Latest & greatest articles for Wart Treatment

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on Wart Treatment or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on Wart Treatment and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for Wart Treatment

1. A systematic review evaluating the efficacy and safety of a combination of ablative treatment and self administered treatment versus ablative treatment alone for external anogenital warts. (Abstract)

A systematic review evaluating the efficacy and safety of a combination of ablative treatment and self administered treatment versus ablative treatment alone for external anogenital warts. External anogenital warts are proliferative lesions. Till now, there is no consensus on the standard treatment of external anogenital warts. The combination of ablative therapy and self-administered treatment has been reported to achieve sustained complete clearance than ablative therapy. The aim (...) of this review was to compare the efficacy on achieving complete clearance of warts between the combination of ablative therapy with self-administered therapy and ablative therapy alone.We conducted a systematic review to evaluate the efficacy and safety of the combination of ablative therapy and self-administered treatment for external anogenital warts. The Cochrane Central Register of Controlled Trials, Medline, Embase and Science Citation Index Expanded, China National Knowledge Infrastructure and Wanfang

2020 International Journal of Dermatology

2. Effectiveness of topical and ablative therapies in treatment of anogenital warts: a systematic review and network meta-analysis. (Full text)

Effectiveness of topical and ablative therapies in treatment of anogenital warts: a systematic review and network meta-analysis. To generate estimates of comparative clinical effectiveness for interventions used in the treatment of anogenital warts (AGWs) through the systematic review, appraisal and synthesis of data from randomised controlled trials (RCTs).Systematic review and network meta-analysis of RCTs. Search strategies were developed for MEDLINE, Embase, the Cochrane Library and the Web (...) of Science. For electronic databases, searches were run from inception to March 2018. The systematic review was carried out following the general principles recommended in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement.People aged ≥16 years with clinically diagnosed AGWs (irrespective of biopsy confirmation).Topical and ablative treatments recommended by the British Association for Sexual Health and HIV for the treatment of AGWs, either as monotherapy or in combination

2020 BMJ open PubMed abstract

3. Intralesional vitamin D3 injection in the treatment of warts: A systematic review and meta-analysis. (Full text)

Intralesional vitamin D3 injection in the treatment of warts: A systematic review and meta-analysis. 31678326 2020 03 16 1097-6787 82 4 2020 Apr Journal of the American Academy of Dermatology J. Am. Acad. Dermatol. Intralesional vitamin D3 injection in the treatment of warts: A systematic review and meta-analysis. 1013-1015 S0190-9622(19)32982-2 10.1016/j.jaad.2019.10.059 Chia-Han Yeh Marvin M Department of Dermatology, Wan Fang Hospital, Taipei Medical University, Taiwan. Tsai Tsung-Yu TY

2020 Journal of the American Academy of Dermatology PubMed abstract

4. Topically applied treatments for external genital warts in nonimmunocompromised patients: a systematic review and network meta-analysis. (Abstract)

Topically applied treatments for external genital warts in nonimmunocompromised patients: a systematic review and network meta-analysis. Selecting a topical treatment from among the numerous topical agents for external genital warts remains challenging without clear evidence. Our aim was to evaluate comparatively the efficacy and safety of topical agents for external genital warts using a network meta-analysis. We included all randomized controlled trials that evaluated any topically applied (...) treatment for external genital warts. Using the R package netmeta, network meta-analyses were performed with a frequentist approach. We identified 41 relevant studies comprising 6371 patients. Among conventional agents, podophyllotoxin 0·5% solution (odds ratio 1·94, 95% confidence interval 1·02-3·71) was significantly more efficacious than imiquimod 5% cream for lesion clearance; however, it was associated with a higher overall adverse event rate. Sinecatechins 15% ointment (odds ratio 0·21, 95

2020 The British journal of dermatology

5. The efficacy of diphencyprone immunotherapy for the treatment of cutaneous warts: a systematic review and meta-analysis. (Abstract)

