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Latest & greatest articles for acute pain
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Pain over speed bumps in diagnosis of acute appendicitis: diagnostic accuracy study. OBJECTIVE: To assess the diagnostic accuracy of pain on travelling over speed bumps for the diagnosis of acute appendicitis. DESIGN: Prospective questionnaire based diagnostic accuracy study. SETTING: Secondary care surgical assessment unit at a district general hospital in the UK. PARTICIPANTS: 101 patients aged 17-76 years referred to the on-call surgical team for assessment of possible appendicitis. MAIN (...) OUTCOME MEASURES: Sensitivity, specificity, positive and negative predictive values, and positive and negative likelihood ratios for pain over speed bumps in diagnosing appendicitis, with histological diagnosis of appendicitis as the reference standard. RESULTS: The analysis included 64 participants who had travelled over speed bumps on their journey to hospital. Of these, 34 had a confirmed histological diagnosis of appendicitis, 33 of whom reported increased pain over speed bumps. The sensitivity
Failure of Prospective Validation and Derivation of a Refined Clinical Decision Rule for Chest Radiography in Emergency Department Patients With Chest Pain and Possible Acute Coronary Syndrome 22978726 2012 09 17 2013 03 06 2016 11 25 1553-2712 19 9 2012 Sep Academic emergency medicine : official journal of the Society for Academic Emergency Medicine Acad Emerg Med Failure of prospective validation and derivation of a refined clinical decision rule for chest radiography in emergency department (...) patients with chest pain and possible acute coronary syndrome. E1004-10 10.1111/j.1553-2712.2012.01428.x The authors previously derived a clinical decision rule (CDR) for chest radiography in patients with chest pain and possible acute coronary syndrome (ACS) consisting of the absence of three predictors: history of congestive heart failure, history of smoking, and abnormalities on lung auscultation. The aim of the investigation was to prospectively validate and refine the CDR for chest radiography in
Efficacy of 10 % Sucralfate Ointment in the Reduction of Acute Postoperative Pain After Open Hemorrhoidectomy: A Prospective, Double-Blind, Randomized, Placebo-Controlled Trial 23010700 2012 12 24 2013 05 28 2013 09 12 1432-2323 37 1 2013 Jan World journal of surgery World J Surg Efficacy of 10% sucralfate ointment in the reduction of acute postoperative pain after open hemorrhoidectomy: a prospective, double-blind, randomized, placebo-controlled trial. 233-8 10.1007/s00268-012-1805-8 The aim (...) of the present study was to evaluate the efficacy of 10 % sucralfate ointment in the reduction of acute postoperative pain after open hemorrhoidectomy. A total of 48 patients (24 men and 24 women) between 20 and 70 years of age who underwent open hemorrhoidectomy were included in this prospective, double-blind, randomized, controlled trial and were randomly divided into two groups (24 in each group), receiving either sucralfate ointment or placebo immediately after surgery and then every 12 h for 14 days
The role of regional anaesthesia techniques in the management of acutepain The role of regional anaesthesia techniques in the management of acutepain The role of regional anaesthesia techniques in the management of acutepain Cowlishaw PJ, Scott DM, Barrington MJ CRD summary The review concluded that regional anaesthesia/analgesia was superior to conventional therapy for management of postoperative pain following a range of surgical types. Variation in characteristics of the included studies (...) and potential for bias in the review process mean that the authors' conclusions should be considered tentative. Authors' objectives To assess the efficacy of regional anaesthesia and analgesia for the management of acutepain following surgery. Searching MEDLINE, EMBASE and Cochrane Central Register of Controlled Trials (CENTRAL) were searched for relevant studies published between March 2009 and March 2011. There were no language restrictions. Search terms were reported. Study selection Randomised
CT for acute chest pain CT for acute chest pain CT for acute chest pain Mitchell MD, Han Y, Hollander JE, Jha S, Williams K Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Mitchell MD, Han Y, Hollander JE, Jha S, Williams K. CT for acute chest pain. Philadelphia: Center for Evidence-based Practice (CEP). 2012 Final publication URL Indexing Status Subject (...) indexing assigned by CRD MeSH Chest Pain; Humans; Predictive Value of Tests; Tomography, X-Ray Computed Language Published English Country of organisation United States English summary An English language summary is available. Address for correspondence Center for Evidence-based Practice, University of Pennsylvania Health System, 3535 Market St. Suite 50, Philadelphia PA 19104 Email: Cep2@uphs.upenn.edu AccessionNumber 32012000266 Date abstract record published 06/07/2012 Health Technology Assessment
