Latest & greatest articles for acne

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on acne or other clinical topics then use Trip today.

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Acne treatment and clinical papers

Acne is a common skin condition characterised by whiteheads (or blackheads), pimples and oily skin. It can lead to possible scarring. It is typically caused when hair follicles become inflamed and the sebaceous glands in the skin are overactive. The over production of sebum and a combination of dead skin cells and dirt can clog follicles and pores causing a break out. Acne can affect any age group but it’s more common in adolescents.

There are many ways to treat acne depending on the severity of the case. Treatments include a range of medications such as topical retinoids, antibiotics and in severe cases isotretinoin is prescribed. Research is ongoing to determine the side effects and harms caused by these drugs. Clinical trials and studies are vital to assess treatment.

The Trip Database has an extensive collection of articles on acne ranging from clinical trials, systematic reviews, clinical guidelines and case reports. These can be found via searching the site.

Top results for acne

21. Light therapies for acne.

Light therapies for acne. BACKGROUND: Acne vulgaris is a very common skin problem that presents with blackheads, whiteheads, and inflamed spots. It frequently results in physical scarring and may cause psychological distress. The use of oral and topical treatments can be limited in some people due to ineffectiveness, inconvenience, poor tolerability or side-effects. Some studies have suggested promising results for light therapies. OBJECTIVES: To explore the effects of light treatment (...) of different wavelengths for acne. SEARCH METHODS: We searched the following databases up to September 2015: the Cochrane Skin Specialised Register, CENTRAL, MEDLINE, Embase and LILACS. We searched ISI Web of Science and Dissertation Abstracts International (from inception). We also searched five trials registers, and grey literature sources. We checked the reference lists of studies and reviews and consulted study authors and other experts in the field to identify further references to relevant randomised

Cochrane2016

22. Adalimumab (Humira) - treatment of active moderate to severe hidradenitis suppurativa (HS) (acne inversa)

Adalimumab (Humira) - treatment of active moderate to severe hidradenitis suppurativa (HS) (acne inversa)

Scottish Medicines Consortium2016

23. Certain Dairy Products Can Negatively Affect Acne Severity in Young Adult Korean and Malaysian Populations

Certain Dairy Products Can Negatively Affect Acne Severity in Young Adult Korean and Malaysian Populations "Certain Dairy Products Can Negatively Affect Acne Severity in Young Ad" by Velika Lotwala < > > > > > Title Author Date of Award Summer 8-13-2016 Degree Type Capstone Project Degree Name Master of Science in Physician Assistant Studies First Advisor Saje Davis-Risen, PA-C, MS Second Advisor Annjanette Sommers, PA-C, MS Rights . Abstract Background: Acne vulgaris is a widespread (...) and complex skin condition affecting mainly young adults in developed nations. The correlation between diet and acne has long been debated. Some medical providers routinely advised acne prone patients to refrain from eating excessive sugar and certain foods such as French fries or chocolate however other medical providers dismissed this idea as myth. Recent studies have demonstrated a relationship between certain dairy products and acne severity, particularly in young adult populations. Furthermore

Pacific University EBM Capstone Project2016

24. Rosacea - acne

Rosacea - acne Rosacea - acne - NICE CKS Clinical Knowledge Summaries Share Rosacea - acne: Summary Acne rosacea is a chronic relapsing skin condition affecting the face, characterized by recurrent episodes of facial flushing, erythema, telangiectasia, papules and pustules. There may be eye symptoms (ocular rosacea), which are usually bilateral. Acne rosacea can be classified into four types (erythematotelangiectatic, papulopustular, phymatous, and ocular) and one variant (granulomatous (...) depression in severe cases), ocular conditions (such as blepharitis, conjunctivitis, meibomian cyst, or keratitis), or rosacea fulminans (a severe form of acne rosacea). Diagnosis is usually made on the basis of one or more clinical features, typically affecting the convexities of the central face, and include: Flushing or transient erythema (pre-rosacea). Persistent erythema (erythematotelangiectatic rosacea). Telangiectasia (erythematotelangiectatic rosacea). Papules and pustules (papulopustular

