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Pineal gland cysts: an evidence synthesis Pineal gland cysts: an evidence synthesis Pineal gland cysts: an evidence synthesis Leggett LE, Sevick LK, Lorenzetti D, Spackman E, Clement F Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Leggett LE, Sevick LK, Lorenzetti D, Spackman E, Clement F . Pineal gland cysts: an evidence synthesis (...) . Calgary: HTA Unit, University of Calgary 2016 Authors' conclusions The evidence published on treatment of pineal gland cysts is weak; however, the literature is in agreement that surgery for symptomatic pineal gland cysts is effective at relieving symptoms. There is no comparative evidence concerning which surgical approach may lead to better outcomes. Surgery does not cause significant long-term side-effects There is no evidence on patient quality of life, attitudes towards treatment of experiences
Pineal gland cysts: an evidence synthesis summary Pineal gland cysts: an evidence synthesis summary Pineal gland cysts: an evidence synthesis summary Health Technology Assessment Unit, University of Calgary Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Health Technology Assessment Unit, University of Calgary. Pineal gland cysts (...) : an evidence synthesis summary. Calgary: HTA Unit, University of Calgary 2016 Authors' conclusions The evidence published on treatment of pineal gland cysts is weak; however, the literature is in agreement that surgery for symptomatic pineal gland cysts is effective at relieving symptoms. There is no comparative evidence concerning which surgical approach may lead to better outcomes. Surgery does not cause significant long-term side-effects . There is no evidence on patient quality of life, attitudes
Cellvizio confocal endomicroscopy system for characterising pancreatic cysts Cellvizio confocal endomicroscop Cellvizio confocal endomicroscopy system for y system for char characterising pancreatic cysts acterising pancreatic cysts Medtech innovation briefing Published: 28 June 2016 nice.org.uk/guidance/mib69 pathways Summary Summary Cellvizio is a confocal laser endomicroscopy (CLE) system with a fibre-optic probe for real-time imaging of tissues. It is designed for use as an adjunct (...) to the standard endoscopic ultrasound- guided fine-needle aspiration (EUS-FNA) procedure, to characterise pancreatic cysts and provide additional information to help guide therapeutic decisions. The evidence summarised in this briefing comes from 2 feasibility and 3 pilot studies with a total of 138 adult patients. The diagnostic accuracy for Cellvizio was reported to be between 71% and 87% in 3 studies compared with histopathology, EUS-FNA or a committee consensus. In 2 studies, images were successfully
The true malignancy rate in 135 patients with preoperative diagnosis of a lateral neck cyst In this study, the true malignancy rate in 135 patients with a preoperative tentative diagnosis of a lateral neck cyst (LNC) was assessed. Furthermore, the sensitivity and specificity of fine needle aspiration of suspected LNC were evaluated and the diagnostic delay was analyzed.This study was retrospective in design and included all patients who had undergone surgery for a suspected LNC in four (...) secondary hospitals in the eastern regions of Denmark during the period of 2009 to 2012.One hundred thirty-five patients were identified and included by means of a search strategy for NOMECO surgical procedure codes KENB40A+B in the electronic surgical booking systems. Because the procedure codes also include median neck cysts and fistulas, the latter were excluded manually.Of the 135 patients preoperatively diagnosed with LNC, a malignant postoperative histopathological diagnosis was revealed in 19
Renal Abscess Caused by Extended-Spectrum Beta-Lactamase-Producing Bacteria and Complicated by the Perforation to a Cyst and to the Renal Pelvis We report a 50-year-old female patient with a left-sided renal abscess caused by extended-spectrum β-lactamase-producing bacteria. According to the ORENUC classification she had phenotype N. The course was complicated by a perforation to an adjacent cyst and later to the renal pelvis. A primarily conservative approach of intravenous antibiotics had
Single-session alcohol sclerotherapy of symptomatic liver cysts using 10â€“20Â min of ethanol exposure: no recurrence at 2â€“16Â years of follow-up To assess long-term results after single-session alcohol sclerotherapy of symptomatic benign liver cysts performed with maximum 20 min of exposure to alcohol.We included 47 patients aged 32-88 years (42 women, 5 men) with 51 benign non-parasitic liver cysts that were exposed to ethanol for 7-20 min in a single sclerotherapy session and were followed (...) for at least 24 months. Each cyst was emptied before injecting ethanol (10% of cyst volume, but maximum 100 mL) into it. The patient rotated from side to side to facilitate contact between ethanol and the whole cyst wall. Pre-treatment cyst volume was defined as the volume of aspirated cyst fluid after complete emptying of the cyst. Follow-up cyst volume was estimated based on computed tomography images.Cyst volumes were 30-4900 (median 520) mL at pre-treatment and 0-230 (median 1) mL at 24-193 (median 56