Sublingual buprenorphine in acutepain management: a double-blind randomized clinical trial 22115823 2012 03 27 2012 05 10 2013 11 21 1097-6760 59 4 2012 Apr Annals of emergency medicine Ann Emerg Med Sublingual buprenorphine in acutepain management: a double-blind randomized clinical trial. 276-80 10.1016/j.annemergmed.2011.10.021 We compare the efficacy and safety of sublingual buprenorphine versus intravenous morphine sulfate in emergency department adults with acute bone fracture. Enrolled (...) patients received buprenorphine 0.4 mg sublingually or morphine 5 mg intravenously in this double-blind, double-dummy, randomized controlled trial. Patients graded their pain with a standard 11-point numeric rating scale before medication administration and 30 and 60 minutes after, and we recorded adverse reactions. We analyzed 44 and 45 patients in the buprenorphine and morphine groups, respectively. Mean pain scores were similar at 30 minutes (5.0 versus 5.0; difference 0; 95% confidence interval
Fluid replacement therapy for acute episodes of pain in people with sickle cell disease. BACKGROUND: Treating vaso-occlusive painful crises in people with sickle cell disease is complex and requires multiple interventions. Extra fluids are routinely given as adjunct treatment, regardless of the individual's state of hydration with the aim of slowing or stopping the sickling process and thereby alleviating pain. OBJECTIVES: To determine the optimal route, quantity and type of fluid replacement (...) for people with sickle cell disease with acutepainful crises. SEARCH METHODS: We searched the Cochrane Cystic Fibrosis and Genetic Disorders Group Trials Register which comprises of references identified from comprehensive electronic database searches and handsearches of relevant journals and abstract books of conference proceedings.We also conducted searches of EMBASE (November 2007), LILACS and www.ClinicalTrials.gov (05 January 2010).Date of most recent search of the Group's Haemoglobinopathies
Occlusal Splint Is More Effective Than Transcutaneous Electric Nerve Stimulation In Reducing Pain Due To Acute TMJ Disc Displacement Without Reduction UTCAT2281, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Occlusal Splint Is More Effective Than Transcutaneous Electric Nerve Stimulation In Reducing Pain Due To Acute TMJ Disc Displacement Without Reduction Clinical Question In adults with a TMJ acute disc (...) displacement without reduction, will an occlusal splint or transcutaneous electric nerve stimulation be more effective in reducing TMD pain. Clinical Bottom Line Using a VAS, occlusal splints were found to be more effective in reducing pain in adult patients with a TMJ acute disc displacement without reduction. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Linde /1995 31 Patients Randomized Controlled Trial
Can pregabalin effectively diminish acute herpetic pain and reduce the incidence of post-herpetic neuralgia in patients who present with acute herpes zoster? BestBets: Can pregabalin effectively diminish acute herpetic pain and reduce the incidence of post-herpetic neuralgia in patients who present with acute herpes zoster? Can pregabalin effectively diminish acute herpetic pain and reduce the incidence of post-herpetic neuralgia in patients who present with acute herpes zoster? Report (...) By: Eliane Raymond-Dufresne - PGY-3, Emergency Medicine Search checked by Katharine Wylie - Senior Informatacist Institution: Laval University, Qu�bec, Canada Date Submitted: 23rd November 2011 Date Completed: 13th February 2012 Last Modified: 20th February 2012 Status: Green (complete) Three Part Question In [patients with new onset of herpes zoster infection], can [pregabalin] be used to [decrease the incidence of post-herpetic neuralgia and to decrease the intensity of acute herpetic pain]? Clinical
Diagnostic characteristics of S100A8/A9 in a multicenter study of patients with acute right lower quadrant abdominal pain 22221415 2012 01 18 2012 05 10 2015 11 19 1553-2712 19 1 2012 Jan Academic emergency medicine : official journal of the Society for Academic Emergency Medicine Acad Emerg Med Diagnostic characteristics of S100A8/A9 in a multicenter study of patients with acute right lower quadrant abdominal pain. 48-55 10.1111/j.1553-2712.2011.01259.x Over the past decade, clinicians have (...) become increasingly reliant on computed tomography (CT) for the evaluation of patients with suspected acute appendicitis. To limit the radiation risks and costs of CT, investigators have searched for biomarkers to aid in diagnostic decision-making. We evaluated one such biomarker, calprotectin or S100A8/A9, and determined the diagnostic performance characteristics of a developmental biomarker assay in a multicenter investigation of patients presenting with acute right lower quadrant abdominal pain
