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The screening and management of newborns at risk for low bloodglucose Hypoglycemia in the first hours to days after birth remains one of the most common conditions facing practitioners across Canada who care for newborns. Many cases represent normal physiologic transition to extrauterine life, but another group experiences hypoglycemia of longer duration. This statement addresses key issues for providers of neonatal care, including the definition of hypoglycemia, risk factors, screening (...) protocols, bloodglucose levels requiring intervention, and managing care for this condition. Screening, monitoring, and intervention protocols have been revised to better identify, manage, and treat infants who are at risk for persistent, recurrent, or severe hypoglycemia. The role of dextrose gels in raising glucose levels or preventing more persistent hypoglycemia, and precautions to reduce risk for recurrence after leaving hospital, are also addressed. This statement differentiates between
Techniques of monitoring bloodglucose during pregnancy for women with pre-existing diabetes. There are a number of ways of monitoring bloodglucose in women with diabetes during pregnancy, with self-monitoring of bloodglucose (SMBG) recommended as a key component of the management plan. No existing systematic reviews consider the benefits/effectiveness of different techniques of bloodglucose monitoring on maternal and infant outcomes among pregnant women with pre-existing diabetes (...) . The effectiveness of the various monitoring techniques is unclear. This review is an update of a review that was first published in 2014 and subsequently updated in 2017.To compare techniques of bloodglucose monitoring and their impact on maternal and infant outcomes among pregnant women with pre-existing diabetes.For this update, we searched Cochrane Pregnancy and Childbirth's Trials Register, ClinicalTrials.gov, the WHO International Clinical Trials Registry Platform (ICTRP) (1 November 2018), and reference
Perioperative Dietary Restriction of Carbohydrates in the Management of BloodGlucose Levels in Patients Undergoing Total Knee Replacement Approximately 75% of the US population over 65 years has prediabetes or diabetes. Despite current evidence for the efficacy of carbohydrate restriction in managing bloodglucose, this practice has not been implemented as part of routine perioperative bloodsugar management. We hypothesize that a carbohydrate reduced hospital diet (CRD) of 135 g/d may improve (...) bloodsugar levels following total knee arthroplasty (TKA) compared to a non-carbohydrate reduced hospital diet (NCRD).We randomized non-insulin-dependent prediabetic and diabetic patients undergoing TKA to either an NCRD or a CRD. Sixty-four patients were enrolled in the study and 2 were excluded, leading to 62 patients in the final analysis. The NCRD group included 14 females (47%) and 16 males (53%), with mean age of 68.5 years (±6.3 years). The CRD group included 16 females (50%) and 16 males
of structured SMBG testing. Enhanced usual care included quarterly clinic visits that focused specifically on diabetes management, free bloodglucose meters and strips, and office point-of-care A1c capability. The STG patients were given instruction on when to check their bloodsugar, how to interpret the results, and what meaningful lifestyle modifications to make based on the results. STG healthcare providers received training on how to interpret the 7-point daily glucose profiles and were provided (...) Blood on your hands: what’s the point of glucose self-monitoring in non-insulin treated diabetes? Blood On Your Hands: What’s The Point of Glucose Self-Monitoring in Non-Insulin Treated Diabetes? – Clinical Correlations Search Blood On Your Hands: What’s The Point of Glucose Self-Monitoring in Non-Insulin Treated Diabetes? March 26, 2019 6 min read By Gerardo Velez Peer Reviewed Mr. H is a 71-year-old patient with uncontrolled type 2 diabetes mellitus (T2DM) who came in for his routine follow