Pancreatic Cyst Disease: A Review. Cystic lesions of the pancreas are common and increasingly detected in the primary care setting. Some patients have a low risk for developing a malignancy and others have a high risk and need further testing and interventions.Pancreatic cysts may be intraductal mucinous neoplasms, mucinous cystic neoplasms, serous cystadenomas, solid pseudopapillary neoplasms, cystic variations of pancreatic neuroendocrine tumors, pancreatic ductal adenocarcinomas, or 1 (...) of several types of nonneoplastic cysts. Mucinous (intraductal mucinous neoplasm or mucinous cystic neoplasm) lesions have malignant potential and should be distinguished from serous lesions (serous cystadenomas) that are nearly always benign. Symptomatic patients or those having high-risk features on initial imaging (eg, main pancreatic duct dilatation, a solid component, or mural nodule) require further evaluation with advanced imaging, possibly followed by surgical resection. Advanced imaging includes
Hepatic Echinococcal Cysts: A Review Cystic echinococcosis (CE) is a widely endemic helminthic disease caused by infection with metacestodes (larval stage) of the Echinococcus granulosus tapeworm. E. granulosus are common parasites in certain parts of the world, and are present on every continent with the exception of Antarctica. As a result, a large number of people are affected by CE. The increased emigration of populations from endemic areas where prevalence rates are as high as 5-10 (...) % and the relatively quiescent clinical course of CE pose challenges for accurate and timely diagnoses. Upon infection with CE, cyst formation mainly occurs in the liver (70%). Diagnosis involves serum serologic testing for antibodies against hydatid antigens, but preferably with imaging by ultrasound or CT/MRI. Treatment methods include chemotherapy with benzimidazole carbamates and/or surgical approaches, including percutaneous aspiration injection and reaspiration. The success of these methods is influenced
Percutaneous Renal Cyst Ablation and Review of the Current Literature Renal cysts are common and most often are discovered incidentally, but may require intervention if associated with pain, hypertension, or hematuria. Minimally invasive treatment options are preferred with numerous modalities available, including renal cyst ablation. This case report of a 61-year-old female describes the effective percutaneous drainage and endoscopic ablation of a simple parapelvic renal cyst for management
Robot-Assisted Excision of a Urachal Cyst Causing Dyspareunia and Dysorgasmia: Report of a Case Urachal remnants are a group of rare anatomical anomalies that include cysts, diverticula, and tumors. We present a case of a young female patient with dyspareunia and dysorgasmia related to a urachal cyst.A patient with unique presentation of urachal cyst treated robotically. Patient had complete resolution of symptoms postoperatively.Robot-assisted excision of the urachal remnant provided durable
Baker's cyst Baker's cyst - NICE CKS Share Baker's cyst: Summary Baker's cysts (also known as popliteal cysts) are not true cysts. They are a distension of the gastrocnemius-semimembranosus bursa behind the knee. Baker's cysts are described as primary or secondary. Primary cysts are not associated with disease of the knee joint and are found mainly in children. Secondary cysts are associated with underlying disease of the knee joint and have a communication between the bursa and the rest (...) of the knee joint. Almost all Baker's cysts in adults are secondary. The prevalence of Baker's cysts varies widely depending on the population studied, the definition of cyst used, and the diagnostic method. A peak in incidence occurs between 4–7 years of age, with a larger peak between 35–70 years of age. In children: Development of primary Baker's cysts may be related to trauma or local irritation of the bursa. Secondary cysts may occur with conditions such as juvenile idiopathic arthritis
Ovarian Cysts in Postmenopausal Women The Management of Ovarian Cysts in Postmenopausal Women Green-top Guideline No. 34 July 2016The Management of Ovarian Cysts in Postmenopausal Women This is the second edition of this guideline, which was previously published in 2003, and reviewed in 2010, under the title ‘Ovarian Cysts in Postmenopausal Women’. Executive summary of recommendations Diagnosis and significance of ovarian cysts in postmenopausal women How are ovarian cysts diagnosed (...) in postmenopausal women and what initial investigations should be performed? Clinicians should be aware of the different presentations and significance of ovarian cysts in postmenopausal women. [New 2016] In postmenopausal women presenting with acute abdominal pain, the diagnosis of an ovarian cyst accident should be considered (e.g. torsion, rupture, haemorrhage). [New 2016] It is recommended that ovarian cysts in postmenopausal women should be initially assessed by measuring serum cancer antigen 125 (CA125
