Latest & greatest articles for Topical Corticosteroid

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Top results for Topical Corticosteroid

1. Topical Corticosteroids Improve Healing Time in Patients with Aphthous Ulcers

Topical Corticosteroids Improve Healing Time in Patients with Aphthous Ulcers UTCAT3273, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Topical Corticosteroids Improve Healing Time in Patients with Aphthous Ulcers Clinical Question In patients with aphthous ulcers, does treatment with topical corticosteroids, as compared to a placebo, improve healing time of the ulcers? Clinical Bottom Line Patients treated (...) with topical corticosteroids show an improved ulcer healing time. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Staines/2015 8 studies/583 patients Systematic review of randomized trials Key results 5 of the 8 studies in which ulcer duration was evaluated found that application of topical corticosteroids decreased the time required for the ulcer to heal (P Evidence Search “recurrent” AND “aphthous

2017 UTHSCSA Dental School CAT Library

2. Long-term management of moderate-to-severe atopic dermatitis with dupilumab and concomitant topical corticosteroids (LIBERTY AD CHRONOS): a 1-year, randomised, double-blinded, placebo-controlled, phase 3 trial. (PubMed)

Long-term management of moderate-to-severe atopic dermatitis with dupilumab and concomitant topical corticosteroids (LIBERTY AD CHRONOS): a 1-year, randomised, double-blinded, placebo-controlled, phase 3 trial. Dupilumab (an anti-interleukin-4-receptor-α monoclonal antibody) blocks signalling of interleukin 4 and interleukin 13, type 2/Th2 cytokines implicated in numerous allergic diseases ranging from asthma to atopic dermatitis. Previous 16-week monotherapy studies showed that dupilumab (...) substantially improved signs and symptoms of moderate-to-severe atopic dermatitis with acceptable safety, validating the crucial role of interleukin 4 and interleukin 13 in atopic dermatitis pathogenesis. We aimed to evaluate the long-term efficacy and safety of dupilumab with medium-potency topical corticosteroids versus placebo with topical corticosteroids in adults with moderate-to-severe atopic dermatitis.In this 1-year, randomised, double-blinded, placebo-controlled, phase 3 study (LIBERTY AD CHRONOS

2017 Lancet

4. Long-term topical corticosteroid use and risk of skin cancer: a systematic review protocol. (PubMed)

Long-term topical corticosteroid use and risk of skin cancer: a systematic review protocol. The objective of this systematic review is to synthesize the best available research evidence to determine the risk of skin cancer in patients on long-term use of topical corticosteroids. Specifically the review question is: In people using long-term (regular use over one month) topical corticosteroids, what is the risk of developing skin cancer (clinically or histologically confirmed basal cell

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2016 JBI database of systematic reviews and implementation reports

5. Psoriasis patients’ experiences concerning medical adherence to treatment with topical corticosteroids (PubMed)

Psoriasis patients’ experiences concerning medical adherence to treatment with topical corticosteroids Nonadherence to topical treatment of psoriasis is a common cause of treatment failure. This focus group study was conducted to obtain the patients' own experiences and explanations regarding medical adherence. The participants consisted of eight primary adherent patients with moderate psoriasis treated with corticosteroid or corticosteroid-calcipotriol combinations, purposefully sampled (...) in the prescriber, diverging information from health care personnel, experiencing side effects, having fear of side effects, impractical formulations of topical products, and impatience regarding time before an effect of the treatment was observed. From this study, the recommendations for the prescribing doctor to improve medical adherence are, the doctor needs to take time to listen to the patient, prescribe a topical product that is easy to apply and less greasy, inform the patients about benefits from

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2016 Psoriasis (Auckland, N.Z.)

