Topical NSAIDs versus Opioids for Acute Musculoskeletal Pain: A Review of the Clinical Effectiveness Topical NSAIDs versus Opioids for Acute Musculoskeletal Pain: A Review of the Clinical Effectiveness | CADTH.ca Find the information you need Topical NSAIDs versus Opioids for Acute Musculoskeletal Pain: A Review of the Clinical Effectiveness Topical NSAIDs versus Opioids for Acute Musculoskeletal Pain: A Review of the Clinical Effectiveness Published on: January 30, 2017 Project Number: RC0844 (...) -000 Product Line: Research Type: Drug Report Type: Summary with Critical Appraisal Result type: Report Question What is the comparative clinical effectiveness of topical NSAIDs versus opioids for the treatment of acute musculoskeletal pain? Key Message Compared with placebo, topical NSAIDs were effective in reducing pain from acute musculoskeletal conditions, such as sprains, strains or sport injuries. Adverse events were rare and were usually related to skin reactions. No evidence regarding

Topical NSAIDs

Can topical NSAIDs help relieve the pain of arthritis? Can topical NSAIDs help relieve the pain of arthritis? - Evidently Cochrane Search and hit Go By May 6, 2016 // A blog for non-medical readers by Lynda Ware, Senior Fellow in General Practice with Cochrane UK. “Just put some cream on it….” According to my three daughters, this was my stock response to any request they made for motherly intervention when pain struck. Whilst refuting this slur utterly (and the one about not even looking), I (...) might now point them in the direction of this updated review, which assesses the efficacy and safety of topical nonsteroidal anti-inflammatory drugs (NSAIDs), albeit in the context of chronic musculoskeletal pain rather than a bruised shin or finger. What’s more, I will point out that it’s likely that the carrier, to which the active drug is added, is pretty effective in its own right. Why is this important? Topical NSAIDs can act precisely where needed and without having to be absorbed via

Can topical NSAIDs help relieve the pain of arthritis? Can topical NSAIDs help relieve the pain of arthritis? - Evidently Cochrane Search and hit Go By May 6, 2016 // A blog for non-medical readers by Lynda Ware, Senior Fellow in General Practice with Cochrane UK. “Just put some cream on it….” According to my three daughters, this was my stock response to any request they made for motherly intervention when pain struck. Whilst refuting this slur utterly (and the one about not even looking), I (...) might now point them in the direction of this updated review, which assesses the efficacy and safety of topical nonsteroidal anti-inflammatory drugs (NSAIDs), albeit in the context of chronic musculoskeletal pain rather than a bruised shin or finger. What’s more, I will point out that it’s likely that the carrier, to which the active drug is added, is pretty effective in its own right. Why is this important? Topical NSAIDs can act precisely where needed and without having to be absorbed via

Topical NSAIDs for chronic musculoskeletal pain in adults. Use of topical nonsteroidal anti-inflammatory drugs (NSAIDs) to treat chronic musculoskeletal conditions has become widely accepted because they can provide pain relief without associated systemic adverse events. This review is an update of 'Topical NSAIDs for chronic musculoskeletal pain in adults', originally published in Issue 9, 2012.To review the evidence from randomised, double-blind, controlled trials on the efficacy and safety (...) of topically applied NSAIDs for chronic musculoskeletal pain in adults.We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, and our own in-house database; the date of the last search was February 2016. We also searched the references lists of included studies and reviews, and sought unpublished studies by asking personal contacts and searching online clinical trial registers and manufacturers' web sites.We included randomised, double-blind, active or inert carrier

Systematic review: Topical NSAIDs significantly reduces pain in adults with acute musculoskeletal injuries Topical NSAIDs significantly reduces pain in adults with acute musculoskeletal injuries | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts (...) OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Topical NSAIDs significantly reduces pain in adults with acute musculoskeletal injuries Article Text Therapeutics/Prevention Systematic review Topical NSAIDs significantly reduces pain in adults

Topical NSAIDs: good relief for acute musculoskeletal pain Topical NSAIDs: good relief for acute musculoskeletal pain - Evidently Cochrane Search and hit Go By June 25, 2015 // Non-steroidal anti-inflammatory drugs (NSAIDs) are routinely prescribed for mild to moderate pain and are the most commonly prescribed painkilling drugs worldwide. Taken by mouth or injected into a vein, the high concentrations of the drug throughout the body, necessary in order to work at the site of pain (...) and inflammation, can cause unpleasant or even serious side effects. Applied to the skin, so in a topical preparation such as a gel, cream or plaster, they can act where needed to relieve pain without affecting the rest of the body. For superficial painful conditions like sprains, strains and muscle soreness (and where the skin is unbroken) topical NSAIDs offer this clear advantage over taking tablets, as long as they work. How good are topical NSAIDs? A has been updated with new research confirming