Prediction of individual life-years gained without cardiovascular events from lipid, blood pressure, glucose, and aspirin treatment based on data of more than 500 000 patients with Type 2 diabetes mellitus Although group-level effectiveness of lipid, blood pressure, glucose, and aspirin treatment for prevention of cardiovascular disease (CVD) has been proven by trials, important differences in absolute effectiveness exist between individuals. We aim to develop and validate a prediction tool (...) infarction, or stroke) and (ii) non-vascular mortality. Predictors were age, sex, smoking, systolic blood pressure, body mass index, haemoglobin A1c, estimated glomerular filtration rate, non- high-density lipoprotein cholesterol, albuminuria, T2DM duration, insulin treatment, and history of CVD. External validation was performed using data from the ADVANCE, ACCORD, ASCOT and ALLHAT-LLT-trials, the SMART and EPIC-NL cohorts, and the Scottish diabetes register (total n = 197 785). Predicted and observed
BloodSugar Regulation for Cardiovascular Health Promotion and Disease Prevention: JACC Health Promotion Series The primary objective of this study was to analyze the most up-to-date evidence regarding whether and how bloodsugar regulation influences cardiovascular health promotion and disease prevention by carrying out an umbrella review. Three separate, systematic literature searches identified 2,343 papers in total. Overall, 44 studies were included for data extraction and analysis (...) . The included systematic reviews and meta-analyses published between January 1, 2016, and December 31, 2017, were of good to very good quality (median Overview Quality Assessment Questionnaire score = 17). Identified evidence suggests that cardiovascular disease (CVD) prevention services should consider regulation of bloodglucose as a key target for intervention. Furthermore, the recommendations for effective intervention and service development/training described here for prevention of CVD should
Effect of self-acupressure on fasting bloodsugar (FBS) and insulin level in type 2 diabetes patients: a randomized clinical trial Uncontrolled symptoms of diabetes can lead to irreparable damage to vital organs. Despite the global trend towards the use of complementary alternative therapies, few studies have evaluated the effectiveness of self-acupressure in diabetes patients.The aim of this study was to determine the effect of self-acupressure on FBS and insulin level in type 2 diabetes (...) after treatment in the acupressure group (p=0.001). There were no significant differences between the levels of insulin in study or control groups. Serum FBS level decreased significantly after intervention in the acupressure group compared to the control group (p=0.02).Self-acupressure as a complementary alternative medicine can be a helpful complementary method in reducing FBS and increasing insulin levels in type 2 diabetic patients.This trial was registered at the Iranian Registry of Clinical
medications. HbA1c, fasting bloodglucose, and lipid profiles at 12 weeks were compared with baseline. In addition, the tolerability and side effects of SR2004 were recorded.One hundred and three patients completed 12 weeks of follow-up (87%) and were included in the results. At 12 weeks, HbA1c reduced from 9.0% to 7.1% (22%; p < 0.0001), mean bloodglucose decreased from 211 mg/dL to 133 mg/dL (37% reduction; p < 0.0001), mean total cholesterol to 185 mg/dL (13% reduction; p < 0.01) and mean serum (...) Study of the effect of the herbal composition SR2004 on hemoglobin A1c, fasting bloodglucose, and lipids in patients with type 2 diabetes mellitus Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by raised bloodglucose levels and peripheral insulin resistance. It is an increasingly prevalent global healthcare concern. Conventional treatment options are limited and in this context, there is renewed interest in evaluating the clinical and biological effects of traditional
The impact of intra-articular injection of diprospan at the knee joint on bloodglucose levels in diabetic patients To evaluate the effect of intra-articular (IA) corticosteroid injection (IACI) of betamethasone dipropionate/betamethasone sodium phosphate (Diprospan) on bloodglucose levels in diabetic patients METHODS: Patients with type 2 diabetes and symptomatic osteoarthritis of the knee (OAK) in whom medical therapy failed were administered 1 mL Diprospan IACI (5 mg of betamethasone (...) dipropionate +2 mg of betamethasone sodium phosphate). Patients were asked to monitor bloodglucose levels before and 2 h after meals for 1 week before and 12 days after the injection was administered. A control group was administered an IA injection of hyaluronic acid.Twelve patients from the Diprospan group and six from the control group were recruited for the study. Patients in the Diprospan group had significantly increased bloodglucose levels with median initial and peak levels of 187.5 mg% and 310
