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Latest & greatest articles for Obesity Medication
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Association of Bariatric Surgery vs MedicalObesity Treatment With Long-term Medical Complications and Obesity-Related Comorbidities. The association of bariatric surgery and specialized medicalobesity treatment with beneficial and detrimental outcomes remains uncertain.To compare changes in obesity-related comorbidities in patients with severe obesity (body mass index ≥40 or ≥35 and at least 1 comorbidity) undergoing bariatric surgery or specialized medical treatment.Cohort study (...) with baseline data of exposures from November 2005 through July 2010 and follow-up data from 2006 until death or through December 2015 at a tertiary care outpatient center, Vestfold Hospital Trust, Norway. Consecutive treatment-seeking adult patients (n = 2109) with severe obesity assessed (221 patients excluded and 1888 patients included).Bariatric surgery (n = 932, 92% gastric bypass) or specialized medical treatment (n = 956) including individual or group-based lifestyle intervention programs.Primary
A Medically Supervised Pregnancy Exercise Intervention in Obese Women: A Randomized Controlled Trial To evaluate whether an intensive, medically supervised exercise intervention improved maternal glycemia and gestational weight gain in obese pregnant women when compared with routine prenatal care.This randomized controlled trial compared a medically supervised exercise intervention with routine prenatal care. The primary outcome was a reduction in mean maternal fasting plasma glucose (...) of gestation, excessive gestational weight gain greater than 9.1 kg was lower in the exercise group, 23.5% compared with 45.2% in the control group (P<.05).An intensive, medically supervised exercise intervention for obese women from early pregnancy did not improve maternal glycemia. Pregnant women who are obese, however, should be advised to exercise because it attenuates excessive gestational weight gain.International Standard Randomised Controlled Trials (ISRCTN) registry, ISRCTN 31045925.
The Perceptions of Medical School Students and Faculty Toward Obesity Medicine Education: Survey and Needs Analysis Recent trends in obesity show that over two-thirds of US adults are considered at least overweight (body mass index, BMI≥25 kg/m2) and of those, about one-third are categorized as obese (BMI≥30 kg/m2). Physicians can address the health impacts of obesity; yet research has suggested that physicians-in-training frequently fail to recognize obesity, are not properly educated (...) regarding treatment options, and spend relatively little clinic time treating obesity. Medical school is a unique opportunity to address this area of need so that the doctors of tomorrow are prepared to treat obesity appropriately.The objective of this study was to determine perceptions of where clinical training for medical students on the topic of obesity and its treatment should improve and expand so that we could address the needs identified in a computerized clinical simulation.We conducted
A Randomized, Controlled Multisite Study of Behavioral Interventions for Veterans with Mental Illness and Antipsychotic Medication-Associated Obesity Weight gain and other metabolic sequelae of antipsychotic medications can lead to medication non-adherence, reduced quality of life, increased costs, and premature mortality. Of the approaches to address this, behavioral interventions are less invasive, cost less, and can result in sustained long-term benefits.We investigated behavioral weight (...) management interventions for veterans with mental illness across four medical centers within the Veterans Affairs (VA) Healthcare System.We conducted a 12-month, multi-site extension of our previous randomized, controlled study, comparing treatment and control groups.Veterans (and some non-veteran women) diagnosed with mental illness, overweight (defined as having a BMI over 25), and required ongoing antipsychotic therapy.One group received "Lifestyle Balance" (LB; modified from the Diabetes Prevention
American Association of Clinical Endocrinologists and American College of Endocrinology Clinical Practice Guidelines for Comprehensive Medical Care of Patients with Obesity ENDOCRINE PRACTICE Vol 22 (Suppl 3) July 2016 1 AACE/ACE Guidelines AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY COMPREHENSIVE CLINICAL PRACTICE GUIDELINES FOR MEDICAL CARE OF PATIENTS WITH OBESITY W. Timothy Garvey, MD, FACE 1 ; Jeffrey I. Mechanick, MD, FACP , FACE, FACN, ECNU 2 (...) ; Elise M. Brett, MD, FACE, CNSC, ECNU 3 ; Alan J. Garber, MD, PhD, FACE 4 ; Daniel L. Hurley, MD, FACE 5 ; Ania M. Jastreboff, MD, PhD 6 ; Karl Nadolsky, DO 7 ; Rachel Pessah-Pollack, MD 8 ; Raymond Plodkowski, MD 9 ; and Reviewers of the AACE/ACE Obesity Clinical Practice Guidelines* American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice are systematically devel- oped statements to assist health care professionals in medical decision-making for specific clinical