NICE Clinical Knowledge Summaries2016

25. Guidelines of care for the management of acne vulgaris

Guidelines of care for the management of acne vulgaris FROM THE ACADEMY Guidelinesofcareforthemanagementofacnevulgaris Work Group: Andrea L. Zaenglein, MD (Co-Chair), a Arun L. Pathy, MD (Co-Chair), b Bethanee J. Schlosser, MD, PhD, c Ali Alikhan, MD, d Hilary E. Baldwin, MD, e Diane S. Berson, MD, f,g Whitney P. Bowe, MD, e Emmy M. Graber, MD, h,i Julie C. Harper, MD, j Sewon Kang, MD, k Jonette E. Keri, MD, PhD, l,m James J. Leyden, MD, n Rachel V. Reynolds, MD, o,p Nanette B. Silverberg, MD (...) , q,r Linda F. Stein Gold, MD, s Megha M. Tollefson, MD, t Jonathan S. Weiss, MD, u NancyC.Dolan,MD, c Andrew A. Sagan, MD, v Mackenzie Stern, c KevinM.Boyer,MPH, w and Reva Bhushan, MA, PhD w Hershey and Philadelphia, Pennsylvania; Centennial, Colorado; Chicago and Schaumburg, Illinois; Cincinnati, Ohio; New York, New York; Boston, Massachusetts; Birmingham, Alabama; Baltimore, Maryland;Miami,Florida;Detroit,Michigan;Rochester,Minnesota;andAtlanta,Georgia Acne is one of the most common disorders

American Academy of Dermatology2016

26. Is less more with isotretinoin and acne?

Is less more with isotretinoin and acne? Tools for Practice is proudly sponsored by the Alberta College of Family Physicians (ACFP). ACFP is a provincial, professional voluntary organization, representing more than 4,000 family physicians, family medicine residents and medical students in Alberta. Established over fifty years ago, the ACFP strives for excellence in family practice through advocacy, continuing medical education and primary care research. www.acfp.ca March 14, 2016 Is less more (...) with isotretinoin and acne? Clinical Question: What is the efficacy and tolerability of low-dose compared to conventional dose isotretinoin in the treatment of acne? Bottom-line: Small randomized controlled trials (RCTs) and observational studies demonstrate low-dose (~20mg/day) isotretinoin improves acne similar to conventional dosing. Low-dose may reduce common side effects (chapped lips, dry skin, epistaxis) by 16-35% but may be associated with increased relapse rates, particularly with severe acne

Tools for Practice2016

27. Management of acne

Management of acne Guidelines CMAJ ©2015 8872147 Canada Inc. or its licensors CMAJ 1 CME A cne is one of the most burdensome dis­ eases globally. 1,2 Its prevalence among those aged 12 to 24 years is estimated to be 85%, although it can persist beyond young adulthood despite treatment. 3–5 Acne can adversely affect quality of life 6–13 and may lead to emotional distress and physical scarring. 14,15 The clinical presentation of acne (Figure 1) varies from primarily comedonal to mixed comedonal (...) and inflammatory acne. 16 Since the last Canadian acne guideline was published in 2000, 17 evidence for multiple addi­ tional treatments has been published. Thus, there was an unmet need for an updated, systematic­ ally developed, evidence­ based Canadian acne clinical practice guideline. This guideline pro­ vides recommendations adapted to the Canadian health care system to assist Canadian health care providers in the diagnosis of acne vulgaris, including investigations where appropriate; it also provides

CMA Infobase (Canada)2015

28. Complementary therapies for acne: do they hit the spot?

Complementary therapies for acne: do they hit the spot? Complementary therapies for acne: do they hit the spot? - Evidently Cochrane Search and hit Go By February 6, 2015 // What a misery acne can be and few teens escape it completely. It can last well into adulthood too. There are many treatments available, both over-the-counter and on prescription. Many people look to alternatives to medical treatment, such as herbal preparations and changes to their diet. Are they any good? A team from set (...) out to find out. Their brought together the best available evidence from randomised controlled trials on complementary therapies for acne. There are 35 trials (over 3000 people) looking at herbal medicine, acupuncture, wet cupping, diet, purified bee venom, and tea tree oil. Here’s what they found: Low- versus high-glycaemic load diets were compared. There was no clear evidence of a difference between groups in the number of non-inflammatory lesions after 12 weeks (2 studies combined). The low

