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Systematic review of scoliosis treatment among individuals living with myelomeningocele or spina bifida in Asia Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files
The Management of Myelomeningocele Study: full cohort 30-month pediatric outcomes Previous reports from the Management of Myelomeningocele Study demonstrated that prenatal repair of myelomeningocele reduces hindbrain herniation and the need for cerebrospinal fluid shunting, and improves motor function in children with myelomeningocele. The trial was stopped for efficacy after 183 patients were randomized, but 30-month outcomes were only available at the time of initial publication in 134 mother (...) -child dyads. Data from the complete cohort for the 30-month outcomes are presented here. Maternal and 12-month neurodevelopmental outcomes for the full cohort were reported previously.The purpose of this study is to report the 30-month outcomes for the full cohort of patients randomized to either prenatal or postnatal repair of myelomeningocele in the original Management of Myelomeningocele Study.Eligible women were randomly assigned to undergo standard postnatal repair or prenatal repair <26 weeks
Maternal?Fetal Surgery for Myelomeningocele Maternal–Fetal Surgery for Myelomeningocele - ACOG Menu ▼ Maternal–Fetal Surgery for Myelomeningocele Page Navigation ▼ Number 720, September 2017 (Replaces Committee Opinion Number 550, January 2013) Committee on Obstetric Practice Society for Maternal–Fetal Medicine The North American Fetal Therapy Network endorses this document. This Committee Opinion was developed by the American College of Obstetricians and Gynecologists’ Committee on Obstetric (...) direct, special, indirect, or consequential damages, incurred in connection with this publication or reliance on the information presented. Maternal–Fetal Surgery for Myelomeningocele ABSTRACT: Myelomeningocele, a severe form of spina bifida, occurs in approximately 1 in 3,000 live births in the United States. The extent of disability is generally related to the level of the myelomeningocele defect, with a higher upper level of lesion generally corresponding to greater deficits. Open maternal–fetal
Impact on family and parental stress of prenatal vs postnatal repair of myelomeningocele The Management of Myelomeningocele Study was a multicenter, randomized controlled trial that compared prenatal repair with standard postnatal repair for fetal myelomeningocele.We sought to describe the long-term impact on the families of the women who participated and to evaluate how the timing of repair influenced the impact on families and parental stress.Randomized women completed the 24-item Impact
In utero fetal surgery for myelomeningocele In utero fetal surgery for myelomeningocele In utero fetal surgery for myelomeningocele Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation In utero fetal surgery for myelomeningocele. Lansdale: HAYES, Inc.. Directory Publication. 2012 Authors' conclusions The objective of fetal surgery for myelomeningocele (MMC
Fetal Surgery for Myelomeningocele? 21306233 2011 03 24 2011 03 17 1533-4406 364 11 2011 Mar 17 The New England journal of medicine N. Engl. J. Med. Fetal surgery for myelomeningocele? 1076-7 10.1056/NEJMe1101228 Simpson Joe Leigh JL Greene Michael F MF eng Comment Editorial 2011 02 09 United States N Engl J Med 0255562 0028-4793 AIM IM N Engl J Med. 2011 Mar 17;364(11):993-1004 21306277 Female Fetal Diseases surgery Fetal Therapies Fetus surgery Humans Infant, Newborn Intention to Treat
A randomized trial of prenatal versus postnatal repair of myelomeningocele. Prenatal repair of myelomeningocele, the most common form of spina bifida, may result in better neurologic function than repair deferred until after delivery. We compared outcomes of in utero repair with standard postnatal repair.We randomly assigned eligible women to undergo either prenatal surgery before 26 weeks of gestation or standard postnatal repair. One primary outcome was a composite of fetal or neonatal death (...) months. However, prenatal surgery was associated with an increased risk of preterm delivery and uterine dehiscence at delivery.Prenatal surgery for myelomeningocele reduced the need for shunting and improved motor outcomes at 30 months but was associated with maternal and fetal risks. (Funded by the National Institutes of Health; ClinicalTrials.gov number, NCT00060606.).