Obesitymedications reduce total body weight by 3-9% compared with placebo, when combined with lifestyle changes. 24842056 2015 05 21 2018 12 02 1468-9618 18 1 2015 Jan Evidence-based nursing Evid Based Nurs Obesitymedications reduce total body weight by 3-9% compared with placebo, when combined with lifestyle changes. 29-30 10.1136/eb-2014-101785 Gadde Kishore M KM Duke University Medical Center, Durham, North Carolina, USA. Yancy William S WS Jr Duke University Medical Center, Durham, North (...) Carolina, USA Veterans Affairs Medical Center, Durham, North Carolina, USA. eng Journal Article Comment 2014 05 19 England Evid Based Nurs 9815947 1367-6539 0 Anti-Obesity Agents IM N JAMA. 2014 Jan 1;311(1):74-86 24231879 Anti-Obesity Agents therapeutic use Humans Life Style Obesity drug therapy Clinical Pharmacology Nutrition & Dietetics 2014 5 21 6 0 2014 5 21 6 0 2015 5 23 6 0 ppublish 24842056 eb-2014-101785 10.1136/eb-2014-101785
Surgical Versus Medical Treatment of Type 2 Diabetes Mellitus in Nonseverely Obese Patients: A Systematic Review and Meta-Analysis To compare surgical versus medical treatment of type 2 diabetes mellitus (T2DM) remission and comorbidities in patients with a body mass index (BMI) less than 35 kg/m2.Obesity surgery can achieve remission of T2DM and its comorbidities. Metabolic surgery has been proposed as a treatment option for diabetic patients with BMI less than 35 kg/m2 but the efficacy (...) of metabolic surgery has not been conclusively determined.A systematic literature search identified randomized (RCT) and nonrandomized comparative observational clinical studies (OCS) evaluating surgical versus medical T2DM treatment in patients with BMI less than 35 kg/m2. The primary outcome was T2DM remission. Additional analyses comprised glycemic control, BMI, HbA1c level, remission of comorbidities, and safety. Random effects meta-analyses were calculated and presented as weighted odds ratio
Corpulence and correspondence: president william h. Taft and the medical management of obesity. This article analyzes the letters exchanged as part of the clinical weight management of President William H. Taft, one of the first public figures in U.S. history to be defined popularly in terms of his pathologic obesity. In 1905, Taft hired Dr. Nathaniel E. Yorke-Davies, an English diet expert, to supervise a weight-loss plan. Taft corresponded extensively with Yorke-Davies over the next 10 years (...) , receiving and responding to courses of treatment via post. This correspondence is one of the few archival collections documenting physician and patient perspectives on the treatment of obesity, and it took place at the precise moment when obesity began to be framed as both a serious and medically manageable condition. This intimate clinical history of the 27th president and 10th chief justice of the Supreme Court offers a unique opportunity to examine in detail the history of the obesity experience
Metabolic Effects of Bariatric Surgery in Patients With Moderate Obesity and Type 2 Diabetes: Analysis of a randomized control trial comparing surgery with intensive medical treatment To evaluate the effects of two bariatric procedures versus intensive medical therapy (IMT) on β-cell function and body composition.This was a prospective, randomized, controlled trial of 60 subjects with uncontrolled type 2 diabetes (HbA1c 9.7 ± 1%) and moderate obesity (BMI 36 ± 2 kg/m(2)) randomized to IMT alone (...) with truncal fat and prandial free fatty acid levels.Bariatric surgery provides durable glycemic control compared with intensive medical therapy at 2 years. Despite similar weight loss as sleeve gastrectomy, gastric bypass uniquely restores pancreatic β-cell function and reduces truncal fat, thus reversing the core defects in diabetes.
Surgery or Medical Therapy for Obese Patients with Type 2 Diabetes? 22449318 2012 04 27 2018 12 01 1533-4406 366 17 2012 Apr 26 The New England journal of medicine N. Engl. J. Med. Surgery or medical therapy for obese patients with type 2 diabetes? 1635-6 10.1056/NEJMe1202443 Zimmet Paul P Alberti K George M M KG eng Editorial Comment 2012 03 26 United States N Engl J Med 0255562 0028-4793 0 Hypoglycemic Agents AIM IM N Engl J Med. 2012 Apr 26;366(17):1567-76 22449319 N Engl J Med. 2012 Apr (...) 26;366(17):1577-85 22449317 Biliopancreatic Diversion Diabetes Mellitus, Type 2 drug therapy surgery Female Gastrectomy Gastric Bypass Humans Hypoglycemic Agents therapeutic use Male Obesity surgery Obesity, Morbid surgery 2012 3 28 6 0 2012 3 28 6 0 2012 4 28 6 0 ppublish 22449318 10.1056/NEJMe1202443
Bariatric surgery versus intensive medical therapy in obese patients with diabetes. Observational studies have shown improvement in patients with type 2 diabetes mellitus after bariatric surgery.In this randomized, nonblinded, single-center trial, we evaluated the efficacy of intensive medical therapy alone versus medical therapy plus Roux-en-Y gastric bypass or sleeve gastrectomy in 150 obese patients with uncontrolled type 2 diabetes. The mean (±SD) age of the patients was 49±8 years, and 66 (...) decreased significantly after both surgical procedures but increased in patients receiving medical therapy only. The index for homeostasis model assessment of insulin resistance (HOMA-IR) improved significantly after bariatric surgery. Four patients underwent reoperation. There were no deaths or life-threatening complications.In obese patients with uncontrolled type 2 diabetes, 12 months of medical therapy plus bariatric surgery achieved glycemic control in significantly more patients than medical
