Latest & greatest articles for Skin Abscess

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on Skin Abscess or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on Skin Abscess and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for Skin Abscess

1. Systemic Antibiotics for the Treatment of Skin and Soft Tissue Abscesses: A Systematic Review and Meta-Analysis

Systemic Antibiotics for the Treatment of Skin and Soft Tissue Abscesses: A Systematic Review and Meta-Analysis Systemic Antibiotics for the Treatment of Skin and Soft Tissue Abscesses: A Systematic Review and Meta-Analysis Michael Gottlieb, MD*; Joshua M. DeMott, PharmD, MSc; Marilyn Hallock, MD, MS; Gary D. Peksa, PharmD *Corresponding Author. E-mail: michaelgottliebmd@gmail.com, Twitter: @MGottliebMD. Study objective: The addition of antibiotics to standard incision and drainage (...) /10.1016/j.annemergmed.2018.02.011 INTRODUCTION Background Skinandsofttissueinfectionsareacommonpresentation toboththe emergencydepartment(ED) and outpatient clinics, comprisingmorethan6 millionvisits each year in theUnited States. 1,2 Abscesses represent nearly halfof all cases and theoverall incidence isincreasing annually. 2-5 Although the standard clinical management of skin and soft tissue abscesses includes incision and drainage, the adjunctive use of systemic antibiotics remains controversial. 6

2018 Annals of Emergency Medicine Systematic Review Snapshots

2. Systemic Antibiotics for the Treatment of Skin and Soft Tissue Abscesses: A Systematic Review and Meta-Analysis

Systemic Antibiotics for the Treatment of Skin and Soft Tissue Abscesses: A Systematic Review and Meta-Analysis The addition of antibiotics to standard incision and drainage is controversial, with earlier studies demonstrating no significant benefit. However, 2 large, multicenter trials have recently been published that have challenged the previous literature. The goal of this review was to determine whether systemic antibiotics for abscesses after incision and drainage improve cure (...) 0.32, 95% CI 0.23 to 0.44), with a minimally increased risk of minor adverse events (risk difference 4.4%, 95% CI 1.0% to 7.8%; odds ratio 1.29, 95% CI 1.06 to 1.58).The use of systemic antibiotics for skin and soft tissue abscesses after incision and drainage resulted in an increased rate of clinical cure. Providers should consider the use of antibiotics while balancing the risk of adverse events.Copyright © 2018 American College of Emergency Physicians. Published by Elsevier Inc. All rights

2018 EvidenceUpdates

3. Antibiotics for uncomplicated skin abscesses: systematic review and network meta-analysis (PubMed)

Antibiotics for uncomplicated skin abscesses: systematic review and network meta-analysis To assess the impact of adjunctive antibiotic therapy on uncomplicated skin abscesses.Systematic review and network meta-analysis.Medline, Embase, the Cochrane Central Register of Controlled Trials and ClinicalTrials.gov.A BMJ Rapid Recommendation panel provided input on design, important outcomes and the interpretation of the results. Eligible randomised controlled trials (RCTs) included a comparison (...) of antibiotics against no antibiotics or a comparison of different antibiotics in patients with uncomplicated skin abscesses, and reported outcomes prespecified by the linked guideline panel.Reviewers independently screened abstracts and full texts for eligibility, assessed risk of bias and extracted data. We performed random-effects meta-analyses that compared antibiotics with no antibiotics, along with a limited number of prespecified subgroup hypotheses. We also performed network meta-analysis

Full Text available with Trip Pro

2018 EvidenceUpdates

4. A Placebo-Controlled Trial of Antibiotics for Smaller Skin Abscesses. (PubMed)

A Placebo-Controlled Trial of Antibiotics for Smaller Skin Abscesses. Uncomplicated skin abscesses are common, yet the appropriate management of the condition in the era of community-associated methicillin-resistant Staphylococcus aureus (MRSA) is unclear.We conducted a multicenter, prospective, double-blind trial involving outpatient adults and children. Patients were stratified according to the presence of a surgically drainable abscess, abscess size, the number of sites of skin infection (...) , and the presence of nonpurulent cellulitis. Participants with a skin abscess 5 cm or smaller in diameter were enrolled. After abscess incision and drainage, participants were randomly assigned to receive clindamycin, trimethoprim-sulfamethoxazole (TMP-SMX), or placebo for 10 days. The primary outcome was clinical cure 7 to 10 days after the end of treatment.We enrolled 786 participants: 505 (64.2%) were adults and 281 (35.8%) were children. A total of 448 (57.0%) of the participants were male. S. aureus

