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Interventions for treating simple bone cysts in the long bones of children. Simple bone cysts, also known as a unicameral bone cysts or solitary bone cysts, are the most common type of benign bone lesion in growing children. Cysts may lead to repeated pathological fracture (fracture that occurs in an area of bone weakened by a disease process). Occasionally, these fractures may result in symptomatic malunion. The main goals of treatment are to decrease the risk of pathological fracture, enhance (...) cyst healing and resolve pain. Despite the numerous treatment methods that have been used for simple bone cysts in long bones of children, there is no consensus on the best procedure. This is an update of a Cochrane review first published in 2014.To assess the effects (benefits and harms) of interventions for treating simple bone cysts in the long bones of children, including adolescents.We intended the following main comparisons: invasive (e.g. injections, curettage, surgical fixation) versus non
Ovarian cysts Ovarian cysts - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search Ovarian cysts Last reviewed: February 2019 Last updated: September 2018 Summary A fluid-filled sac in the ovarian tissue. The cyst may be unilocular or multilocular. The causes may be physiological, infectious, benign neoplastic, malignant neoplastic, or metastatic. The most important step in management is assessing the risk of malignancy (...) . Oral contraceptives do not hasten or influence regression of benign ovarian cysts. Asymptomatic post-menopausal women with simple unilocular ovarian cysts <10 cm in diameter and cancer antigen (CA)-125 <35 U/mL can be managed conservatively with serial ultrasonography. Ultrasonography can provide a morphology index score that is useful in determining likelihood of malignancy. Definition Ovarian cyst is a surgical, imaging, or examination finding of an enlarged, fluid-filled ovary or portion
Management of Urinoma Formation After Laparoscopic Cryoablation of Renal Cyst Aim: To describe the presentation and management of a urinoma developing as a complication of laparoscopic cryoablation of a Bosniak III renal cyst. Case: A 74-year-old woman presented with acute onset of severe left lower abdominal pain 1 day after a laparoscopic cryoablation of a 3 cm multilobular left cystic renal mass. CT revealed a perinephric fluid collection adjacent to the lower pole of the left kidney
Single-Incision Laparoscopy Surgery Excision of an Infected Urachal Cyst: Description of the Technique Background: Urachal cysts (UCs) are secondary to incomplete obliteration of the embryonic urachal duct and may become symptomatic when infected. Treatment is primarily surgical to excise the infected cyst. Surgical approaches include a lower midline laparotomy or minimally invasive (MI) techniques. Case: We present a case of a young male with an infected UC that was treated with a single
Word catheter and marsupialisation in women with a cyst or abscess of the Bartholin gland (WoMan-trial): a randomised clinical trial To compare recurrence of a cyst or abscess of the Bartholin gland after surgical treatment using a Word catheter or marsupialisation.Multicentre, open-label, randomised controlled trial.Eighteen hospitals in the Netherlands and one hospital in England.Women with a symptomatic cyst or abscess of the Bartholin gland.Women were randomised to treatment with Word (...) catheter or marsupialisation.The primary outcome was recurrence of the cyst or abscess within 1 year of treatment. The secondary outcomes included pain during and after treatment (measured on a 10-point scale), use of analgesics, and time from diagnosis to treatment. Analysis was by intention-to-treat. To assess whether marsupialisation would reduce the recurrence rate by 5% (from 20 to 15%) we needed to include 160 women (alpha error 0.05, beta error 0.2).One hundred and sixty-one women were randomly
The Longitudinal Study of Liver Cysts inÂ Patients With Autosomal Dominant Polycystic Kidney Disease and Polycystic Liver Disease Although polycystic liver disease (PCLD) is one of the extrarenal complications in patients with autosomal dominant polycystic kidney disease (ADPKD), longitudinal changes and the association with total liver volume (TLV) have not been clearly elucidated yet.Patients with ADPKD were chosen who underwent computed tomography or magnetic resonance imaging twice or more (...) during August 2003 through December 2015. TLV, each cyst volume, and the proportion of parenchyma were measured. The natural history of liver cysts and the association between TLV and liver cysts were evaluated. To compare with liver cysts in ADPKD patients with PCLD, simple liver cysts in patients without ADPKD were also evaluated.TLV at baseline and its growth rate in all the patients with ADPKD, whose serum creatinine, estimated glomerular filtration rate, and total kidney volume were 1.45 mg/dl
Conservative approach to a large dentigerous cyst in an 11-year-old patient Dentigerous cyts are form of benevolent odontogenic cyts which are related to crowns of permament teeth. Often, they are described as unilocular radiolucent lesions and barely seen in childhood era. This article aims to show a case about 11 year old boy having a dentigerous cyst associated with the mandibular canine and a premolar. Extraction of the primary molars and marsupialization of the lesion is also included (...) in this method of treatment. After 9 months of the treatment, impacted teeth spontaneously erupted. Therefore, if we aim to manage of dentigerous cysts in children conservatively, marsupialization might be considered as first and foremost treatment method.