The efficacy of diphencyprone immunotherapy for the treatment of cutaneous warts: a systematic review and meta-analysis. Background: Cutaneous warts, a common skin condition, may resolve spontaneously or become recalcitrant. Diphencyprone has been shown by many studies to have efficacy in treating warts, with varied results.Objectives: We aimed to perform a meta-analysis of the cure rate following the use of diphencyprone immunotherapy as a cutaneous wart treatment.Materials and methods (...) studies were included (6 prospective studies, 4 retrospective studies, 3 randomized controlled trials, and 1 case report), representing a total of 851 patients. The random-effects pooled efficacy for diphencyprone was 75.5% (95% CI, 64.6%-83.9%; I2 = 87%).Conclusions: Diphencyprone immunotherapy has a high efficacy to cure warts. This method may be used as an adjunctive modality for the treatment of warts in cases of conventional treatment failure.

2019 The Journal of dermatological treatment

6. Topical Cantharidin/ Salicylic Acid/ Podophyllin for the Treatment of Warts: Clinical Effectiveness and Guidelines

Topical Cantharidin/ Salicylic Acid/ Podophyllin for the Treatment of Warts: Clinical Effectiveness and Guidelines Topical Cantharidin/ Salicylic Acid/ Podophyllin for the Treatment of Warts: Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Topical Cantharidin/ Salicylic Acid/ Podophyllin for the Treatment of Warts: Clinical Effectiveness and Guidelines Topical Cantharidin/ Salicylic Acid/ Podophyllin for the Treatment of Warts: Clinical Effectiveness (...) and Guidelines Last updated: January 21, 2019 Project Number: RA1006-000 Product Line: Research Type: Drug Report Type: Reference List Result type: Report Question What is the comparative clinical effectiveness of topical cantharidin/salicylic acid/podophyllin versus other topical treatments for warts? What are the evidence-based guidelines for the topical treatment of warts? Key Message One non-randomized study and two evidence-based guidelines were identified regarding topical cantharidin/ salicylic acid

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

7. Oral cimetidine as the treatment of common warts

Oral cimetidine as the treatment of common warts Oral cimetidine as the treatment of common warts – Morsels of Evidence \t\t\t\r\n\t\t\t \t\t\t\r\n\t\t\t Share this: Like this: Like Loading... ","author":{"@type":"Person","name":"Michael Tam"},"image":["https:\/\/evidencebasedmedicine.com.au\/wp-content\/uploads\/2019\/01\/MO-DecJan2019cover.png"]} Toggle search form Toggle navigation Evidence-based medicine for general practitioners Jan 07 2019 Oral cimetidine as the treatment of common warts (...) By in , 7 January 2019 Journal reference: Yilmaz E, Alpsoy E, Basaran E. Cimetidine therapy for warts: a placebo-controlled, double-blind study. J Am Acad Dermatol 1996 Jun;34(6):1005-7 Link: Published: June 1996 Evidence cookie says… The limited research evidence does not support the use of oral cimetidine as the treatment of common warts anecdotal evidence of major benefits are not seen in blinded randomised trials although cimetidine is often seen as benign, side-effects were reported in a fifth

2019 Morsels of Evidence

8. Efficacy and Safety of Topical Cantharidin Treatment for Molluscum Contagiosum and Warts: A Systematic Review. (Abstract)

Efficacy and Safety of Topical Cantharidin Treatment for Molluscum Contagiosum and Warts: A Systematic Review. Topical cantharidin is routinely used for the treatment of molluscum contagiosum and warts. The objective of this systematic review is to assess the efficacy and safety of topical cantharidin treatment for molluscum contagiosum and warts.We performed a systematic review of studies assessing topical cantharidin treatment of molluscum contagiosum or warts. We searched the databases (...) was demonstrated with topical cantharidin alone. Topical cantharidin in combination with podophyllotoxin and salicylic acid demonstrated efficacy for plantar warts (pediatric and adult; clearance rate range 81-100%; four studies had 100% clearance), with the majority clearing after a single treatment. Satisfaction with cantharidin therapy was high, especially in molluscum contagiosum. Pain (7-85.7%), blistering (10-100%), and hyper-/hypopigmentation (1.8-53.3%) were the most commonly occurring adverse effects