Evidently Cochrane2015

29. Antihistamine: A Useful Medication with Minimal Adverse Drug Reactions to Improve Acne Symptoms and Reduce Sebum Production

Antihistamine: A Useful Medication with Minimal Adverse Drug Reactions to Improve Acne Symptoms and Reduce Sebum Production "Antihistamine: A Useful Medication with Minimal Adverse Drug Reactions" by Lorraine Wang < > > > > > Title Author Date of Award Summer 8-8-2015 Degree Type Capstone Project Degree Name Master of Science in Physician Assistant Studies First Advisor David Keene PA-C Rights . Abstract Background: Acne vulgaris is a common skin disease that affects not only teenagers but also (...) the general population. Although acne is not physically disabling, its psychological impact can be striking, contributing to low self-esteem, depression, and anxiety. As a result, there is a significant demand for effective acne therapies. Antihistamine is a widely used medication to treat several allergic skin conditions and yet it also has been found to decrease complications of acne and improve acne symptoms. For the severe cystic acne vulgaris, oral retinoids such as isotretinoin is the primary

Pacific University EBM Capstone Project2015

30. The Effects of a Low Glycemic Load Diet on Acne Vulgaris in Adolescents and Young Adults

The Effects of a Low Glycemic Load Diet on Acne Vulgaris in Adolescents and Young Adults "The Effects of a Low Glycemic Load Diet on Acne Vulgaris in Adolescent" by Andrew White < > > > > > Title Author Date of Award Summer 8-8-2015 Degree Type Capstone Project Degree Name Master of Science in Physician Assistant Studies First Advisor Mark Pedemonte, MD Second Advisor Annjanette Sommers, PA-C, MS Rights . Abstract Background: Acne vulgaris is a common disease amongst adolescents in Western (...) societies. It is an interesting problem because, while it is very common among this particular population, it is very rare in non-Westernized societies. This observation has lead to recent exploration of what factors in Western society may, at least in part, be responsible for this. Recently there have been several epidemiological studies linking certain foods to acne. Of the foods showing a positive correlation, high glycemic load foods have been the most extensively studied. There have been a number

Pacific University EBM Capstone Project2015

33. Acne vulgaris

Acne vulgaris Acne vulgaris - NICE CKS Clinical Knowledge Summaries Share Acne vulgaris - Summary Acne vulgaris is a chronic skin condition in which blockage or inflammation of the hair follicles and accompanying sebaceous glands (known as pilosebaceous units) occurs. It principally affects the face, the back, and the chest, and usually first occurs around the age of puberty. Acne is most prevalent among adolescents and young adults, affecting approximately 80% of people at some point between (...) 11–30 years of age. Complications of acne include scarring, hyperpigmentation, and psychological problems. In general, it is recommended that people with acne: Do not wash more than twice a day. Use a mild soap or cleanser and lukewarm water. Do not use vigorous scrubbing when washing acne-affected skin, and the use of abrasive soaps, cleansing granules, astringents, or exfoliating agents should be discouraged. Should not attempt to 'clean' blackheads. Ideally, should avoid excessive use

NICE Clinical Knowledge Summaries2014

34. Methyl aminolevulinate (Visonac) photodynamic therapy for acne vulgaris

Methyl aminolevulinate (Visonac) photodynamic therapy for acne vulgaris Methyl aminolevulinate (Visonac) photodynamic therapy for acne vulgaris Methyl aminolevulinate (Visonac) photodynamic therapy for acne vulgaris NIHR HSC Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation NIHR HSC. Methyl aminolevulinate (Visonac) photodynamic therapy (...) for acne vulgaris. Birmingham: NIHR Horizon Scanning Centre (NIHR HSC). Horizon Scanning Review. 2013 Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Acne Vulgaris; Aminolevulinic Acids; Photochemotherapy Language Published English Country of organisation England English summary An English language summary is available. Address for correspondence The NIHR Horizon Scanning Centre, Department of Public Health, Epidemiology, and Biostatistics, School of Health&Population