Inhibition of cyst growth in PCK and Wpk rat models of polycystic kidney disease with low doses of peroxisome proliferator-activated receptor Î³ agonists The studies were designed to test the efficacy of two peroxisome proliferator-activated receptor γ (PPARγ) agonists in two rodent models of polycystic kidney disease (PKD).The PCK rat is a slowly progressing cystic model while the Wpk-/- rat is a rapidly progressing model. PCK rats were fed with a pharmacological (0.4 mg/kg body weight [BW (...) human doses for both drugs.The current studies demonstrate: 1) that low, pharmacologically relevant, doses of the PPARγ agonists effectively inhibit cyst growth; 2) there is a class action of the drugs with both commercially available PPARγ agonists, rosiglitazone, and pioglitazone, inhibiting cyst growth; 3) the drugs showed efficacy in two different preclinical cystic models. In the PCK rat, animals fed with a sub-pharmacological dose of rosiglitazone for 24 weeks had significantly lower kidney
Choledochal cyst in pregnancy Biliary diseases during pregnancy are not uncommon and are frequently due to cholelithiasis. Choledochal cyst during pregnancy is rare. The management of biliary pathologies during pregnancy poses a challenge as the window of opportunity to carry out any interventions with minimal risk is small.We report the case of a lady who was diagnosed with a large type I choledochal cyst during the second trimester of pregnancy. Due to increasing symptoms and recurrent (...) cholangitis, she was managed with antibiotics and surgical resection. She remained well and delivered a healthy baby boy.Clinicians need to consider choledochal cyst as a differential in pregnant patients presenting with upper abdominal fullness.
Fukuoka criteria accurately predict risk for adverse outcomes during follow-up of pancreatic cysts presumed to be intraductal papillary mucinous neoplasms Fukuoka consensus guidelines classify pancreatic cystic lesions (PCLs) presumed to be intraductal papillary mucinous neoplasms (IPMNs) into Fukuoka positive (FP) (subgroups of high-risk (HR) and worrisome features (WFs)) and Fukuoka negative (FN) (non-HR feature/WF cysts). We retrospectively estimated 5-year risk of pancreatic cancer (PC (...) ) in FN, WF and HR cysts of patients with PCL-IPMN.From Mayo Clinic databases, we randomly selected 2000 patients reported to have a PCL; we excluded inflammatory or suspected non-IPMN cysts and those without imaging follow-up. We re-reviewed cross-sectional imaging and abstracted clinical and follow-up data on PCL-IPMNs. The study contained 802 patients with FN cysts and 358 with FP cysts.Patients with PCL-IPMN had median (IQR) follow-up of 4.2 (1.8-7.1) years. Among FN cysts, 5-year PC risk was low
Pineal gland cysts: an evidence synthesis Pineal gland cysts: an evidence synthesis Pineal gland cysts: an evidence synthesis Leggett LE, Sevick LK, Lorenzetti D, Spackman E, Clement F Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Leggett LE, Sevick LK, Lorenzetti D, Spackman E, Clement F . Pineal gland cysts: an evidence synthesis (...) . Calgary: HTA Unit, University of Calgary 2016 Authors' conclusions The evidence published on treatment of pineal gland cysts is weak; however, the literature is in agreement that surgery for symptomatic pineal gland cysts is effective at relieving symptoms. There is no comparative evidence concerning which surgical approach may lead to better outcomes. Surgery does not cause significant long-term side-effects There is no evidence on patient quality of life, attitudes towards treatment of experiences
Pineal gland cysts: an evidence synthesis summary Pineal gland cysts: an evidence synthesis summary Pineal gland cysts: an evidence synthesis summary Health Technology Assessment Unit, University of Calgary Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Health Technology Assessment Unit, University of Calgary. Pineal gland cysts (...) : an evidence synthesis summary. Calgary: HTA Unit, University of Calgary 2016 Authors' conclusions The evidence published on treatment of pineal gland cysts is weak; however, the literature is in agreement that surgery for symptomatic pineal gland cysts is effective at relieving symptoms. There is no comparative evidence concerning which surgical approach may lead to better outcomes. Surgery does not cause significant long-term side-effects . There is no evidence on patient quality of life, attitudes
Cellvizio confocal endomicroscopy system for characterising pancreatic cysts Cellvizio confocal endomicroscop Cellvizio confocal endomicroscopy system for y system for char characterising pancreatic cysts acterising pancreatic cysts Medtech innovation briefing Published: 28 June 2016 nice.org.uk/guidance/mib69 pathways Summary Summary Cellvizio is a confocal laser endomicroscopy (CLE) system with a fibre-optic probe for real-time imaging of tissues. It is designed for use as an adjunct (...) to the standard endoscopic ultrasound- guided fine-needle aspiration (EUS-FNA) procedure, to characterise pancreatic cysts and provide additional information to help guide therapeutic decisions. The evidence summarised in this briefing comes from 2 feasibility and 3 pilot studies with a total of 138 adult patients. The diagnostic accuracy for Cellvizio was reported to be between 71% and 87% in 3 studies compared with histopathology, EUS-FNA or a committee consensus. In 2 studies, images were successfully