Latest & greatest articles for Cornea

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Top results for Cornea

1. Delayed-onset Candida parapsilosis cornea tunnel infection and endophthalmitis after cataract surgery: Histopathology and clinical course (Full text)

Delayed-onset Candida parapsilosis cornea tunnel infection and endophthalmitis after cataract surgery: Histopathology and clinical course To describe a patient with late post-operative endophthalmitis and clear cornea tunnel infection caused by Candida parapsilosis that was masquerading as chronic anterior uveitis.A 62-year old woman with history of uncomplicated cataract surgery 7 months prior and chronic postoperative anterior uveitis, presented with an endothelial plaque, hypopyon

2018 American journal of ophthalmology case reports

2. Case of progressive hyperopia due to flattening of cornea (Full text)

Case of progressive hyperopia due to flattening of cornea To report a case that had a progressive decrease in the visual acuity caused by a progressive increase in the hyperopia due to a flattening of the cornea.A 50-year-old woman complained of decreased vision in both eyes. Her decimal best-corrected visual acuity was 1.2 in the right and 0.5 in the left eyes, and the refractive error (spherical equivalent) was +3.75 diopters (D) for the right eye and +6.5 D for the left eye. Slit-lamp (...) examinations showed clear corneas but Descemet's folds and fine pigmentations and opacities were present beneath the corneal epithelium in both eyes. Analysis of the corneal shape by anterior segment optical coherence tomography showed that the corneas were flattened, and the corneal refractive power was decreased in both eyes. The large values of the higher-order aberration in the cornea and total eye displayed bilateral irregular astigmatism. She obtained good vision by wearing hard contact lenses

2018 American journal of ophthalmology case reports

3. University students' knowledge of corneal donation and willingness to donate corneas in the occupied Palestinian territory: a cross-sectional study. (Full text)

University students' knowledge of corneal donation and willingness to donate corneas in the occupied Palestinian territory: a cross-sectional study. Access to corneal transplantation is limited worldwide because of poor knowledge. Ethical, religious, and cultural barriers contribute to low rates of corneal donation. In the occupied Palestinian territory, limited information is available on factors affecting corneal donation. The aim of this study was to assess the knowledge and willingness (...) %) respondents were aware of a lack in corneal donation, but 274 (64%; p=0·01) of these respondents did not show willingness towards corneal donation. 429 (68%) respondents were not willing to donate their corneas, the most common reasons being disapproval by family members and poor awareness. We found no association between sociodemographic factors and willingness was determined.Palestinian students are aware of the lack of local cornea donation but are unwilling to donate their corneas. The study results

2018 Lancet

4. A new worm infiltrating the human cornea: A report of three cases (Full text)

A new worm infiltrating the human cornea: A report of three cases To characterize a new species of parasitic nematode that triggers uveitis.Three previously healthy, relatively young people each contracted a corneal stromal nematode that, upon surgical removal and examination, did not match any known nematodes. Clinical ocular findings included corneal opacification, visible corneal worms, conjunctival injection, and uveitis.The three cases presented here represent a previously undescribed (...) parasitic infection of the cornea by an unidentified nematode. These findings may represent a previously unrecognized zoonotic infection from wildlife sources and potentially a newly documented nematode requiring description. Future clinical findings regarding this newly described nematode are needed to further develop our understanding of the disease.

2018 American journal of ophthalmology case reports

5. A case of hypertrophic herpes simplex virus affecting the eyelid and cornea masquerading as IgG4-related disease (Full text)

A case of hypertrophic herpes simplex virus affecting the eyelid and cornea masquerading as IgG4-related disease To report a case of hypertrophic herpes simplex virus (HSV) of the eyelid and cornea masquerading as IgG4-related disease.A 37-year old African American female with a past medical history of human immunodeficiency virus (HIV) on highly active antiretroviral therapy (HAART) and a recent history of treated genital herpes, presented with an ulcerative lesion of the left upper and lower

2017 American journal of ophthalmology case reports

6. A case of fungal keratitis and endophthalmitis post penetrating keratoplasty resulting from fungal contamination of the donor cornea (Full text)

A case of fungal keratitis and endophthalmitis post penetrating keratoplasty resulting from fungal contamination of the donor cornea Fungal infections post keratoplasty due to contamination of the donor corneal graft have become important issues that need to be addressed. Here we report a case of fungal keratitis and endophthalmitis post penetrating keratoplasty (PKP) due to fungal contamination of the donor corneal graft.We present a 52-year-old male who underwent PKP with a donor corneal

