysis Belsey J, Krishnarajah G CRD summary This review of that adding sulphonylureas to the treatment of patients (...) with type 2 diabetes not controlled by metformin would reduce glycated haemoglobin by no more than 1% and may increase side-effects. Despite poor reporting of some aspects of the review process, the conclusions reflected the results of the review and appear likely to be reliable. Authors' objectives To quantify the effect of a sulphonylurea on glycaemic control and the risk of adverse events when incorporated into the treatment regimen of patients with type 2 diabetes inadequately controlled by metformin

DARE.2008

207. Telmisartan and ramipril were equivalent, but their combination increased adverse events in vascular disease or diabetes

Telmisartan and ramipril were equivalent, but their combination increased adverse events in vascular disease or diabetes Telmisartan and ramipril were equivalent, but their combination increased adverse events in vascular disease or diabetes | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user (...) name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Telmisartan and ramipril were equivalent, but their combination increased adverse events in vascular disease or diabetes Article Text Therapeutics Telmisartan and ramipril were equivalent, but their combination increased adverse events in vascular disease

Evidence-Based Medicine (Requires free registration)2008

208. Review: Children and adolescents with schizophrenia spectrum disorders respond to antipsychotics, but are susceptible to adverse events

Review: Children and adolescents with schizophrenia spectrum disorders respond to antipsychotics, but are susceptible to adverse events Review: Children and adolescents with schizophrenia spectrum disorders respond to antipsychotics, but are susceptible to adverse events | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts (...) Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: Children and adolescents with schizophrenia spectrum disorders respond to antipsychotics, but are susceptible to adverse events Article Text Therapeutics Review: Children and adolescents with schizophrenia spectrum disorders

Evidence-Based Mental Health2008

209. Medication use leading to emergency department visits for adverse drug events in older adults.

Medication use leading to emergency department visits for adverse drug events in older adults. BACKGROUND: The Beers criteria identify inappropriate use of medications in older adults. The number of and risk for adverse events from these medications are unknown. OBJECTIVE: To estimate the number of and risk for emergency department visits for adverse events involving Beers criteria medications compared with other medications. DESIGN: Nationally representative, public health surveillance (...) of adverse drug events and a cross-sectional survey of outpatient medical visits. SETTING: National Electronic Injury Surveillance System-Cooperative Adverse Drug Event Surveillance System, 2004-2005; National Ambulatory Medical Care Survey, 2004; and National Hospital Ambulatory Medical Care Survey, 2004. PARTICIPANTS: Persons 65 years of age or older seeking emergency department and outpatient care. MEASUREMENTS: Estimated number of and risks for emergency department visits for adverse drug events

Annals of Internal Medicine2007

210. Substance use and a history of psychosis are risk factors for serious adverse events in people with bipolar disorder

Substance use and a history of psychosis are risk factors for serious adverse events in people with bipolar disorder Substance use and a history of psychosis are risk factors for serious adverse events in people with bipolar disorder | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name (...) or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Substance use and a history of psychosis are risk factors for serious adverse events in people with bipolar disorder Article Text Aetiology Substance use and a history of psychosis are risk factors for serious adverse events in people with bipolar disorder Statistics from

Evidence-Based Mental Health2007

212. Meta-analysis: the effect of supplementation with probiotics on eradication rates and adverse events during Helicobacter pylori eradication therapy

Meta-analysis: the effect of supplementation with probiotics on eradication rates and adverse events during Helicobacter pylori eradication therapy Meta-analysis: the effect of supplementation with probiotics on eradication rates and adverse events during Helicobacter pylori eradication therapy Meta-analysis: the effect of supplementation with probiotics on eradication rates and adverse events during Helicobacter pylori eradication therapy Tong J L, Ran Z H, Shen J, Zhang C X, Xiao S D CRD (...) summary The authors concluded that the addition of probiotics to Helicobacter pylori (H. pylori) eradication regimens may increase H. pylori eradication rates and reduce side-effects. This was generally a well-conducted review and the authors' conclusions are likely to be reliable. Authors' objectives To evaluate the effects of adding probiotics to anti-Helicobacter pylori (H. pylori) regimens on H. pylori eradication rates and adverse effects. Searching PubMed, EMBASE, the Cochrane CENTRAL Register

DARE.2007

213. Adverse events associated with pediatric spinal manipulation: a systematic review

Adverse events associated with pediatric spinal manipulation: a systematic review Adverse events associated with pediatric spinal manipulation: a systematic review Adverse events associated with pediatric spinal manipulation: a systematic review Vohra S, Johnston B C, Cramer K, Humphreys K CRD summary The authors concluded that spinal manipulation in children can be associated with serious adverse events, but the incidence of such events cannot be determined from observational studies (...) . This was generally a well-conducted review and the authors’ conclusions are likely to be reliable. Authors' objectives To examine data on adverse events associated with paediatric spinal manipulation. Searching MEDLINE, PubMed, EMBASE, CINAHL, AltHealthWatch, MANTIS and ICL were searched from inception to June 2004. Details of the search strategy were reported as being available on request. No language restrictions were applied. In addition, reference lists were screened and authors of relevant studies

