for this systematic review snapshot is: Wakai A, Lawrenson JG, Lawrenson AL, et al. Topical non-steroidal anti-inflammatory drugs for analgesia in traumatic corneal abrasions. Cochrane Database Syst Rev . 2017;5:CD009781. Jestin N. Carlson, MD, MS, and Alan Jones, MD, serve as editors of the SRS series. © 2018 by the American College of Emergency Physicians. Access this article on Visit ScienceDirect to see if you have access via your institution. Article Tools (100 minimum order) Article Related Video Article (...) Are Topical Nonsteroidal Anti-Inflammatory Drugs Useful for Analgesia in Patients With Traumatic Corneal Abrasions? Are Topical Nonsteroidal Anti-Inflammatory Drugs Useful for Analgesia in Patients With Traumatic Corneal Abrasions? - Annals of Emergency Medicine Email/Username: Password: Remember me Search Terms Search within Search Share this page Access provided by Volume 73, Issue 2, Pages 157–159 Are Topical Nonsteroidal Anti-Inflammatory Drugs Useful for Analgesia in Patients

the comparative clinical effectiveness of topical NSAIDs versus opioids could be identified. Tags anesthesia, administration, topical, anti-inflammatory agents, non-steroidal, musculoskeletal pain, musculoskeletal Files In Brief Published : June 28, 2017 Rapid Response Summary with Critical Appraisal Published : January 30, 2017 Related Content Follow us: © 2019 Canadian Agency for Drugs and Technologies in Health Get our newsletter: (...) -000 Product Line: Research Type: Drug Report Type: Summary with Critical Appraisal Result type: Report Question What is the comparative clinical effectiveness of topical NSAIDs versus opioids for the treatment of acute musculoskeletal pain? Key Message Compared with placebo, topical NSAIDs were effective in reducing pain from acute musculoskeletal conditions, such as sprains, strains or sport injuries. Adverse events were rare and were usually related to skin reactions. No evidence regarding

Topical NSAIDs

Systematic review: Topical NSAIDs significantly reduces pain in adults with acute musculoskeletal injuries Topical NSAIDs significantly reduces pain in adults with acute musculoskeletal injuries | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts (...) OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Topical NSAIDs significantly reduces pain in adults with acute musculoskeletal injuries Article Text Therapeutics/Prevention Systematic review Topical NSAIDs significantly reduces pain in adults

Topical NSAIDs: good relief for acute musculoskeletal pain Topical NSAIDs: good relief for acute musculoskeletal pain - Evidently Cochrane Search and hit Go By June 25, 2015 // Non-steroidal anti-inflammatory drugs (NSAIDs) are routinely prescribed for mild to moderate pain and are the most commonly prescribed painkilling drugs worldwide. Taken by mouth or injected into a vein, the high concentrations of the drug throughout the body, necessary in order to work at the site of pain (...) that topical NSAIDs are an effective and safe means of relieving acute musculoskeletal pain in adults. The new evidence also tells us much more than we knew before about which ones work best. The evidence comes from 61 randomized controlled trials (RCTs) with 8386 people. Several different topical NSAIDs were compared, mostly with placebo in the same carrier – so gel with a drug compared to the gel without a drug, for example. Both would be rubbed into the skin so we know that any effect is not just from

Systematic review with meta-analysis: Topical NSAIDS provide effective pain relief for patients with hand or knee osteoarthritis with similar efficacy, and fewer side effects, than oral NSAIDS Topical NSAIDS provide effective pain relief for patients with hand or knee osteoarthritis with similar efficacy, and fewer side effects, than oral NSAIDS | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie (...) settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Topical NSAIDS provide effective pain

the list of those included in this review. 7 This Cochrane review demonstrated that topical non- steroidal anti-in?ammatory drugs, com- pared with placebo, provide adequate Performance of topical nonsteroidal anti-in?ammatory drugs versus placebo in acute musculoskeletal injuries. Studies (Total No. of Patients) Treatment Bene?t,* RR (95% CI) Adverse Event, † RR (95% CI) I 2 ,% Topical NSAID vs placebo 31 (3,462) 1.5 (1.4–1.6) 1.1 (0.88–1.4) 74 RR, Relative risk; CI, con?dence interval; NSAID (...) topical salicylates were not in- cluded in this review because they are no longer classi?ed as topical nonsteroidal anti-in?ammatory drugs. Only patient-reported out- comes were included in this re- view and investigator-reported outcomes were not used. DATA EXTRACTION AND SYNTHESIS Quality of study methodology was assessed independently by 2 investiga- tors. Data comparing topical non- steroidal anti-in?ammatory drugs with placebo were analyzed with a ?xed-effects model and were ex- pressed

