Latest & greatest articles for Peripheral Neuropathy

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Top results for Peripheral Neuropathy

1. The effects of a supportive-educational intervention on women with type 2 diabetes and diabetic peripheral neuropathy: a randomized controlled trial

The effects of a supportive-educational intervention on women with type 2 diabetes and diabetic peripheral neuropathy: a randomized controlled trial The Effects of a Supportive-Educational Intervention on Women With Type 2 Diabetes and Diabetic Peripheral Neuropathy: A Randomized Controlled Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily (...) Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Clin Rehabil Actions . 2020 Jun;34(6):794-802. doi: 10.1177/0269215520914067. Epub 2020 Apr 20. The Effects of a Supportive-Educational Intervention on Women With Type 2 Diabetes and Diabetic Peripheral Neuropathy: A Randomized Controlled Trial , , , Affiliations Expand Affiliations 1 Bohlool Hospital, Gonabad University of Medical Sciences

2020 EvidenceUpdates

2. Serine and Lipid Metabolism in Macular Disease and Peripheral Neuropathy. (Abstract)

Serine and Lipid Metabolism in Macular Disease and Peripheral Neuropathy. Identifying mechanisms of diseases with complex inheritance patterns, such as macular telangiectasia type 2, is challenging. A link between macular telangiectasia type 2 and altered serine metabolism has been established previously.Through exome sequence analysis of a patient with macular telangiectasia type 2 and his family members, we identified a variant in SPTLC1 encoding a subunit of serine palmitoyltransferase (SPT (...) in mice led to increases in levels of retinal deoxysphingolipids and compromised visual function. Deoxysphingolipids caused photoreceptor-cell death in retinal organoids, but not in the presence of regulators of lipid metabolism.Elevated levels of atypical deoxysphingolipids, caused by variant SPTLC1 or SPTLC2 or by low serine levels, were risk factors for macular telangiectasia type 2, as well as for peripheral neuropathy. (Funded by the Lowy Medical Research Institute and others.).Copyright © 2019

2019 NEJM

3. Automated symptom and treatment side effect monitoring for improved quality of life among adults with diabetic peripheral neuropathy in primary care: a pragmatic, cluster, randomized, controlled trial Full Text available with Trip Pro

Automated symptom and treatment side effect monitoring for improved quality of life among adults with diabetic peripheral neuropathy in primary care: a pragmatic, cluster, randomized, controlled trial To evaluate the effectiveness of automated symptom and side effect monitoring on quality of life among individuals with symptomatic diabetic peripheral neuropathy.We conducted a pragmatic, cluster randomized controlled trial (July 2014 to July 2016) within a large healthcare system. We randomized (...) 1834 primary care physicians and prospectively recruited from their lists 1270 individuals with neuropathy who were newly prescribed medications for their symptoms. Intervention participants received automated telephone-based symptom and side effect monitoring with physician feedback over 6 months. The control group received usual care plus three non-interactive diabetes educational calls. Our primary outcomes were quality of life (EQ-5D) and select symptoms (e.g. pain) measured 4-8 weeks after

2019 EvidenceUpdates

4. Evaluation of combined radiofrequency and chemical blockade of multi-segmental lumbar sympathetic ganglia in painful diabetic peripheral neuropathy Full Text available with Trip Pro

Evaluation of combined radiofrequency and chemical blockade of multi-segmental lumbar sympathetic ganglia in painful diabetic peripheral neuropathy Painful diabetic peripheral neuropathy (PDPN) is one of the most common complications of diabetes. PDPN seriously affects the quality of life and is difficult to treat; therefore, there is an urgent need for new cost-effective treatment methods for PDPN.To investigate the efficacy and safety of radiofrequency thermocoagulation (RF) combined

2018 EvidenceUpdates Controlled trial quality: uncertain

5. Neuropad for detecting preclinical diabetic peripheral neuropathy

Neuropad for detecting preclinical diabetic peripheral neuropathy Neuropad for detecting preclinical Neuropad for detecting preclinical diabetic peripher diabetic peripheral neuropath al neuropathy y Medical technologies guidance Published: 10 September 2018 nice.org.uk/guidance/mtg38 © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Y Y our responsibility our responsibility This guidance represents the view of NICE (...) possible. Neuropad for detecting preclinical diabetic peripheral neuropathy (MTG38) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 2 of 14Contents Contents 1 Recommendations 4 2 The technology 5 Description of the technology 5 Current management 5 3 Evidence 7 Summary of clinical evidence 7 EAC's analysis of the clinical evidence 7 Summary of economic evidence 7 EAC's analysis of the economic evidence 8 4 Committee