Tapentadol (Palexia) - relief of moderate to severe acutepain in adults Published 13 February, 2012 Statement of Advice tapentadol (Palexia®) 50 mg film-coated tablets (No: 773/12) Grunenthal Ltd 13 January 2012 ADVICE: in the absence of a submission from the holder of the marketing authorisation tapentadol (Palexia®) is not recommended for use within NHS Scotland. Indication under review: relief of moderate to severe acutepain in adults, which can be adequately managed only with opioid (...) analgesics. The holder of the marketing authorisation has not made a submission to SMC regarding this product in this indication. As a result we cannot recommend its use within NHSScotland. Advice context: No part of this advice may be used without the whole of the advice being quoted in full. This advice represents the view of the Scottish Medicines Consortium. It is provided to inform the considerations of Area Drug & Therapeutics Committees and NHS Boards in Scotland in determining medicines for local
Calcitonin for treating acute and chronic pain of recent and remote osteoporotic vertebral compression fractures: a systematic review and meta-analysis Calcitonin for treating acute and chronic pain of recent and remote osteoporotic vertebral compression fractures: a systematic review and meta-analysis Calcitonin for treating acute and chronic pain of recent and remote osteoporotic vertebral compression fractures: a systematic review and meta-analysis Knopp-Sihota JA, Newburn-Cook CV, Homik J (...) , Cummings GG, Voaklander D CRD summary The authors concluded that calcitonin has proven efficacy in the management of acute back pain associated with a recent osteoporotic vertebral compression fracture, but there was no convincing evidence to support its use to treat chronic back pain of the same origin. Limitations of the evidence suggest the statement that calcitonin has proven efficacy may be overly strong. Authors' objectives To evaluate the efficacy of calcitonin for treating acute and chronic
A randomized controlled trial of the effects of muscle stretching, manual therapy and steroid injections in addition to `stay active` care on health-related quality of life in acute or subacute low back pain 21831926 2011 11 10 2012 03 20 2011 11 10 1477-0873 25 11 2011 Nov Clinical rehabilitation Clin Rehabil A randomized controlled trial of the effects of muscle stretching, manual therapy and steroid injections in addition to 'stay active' care on health-related quality of life in acute (...) or subacute low back pain. 999-1010 10.1177/0269215511403512 To evaluate the health-related quality of life effects of muscle stretching, manual therapy and steroid injections in addition to 'stay active' care in acute or subacute low back pain patients. A randomized, controlled trial during 10 weeks with four treatment groups. Nine primary health care and one outpatient orthopaedic hospital department. One hundred and sixty patients with acute or subacute low back pain. Ten weeks of 'stay active' care
Coronary CT angiography versus standard evaluation in acute chest pain. 22830462 2012 07 26 2012 08 02 2016 12 15 1533-4406 367 4 2012 Jul 26 The New England journal of medicine N. Engl. J. Med. Coronary CT angiography versus standard evaluation in acute chest pain. 299-308 10.1056/NEJMoa1201161 It is unclear whether an evaluation incorporating coronary computed tomographic angiography (CCTA) is more effective than standard evaluation in the emergency department in patients with symptoms (...) Based Med. 2013 Aug;18(4):146-7 23213118 N Engl J Med. 2012 Jul 26;367(4):375-6 22830468 Acute Coronary Syndrome complications diagnosis diagnostic imaging Adult Aged Chest Pain diagnostic imaging etiology Coronary Angiography Electroencephalography Emergency Service, Hospital Female Health Care Costs Health Resources utilization Humans Length of Stay Male Middle Aged Tomography, X-Ray Computed NIHMS405222 PMC3662217 2012 7 27 6 0 2012 7 27 6 0 2012 8 3 6 0 ppublish 22830462 10.1056/NEJMoa1201161
Practice Guidelines for AcutePain Management in the Perioperative Setting Practice Guidelines for AcutePain Management in the Perioperative Setting:An Updated Report by the American Society of Anesthesiologists Task Force on AcutePain Management | Anesthesiology | ASA Publications 116205413 ASA Publications Log in to access full content You must be logged in to access this feature. ASA members enjoy complimentary access to ASA publications, as well as a variety of educational resources. Non (...) -ASA Members Login Free Practice Parameter | February 2012 Practice Guidelines for AcutePain Management in the Perioperative Setting: An Updated Report by the American Society of Anesthesiologists Task Force on AcutePain Management Article Information Practice Parameter / Pain Medicine / Pediatric Anesthesia / Quality Improvement Practice Parameter | February 2012 Practice Guidelines for AcutePain Management in the Perioperative Setting: An Updated Report by the American Society