6. Systematic review: Best evidence supports topical corticosteroids and routine saline irrigations for medical treatment of chronic rhinosinusitis

Systematic review: Best evidence supports topical corticosteroids and routine saline irrigations for medical treatment of chronic rhinosinusitis Best evidence supports topical corticosteroids and routine saline irrigations for medical treatment of chronic rhinosinusitis | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies (...) , please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Best evidence supports topical corticosteroids and routine saline irrigations for medical treatment of chronic

2016 Evidence-Based Medicine (Requires free registration)

7. Association of Topical Corticosteroid Use and Bone Mineral Density in Patients with Atopic Dermatitis

Association of Topical Corticosteroid Use and Bone Mineral Density in Patients with Atopic Dermatitis "Association of Topical Corticosteroid Use and Bone Mineral Density in " by Carsten Paulson < > > > > > Title Author Date of Graduation Summer 8-8-2015 Degree Type Capstone Project Degree Name Master of Science in Physician Assistant Studies First Advisor Annjanette Sommers, PA-C, MS Rights . Abstract Background Atopic dermatitis (AD) is a common pruritic inflammatory skin disease. First-line (...) therapy for AD involves the use of topical corticosteroids. With long-term use, these agents exert systemic effects and have been associated with adverse effects on bone health. This review assesses the current evidence for an association between topical corticosteroid use and bone mineral density in patients with atopic dermatitis. Methods An exhaustive search of available literature was conducted in using the MEDLINE-Ovid, Web of Science, CINAHL, and Evidence-Based Medicine Reviews Multifile

2015 Pacific University EBM Capstone Project

8. Corticosteroids - topical (skin), nose, and eyes

Corticosteroids - topical (skin), nose, and eyes Corticosteroids - topical (skin), nose, and eyes - NICE CKS Clinical Knowledge Summaries Share Corticosteroids - topical (skin), nose, and eyes: Summary Corticosteroids are synthetic analogues of the natural hormones that are produced by the adrenal cortex. Local corticosteroids are predominantly glucocorticoids. They have 4 main effects: Anti-inflammatory. Immunosuppressive. Anti-proliferative (anti-mitotic). Vasoconstrictive. Topical (...) , or infection. The length of treatment with topical corticosteroids depends on the diagnosis. Generally, very potent corticosteroids should not be used for more than 3 weeks continuously. If treatment is indicated for longer, intermittent dosing and gradual tapering of the dose should be considered, and more frequent monitoring for adverse effects should be arranged. Less potent topical corticosteroids can be used for up to 3 months, except in intertriginous areas, on the face and neck, or under occlusion

2015 NICE Clinical Knowledge Summaries

9. Topical corticosteroids as adjunctive therapy for bacterial keratitis. (PubMed)

Topical corticosteroids as adjunctive therapy for bacterial keratitis. Bacterial keratitis is a serious ocular infectious disease that can lead to severe visual disability. Risk factors for bacterial corneal infection include contact lens wear, ocular surface disease, corneal trauma, and previous ocular or eyelid surgery. Topical antibiotics constitute the mainstay of treatment in cases of bacterial keratitis, whereas the use of topical corticosteroids as an adjunctive therapy to antibiotics (...) remains controversial. Topical corticosteroids are usually used to control inflammation using the smallest amount of the drug. Their use requires optimal timing, concomitant antibiotics, and careful follow-up.The objective of the review was to assess the effectiveness and safety of corticosteroids as adjunctive therapy for bacterial keratitis. Secondary objectives included evaluation of health economic outcomes and quality of life outcomes.We searched CENTRAL (which contains the Cochrane Eyes

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2014 Cochrane

10. Topical corticosteroids for treating phimosis in boys. (PubMed)

Topical corticosteroids for treating phimosis in boys. Until recently, phimosis has been treated surgically by circumcision or prepuceplasty; however, recent reports of non-invasive treatment using topical corticosteroids applied for four to eight weeks have been favourable. The efficacy and safety of topical corticosteroids for treating phimosis in boys has not been previously systematically reviewed.We aimed to 1) compare the effectiveness of the use of topical corticosteroid ointment applied (...) to the distal stenotic portion of the prepuce in the resolution of phimosis in boys compared with the use of placebo or no treatment, and 2) determine the rate of partial resolution (improvement) of phimosis, rate of re-stenosis after initial resolution or improvement of phimosis, and the rate of adverse events of topical corticosteroid treatment in boys with phimosis.We searched the Cochrane Renal Group's Specialised Register through contact with the Trials' Search Co-ordinator using search terms relevant

2014 Cochrane

11. Topical corticosteroids effective for nasal polyps

Topical corticosteroids effective for nasal polyps Topical corticosteroids effective for nasal polyps | Cochrane Primary Care Trusted evidence. Informed decisions. Better health. Enter terms Topical corticosteroids effective for nasal polyps Cochrane Trusted evidence. Informed decisions. Better health. Copyright © 2019 The Cochrane Collaboration | | We use cookies to improve your experience on our site.