2017 NEJM

5. Trimethoprim?Sulfamethoxazole for Uncomplicated Skin Abscess

Trimethoprim?Sulfamethoxazole for Uncomplicated Skin Abscess BestBets: Trimethoprim–Sulfamethoxazole for Uncomplicated Skin Abscess Trimethoprim–Sulfamethoxazole for Uncomplicated Skin Abscess Report By: Reece Baker MD and Jason Seamon DO - Emergency Medicine Physicians Institution: Grand Rapids Medical Education Research Partners/Michigan State University Date Submitted: 30th May 2016 Date Completed: 11th February 2017 Last Modified: 11th February 2017 Status: Green (complete) Three Part (...) Question In [patients with uncomplicated skin abscesses who have undergone abscess incision and drainage], does [treatment with oral trimethoprim-sulfamethoxazole compared to placebo] [reduce treatment failure at 7 days]? Clinical Scenario A man aged 21 years presents to the ED with a 3-day history of increasing redness, swelling and pain in his right thigh. On examination there is an area of fluctuance, approximately 3 cm in diameter, with associated tenderness, on the right anterior thigh. Erythema

2017 BestBETS

8. Adjunctive antibiotics for drained skin abscesses improve clinical cure rate

Adjunctive antibiotics for drained skin abscesses improve clinical cure rate Adjunctive antibiotics for drained skin abscesses improve clinical cure rate | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts (...) Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Adjunctive antibiotics for drained skin abscesses improve clinical cure rate Article Text Commentary: General medicine Adjunctive antibiotics for drained skin abscesses improve clinical cure rate David A Talan Statistics from

2017 Evidence-Based Medicine (Requires free registration)

9. Trimethoprim-Sulfamethoxazole for Uncomplicated Skin Abscess. (PubMed)

Trimethoprim-Sulfamethoxazole for Uncomplicated Skin Abscess. 27468069 2016 08 02 2018 12 02 1533-4406 375 3 2016 07 21 The New England journal of medicine N. Engl. J. Med. Trimethoprim-Sulfamethoxazole for Uncomplicated Skin Abscess. 285-6 10.1056/NEJMc1605392 Talan David A DA Mower William R WR Krishnadasan Anusha A eng Letter Comment United States N Engl J Med 0255562 0028-4793 0 Anti-Bacterial Agents 8064-90-2 Trimethoprim, Sulfamethoxazole Drug Combination AIM IM N Engl J Med. 2016 Mar (...) 3;374(9):823-32 26962903 N Engl J Med. 2016 Jul 21;375(3):284 27468070 N Engl J Med. 2016 Jul 21;375(3):284-5 27468071 N Engl J Med. 2016 Jul 21;375(3):285 27468072 Abscess drug therapy Anti-Bacterial Agents therapeutic use Drainage Female Humans Male Skin Diseases, Bacterial drug therapy Trimethoprim, Sulfamethoxazole Drug Combination therapeutic use 2016 7 29 6 0 2016 7 29 6 0 2016 8 3 6 0 ppublish 27468069 10.1056/NEJMc1605392 10.1056/NEJMc1605392#SA4

Full Text available with Trip Pro

2016 NEJM

10. Trimethoprim-Sulfamethoxazole for Uncomplicated Skin Abscess. (PubMed)

Trimethoprim-Sulfamethoxazole for Uncomplicated Skin Abscess. 27468070 2016 08 02 2018 12 02 1533-4406 375 3 2016 07 21 The New England journal of medicine N. Engl. J. Med. Trimethoprim-Sulfamethoxazole for Uncomplicated Skin Abscess. 284 10.1056/NEJMc1605392 Spellberg Brad B LAC+USC Medical Center, Los Angeles, CA bspellberg@dhs.lacounty.gov. eng Letter Comment United States N Engl J Med 0255562 0028-4793 0 Anti-Bacterial Agents 8064-90-2 Trimethoprim, Sulfamethoxazole Drug Combination AIM IM (...) N Engl J Med. 2016 Mar 3;374(9):823-32 26962903 N Engl J Med. 2016 Jul 21;375(3):285-6 27468069 Abscess drug therapy Anti-Bacterial Agents therapeutic use Drainage Female Humans Male Skin Diseases, Bacterial drug therapy Trimethoprim, Sulfamethoxazole Drug Combination therapeutic use 2016 7 29 6 0 2016 7 29 6 0 2016 8 3 6 0 ppublish 27468070 10.1056/NEJMc1605392 10.1056/NEJMc1605392#SA1