Mobile technology for self-monitoring of bloodglucose among patients with type 2 diabetes mellitus 29184899 2019 01 18 2306-9740 3 2017 mHealth Mhealth Mobile technology for self-monitoring of bloodglucose among patients with type 2 diabetes mellitus. 47 10.21037/mhealth.2017.10.03 Coughlin Steven S SS Department of Clinical and Digital Health Sciences, College of Allied Health Sciences, Augusta University, Augusta, GA, USA. Charlie Norwood Veterans Affairs Medical Center, Augusta, GA, USA
Effect of ertugliflozin on glucose control, body weight, blood pressure and bone density in type 2 diabetes mellitus inadequately controlled on metformin monotherapy (VERTIS MET) We evaluated the efficacy and safety of ertugliflozin, an SGLT2 inhibitor, in type 2 diabetes mellitus (T2DM) inadequately controlled (HbA1c, 7.0%-10.5%) with metformin monotherapy (≥1500 mg/d for ≥8 weeks).This was a double-blind, 26-week, multicentre study with ongoing 78-week extension (ClinicalTrials.gov identifier (...) : NCT02033889). A total of 621 participants were randomized 1:1:1 to placebo, or ertugliflozin 5 or 15 mg/d. The primary endpoint was change from baseline at week 26 in HbA1c. Secondary efficacy endpoints were change from baseline at week 26 in fasting plasma glucose (FPG), body weight, systolic/diastolic blood pressure (SBP/DBP) and number of participants with HbA1c <7.0% (53 mmol/mol). Pre-specified adverse events (AEs) of special interest and percent change from baseline in bone mineral density (BMD
Gestational Diabetes Mellitus and Frequency of BloodGlucose Monitoring: A Randomized Controlled Trial To assess whether testing bloodglucose four times daily compared with four times every other day would lead to similar birth weights among patients with gestational diabetes mellitus (GDM).This noninferiority randomized controlled trial was conducted at five centers. After receiving a diagnosis of GDM, women tested their bloodglucose every day for 7 days. After that period, compliant women (...) without hyperglycemia requiring treatment were randomized to either bloodglucose testing four times a day or every other day. Noninferiority would be declared if the mean birth weight in the every-other-day group was no higher than 165 g (5% difference assuming an average birth weight of 3,296 g) compared with the four times a day group. A total sample size of 286 women allowed noninferiority to be tested (one-sided .05 level of significance).From May 2013 to May 2016, of the 293 women with GDM who
A Team-Based Online Game Improves BloodGlucose Control in Veterans With Type 2 Diabetes: A Randomized, Controlled Trial Rigorous evidence is lacking whether online games can improve patients' longer-term health outcomes. We investigated whether an online team-based game delivering diabetes self-management education (DSME) to patients via e-mail or mobile application (app) can generate longer-term improvements in hemoglobin A1c (HbA1c).Patients (n = 456) on oral diabetes medications with HbA1c
Compliance to self-monitoring of bloodglucose among patients with type 2 diabetes mellitus and its influential factors: a real-world cross-sectional study based on the Tencent TDF-I bloodglucose monitoring platform To investigate the compliance to self-monitoring of bloodglucose (SMBG) among patients with type 2 diabetes mellitus (T2DM) and its influential factors.The real-world SMBG use over 90 days among 415 T2DM patients were recorded by using a bloodglucose monitoring platform (TDF-I
The impact of bloodglucose on community-acquired pneumonia: a retrospective cohort study Hyperglycaemia is common in patients with community-acquired pneumonia (CAP) and is a predictor of severe outcomes. Data are scarce regarding whether this association is affected by diabetes mellitus (DM) and also regarding its importance for severe outcomes in hospital. We determined the impact of bloodglucose on severe outcomes of CAP in hospital. We studied 1318 adult CAP patients hospitalised at three (...) Danish hospitals. The association between bloodglucose and DM status and severe clinical outcome (admission to an intensive care unit (ICU) and/or in-hospital mortality) was assessed by logistic regression. Models were adjusted for CURB-65 score and comorbidities. 12% of patients had DM. In patients without DM an increase in admission bloodglucose was associated with risk for ICU admittance (OR 1.25, 95% CI 1.13-1.39), but not significantly associated with in-hospital mortality (OR 1.10, 95% CI