2013 Cochrane PEARLS

12. Safety of topical corticosteroids in pregnancy. (PubMed)

Safety of topical corticosteroids in pregnancy. Topical corticosteroids are the most frequently prescribed dermatological treatment and are frequently used by pregnant women with skin conditions. However, little is known about their safety in pregnancy.To assess the effects of topical corticosteroids on pregnancy outcomes.On 5th May 2009 we searched the Cochrane Skin Group Specialised Register, the Cochrane Pregnancy and Childbirth Group Specialised Register, CENTRAL (The Cochrane Library 2009 (...) , Issue 2), MEDLINE (from 2003), and EMBASE (from 2005). We searched LILACS, CINAHL, British Nursing Index, SCI-EXPANDED, BIOSIS Previews, Conference Papers Index, and Conference Proceedings Citation Index-Science from inception to May 2009. We scanned the bibliographies of the included studies, published reviews, and articles that had cited the included studies. Pharmaceutical companies that have introduced an original topical corticosteroid product were contacted.Randomised controlled trials

2009 Cochrane

13. Topical intranasal corticosteroids in 4-11 year old children with persistent bilateral otitis media with effusion in primary care: double blind randomised placebo controlled trial. (PubMed)

Topical intranasal corticosteroids in 4-11 year old children with persistent bilateral otitis media with effusion in primary care: double blind randomised placebo controlled trial. To determine the clinical effectiveness of topical intranasal corticosteroids in children with bilateral otitis media with effusion.Double blind randomised placebo controlled trial.76 Medical Research Council General Practice Research Framework practices throughout the United Kingdom, between 2004 and 2007.217 (...) ) at one month (primary end point), three months, and nine months; adverse events; three month diary symptoms. Results 41% (39/96) of the topical steroid group and 45% (44/98) of the placebo group were cured in one or both ears at one month (difference favouring placebo 4.3% (95% confidence interval -9.3% to 18.1%). Poisson regression was done with adjustment for four pre-specified covariates (clinical severity, P=0.003; atopy, P=0.67; age, P=0.92; season, P=0.71). The adjusted relative risk at one

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2009 BMJ

14. Topical corticosteroids as adjunctive therapy for bacterial keratitis. (PubMed)

Topical corticosteroids as adjunctive therapy for bacterial keratitis. Bacterial keratitis is a serious ocular infectious disease that can lead to severe visual disability. Risk factors for bacterial corneal infection include contact lens wear, ocular surface disease, corneal trauma and previous ocular or eyelid surgery. Topical antibiotics constitute the mainstay of treatment in cases of bacterial keratitis where as the use of topical corticosteroids remains controversial. Topical (...) , an online database of ongoing trials (www.clinicaltrials.gov), reference lists of included trials, earlier reviews and the American Academy of Ophthalmology guidelines. We also contacted experts to identify any unpublished and ongoing randomized trials.We included randomized controlled trials evaluating adjunctive therapy with topical corticosteroids in people with bacterial keratitis.Two review authors independently screened all the retrieved articles. Methodological quality of the one included trial

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2007 Cochrane

15. A cost-utility analysis of pimecrolimus vs. topical corticosteroids and emollients for the treatment of mild and moderate atopic eczema

A cost-utility analysis of pimecrolimus vs. topical corticosteroids and emollients for the treatment of mild and moderate atopic eczema A cost-utility analysis of pimecrolimus vs. topical corticosteroids and emollients for the treatment of mild and moderate atopic eczema A cost-utility analysis of pimecrolimus vs. topical corticosteroids and emollients for the treatment of mild and moderate atopic eczema Pitt M, Garside R, Stein K Record Status This is a critical abstract of an economic (...) evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of topical corticosteroids (TCS) as a first-line treatment followed by pimecrolimus as a second-line treatment, and pimecrolimus as a first-line treatment followed by TCS, in the treatment of mild and moderate atopic eczema. Type