Full Text available with Trip Pro

2016 NEJM

11. Trimethoprim-Sulfamethoxazole for Uncomplicated Skin Abscess. (PubMed)

Trimethoprim-Sulfamethoxazole for Uncomplicated Skin Abscess. 27468071 2016 08 02 2018 12 02 1533-4406 375 3 2016 07 21 The New England journal of medicine N. Engl. J. Med. Trimethoprim-Sulfamethoxazole for Uncomplicated Skin Abscess. 284-5 10.1056/NEJMc1605392 Leiner Steven S Mission Neighborhood Health Center, San Francisco, CA steven.leiner@gmail.com. eng Letter Comment United States N Engl J Med 0255562 0028-4793 0 Anti-Bacterial Agents 8064-90-2 Trimethoprim, Sulfamethoxazole Drug (...) Combination AIM IM N Engl J Med. 2016 Mar 3;374(9):823-32 26962903 N Engl J Med. 2016 Jul 21;375(3):285-6 27468069 Abscess drug therapy Anti-Bacterial Agents therapeutic use Drainage Female Humans Male Skin Diseases, Bacterial drug therapy Trimethoprim, Sulfamethoxazole Drug Combination therapeutic use 2016 7 29 6 0 2016 7 29 6 0 2016 8 3 6 0 ppublish 27468071 10.1056/NEJMc1605392 10.1056/NEJMc1605392#SA2

Full Text available with Trip Pro

2016 NEJM

12. Trimethoprim-Sulfamethoxazole for Uncomplicated Skin Abscess. (PubMed)

Trimethoprim-Sulfamethoxazole for Uncomplicated Skin Abscess. 27468072 2016 08 02 2018 12 02 1533-4406 375 3 2016 07 21 The New England journal of medicine N. Engl. J. Med. Trimethoprim-Sulfamethoxazole for Uncomplicated Skin Abscess. 285 10.1056/NEJMc1605392 Pollara Gabriele G University College London, London, United Kingdom g.pollara@ucl.ac.uk. Marks Michael M London School of Hygiene and Tropical Medicine, London, United Kingdom. eng Letter Comment United States N Engl J Med 0255562 0028 (...) -4793 0 Anti-Bacterial Agents 8064-90-2 Trimethoprim, Sulfamethoxazole Drug Combination AIM IM N Engl J Med. 2016 Mar 3;374(9):823-32 26962903 N Engl J Med. 2016 Jul 21;375(3):285-6 27468069 Abscess drug therapy Anti-Bacterial Agents therapeutic use Drainage Female Humans Male Skin Diseases, Bacterial drug therapy Trimethoprim, Sulfamethoxazole Drug Combination therapeutic use 2016 7 29 6 0 2016 7 29 6 0 2016 8 3 6 0 ppublish 27468072 10.1056/NEJMc1605392 10.1056/NEJMc1605392#SA3

Full Text available with Trip Pro

2016 NEJM

13. Skin Abscess. (PubMed)

Skin Abscess. 26962909 2016 03 15 2016 03 11 1533-4406 374 9 2016 Mar 03 The New England journal of medicine N. Engl. J. Med. CLINICAL DECISIONS. Skin Abscess. 882-4 10.1056/NEJMclde1600286 Wilbur MaryAnn B MB Daum Robert S RS Gold Howard S HS eng Journal Article United States N Engl J Med 0255562 0028-4793 0 Anti-Bacterial Agents 0 Drug Combinations 39295-60-8 trimethoprim, sulfadoxine drug combination 88463U4SM5 Sulfadoxine AN164J8Y0X Trimethoprim AIM IM Abscess drug therapy therapy Anti (...) -Bacterial Agents therapeutic use Combined Modality Therapy Drainage Drug Combinations Female Humans Skin Diseases, Bacterial drug therapy therapy Sulfadoxine therapeutic use Trimethoprim therapeutic use Young Adult 2016 3 11 6 0 2016 3 11 6 0 2016 3 16 6 0 ppublish 26962909 10.1056/NEJMclde1600286

