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SporotrichosisSporotrichosis - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search Sporotrichosis Last reviewed: February 2019 Last updated: March 2018 Summary Endemic mycosis with worldwide distribution caused by the dimorphic fungus Sporothrix schenckii . The vast majority of sporotrichosis infections are lymphocutaneous or fixed cutaneous forms, although osteoarticular, pulmonary, meningeal, and disseminated (...) sporotrichosis may occur, especially in patients with diabetes, alcoholism, AIDS, and haematological malignancies, but also in normal hosts. Lymphocutaneous sporotrichosis is caused by traumatic inoculation of the fungus into the skin and results in an initial nodular lesion that usually ulcerates, which is followed by ascending nodular lymphangitis. The definitive test for diagnosis of lymphocutaneous sporotrichosis is culture of the fungus from skin lesions. Because of their non-specific presentation
Ocular sporotrichosis: A frequently misdiagnosed cause of granulomatous conjunctivitis in epidemic areas Sporotrichosis is a subcutaneous mycosis caused by Sporothrix sp., a dimorphic fungus. Although the cutaneous form is the most frequent form, the ocular presentation has been increasingly diagnosed in epidemic areas. We describe three cases of ocular sporotrichosis with the involvement of the ocular adnexa due to autoinoculation without trauma with successful antifungal treatment.Patient 1 (...) evolution. Specimens were obtained from the lesions of the three patients, and the cultures were positive for Sporothrix sp. The three cases were diagnosed as ocular sporotrichosis and were successfully treated with itraconazole (200-400 mg/d). Two of the three patients developed sequelae such as conjunctival fibrosis and symblepharon.We emphasize the importance of the ophthalmologist being familiar with the diagnosis and management of this rare and frequently misdiagnosed form of sporotrichosis.
Oral potassium iodide for the treatment of sporotrichosis. Sporotrichosis is a subacute or chronic disease, usually affecting the skin caused by a dimorphic (existing in two forms), aerobic (oxygen requiring) fungus called Sporothrix schenckii. Oral potassium iodide is widely used for cutaneous sporotrichosis in clinical medicine with more and more reports published. However, the benefits and adverse reactions of these treatments have not yet been systematically reviewed.To assess the effects (...) for or against oral potassium iodide as a treatment for sporotrichosis. Further randomised double-blind placebo-controlled trials are needed to define the efficacy and acceptability of these interventions.