Paracervical Block for Intrauterine Device Placement Among Nulliparous Women: A Randomized Controlled Trial To investigate whether a 20-mL buffered 1% lidocaine paracervical block decreases pain during intrauterine device (IUD) placement.In a randomized, single-blind, placebo-controlled trial, women were assigned to receive either a 20-mL buffered 1% lidocaine paracervical block or no block before IUD placement. The primary outcome was pain with IUD placement measured on a 100-mm visual analog (...) scale. Our sample size had 80% power (α=0.05) to detect a 20-mm difference in visual analog scale scores with a SD of 28 mm. Secondary outcomes included pain with speculum placement, paracervical block administration, tenaculum placement, 5 minutes postprocedure, and overall pain perception.From October 7, 2014, through October 26, 2017, 64 women were enrolled and analyzed (33 in the paracervical block arm, 31 in the no-block arm). There were no differences in baseline demographics between

Paracervical Block for Laminaria Insertion Before Second-Trimester Abortion: A Randomized Controlled Trial To evaluate the efficacy of a paracervical block to decrease pain during osmotic dilator insertion before second-trimester abortion.In this double-blind, randomized trial, 41 women undergoing Laminaria insertion before a second-trimester abortion received either a paracervical block with 18 mL 1% lidocaine and 2 mL sodium bicarbonate or a sham block. Women were between 14 and 23 6/7 weeks (...) of gestation. The primary outcome was pain immediately after insertion of Laminaria. Women assessed their pain on a 100-mm visual analog scale. Secondary outcomes included assessment of pain at other times during the insertion procedure and overall satisfaction with pain control. To detect a 25-mm difference in pain immediately after Laminaria insertion, at an α of 0.05 and 80% power, we aimed to enroll 20 patients in each arm.From May 2015 to December 2015, 20 women received a paracervical block and 21

Paracervical block efficacy in office hysteroscopic sterilization: a randomized controlled trial To estimate the efficacy of paracervical block compared with saline for pain relief during office hysteroscopic sterilization.This study was a randomized, placebo-controlled study of women desiring hysteroscopic sterilization. A paracervical block of 1% lidocaine or normal saline was administered before office hysteroscopic sterilization. Patients and investigators were blinded to assignments. A pre (...) to procedural time (P=.047) and to group assignment (P<.01).Paracervical block with 1% lidocaine provides effective pain relief for cervical manipulations during office hysteroscopic sterilization, but does not reduce the pain associated with upper uterine/tubal manipulation when placing the devices.ClinicalTrials.gov, www.clinicaltrials.gov, NCT00811187.I.

Paracervical block with combined ketorolac and lidocaine in first-trimester surgical abortion: a randomized controlled trial To study the effects of a paracervical block with combined ketorolac and lidocaine on perceived pain during first-trimester surgical abortion.A double-masked, placebo-controlled, randomized clinical trial of 50 women undergoing first-trimester surgical abortions (before 11 weeks of gestation) received either oral ibuprofen with a lidocaine-alone paracervical block (...) or an oral placebo and paracervical block with combined ketorolac and lidocaine. Women completed a series of 100-mm visual analog scales (anchors: 0=none, 100 mm=worst imaginable) to measure their perceived pain (anticipated pain, pain during and after surgical abortion, and total satisfaction).Twenty-five women received preoperative oral ibuprofen followed by paracervical block with lidocaine alone, and 25 received oral placebo followed by paracervical block with combined ketorolac and lidocaine. Groups

Is it cost-effective to use a mucosal or paracervical block to relieve the pain and cramping from cryosurgery? A decision model Is it cost-effective to use a mucosal or paracervical block to relieve the pain and cramping from cryosurgery? A decision model Is it cost-effective to use a mucosal or paracervical block to relieve the pain and cramping from cryosurgery? A decision model Harper D M, Cobb J L Record Status This is a critical abstract of an economic evaluation that meets the criteria (...) for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of paracervical and mucosal blocks to relieve pain and cramping in 5-minute double-freeze cryosurgery for cervical intraepithelial neoplasia. Type of intervention Treatment. Economic study type Cost-effectiveness analysis. Study population The study population consisted