Health Technology Assessment (HTA) Database.2013

35. Acne vulgaris.

Acne vulgaris. Acne is a chronic inflammatory disease of the pilosebaceous unit resulting from androgen-induced increased sebum production, altered keratinisation, inflammation, and bacterial colonisation of hair follicles on the face, neck, chest, and back by Propionibacterium acnes. Although early colonisation with P acnes and family history might have important roles in the disease, exactly what triggers acne and how treatment affects the course of the disease remain unclear. Other factors (...) such as diet have been implicated, but not proven. Facial scarring due to acne affects up to 20% of teenagers. Acne can persist into adulthood, with detrimental effects on self-esteem. There is no ideal treatment for acne, although a suitable regimen for reducing lesions can be found for most patients. Good quality evidence on comparative effectiveness of common topical and systemic acne therapies is scarce. Topical therapies including benzoyl peroxide, retinoids, and antibiotics when used in combination

Lancet2011

36. Adapalene 0.1% of Benzoyl Peroxide (Epiduo Gel) - cutaneous treatment of acne vulgaris when comedones, papules and pustules are present

Adapalene 0.1% of Benzoyl Peroxide (Epiduo Gel) - cutaneous treatment of acne vulgaris when comedones, papules and pustules are present

Scottish Medicines Consortium2011

37. Meta-analysis comparing efficacy of benzoyl peroxide, clindamycin, benzoyl peroxide with salicylic acid, and combination benzoyl peroxide/clindamycin in acne

Meta-analysis comparing efficacy of benzoyl peroxide, clindamycin, benzoyl peroxide with salicylic acid, and combination benzoyl peroxide/clindamycin in acne Meta-analysis comparing efficacy of benzoyl peroxide, clindamycin, benzoyl peroxide with salicylic acid, and combination benzoyl peroxide/clindamycin in acne Meta-analysis comparing efficacy of benzoyl peroxide, clindamycin, benzoyl peroxide with salicylic acid, and combination benzoyl peroxide/clindamycin in acne Seidler EM, Kimball AB (...) CRD summary The authors concluded that at two to four weeks, combination benzoyl peroxide plus salicylic acid had the best profile for treating acne vulgaris; at 10 to 12 weeks, this combination treatment was similar to benzoyl peroxide/clindamycin treatment. Potential limitations with the review process and the uncertain quality of included trials suggest that the authors’ conclusions should be treated with caution. Authors' objectives To compare the efficacy of benzoyl peroxide, clindamycin

DARE.2010

39. Acne best practice management

Acne best practice management RACGP - Acne – best practice management Username Password Password security changes or call 1800 284 789 Latest issue March 2017 Vol 46(3) 81-176 The March issue of AFP highlights a range of office-based procedures in general practice. Australian Family Physician Joint pain September 2010 / / / / Clinical Acne Best practice management Pages 656-660 David Cook George Krassas Tom Huang Background Acne vulgaris can have a substantial impact on a patient’s quality (...) of life; there can be significant psychosocial consequences and it can leave permanent physical scarring. Early and effective acne treatment is important. Objective/s To describe the outcome of an accredited clinical audit investigating general practitioner management of acne vulgaris and to provide an outline of current ‘best practice’ acne management. Discussion The audit was conducted over two cycles with GPs receiving educational material between cycles. Eighty-five GPs contributed data on 1638 patients

The Royal Australian College of General Practitioners2010

40. Advice on the safe introduction and continued use of isotretinoin in acne in the UK

Advice on the safe introduction and continued use of isotretinoin in acne in the UK GUIDELINES BJD British Journal of Dermatology Advice on the safe introduction and continued use of isotretinoin in acne in the U.K. 2010 M.J.D. Good?eld, N.H. Cox,* A. Bowser, J.C. McMillan, L.G. Millard,§ N.B. Simpson– and A.D. Ormerod** Department of Dermatology, Leeds General In?rmary, Leeds LS1 3EX, U.K. *Department of Dermatology, Cumberland In?rmary, Carlisle CA2 7HY, U.K. Independent Acne Patient Advisor (...) words adverse effects, depression, isotretinoin, pregnancy prevention plan, safe use, teratogen Con?icts of interest M.J.D.G. (Chair) has received no direct or indirect sponsorship from either of the companies that supply isotretinoin. The Department in which he works has received both speci?c and nonspeci?c sponsorship for research from Roche in the past. The late N.H.C. received sponsorship from Roche to attend nontargeted educational meetings. A.B. is Chief Executive of the Acne Support Group

British Association of Dermatologists2010