2006 NHS Economic Evaluation Database.

16. Frequency of application of topical corticosteroids for atopic eczema (TA81)

Frequency of application of topical corticosteroids for atopic eczema (TA81) Overview | Frequency of application of topical corticosteroids for atopic eczema | Guidance | NICE Frequency of application of topical corticosteroids for atopic eczema Technology appraisal guidance [TA81] Published date: 25 August 2004 Share Guidance on using topical corticosteroids for people with atopic eczema. Guidance development process Is this guidance up to date? . We found nothing new that affects

2004 National Institute for Health and Clinical Excellence - Technology Appraisals

17. Frequency of application of topical corticosteroids for atopic eczema

Frequency of application of topical corticosteroids for atopic eczema Frequency of application of topical corticosteroids for atopic eczema Frequency of application of topical corticosteroids for atopic eczema National Institute for Clinical Excellence Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation National Institute for Clinical Excellence. Frequency (...) of application of topical corticosteroids for atopic eczema. London: National Institute for Health and Clinical Excellence (NICE). Technology Appraisal Guidance 81. 2004 Authors' objectives To provide guidance on the frequency of application of topical corticosteroids for atopic eczema. Authors' conclusions This appraisal relates to the frequency of application of topical corticosteroids in the treatment of atopic eczema. It does not include the use of topical agents that combine corticosteroids with other

2004 Health Technology Assessment (HTA) Database.

18. Clinical and cost-effectiveness of once-daily versus more frequent use of same potency topical corticosteroids for atopic eczema: a systematic review and economic evaluation

Clinical and cost-effectiveness of once-daily versus more frequent use of same potency topical corticosteroids for atopic eczema: a systematic review and economic evaluation Clinical and cost-effectiveness of once-daily versus more frequent use of same potency topical corticosteroids for atopic eczema: a systematic review and economic evaluation Clinical and cost-effectiveness of once-daily versus more frequent use of same potency topical corticosteroids for atopic eczema: a systematic review (...) and economic evaluation Green C, Colquitt J L, Kirby J, Davidson P, Payne E Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Green C, Colquitt J L, Kirby J, Davidson P, Payne E. Clinical and cost-effectiveness of once-daily versus more frequent use of same potency topical corticosteroids for atopic eczema: a systematic review and economic evaluation

2004 Health Technology Assessment (HTA) Database.

19. Cost-effectiveness analysis of tacrolimus ointment versus high-potency topical corticosteroids in adults with moderate to severe atopic dermatitis

Cost-effectiveness analysis of tacrolimus ointment versus high-potency topical corticosteroids in adults with moderate to severe atopic dermatitis Cost-effectiveness analysis of tacrolimus ointment versus high-potency topical corticosteroids in adults with moderate to severe atopic dermatitis Cost-effectiveness analysis of tacrolimus ointment versus high-potency topical corticosteroids in adults with moderate to severe atopic dermatitis Ellis C N, Drake L A, Prendergast M M, Abramovits W (...) , Boguniewicz M, Daniel C R, Lebwohl M, Paller A S, Stevens S R, Whitaker-Worth D L, Tong K B Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology High-potency topical corticosteroids (HPTCs) were compared with tacrolimus ointment

2003 NHS Economic Evaluation Database.

20. Treatment of atopic dermatitis and impact on quality of life: a review with emphasis on topical non-corticosteroids

Treatment of atopic dermatitis and impact on quality of life: a review with emphasis on topical non-corticosteroids Treatment of atopic dermatitis and impact on quality of life: a review with emphasis on topical non-corticosteroids Treatment of atopic dermatitis and impact on quality of life: a review with emphasis on topical non-corticosteroids Schiffner R, Schiffner-Rohe J, Landthaler M, Stolz W CRD summary This review assessed the impact on quality of life of different topically applicable (...) alternatives to corticosteroids for the treatment of atopic dermatitis (AD). The authors concluded that there are a clear lack of randomised controlled studies that have compared different treatments and their impact on quality of life in participants with AD. Although a number of biases might have been introduced into the review, these conclusions appear appropriate. Authors' objectives To assess the impact on quality of life (QoL) for topically applicable alternatives to corticosteroids in atopic

2003 DARE.