2018 National Institute for Health and Clinical Excellence - Medical technologies

6. Effect of certain trimethoxy flavones on paclitaxel - induced peripheral neuropathy in mice Full Text available with Trip Pro

Effect of certain trimethoxy flavones on paclitaxel - induced peripheral neuropathy in mice The anti - nociceptive effect of 7, 2', 3' - trimethoxy flavone, 7, 2', 4' - trimethoxy flavone, 7, 3', 4' - trimethoxy flavone and 7, 5, 4' - trimethoxy flavone against inflammatory, neurogenic and thermal pain in mice was reported earlier. The present study was designed to investigate the effect of the above trimethoxy flavones in amelioration of peripheral neuropathy induced by paclitaxel.Peripheral (...) neuropathy was induced in mice by administration of a single i.p. dose (10 mg/kg) of paclitaxel. The manifestations of peripheral neuropathy such as tactile allodynia, cold allodynia and thermal hyperalgesia were assessed 24 h later by employing hair aesthesiometer test, acetone bubble test and hot water tail immersion test respectively. Further, the role of inflammatory cytokines like TNF - α, IL - 1β and free radicals in the action of trimethoxy flavones was investigated using in vitro assays.The test

2018 Integrative medicine research

7. Practice Advisory for the Prevention of Perioperative Peripheral Neuropathies Full Text available with Trip Pro

Practice Advisory for the Prevention of Perioperative Peripheral Neuropathies Practice Advisory for the Prevention of Perioperative Peripheral Neuropathies 2018:An Updated Report by the American Society of Anesthesiologists Task Force on Prevention of Perioperative Peripheral Neuropathies* | Anesthesiology | ASA Publications 4113640588 ASA Publications Log in to access full content You must be logged in to access this feature. ASA members enjoy complimentary access to ASA publications, as well (...) as a variety of educational resources. Non-ASA Members Login Free Practice Parameter | January 2018 Practice Advisory for the Prevention of Perioperative Peripheral Neuropathies 2018: An Updated Report by the American Society of Anesthesiologists Task Force on Prevention of Perioperative Peripheral Neuropathies* Author Notes This article is featured in “This Month in Anesthesiology,” page 1A. This article is featured in “This Month in Anesthesiology,” page 1A. Supplemental Digital Content is available

2018 American Society of Anesthesiologists

8. Lipid-lowering drugs (statins) and peripheral neuropathy Full Text available with Trip Pro

Lipid-lowering drugs (statins) and peripheral neuropathy Peripheral neuropathy is a disorder with often unknown causes. Some drugs, including statins, are proposed to be among the causes of peripheral neuropathy. This study aimed at evaluating this condition by electrodiagnostic study among patients who had received statins.This case-control study was conducted in Shiraz, Iran in 2015, and included 39 patients aged 35-55 who had received statins for at least 6 months, and 39 healthy matched (...) controls. Using electrodiagnosis, the sensory and motor wave features (amplitude, latency and nerve conduction velocity) of the peripheral nerves (Median, Ulnar, Tibial, Sural, and Peroneal) were evaluated among the subjects. Data were analyzed using SPSS software and p<0.05 was considered statistically significant.Regarding the occurrence of neuropathy, there were no significant differences in any of the definitions presented for peripheral neuropathy. However, the difference was close to significance

2018 Electronic physician

9. Tiny Tips: “TREADMILLS” Peripheral Neuropathy mnemonic

Tiny Tips: “TREADMILLS” Peripheral Neuropathy mnemonic Tiny Tips: “TREADMILLS” Peripheral Neuropathy mnemonic - CanadiEM Tiny Tips: “TREADMILLS” Peripheral Neuropathy mnemonic In , by Sean Patrick February 20, 2018 Peripheral neuropathy is prevalent in up to 2.4% of the general population 1 . It is often characterized by an asymmetric distribution with sensory symptoms following a dermatomal pattern. Initial investigations include a complete blood count (CBC), metabolic panel (electrolytes (...) , glucose, urea, creatinine), and thyroid stimulating hormone (TSH) 2 . There are many causes for peripheral neuropathy, so when considering the etiology, think “TREADMILLS.” T oxins Ethanol, Heavy metals, Tetanus, Organophosphates, Diphtheria R enal Failure E ndocrine Diabetes, Hypothyroidism A cquired Immunodeficiency Syndrome (AIDS) D rugs/ D eficiency Amiodarone, Procainamide, Digoxin, Hydralazine, Statins, Isoniazid, Chloroquine, Misoprostol, Metronidazole, Nitrofurantoin Vitamin B6 deficiency