2016 NEJM

14. Trimethoprim-Sulfamethoxazole Therapy Reduces Failure and Recurrence in Methicillin-Resistant Staphylococcus aureus Skin Abscesses after Surgical Drainage (PubMed)

Trimethoprim-Sulfamethoxazole Therapy Reduces Failure and Recurrence in Methicillin-Resistant Staphylococcus aureus Skin Abscesses after Surgical Drainage To determine whether a 3-day vs 10-day course of antibiotics after surgical drainage of skin abscesses is associated with different failure and recurrence rates.Patients age 3 months to 17 years seeking care at a pediatric emergency department with an uncomplicated skin abscess that required surgical drainage were randomized to receive 3 (...) difference 10.3%, 95% CI 0.8%-19.9%).Patients with MRSA skin abscesses are more likely to experience treatment failure and recurrent skin infection if given 3 rather than 10 days of trimethoprim-sulfamethoxazole after surgical drainage.ClinicalTrials.gov: NCT02024867.Copyright © 2016 Elsevier Inc. All rights reserved.

2016 EvidenceUpdates

15. The Massachusetts abscess rule: a clinical decision rule using ultrasound to identify methicillin-resistant Staphylococcus aureus in skin abscesses (PubMed)

The Massachusetts abscess rule: a clinical decision rule using ultrasound to identify methicillin-resistant Staphylococcus aureus in skin abscesses Treatment failure rates for incision and drainage (I&D) of skin abscesses have increased in recent years and may be attributable to an increased prevalence of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA). Previous authors have described sonographic features of abscesses, such as the presence of interstitial fluid (...) , characteristics of abscess debris, and depth of abscess cavity. It is possible that the sonographic features are associated with MRSA and can be used to predict the presence of MRSA. The authors describe a potential clinical decision rule (CDR) using sonographic images to predict the presence of CA-MRSA.This was a pilot CDR derivation study using databases from two emergency departments (EDs) of patients presenting to the ED with uncomplicated skin abscesses who underwent I&D and culture of the abscess

Full Text available with Trip Pro

2014 EvidenceUpdates

16. Management of community-associated methicillin-resistant Staphylococcus aureus skin abscesses in children

Management of community-associated methicillin-resistant Staphylococcus aureus skin abscesses in children Uncomplicated skin abscesses in previously well children are typically managed with drainage alone. An increasing percentage of such abscesses are due to methicillin-resistant Staphylococcus aureus infections. Although definitive data are lacking, drainage alone appears to be a reasonable strategy for methicillin-resistant S aureus skin abscesses, with antibiotics reserved for infants (...) younger than three months of age, or for children who are systemically unwell, have underlying medical problems or have significant surrounding cellulitis.  Key Words: Methicillin-resistant; Skin abscess; Staphylococcus aureus  

2011 Canadian Paediatric Society

17. Randomized controlled trial of trimethoprim-sulfamethoxazole for uncomplicated skin abscesses in patients at risk for community-associated methicillin-resistant Staphylococcus aureus infection (PubMed)

Randomized controlled trial of trimethoprim-sulfamethoxazole for uncomplicated skin abscesses in patients at risk for community-associated methicillin-resistant Staphylococcus aureus infection Community-associated methicillin-resistant Staphylococcus aureus is now the leading cause of uncomplicated skin abscesses in the United States, and the role of antibiotics is controversial. We evaluate whether trimethoprim-sulfamethoxazole reduces the rate of treatment failures during the 7 days after (...) incision and drainage and whether it reduces new lesion formation within 30 days.In this multicenter, double-blind, randomized, placebo-controlled trial, we randomized adults to oral trimethoprim-sulfamethoxazole or placebo after uncomplicated abscess incision and drainage. Using emergency department rechecks at 2 and 7 days and telephone follow-up, we assessed treatment failure within 7 days, and using clinical follow-up, telephone follow-up, and medical record review, we recorded the development

2010 EvidenceUpdates

18. Randomised controlled trial: Antibiotics provide no additional short-term benefit to surgical management of paediatric skin abscesses

Randomised controlled trial: Antibiotics provide no additional short-term benefit to surgical management of paediatric skin abscesses Antibiotics provide no additional short-term benefit to surgical management of paediatric skin abscesses | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Antibiotics provide no additional short-term benefit to surgical management of paediatric skin abscesses Article Text Therapeutics Randomised controlled

2010 Evidence-Based Medicine (Requires free registration)