2016 American journal of ophthalmology case reports

7. The effect of donor cornea endothelial cell count for Descemet stripping endothelial keratoplasty

The effect of donor cornea endothelial cell count for Descemet stripping endothelial keratoplasty Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence: Organisation web address

2016 PROSPERO

8. Use of magnetic nanoparticles and oscillating magnetic field for non-viral gene transfer into mouse cornea. (PubMed)

Use of magnetic nanoparticles and oscillating magnetic field for non-viral gene transfer into mouse cornea. Inherited, iatrogenic, and metabolic corneal disease could be potentially treated by supplying a functional gene or changing the expression levels of specific genes. Viral-based gene therapy is efficient, but restricted by evoking immune responses and inflammation. This study aimed to transfect mouse cornea with a non-viral based (oscillating magnetofection) method.Cultured mouse corneas (...) were treated with magnetic nanoparticles (MNP) tethered to CAG promoter and green fluorescent protein (GFP) reporter plasmids exposed to a 1 Hz, 2 Hz, and 4 Hz oscillating magnetic field for 30 min and 60 min and in three DNA:MNP ratios (1:2, 1:1, 2:3). Corneas were cultured for up to 3 days and their green fluorescent channel intensity and number of GFP-positive cells were recorded. Transfection efficiency was estimated as the percentage of GFP-positive cells per total cells in a microscopic

2015 Lancet

9. Artificial corneas versus donor corneas for repeat corneal transplants. (PubMed)

Artificial corneas versus donor corneas for repeat corneal transplants. Individuals who have failed one or more full thickness penetrating keratoplasties (PKs) may be offered repeat corneal surgery using an artificial or donor cornea. An artificial or prosthetic cornea is known as a keratoprosthesis. Both donor and artificial corneal transplantations involve removal of the diseased and opaque recipient cornea (or the previously failed cornea) and replacement with another donor or prosthetic (...) cornea.To assess the effectiveness of artificial versus donor corneas in individuals who have had one or more failed donor corneal transplantations.We searched CENTRAL (which contains the Cochrane Eyes and Vision Group Trials Register) (2013, Issue 10), Ovid MEDLINE, Ovid MEDLINE In-Process and Other Non-Indexed Citations, Ovid MEDLINE Daily, Ovid OLDMEDLINE (January 1946 to November 2013), EMBASE (January 1980 to November 2013), Latin American and Caribbean Health Sciences Literature Database (LILACS

2014 Cochrane

10. Xanthelasmata, arcus corneae, and ischaemic vascular disease and death in general population: prospective cohort study. (Full text)

Xanthelasmata, arcus corneae, and ischaemic vascular disease and death in general population: prospective cohort study. To test the hypothesis that xanthelasmata and arcus corneae, individually and combined, predict risk of ischaemic vascular disease and death in the general population.Prospective population based cohort study.The Copenhagen City Heart Study.12,745 people aged 20-93 years free of ischaemic vascular disease at baseline and followed from 1976-8 until May 2009 with 100% complete (...) follow-up.Hazard ratios for myocardial infarction, ischaemic heart disease, ischaemic stroke, ischaemic cerebrovascular disease, and death; odds ratios for severe atherosclerosis.563 (4.4%) of participants had xanthelasmata and 3159 (24.8%) had arcus corneae at baseline. During 33 years' follow-up (mean 22 years), 1872 developed myocardial infarction, 3699 developed ischaemic heart disease, 1498 developed ischaemic stroke, 1815 developed ischaemic cerebrovascular disease, and 8507 died

2011 BMJ

11. Keratoprosthesis for the treatment of severe bilateral cornea disease

Keratoprosthesis for the treatment of severe bilateral cornea disease Keratoprosthesis for the treatment of severe bilateral cornea disease Keratoprosthesis for the treatment of severe bilateral cornea disease Alberta Heritage Foundation for Medical Research Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Alberta Heritage Foundation (...) for Medical Research. Keratoprosthesis for the treatment of severe bilateral cornea disease. Edmonton: Alberta Heritage Foundation for Medical Research (AHFMR). Technote TN 27. 2001 Authors' objectives

This report summarises the available literature on keratoprosthesis (KPro), an artificial cornea, as a treatment for adult patients with severe cornea disease.

Authors' conclusions The rational for using KPro is that patients reciving corneal transplantation show variable success rates and a minority

2001 Health Technology Assessment (HTA) Database.