Latest & greatest articles for Serum Ferritin

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Top results for Serum Ferritin

1. Investigation and management of a raised serum ferritin Full Text available with Trip Pro

or treatment (e.g. blood transfusion or iron infusion) that lead to a genuine increase in RES iron stores. Upper limit of the normal range for serum ferritin Most UK laboratories simply report 300–400 μg/l as the upper limit of normal for SF in adult males and 150–200 μg/l as the upper limit of normal for adult females (Association for Clinical Biochemistry, ; Worwood et al , ). There is however considerable variation in SF values in response to age, ethnic origin and sex. Mean SF values in neonates (...) , are outside the scope of this guideline, and readers are directed to the recently updated management guideline for this condition (Fitzsimons et al , ). Table 1. Causes of raised serum ferritin Increased ferritin synthesis due to iron accumulation Increase in ferritin synthesis not associated with significant iron accumulation Increased ferritin as a result of cellular damage Hereditary (genetic) haemochromatosis Hereditary acaeruloplasminaemia Secondary iron overload from blood transfusion or excessive

2018 British Committee for Standards in Haematology

2. Limitations of Serum Ferritin in Diagnosing Iron Deficiency in Inflammatory Conditions Full Text available with Trip Pro

Limitations of Serum Ferritin in Diagnosing Iron Deficiency in Inflammatory Conditions Patients with inflammatory conditions such as inflammatory bowel disease (IBD), chronic heart failure (CHF), and chronic kidney disease (CKD) have high rates of iron deficiency with adverse clinical consequences. Under normal circumstances, serum ferritin levels are a sensitive marker for iron status but ferritin is an acute-phase reactant that becomes elevated in response to inflammation, complicating (...) the diagnosis. Proinflammatory cytokines also trigger an increase in hepcidin, which restricts uptake of dietary iron and promotes sequestration of iron by ferritin within storage sites. Patients with inflammatory conditions may thus have restricted availability of iron for erythropoiesis and other cell functions due to increased hepcidin expression, despite normal or high levels of serum ferritin. The standard threshold for iron deficiency (<30 μg/L) therefore does not apply and transferrin saturation

2018 International journal of chronic diseases

3. Elevated Serum Ferritin Full Text available with Trip Pro

Elevated Serum Ferritin 25138336 2014 08 25 2018 11 13 1538-3598 312 7 2014 Aug 20 JAMA JAMA Elevated serum ferritin. 743-4 10.1001/jama.2014.302 VanWagner Lisa B LB Departments of Preventive Medicine and Medicine, Division of Gastroenterology & Hepatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois. Green Richard M RM Department of Medicine, Division of Gastroenterology & Hepatology, Section of Hepatology, Northwestern University Feinberg School of Medicine, Chicago (...) , Illinois. eng F32 HL116151 HL NHLBI NIH HHS United States 1F32HL116151-01 HL NHLBI NIH HHS United States Case Reports Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't United States JAMA 7501160 0098-7484 9007-73-2 Ferritins AIM IM JAMA. 2014 Dec 17;312(23):2572 25514310 JAMA. 2014 Dec 17;312(23):2572 25514312 Alcohol Drinking Arthritis, Reactive Biopsy Ferritins blood Hemochromatosis complications diagnosis genetics therapy Humans Liver pathology Male Middle Aged

2014 JAMA

4. Estimating Iron Overload in Patients with Suspected Liver Disease and Elevated Serum Ferritin (Abstract)

Estimating Iron Overload in Patients with Suspected Liver Disease and Elevated Serum Ferritin Iron status evaluation in patients with suspected liver disease and elevated serum ferritin is often challenging because hyperferritinemia does not always indicate iron overload. A reliable approach to estimate iron overload without exposing the patient to unnecessary investigations would help the clinician to identify patients who may take advantage of iron-removal therapy.We analyzed all liver (...) biopsies, including measurement of hepatic iron concentration, performed at the University Hospital Zurich from 1997 to 2010 to identify clinical and laboratory predictors of iron overload in patients with elevated serum ferritin (n = 147).Hyperferritinemia was predictive of iron overload only in patients with a high level of serum ferritin (>2000 μg/L). In patients with moderate hyperferritinemia, liver transaminases inversely correlated with hepatic iron concentration. A combination of both

2014 EvidenceUpdates

5. Effect of sodium iron ethylenediaminetetra-acetate (NaFeEDTA) on haemoglobin and serum ferritin in iron-deficient populations: a systematic review and meta-analysis of randomised and quasi-randomised controlled trials

Effect of sodium iron ethylenediaminetetra-acetate (NaFeEDTA) on haemoglobin and serum ferritin in iron-deficient populations: a systematic review and meta-analysis of randomised and quasi-randomised controlled trials Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2008 DARE.

6. Oral iron therapy reduced unexplained fatigue in non-anaemic women with serum ferritin concentrations 50 µg/l Full Text available with Trip Pro

Oral iron therapy reduced unexplained fatigue in non-anaemic women with serum ferritin concentrations 50 µg/l Oral iron therapy reduced unexplained fatigue in non-anaemic women with serum ferritin concentrations ⩽50 μg/l | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username (...) and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Oral iron therapy reduced unexplained fatigue in non-anaemic women with serum ferritin concentrations ⩽50 μg/l Article Text Therapeutics Oral iron therapy reduced

2005 Evidence-Based Medicine

7. Screening primary care patients for hereditary hemochromatosis with transferrin saturation and serum ferritin level: systematic review for the American College of Physicians

for practice or further research. Funding American College of Physicians. Bibliographic details Schmitt B, Golub R M, Green R. Screening primary care patients for hereditary hemochromatosis with transferrin saturation and serum ferritin level: systematic review for the American College of Physicians. Annals of Internal Medicine 2005; 143(7): 522-536 PubMedID Original Paper URL Indexing Status Subject indexing assigned by NLM MeSH Adult; Evidence-Based Medicine; Ferritins /blood; Genetic Testing (...) Screening primary care patients for hereditary hemochromatosis with transferrin saturation and serum ferritin level: systematic review for the American College of Physicians Screening primary care patients for hereditary hemochromatosis with transferrin saturation and serum ferritin level: systematic review for the American College of Physicians Screening primary care patients for hereditary hemochromatosis with transferrin saturation and serum ferritin level: systematic review for the American

2005 DARE.

8. Serum ferritin level predicts advanced hepatic fibrosis among U.S. patients with phenotypic hemochromatosis. (Abstract)

Serum ferritin level predicts advanced hepatic fibrosis among U.S. patients with phenotypic hemochromatosis. DNA-based HFE gene testing can confirm hereditary hemochromatosis in most people of Northern European descent. However, liver biopsy is important to detect cirrhosis.To develop noninvasive criteria to predict the presence or absence of advanced hepatic fibrosis or cirrhosis in Americans with hemochromatosis.Cross-sectional study.Six tertiary care referral clinics.182 patients (...) with phenotypically defined hemochromatosis.Liver histopathology and serum ferritin, aspartate aminotransferase, and alanine aminotransferase levels. Multivariate logistic regression analysis was used to examine factors associated with cirrhosis (defined as bridging fibrosis or unequivocal cirrhosis on biopsy).Cirrhosis was present in 40 of 182 (22%) patients in the overall group and in 35 of 147 (24%) of C282Y homozygotes. Only 1 of 93 patients with a serum ferritin level less than 1000 microg/L had cirrhosis

2003 Annals of Internal Medicine