Arachnoid Cyst. 26352828 2015 09 29 2015 09 10 1533-4406 373 11 2015 Sep 10 The New England journal of medicine N. Engl. J. Med. IMAGES IN CLINICAL MEDICINE. Arachnoid Cyst. e13 10.1056/NEJMicm1413067 Valluru Balakrishna B Royal Liverpool University Hospital, Liverpool, United Kingdom firstname.lastname@example.org. Raj Ray R eng Journal Article United States N Engl J Med 0255562 0028-4793 AIM IM Accidents, Traffic Arachnoid Cysts diagnosis etiology Brain Diseases diagnosis etiology Cerebral Ventricles
Interventions for treating simple bone cysts in the long bones of children. Simple bone cysts, also known as a unicameral bone cysts or solitary bone cysts, are the most common type of benign bone lesion in growing children. Cysts may lead to repeated pathological fracture (fracture that occurs in an area of bone weakened by a disease process). Occasionally, these fractures may result in symptomatic malunion. The main goals of treatment are to decrease the risk of pathological fracture, enhance (...) cyst healing and resolve pain. Despite the numerous treatment methods that have been used for simple bone cysts in long bones of children, there is no consensus on the best procedure.To assess the effects (benefits and harms) of interventions for treating simple bone cysts in the long bones of children, including adolescents.We intended the following main comparisons: invasive (e.g. injections, curettage, surgical fixation) versus non-invasive interventions (e.g. observation, plaster cast
Oral contraceptives for functional ovarian cysts. Functional ovarian cysts are a common gynecological problem among women of reproductive age worldwide. When large, persistent, or painful, these cysts may require operations, sometimes resulting in removal of the ovary. Since early oral contraceptives were associated with a reduced incidence of functional ovarian cysts, many clinicians inferred that birth control pills could be used to treat cysts as well. This became a common clinical practice (...) that included oral contraceptives used for treatment and not prevention of functional ovarian cysts. Criteria for diagnosis of cysts were those used by authors of trials.Two authors independently abstracted data from the articles. One entered the data into RevMan and a second verified accuracy of data entry. For dichotomous outcomes, we computed the Mantel-Haenszel odds ratio with 95% confidence interval (CI). For continuous outcomes, we calculated the mean difference with 95% CI.We identified eight
Cyst carcinoembryonic antigen in differentiating pancreatic cysts: a meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.
Follow-up Imaging for Simple Adnexal Cysts: Clinical Evidence, Cost-Effectiveness and Guidelines TITLE: Follow-up Imaging for Simple Adnexal Cysts: Clinical Evidence, Cost- Effectiveness and Guidelines DATE: 5 November 2013 RESEARCH QUESTIONS 1. What is the clinical evidence regarding follow-up imaging for small simple adnexal cysts? 2. What is the cost effectiveness of follow-up imaging for small simple adnexal cysts? 3. What are the evidence-based guidelines for follow-up imaging (...) and management of small simple adnexal cysts? KEY MESSAGE Two non-randomized studies and three evidence-based guidelines were identified pertaining to follow-up imaging for small, simple, adnexal cysts. No relevant economic information was identified. METHODS A limited literature search was conducted on key resources including PubMed, The Cochrane Library (2013, Issue 10), University of York Centre for Reviews and Dissemination (CRD) databases, Canadian and major international health technology agencies
Effect of longacting somatostatin analogue on kidney and cyst growth in autosomal dominant polycystic kidney disease (ALADIN): a randomised, placebo-controlled, multicentre trial. Autosomal dominant polycystic kidney disease slowly progresses to end-stage renal disease and has no effective therapy. A pilot study suggested that the somatostatin analogue octreotide longacting release (LAR) could be nephroprotective in this context. We aimed to assess the effect of 3 years of octreotide-LAR (...) treatment on kidney and cyst growth and renal function decline in participants with this disorder.We did an academic, multicentre, randomised, single-blind, placebo-controlled, parallel-group trial in five hospitals in Italy. Adult (>18 years) patients with estimated glomerular filtration rate (GFR) of 40 mL/min per 1·73 m(2) or higher were randomly assigned (central allocation by phone with a computerised list, 1:1 ratio, stratified by centre, block size four and eight) to 3 year treatment with two 20
2013LancetControlled trial quality: predicted high