Latest & greatest articles for Cerebral Aneurysm

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Top results for Cerebral Aneurysm

1. Comparative effectiveness of prophylactic therapies for cerebral vasospasm secondary to aneurysmal subarachnoid hemorrhage: a network meta-analysis of randomized trials

Comparative effectiveness of prophylactic therapies for cerebral vasospasm secondary to aneurysmal subarachnoid hemorrhage: a network meta-analysis of randomized trials Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability

2019 PROSPERO

2. A systematic review of intraoperative complications of cerebral aneurysm surgery

A systematic review of intraoperative complications of cerebral aneurysm surgery Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email

2019 PROSPERO

3. Procedural complexity independent of P2Y12 reaction unit (PRU) values is associated with acute in situ thrombosis in Pipeline flow diversion of cerebral aneurysms (PubMed)

Procedural complexity independent of P2Y12 reaction unit (PRU) values is associated with acute in situ thrombosis in Pipeline flow diversion of cerebral aneurysms Acute in situ thrombosis is an ischaemic phenomenon during Pipeline embolisation device (PED) procedures with potentially high morbidity and mortality. There is controversy regarding the role of platelet function testing with P2Y12 assay as a predictor of intraprocedural thromboembolic events. There is limited knowledge on whether (...) procedural complexity influences these events.Data were collected retrospectively on 742 consecutive PED cases at a single institution. Patients with intraprocedural acute thrombosis were compared with patients without these events.A cohort of 37 PED cases with acute in situ thrombosis (mean age 53.8 years, mean aneurysm size 8.4 mm) was matched with a cohort of 705 PED cases without intraprocedural thromboembolic events (mean age 56.4 years, mean aneurysm size 6.9 mm). All patients with in situ

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2018 Stroke and vascular neurology

4. Cerebral aneurysm

Cerebral aneurysm Cerebral aneurysm - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Cerebral aneurysm Last reviewed: February 2019 Last updated: April 2018 Summary Typically asymptomatic until ruptured, resulting in a subarachnoid haemorrhage. Head CT usually confirms the diagnosis of subarachnoid haemorrhage, but lumbar puncture is indicated if the CT is negative and suspicion persists. Cerebral angiogram (...) is the definitive investigation. CT angiography or magnetic resonance angiography may also be used. Definitive treatment aims to obliterate the aneurysm from the cerebral circulation. Options include endovascular coiling or open surgical clipping. Screening with non-invasive neuroangiography is recommended for at-risk populations. Definition A cerebral aneurysm is a focal abnormal dilation of the wall of an artery in the brain. Intra-cranial aneurysms are most commonly located at branching points of the major

2018 BMJ Best Practice

5. Adenosine to facilitate the clipping of cerebral aneurysms: literature review (PubMed)

Adenosine to facilitate the clipping of cerebral aneurysms: literature review Cerebral aneurysms have a high mortality rate when ruptured. Endovascular techniques have improved substantially in treating this pathology. However, surgical clip ligation remains the preferred option for some aneurysms. Various techniques are used intraoperatively to assist the surgeon in dissecting the aneurysmal dome free of surrounding tissue and placing a clip around the neck safely and effectively so

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2017 Stroke and vascular neurology

6. Cerebral aneurysm treatment: modern neurovascular techniques (PubMed)

Cerebral aneurysm treatment: modern neurovascular techniques Endovascular treatment of cerebral aneurysm continues to evolve with the development of new technologies. This review provides an overview of the recent major innovations in the neurointerventional space in recent years.

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2016 Stroke and vascular neurology

7. The durability of endovascular coiling versus neurosurgical clipping of ruptured cerebral aneurysms: 18 year follow-up of the UK cohort of the International Subarachnoid Aneurysm Trial (ISAT). (PubMed)

The durability of endovascular coiling versus neurosurgical clipping of ruptured cerebral aneurysms: 18 year follow-up of the UK cohort of the International Subarachnoid Aneurysm Trial (ISAT). Previous analyses of the International Subarachnoid Aneurysm Trial (ISAT) cohort have reported on the risks of recurrent subarachnoid haemorrhage and death or dependency for a minimum of 5 years and up to a maximum of 14 years after treatment of a ruptured intracranial aneurysm with either neurosurgical (...) clipping or endovascular coiling. At 1 year there was a 7% absolute and a 24% relative risk reduction of death and dependency in the coiling group compared with the clipping group, but the medium-term results showed the increased need for re-treatment of the target aneurysm in the patients given coiling. We report the long-term follow-up of patients in this UK cohort.In ISAT, patients were randomly allocated to either neurosurgical clipping or endovascular coiling after a subarachnoid haemorrhage

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2015 Lancet

8. The durability of endovascular coiling versus neurosurgical clipping of ruptured cerebral aneurysms: 18 year follow-up of the UK cohort of the International Subarachnoid Aneurysm Trial (ISAT). (PubMed)