2018 American journal of clinical dermatology

9. Intralesional Immunotherapy for the Treatment of Warts: A Network Meta-analysis. (Abstract)

Intralesional Immunotherapy for the Treatment of Warts: A Network Meta-analysis. Without clear evidence, selecting among the existing immunotherapeutic options for warts remains challenging.Through network meta-analyses, we aimed to evaluate the comparative efficacy of different intralesional immunotherapeutic modalities.We included randomized controlled trials comparing intralesional immunotherapeutic modalities to cryotherapy, placebo, or imiquimod. All outcomes were presented as odds ratios

2018 Journal of American Academy of Dermatology

10. Imiquimod for the Treatment of Genital Warts: A Review of Clinical Effectiveness and Cost-Effectiveness

Imiquimod for the Treatment of Genital Warts: A Review of Clinical Effectiveness and Cost-Effectiveness Imiquimod for the Treatment of Genital Warts: A Review of Clinical Effectiveness and Cost-Effectiveness | CADTH.ca Find the information you need Imiquimod for the Treatment of Genital Warts: A Review of Clinical Effectiveness and Cost-Effectiveness Imiquimod for the Treatment of Genital Warts: A Review of Clinical Effectiveness and Cost-Effectiveness Published on: September 25, 2017 Project (...) Number: RC0930-000 Product Line: Research Type: Drug Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of imiquimod for the treatment of genital warts? What is the cost-effectiveness of imiquimod for the treatment of genital warts? Key Message Evidence from systematic reviews with low quality included studies suggests that overall for patients with anogenital warts (AGW) compared to placebo, treatment with imiquimod (IMQ) is associated

2017 Canadian Agency for Drugs and Technologies in Health - Rapid Review

11. Adjuvant treatment of anogenital warts with systemic interferon: a systematic review and meta-analysis. (Full text)

Adjuvant treatment of anogenital warts with systemic interferon: a systematic review and meta-analysis. Interferons are natural messenger proteins that are used to treat various disease entities. Due to their immunomodulating, antiviral and antiproliferative effects, the systemic administration of interferons after ablative treatment for anogenital warts (AGWs) has been advocated to increase clearance and decrease recurrence rates. However, studies investigating the efficacy of adjuvant (...) of the evidence ranged from 'very low' to 'high'. The significantly higher efficacy of low-dose alpha-interferon compared with placebo was based on a single trial, and our confidence in the effect estimates rated as 'low'. Overall, we found no reliable evidence favouring the systemic use of interferon after ablative treatment of AGW.© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly

2017 Sexually transmitted infections PubMed abstract

12. Green tea leaf extract (Catephen) - cutaneous treatment of external genital and perianal warts (condylomata acuminata

Green tea leaf extract (Catephen) - cutaneous treatment of external genital and perianal warts (condylomata acuminata AWMSG SECRETARIAT ASSESSMENT REPORT Green tea leaf extract (Catephen ® ) 10% Ointment Reference number: 2739 FULL SUBMISSION This report has been prepared by the All Wales Therapeutics and Toxicology Centre (AWTTC), in collaboration with the Centre for Health Economics and Medicines Evaluation, Bangor University. Please direct any queries to AWTTC: All Wales Therapeutics (...) This assessment report is based on evidence submitted by Kora Healthcare 1 . 1.0 PRODUCT DETAILS Licensed indication under consideration Green tea leaf extract (Catephen ® ) for the cutaneous treatment of external genital and perianal warts (condylomata acuminata) in immunocompetent patients from the age of 18 years. Dosing Up to 250 mg Catephen ® ointment as total single dose, corresponding to about 0.5 cm of ointment strand to be applied three times per day to all external genital and perianal warts (750 mg