Topical NSAIDs for acute musculoskeletal pain in adults. Use of topical NSAIDs to treat acute musculoskeletal conditions has become widely accepted because they can provide pain relief without associated systemic adverse events. This review is an update of 'Topical NSAIDs for acute pain in adults' originally published in Issue 6, 2010.To determine the efficacy and safety of topically applied NSAIDs in acute musculoskeletal pain in adults.We searched the Cochrane Register of Studies Online (...) particularly interested to compare different formulations (gel, cream, plaster) of individual NSAIDs.For this update we added 14 new included studies (3489 participants), and excluded four studies. We also identified 20 additional reports of completed or ongoing studies that have not been published in full. The earlier review included 47 studies.This update included 61 studies. Most compared topical NSAIDs in the form of a gel, spray, or cream with a similar topical placebo; 5311 participants were treated

Systematic review with meta-analysis: Topical NSAIDS provide effective pain relief for patients with hand or knee osteoarthritis with similar efficacy, and fewer side effects, than oral NSAIDS Topical NSAIDS provide effective pain relief for patients with hand or knee osteoarthritis with similar efficacy, and fewer side effects, than oral NSAIDS | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie (...) settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Topical NSAIDS provide effective pain

Should Topical NSAIDs Be Used to Treat Acute Musculoskeletal Conditions? SystematicReviewSnapshot ClinicalSynopsis TAKE-HOME MESSAGE Topical nonsteroidal anti-in?ammatory drugs effectively reduce pain associated with musculoskeletal conditions compared with placebo, with fewer adverse events compared with oral nonsteroidal anti-in?ammatory drugs. METHODS DATA SOURCES The authors searched the Cochrane Central Register of Controlled Trials (CENTRAL) (Cochrane Library, 2009, issue 4), MEDLINE (...) the list of those included in this review. 7 This Cochrane review demonstrated that topical non- steroidal anti-in?ammatory drugs, com- pared with placebo, provide adequate Performance of topical nonsteroidal anti-in?ammatory drugs versus placebo in acute musculoskeletal injuries. Studies (Total No. of Patients) Treatment Bene?t,* RR (95% CI) Adverse Event, † RR (95% CI) I 2 ,% Topical NSAID vs placebo 31 (3,462) 1.5 (1.4–1.6) 1.1 (0.88–1.4) 74 RR, Relative risk; CI, con?dence interval; NSAID

Cochrane systematic review: Topical NSAIDs provide effective relief of acute musculoskeletal pain compared to placebo, with no increase in risk of adverse effects Topical NSAIDs provide effective relief of acute musculoskeletal pain compared to placebo, with no increase in risk of adverse effects | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about (...) how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Topical NSAIDs provide effective relief of acute musculoskeletal pain compared to placebo

Influences on older people's decision making regarding choice of topical or oral NSAIDs for knee pain: qualitative study. To explore the factors that influence older people's decision making regarding use of topical or oral ibuprofen for their knee pain.Qualitative interview study nested within a randomised controlled trial and a patient preference study that compared advice to use oral or topical non-steroidal anti-inflammatory drugs (NSAIDs) for knee pain in older people.11 general practices (...) .30 people aged > or =50 with knee pain.Participants' decision making was influenced by their perceptions of the associated risk of adverse effects, presence of other illness, nature of their pain, advice received, and practicality. Although participants' understanding of how the medications worked was sometimes poor their decision making about the use of NSAIDs seemed logical and appropriate. Participants' model for treatment was to use topical NSAIDs for mild, local, and transient pain and oral

Review: topical NSAIDs reduce pain in osteoarthritis only during the first 2 weeks of use Review: topical NSAIDs reduce pain in osteoarthritis only during the first 2 weeks of use | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers (...) of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: topical NSAIDs reduce pain in osteoarthritis only during the first 2 weeks of use Article Text Treatment Review: topical NSAIDs reduce pain in osteoarthritis only during the first 2 weeks of use Free Cathy R