Obesity: Inequalities in EBM, medical research and policy Obesity: Inequalities in EBM, medical research and policy | TrustTheEvidence.net Syndicate Discover the truth behind the research findings that affect everyday healthcare. » » Links Tags HONcode Certified This site complies with the for trustworthy health information: . Obesity: Inequalities in EBM, medical research and policy Ami Banerjee Last edited 26th August 2011 Today’s main news story is that and will continue to rise (...) Bookmark 'Obesity: Inequalities in EBM, medical research and policy' Navigator Search this site: Twitter TrustTheEvidence.net Search the TRIP Database Recent blog posts Top Ten Blog Articles Recent Comments 4 years 22 weeks ago 5 years 38 weeks ago 5 years 41 weeks ago 6 years 34 weeks ago 6 years 34 weeks ago 6 years 46 weeks ago 6 years 51 weeks ago 7 years 18 weeks ago 7 years 18 weeks ago 7 years 23 weeks ago Blog Archive (5) (5) (4) (4) (6) (6) (5) (4) (6) (8) (5) (4) (3) (5) (4) (6) (7) (4) (4
The Effectiveness of Roux-en-Y Bariatric Surgery Technique on Weight Loss and Diabetic Medication Reduction in Type 2 Morbidly Obese Adults Compared to Other Methods "The Effectiveness of Roux-en-Y Bariatric Surgery Technique on Weight L" by Audrea R. Williams < > > > > > Title Author Date of Graduation 8-15-2009 Degree Type Capstone Project Degree Name Master of Science in Physician Assistant Studies First Advisor Mark Pedemonte, MD Second Advisor Rob Rosenow PharmD, OD Third Advisor (...) . Hypothesis: Roux-en-Y gastric bypass surgery provides a more effective approach to morbid obesity and Type 2 Diabetes. Study Design: Exhaustive search of available medical literature. Methods: Literature search of CINAHL, PubMed, Ovid, Google Scholar, EJournals and search terms Roux-en-y, bariatric surgery, diabetes, surgery for obesity. Results: The studies reviewed confirmed that Roux-en-Y gastric bypass provides significant improvement in weight loss and modification of Type 2 Diabetes. Conclusion
Obesity subtypes and risk of spontaneous versus medically indicated preterm births in singletons and twins Using data from the Missouri maternally linked files (1989-1997), the authors examined the association among maternal obesity, obesity subtypes, and spontaneous and medically indicated preterm (<37 weeks) and very preterm (<33 weeks) births in singletons and twins. Adjusted odds ratios were obtained with correction for intracluster correlation. The prevalence of obesity increased by 77 (...) % greater odds of medically indicated preterm (odds ratio = 1.46, 95% confidence interval: 1.39, 1.54) and very preterm (odds ratio = 1.49, 95% confidence interval: 1.34, 1.65) births, and the risk increases with ascending severity of obesity (p(trend) < 0.01). For extreme obesity, the risk of medically indicated preterm and very preterm births was almost double that for nonobese women. Similar findings were observed in twins. These data suggest that obesity increases the risk for medically indicated
Risk of venous thromboembolism and efficacy of thromboprophylaxis in hospitalized obesemedical patients and in obese patients undergoing bariatric surgery. BACKGROUND: Obesity is considered a highly prevalent risk factor for venous thromboembolism (VTE) in hospitalized patients. However, recommendations for VTE prophylaxis in obese patients are not clear. METHODS: To evaluate obesity as a risk factor for VTE in medical and bariatric patients and the efficacy of VTE prophylaxis, we performed (...) a systematic review in MEDLINE, Cochrane Database of Systematic Reviews and LILACS from 1976 to 2006. Evidence was evaluated independently by 2 authors and presented descriptively. RESULTS: Of the 124 studies found, 87 were excluded based on predefined criteria. There is no consensus among studies, but prospective cohorts show that obesity is associated with a higher risk of VTE in medical patients. There is evidence that the risk of VTE exceeds that attributable to the surgical procedure alone
Risk of venous thromboembolism and efficacy of thromboprophylaxis in hospitalized obesemedical patients and in obese patients undergoing bariatric surgery Risk of venous thromboembolism and efficacy of thromboprophylaxis in hospitalized obesemedical patients and in obese patients undergoing bariatric surgery Risk of venous thromboembolism and efficacy of thromboprophylaxis in hospitalized obesemedical patients and in obese patients undergoing bariatric surgery Rocha A T, De Vasconcellos A G (...) in hospitalised obesemedical patients and obese patients undergoing bariatric surgery. Searching MEDLINE (1976 to May 2006), Cochrane Database of Systematic Reviews (2005) and LILACS (1985 to 2005) were searched for studies in English, Portuguese, Spanish, Italian and French; the search terms were reported. The reference lists of retrieved studies were also checked. Study selection Study designs of evaluations included in the review Randomised controlled trials (RCTs), and cohort and case-control studies