2018 CandiEM

10. Peripheral Neuropathy Full Text available with Trip Pro

Peripheral Neuropathy Peripheral Neuropathy | ONS Hello [ Name ] ! Renew Membership: Hello [ Name ] ! Renew Membership: Menu Search Peripheral Neuropathy Peripheral neuropathy refers to neurologic dysfunction that occurs outside of the brain and spinal cord. Patients with cancer are at risk for , treatment, or both. Solid tumors can cause neuropathic symptoms and pain by pressing on local nerves. Chemotherapeutic agents that can cause peripheral neuropathy include epothilones, platinum analogs (...) , taxanes, and vinca alkaloids. Among patients treated with anticancer therapies known to increase the risk of peripheral neuropathy, 10%–100% will develop the condition. According to the research, peripheral neuropathy can cause pain and other sensory symptoms as well as patient safety concerns because of changes in dexterity, gait and balance problems, weakness, proprioception, and loss of some motor skills. This topic was updated on May 10, 2017. Likely to Be Effective Effectiveness Not Established

2017 Oncology Nursing Society Putting Evidence into Practice (PEP)

11. Prevention of Plantar Ulcers in People With Diabetic Peripheral Neuropathy Using Pressure-Sensing Shoe Insoles

Prevention of Plantar Ulcers in People With Diabetic Peripheral Neuropathy Using Pressure-Sensing Shoe Insoles Prevention of Plantar Ulcers in People With Diabetic Peripheral Neuropathy Using Pressure-Sensing Shoe Insoles | CADTH.ca CADTH Document Viewer Prevention of Plantar Ulcers in People With Diabetic Peripheral Neuropathy Using Pressure-Sensing Shoe Insoles Table of Contents Search this document Prevention of Plantar Ulcers in People With Diabetic Peripheral Neuropathy Using Pressure (...) -Sensing Shoe Insoles June 2017 Summary The SurroSense Rx system is a set of pressure-sensing shoe insoles that connect wirelessly to a proprietary smartwatch and is intended for people with diabetes who have mild to moderate sensory loss associated with diabetic peripheral neuropathy, or nerve damage. By providing real-time alerts about plantar pressure distributions, or the area of pressure between the foot and the surface supporting it, users of the SurroSense Rx system can alter their activities

2017 CADTH - Issues in Emerging Health Technologies

12. Prevention of Plantar Ulcers in People With Diabetic Peripheral Neuropathy Using Pressure-Sensing Shoe Insoles

Prevention of Plantar Ulcers in People With Diabetic Peripheral Neuropathy Using Pressure-Sensing Shoe Insoles Prevention of Plantar Ulcers in People With Diabetic Peripheral Neuropathy Using Pressure-Sensing Shoe Insoles | CADTH.ca CADTH Document Viewer Prevention of Plantar Ulcers in People With Diabetic Peripheral Neuropathy Using Pressure-Sensing Shoe Insoles Table of Contents Search this document Prevention of Plantar Ulcers in People With Diabetic Peripheral Neuropathy Using Pressure (...) -Sensing Shoe Insoles June 2017 Summary The SurroSense Rx system is a set of pressure-sensing shoe insoles that connect wirelessly to a proprietary smartwatch and is intended for people with diabetes who have mild to moderate sensory loss associated with diabetic peripheral neuropathy, or nerve damage. By providing real-time alerts about plantar pressure distributions, or the area of pressure between the foot and the surface supporting it, users of the SurroSense Rx system can alter their activities

2017 CADTH - Issues in Emerging Health Technologies

13. Preventing complications and treating symptoms of diabetic peripheral neuropathy

Preventing complications and treating symptoms of diabetic peripheral neuropathy Preventing complications and treating symptoms of diabetic peripheral neuropathy Preventing complications and treating symptoms of diabetic peripheral neuropathy Dy SM, Bennett WL, Sharma R, Zhang A, Waldfogel JM, Nesbit SA, Yeh H, Chelladurai Y, Feldman D, Wilson LM, Robinson KA Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment (...) has been made for the HTA database. Citation Dy SM, Bennett WL, Sharma R, Zhang A, Waldfogel JM, Nesbit SA, Yeh H, Chelladurai Y, Feldman D, Wilson LM, Robinson KA. Preventing complications and treating symptoms of diabetic peripheral neuropathy. Rockville: Agency for Healthcare Research and Quality (AHRQ). Comparative Effectiveness Review No. 187. 2017 Authors' objectives To assess benefits and harms of interventions for preventing diabetic peripheral neuropathy (DPN) complications and treatment