2016 All Wales Medicines Strategy Group

13. Clinical effectiveness and cost-effectiveness of interventions for the treatment of anogenital warts: systematic review and economic evaluation. (Full text)

Clinical effectiveness and cost-effectiveness of interventions for the treatment of anogenital warts: systematic review and economic evaluation. Typically occurring on the external genitalia, anogenital warts (AGWs) are benign epithelial skin lesions caused by human papillomavirus infection. AGWs are usually painless but can be unsightly and physically uncomfortable, and affected people might experience psychological distress. The evidence base on the clinical effectiveness and cost (...) -effectiveness of treatments for AGWs is limited.To systematically review the evidence on the clinical effectiveness of medical and surgical treatments for AGWs and to develop an economic model to estimate the cost-effectiveness of the treatments.Electronic databases (MEDLINE, MEDLINE In-Process & Other Non-Indexed Citations, EMBASE, The Cochrane Library databases and Web of Science) were searched from inception (or January 2000 for Web of Science) to September 2014. Bibliographies of relevant systematic

2016 Health technology assessment (Winchester, England) PubMed abstract

14. Green tea leaf extract (Veregen) - an aggressive topical treatment for anogenital warts

Green tea leaf extract (Veregen) - an aggressive topical treatment for anogenital warts Prescrire IN ENGLISH - Spotlight ''In the April issue of Prescrire International: Green tea leaf extract (Veregen°) - an aggressive topical treatment for anogenital warts'', 1 April 2015 {1} {1} {1} | | > > > In the April issue of Prescrire International: Green tea leaf extract (Veregen°) - an aggressive topical treatment for anogenital warts Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 (...) most recent :  |   |   |   |   |   |   |   |   |  Spotlight In the April issue of Prescrire International: Green tea leaf extract (Veregen°) - an aggressive topical treatment for anogenital warts FREE DOWNLOAD In this sample page from the New Products section: while drugs obtained from plants have the reputation of being innocuous, they sometimes provoke serious adverse effects. Full text available for free download. Summary

2015 Prescrire

15. Efficacy, safety and tolerability of green tea catechins in the treatment of external anogenital warts: a systematic review and meta-analysis. (Abstract)

Efficacy, safety and tolerability of green tea catechins in the treatment of external anogenital warts: a systematic review and meta-analysis. External anogenital warts (EGWs) are non-malignant skin tumours caused by human papillomavirus. They are one of the fastest growing sexually transmitted diseases. Current treatments are unsatisfactory. Green tea sinecatechin Polyphenon E ointment is a botanical extract from green tea leaves exhibiting anti-oxidant, anti-viral and anti-tumour (...) evaluating efficacy and safety of Polyphenon E 15% and 10% in the treatment of warts were included in the systematic review and meta-analysis. A total of 660 men and 587 women were enrolled. Regarding primary outcome, both Polyphenon E 15% and 10% demonstrated significantly higher likelihood of complete clearance of baseline and baseline and new warts compared with controls. No significant heterogeneity was detected. Recurrence rates were very low. Commonest local skin sign was erythema and local skin

2014 Journal of the European Academy of Dermatology and Venereology : JEADV

16. Imiquimod for the Treatment of External Genital Warts in Adults: Clinical and Cost-effectiveness

Imiquimod for the Treatment of External Genital Warts in Adults: Clinical and Cost-effectiveness Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources of the best evidence on the topic that CADTH could identify using all reasonable efforts within the time allowed. Rapid (...) of External Genital Warts in Adults: Clinical and Cost-effectiveness DATE: 07 December 2012 RESEARCH QUESTIONS 1. What is the clinical evidence of the benefits and harms of 5% imiquimod for the treatment of external genital warts? 2. What is the evidence of the cost-effectiveness of 5% imiquimod for the treatment of external genital warts KEY MESSAGE One systematic review, two meta-analyses, three randomized controlled trials, three non- randomized studies, and two economic evaluations were identified

