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Latest & greatest articles for Perianal Streptococcal Dermatitis
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Randomized, comparative efficacy trial of oral penicillin versus cefuroxime for perianalstreptococcaldermatitis in children To investigate the efficacy of penicillin compared with cefuroxime for group A beta-hemolytic Streptococcus pyogenes (GABHS) perianal dermatitis.Children 1 to 16 years of age with signs and symptoms of perianaldermatitis and a positive anal swab were randomized to penicillin or cefuroxime treatment and were clinically re-evaluated on day 3 and at the end of treatment (...) with the ethics committee. Clinical improvement was more rapid in the cefuroxime group (P = .028) and GAHBS was not isolated from the anus the last day of therapy in 13 of 14 patients treated with cefuroxime compared with 7 of 15 patients treated with penicillin (P < .01).Cefuroxime was more effective than penicillin and therefore should be considered as the treatment of choice for perianaldermatitis due to GABHS.