Cochrane systematic review: Topical NSAIDs provide effective relief of acute musculoskeletal pain compared to placebo, with no increase in risk of adverse effects Topical NSAIDs provide effective relief of acute musculoskeletal pain compared to placebo, with no increase in risk of adverse effects | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about (...) how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Topical NSAIDs provide effective relief of acute musculoskeletal pain compared to placebo

-steroidal anti-inflammatory drugs was safer than oral administration for osteoarthritis in older adults, but that many patients reported systemic adverse effects with topical agents. Reliance on a narrative synthesis, and some lack of reporting in the review process, means the reliability of these conclusions is unclear. Authors' objectives To systematically review literature on reported adverse effects associated with the use of topical non-steroidal anti-inflammatory drugs (NSAIDs) in older adults (...) with osteoarthritis. Searching MEDLINE (from 1950 to November 2009), Scopus, EMBASE, Web of Science, and the Cochrane Library were searched for relevant studies published in English. Search terms were reported. Abstracts from dissertations and American College of Rheumatology meetings were also searched. Bibliographies of reviews and individuals studies were scanned for further studies. Study selection Papers were excluded if they were obviously unrelated to topical non-steroidal anti-inflammatory drugs (NSAIDs

Influences on older people's decision making regarding choice of topical or oral NSAIDs for knee pain: qualitative study. To explore the factors that influence older people's decision making regarding use of topical or oral ibuprofen for their knee pain.Qualitative interview study nested within a randomised controlled trial and a patient preference study that compared advice to use oral or topical non-steroidal anti-inflammatory drugs (NSAIDs) for knee pain in older people.11 general practices (...) .30 people aged > or =50 with knee pain.Participants' decision making was influenced by their perceptions of the associated risk of adverse effects, presence of other illness, nature of their pain, advice received, and practicality. Although participants' understanding of how the medications worked was sometimes poor their decision making about the use of NSAIDs seemed logical and appropriate. Participants' model for treatment was to use topical NSAIDs for mild, local, and transient pain and oral

Kessenich , RN, DSN, ARNP Statistics from Altmetric.com Lin J, Zhang W, Jones A, et al . Efficacy of topical non-steroidal anti-inflammatory drugs in the treatment of osteoarthritis: meta-analysis of randomised controlled trials. BMJ 2004 ; 329 : 324 . Q Are topical non-steroidal anti-inflammatory drugs (NSAIDs) efficacious for treatment of osteoarthritis? METHODS Data sources: Medline, CINAHL, EMBASE/Excerpta Medica, Scientific Citation Index, and Cochrane Library (up to October 2003); reference lists (...) the first week but not during weeks 2–4 (table ). Topical NSAIDS did not differ from placebo for adverse events. View this table: Topical non-steroidal anti-inflammatory drugs (NSAIDs) v placebo or oral NSAIDs for osteoarthritis* Topical v oral NSAIDs . Topical NSAIDs were less effective than oral NSAIDs for pain reduction in the first week, but did not differ for weeks 2–4 (table ). Topical NSAIDs did not differ from oral NSAIDs for adverse events, gastrointestinal events, or withdrawals because

for knee OA. Funding Not stated. Bibliographic details Biswal S, Medhi B, Pandhi P. Longterm efficacy of topical nonsteroidal antiinflammatory drugs in knee osteoarthritis: metaanalysis of randomized placebo controlled clinical trials. Journal of Rheumatology 2006; 33(9): 1841-1844 PubMedID Indexing Status Subject indexing assigned by NLM MeSH Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal /administration & Arthralgia /epidemiology /prevention & Comorbidity; Humans; Incidence (...) The review assessed the long-term efficacy (at least 4 weeks) of topical therapies for pain control in primary knee osteoarthritis. The authors concluded that topical non-steroidal anti-inflammatory drugs (NSAIDs) provide effective pain relief for knee osteoarthritis. The authors caution against generalising to other NSAID preparations. The small data set on which the review was based, differences in treatment duration, uncertain study quality, and uncertainty about the statistical techniques used

Topical nonsteroidal anti-inflammatory drugs for corneal abrasions: meta-analysis of randomized trials Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.