2017 Health Technology Assessment (HTA) Database.

16. Complex and Simple Clinical Reaction Times Are Associated with Gait, Balance, and Major Fall Injury in Older Subjects with Diabetic Peripheral Neuropathy Full Text available with Trip Pro

Complex and Simple Clinical Reaction Times Are Associated with Gait, Balance, and Major Fall Injury in Older Subjects with Diabetic Peripheral Neuropathy The aim of this work was to identify relationships between complex and simple clinical measures of reaction time (RTclin) and indicators of balance in older subjects with and without diabetic peripheral neuropathy (DPN).Prospective cohort design. Complex RTclin accuracy, simple RTclin latency, and their ratio were determined using a novel

2017 American journal of physical medicine & rehabilitation

17. Magnetic resonance neurography to study peripheral neuropathies

Magnetic resonance neurography to study peripheral neuropathies Magnetic resonance neurography to study peripheral neuropathies Magnetic resonance neurography to study peripheral neuropathies Brito V, Ciapponi A, Pichon-Riviere A, Augustovski F, García Martí S, Alcaraz A, Bardach A, López A, Rey-Ares L Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA (...) database. Citation Brito V, Ciapponi A, Pichon-Riviere A, Augustovski F, García Martí S, Alcaraz A, Bardach A, López A, Rey-Ares L. Magnetic resonance neurography to study peripheral neuropathies. Buenos Aires: Institute for Clinical Effectiveness and Health Policy (IECS). Informe de Respuesta Rapida No. 497. 2016 Authors' conclusions There is no evidence having shown clinical benefits with the inclusion of magnetic resonance neurography as a diagnostic tool in neuropathies, plexopathies

2016 Health Technology Assessment (HTA) Database.

18. An asymptomatic mutation complicating severe chemotherapy-induced peripheral neuropathy (CIPN): a case for personalised medicine and a zebrafish model of CIPN Full Text available with Trip Pro

An asymptomatic mutation complicating severe chemotherapy-induced peripheral neuropathy (CIPN): a case for personalised medicine and a zebrafish model of CIPN Targeted next-generation sequencing (NGS) identified a novel loss of function mutation in GARS, a gene linked to Charcot-Marie-Tooth disease (CMT), in a paediatric acute lymphoblastic leukaemia patient with severe chemotherapy-induced peripheral neuropathy (CIPN) due to vincristine. The patient was clinically asymptomatic, and lacked (...) a family history of neuropathy. The effect of the mutation was modelled in a zebrafish knockdown system that recapitulated the symptoms of the patient both prior to and after treatment with vincristine. Confocal microscopy of pre- and post-synaptic markers revealed that the GARS knockdown results in changes to peripheral motor neurons, acetylcholine receptors and their co-localisation in neuromuscular junctions (NMJs), whereas a sensitive and reproducible stimulus-response assay demonstrated

2016 NPJ genomic medicine

19. Survey of the management of chemotherapy-induced peripheral neuropathy in Japan: Japanese Society of Medical Oncology Full Text available with Trip Pro

Survey of the management of chemotherapy-induced peripheral neuropathy in Japan: Japanese Society of Medical Oncology Various drugs are administered for the management of chemotherapy-induced peripheral neuropathy (CIPN) in Japan. However, there have been no surveys undertaken to identify these drugs or their frequency of prescription. Therefore, we administered a questionnaire survey to the diplomates of the Subspecialty Board of Japanese Society of Medical Oncology (JSMO) to investigate

2016 ESMO open

20. Pregabalin in Patients With Painful Diabetic Peripheral Neuropathy Using an NSAID for Other Pain Conditions: A Double-Blind Crossover Study (Abstract)

Pregabalin in Patients With Painful Diabetic Peripheral Neuropathy Using an NSAID for Other Pain Conditions: A Double-Blind Crossover Study To evaluate pregabalin's efficacy and safety versus placebo to reduce pain in patients with diabetic peripheral neuropathy (DPN) using a concomitant nonsteroidal anti-inflammatory drug.In a randomized, double-masked, 14-week, 2-period, crossover study, patients with painful DPN using a nonsteroidal anti-inflammatory drug for non-DPN-related pain received

2016 EvidenceUpdates Controlled trial quality: predicted high