DARE.2007

214. Impact of inhaled corticosteroid-induced oropharyngeal adverse events: results from a meta-analysis

Impact of inhaled corticosteroid-induced oropharyngeal adverse events: results from a meta-analysis Impact of inhaled corticosteroid-induced oropharyngeal adverse events: results from a meta-analysis Impact of inhaled corticosteroid-induced oropharyngeal adverse events: results from a meta-analysis Rachelefsky G S, Liao Y, Faruqi R CRD summary This review assessed oropharyngeal adverse events associated with corticosteroid inhalation in participants with persistent asthma. The authors concluded (...) that inhaled corticosteroids can be associated with oropharyngeal adverse events; these may be reduced by post-dose mouth rinsing or the use of spacers. Despite the methodological problems of the review, the first part of the conclusion appears to be consistent with the data presented. Authors' objectives To assess the risk of inhaled corticosteroid (ICS)-induced oral candidiasis, dysphonia and pharyngitis among currently available therapies, and to determine associated effects of dose and device

DARE.2007

215. Meta-analysis of drug-induced adverse events associated with intensive-dose statin therapy

Meta-analysis of drug-induced adverse events associated with intensive-dose statin therapy Meta-analysis of drug-induced adverse events associated with intensive-dose statin therapy Meta-analysis of drug-induced adverse events associated with intensive-dose statin therapy Silva M, Matthews M L, Jarvis C, Nolan N M, Belliveau P, Malloy M, Gandhi P CRD summary The authors concluded that intensive-dose statin therapy significantly reduced the risk of a serious cardiovascular event but increased (...) the risk of a statin-induced adverse event, compared with moderate dose therapy. The reliability of these conclusions is uncertain due to methodological weaknesses in the review such as failure to assess study validity or check for heterogeneity between the studies. Authors' objectives To quantify the incremental risks associated with intensive-dose statin therapy, compared with moderate-dose statin therapy. Searching MEDLINE, EMBASE and the Cochrane Central Register of Controlled Trials were searched

DARE.2007

216. An economic model of adverse events and costs for oral anticoagulants used for atrial fibrillation

An economic model of adverse events and costs for oral anticoagulants used for atrial fibrillation An economic model of adverse events and costs for oral anticoagulants used for atrial fibrillation An economic model of adverse events and costs for oral anticoagulants used for atrial fibrillation Leigh J P, White R H Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods (...) , the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary This study examined the clinical and economic impact of warfarin versus a second anticoagulant in hypothetical cohort of 70-year-old patients with atrial fibrillation. There was substantial variation in rates and costs of adverse events when considering all possible scenarios, but the difference in costs between the two drugs was modest. Overall, the analysis

NHS Economic Evaluation Database.2007

217. Cost-effectiveness of an electronic medication ordering and administration system in reducing adverse drug events

Cost-effectiveness of an electronic medication ordering and administration system in reducing adverse drug events Cost-effectiveness of an electronic medication ordering and administration system in reducing adverse drug events Cost-effectiveness of an electronic medication ordering and administration system in reducing adverse drug events Wu R C, Laporte A, Ungar W J Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each (...) abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The study examined an electronic medication order entry system (MOE) versus the standard paper ordering system. MOE was designed to reduce adverse drug events (ADEs) that might cause significant morbidity and mortality. With MOE, doctors were provided with a menu of medications from the formulary and typical

NHS Economic Evaluation Database.2007

218. Rofecoxib and cardiovascular adverse events in adjuvant treatment of colorectal cancer.

Rofecoxib and cardiovascular adverse events in adjuvant treatment of colorectal cancer. 17652651 2007 07 26 2007 07 31 2014 11 20 1533-4406 357 4 2007 Jul 26 The New England journal of medicine N. Engl. J. Med. Rofecoxib and cardiovascular adverse events in adjuvant treatment of colorectal cancer. 360-9 Selective cyclooxygenase inhibitors may retard the progression of cancer, but they have enhanced thrombotic potential. We report on cardiovascular adverse events in patients receiving rofecoxib (...) to reduce rates of recurrence of colorectal cancer. All serious adverse events that were cardiovascular thrombotic events were reviewed in 2434 patients with stage II or III colorectal cancer participating in a randomized, placebo-controlled trial of rofecoxib, 25 mg daily, started after potentially curative tumor resection and chemotherapy or radiotherapy as indicated. The trial was terminated prematurely owing to worldwide withdrawal of rofecoxib. To examine possible persistent risks, we examined

NEJM2007

219. National surveillance of emergency department visits for outpatient adverse drug events.

National surveillance of emergency department visits for outpatient adverse drug events. CONTEXT: Adverse drug events are common and often preventable causes of medical injuries. However, timely, nationally representative information on outpatient adverse drug events is limited. OBJECTIVE: To describe the frequency and characteristics of adverse drug events that lead to emergency department visits in the United States. DESIGN, SETTING, AND PARTICIPANTS: Active surveillance from January 1, 2004 (...) , through December 31, 2005, through the National Electronic Injury Surveillance System-Cooperative Adverse Drug Event Surveillance project. MAIN OUTCOME MEASURES: National estimates of the numbers, population rates, and severity (measured by hospitalization) of individuals with adverse drug events treated in emergency departments. RESULTS: Over the 2-year study period, 21,298 adverse drug event cases were reported, producing weighted annual estimates of 701,547 individuals (95% confidence interval [CI

JAMA2006

220. Warfarin was not more effective than aspirin and increased adverse events in symptomatic intracranial arterial stenosis

Warfarin was not more effective than aspirin and increased adverse events in symptomatic intracranial arterial stenosis Warfarin was not more effective than aspirin and increased adverse events in symptomatic intracranial arterial stenosis | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name (...) or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Warfarin was not more effective than aspirin and increased adverse events in symptomatic intracranial arterial stenosis Article Text Therapeutics Warfarin was not more effective than aspirin and increased adverse events in symptomatic intracranial arterial stenosis Free John

Evidence-Based Medicine (Requires free registration)2006