2013 Canadian Agency for Drugs and Technologies in Health - Rapid Review

17. Randomised controlled trial: Cryotherapy for plantar warts more costly but no more effective than salicylic acid self-treatment

Randomised controlled trial: Cryotherapy for plantar warts more costly but no more effective than salicylic acid self-treatment Cryotherapy for plantar warts more costly but no more effective than salicylic acid self-treatment | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username (...) and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Cryotherapy for plantar warts more costly but no more effective than salicylic acid self-treatment Article Text Therapeutics Randomised controlled trial Cryotherapy

2012 Evidence-Based Medicine

18. Systemic treatments for cutaneous warts: a systematic review. (Abstract)

Systemic treatments for cutaneous warts: a systematic review. Systemic therapies are routinely used for the management of cutaneous warts. However, there is a lack of evidence-based data on their effectiveness.To assess the evidence for the efficacy of systemic treatments for cutaneous warts.We designed a systematic review of the randomized controlled clinical trials (1962 to April 2010) investigating systemic therapies for the treatment of cutaneous warts. We obtained data from MEDLINE, PubMed (...) , Current Contents, reference lists, and specialist textbooks, with no restriction on language. The main outcome measures were the total clearance of warts and the adverse effects.There was substantial heterogeneity in the design of the trials. No consistent evidence was found for the efficacy of cimetidine, levamisole or homeopathy, and only limited evidence was found for the efficacy of zinc.Reviewed trials of systemic treatments for cutaneous warts were highly variable in methods and quality

2012 Journal of Dermatological Treatment

19. Cryotherapy versus salicylic acid for the treatment of plantar warts (verrucae): a randomised controlled trial. (Full text)

Cryotherapy versus salicylic acid for the treatment of plantar warts (verrucae): a randomised controlled trial. To compare the clinical effectiveness of cryotherapy versus salicylic acid for the treatment of plantar warts.A multicentre, open, two arm randomised controlled trial.University podiatry school clinics, NHS podiatry clinics, and primary care in England, Scotland, and Ireland.240 patients aged 12 years and over, with a plantar wart that in the opinion of the healthcare professional (...) was suitable for treatment with both cryotherapy and salicylic acid.Cryotherapy with liquid nitrogen delivered by a healthcare professional, up to four treatments two to three weeks apart. Patient self treatment with 50% salicylic acid (Verrugon) daily up to a maximum of eight weeks.Complete clearance of all plantar warts at 12 weeks. Secondary outcomes were (a) complete clearance of all plantar warts at 12 weeks controlling for age, whether the wart had been treated previously, and type of wart, (b

2011 BMJ Controlled trial quality: predicted high PubMed abstract

20. Efficacy of topical treatments for cutaneous warts: a meta-analysis and pooled analysis of randomized controlled trials. (Full text)

Efficacy of topical treatments for cutaneous warts: a meta-analysis and pooled analysis of randomized controlled trials. Many topical treatments for cutaneous warts exist and previous reviews of trials did not follow intention-to-treat (ITT) principles for analysis. We aimed to perform a meta-analysis and pooled analysis of randomized controlled trials (RCTs) of topical treatment for cutaneous warts using ITT principles. Systematic electronic searches (Cochrane library, Medline, Embase (...) , Clinical trial registers) were conducted in May 2009. Included trials reported completed cure of warts and data were extracted from these trials. We performed random-effects meta-analysis and assessed heterogeneity using the I(2) statistic and conducted a pooled analysis of each treatment. We found 77 relevant studies of which the majority were of low methodological quality. Salicylic acid (SA) was superior to placebo with a risk ratio (RR) for cure of 1·60 [95% confidence interval (CI) 1·15-2·24

2011 The British journal of dermatology PubMed abstract