The durability of endovascular coiling versus neurosurgical clipping of ruptured cerebral aneurysms: 18 year follow-up of the UK cohort of the International Subarachnoid Aneurysm Trial (ISAT). Previous analyses of the International Subarachnoid Aneurysm Trial (ISAT) cohort have reported on the risks of recurrent subarachnoid haemorrhage and death or dependency for a minimum of 5 years and up to a maximum of 14 years after treatment of a ruptured intracranial aneurysm with either neurosurgical (...) clipping or endovascular coiling. At 1 year there was a 7% absolute and a 24% relative risk reduction of death and dependency in the coiling group compared with the clipping group, but the medium-term results showed the increased need for re-treatment of the target aneurysm in the patients given coiling. We report the long-term follow-up of patients in this UK cohort.In ISAT, patients were randomly allocated to either neurosurgical clipping or endovascular coiling after a subarachnoid haemorrhage

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2015 Lancet

9. Onyx liquid embolic system (Onyx HD-500) (Covidien ev3 Neurovascular) for treatment of cerebral aneurysms

Onyx liquid embolic system (Onyx HD-500) (Covidien ev3 Neurovascular) for treatment of cerebral aneurysms Onyx liquid embolic system (Onyx HD-500) (Covidien / ev3 Neurovascular) for treatment of cerebral aneurysms Onyx liquid embolic system (Onyx HD-500) (Covidien / ev3 Neurovascular) for treatment of cerebral aneurysms Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database (...) . Citation Onyx liquid embolic system (Onyx HD-500) (Covidien / ev3 Neurovascular) for treatment of cerebral aneurysms. Lansdale: HAYES, Inc.. Healthcare Technology Brief Publication. 2014 Authors' conclusions Aneurysms of the intracranial circulation are serious and potentially life-threatening disorders. An aneurysm is a weakened area in the wall of an artery caused by congenital defects in the vascular wall combined with degenerative changes that cause bulging, which can lead to rupture. Rupture

2014 Health Technology Assessment (HTA) Database.

10. Prevalence of Unruptured Cerebral Aneurysms in Chinese Adults Aged 35 to 75 Years: A Cross-sectional Study. (PubMed)

Prevalence of Unruptured Cerebral Aneurysms in Chinese Adults Aged 35 to 75 Years: A Cross-sectional Study. The reported prevalence of unruptured cerebral aneurysms (UCAs) varies widely.To measure the prevalence of UCAs by using 3-dimensional time-of-flight magnetic resonance angiography in adults aged 35 to 75 years.Cross-sectional study done between June 2007 and June 2011.Two communities chosen at random from 2 districts (1 urban and 1 suburban) in Shanghai, China.4813 adults aged 35 to 75

2013 Annals of Internal Medicine

11. Effects of cilostazol on cerebral vasospasm after aneurysmal subarachnoid hemorrhage: a multicenter prospective, randomized, open-label blinded end point trial (PubMed)

Effects of cilostazol on cerebral vasospasm after aneurysmal subarachnoid hemorrhage: a multicenter prospective, randomized, open-label blinded end point trial Cerebral vasospasm following aneurysmal subarachnoid hemorrhage (SAH) is a major cause of subsequent morbidity and mortality. Cilostazol, a selective inhibitor of phosphodiesterase 3, may attenuate cerebral vasospasm because of its antiplatelet and vasodilatory effects. A multicenter prospective randomized trial was conducted (...) to investigate the effect of cilostazol on cerebral vasospasm.Patients admitted with SAH caused by a ruptured anterior circulation aneurysm who were in Hunt and Kosnik Grades I to IV and were treated by clipping within 72 hours of SAH onset were enrolled at 7 neurosurgical sites in Japan. These patients were assigned to one of 2 groups: the usual therapy group (control group) or the add-on 100 mg cilostazol twice daily group (cilostazol group). The group assignments were done by a computer-generated

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2012 EvidenceUpdates

12. Residual flow after cerebral aneurysm coil occlusion: diagnostic accuracy of MR angiography (PubMed)

Residual flow after cerebral aneurysm coil occlusion: diagnostic accuracy of MR angiography The purpose of this study was to estimate the performance measures of MR angiography (MRA) in the diagnosis of aneurysm residual flow after coil occlusion.Patients having at least 1 cerebral aneurysm treated with coil occlusion were prospectively and consecutively enrolled. Time of flight and contrast-enhanced MRA were performed the same day of the DSA follow-up. The degree of aneurysm occlusion (...) and dimensions of the residual flow were evaluated by independent readers at MRA and digital subtraction angiogram. MRA performance measures were estimated in a cross-sectional analysis and repeated in subgroups of aneurysm sizes and locations. MRA predictive values for recurrence were also estimated using a longitudinal design.We obtained 167 aneurysm evaluations for each imaging modality. Class 3 residual flow was seen on digital subtraction angiogram follow-up in 27%. The sensitivity and specificity

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2012 EvidenceUpdates

13. The natural course of unruptured cerebral aneurysms in a Japanese cohort. (PubMed)

The natural course of unruptured cerebral aneurysms in a Japanese cohort. The natural history of unruptured cerebral aneurysms has not been clearly defined.From January 2001 through April 2004, we enrolled patients with newly identified, unruptured cerebral aneurysms in Japan. Information on the rupture of aneurysms, deaths, and the results of periodic follow-up examinations were recorded. We included 5720 patients 20 years of age or older (mean age, 62.5 years; 68% women) who had saccular (...) aneurysms that were 3 mm or more in the largest dimension and who initially presented with no more than a slight disability.Of the 6697 aneurysms studied, 91% were discovered incidentally. Most aneurysms were in the middle cerebral arteries (36%) and the internal carotid arteries (34%). The mean (±SD) size of the aneurysms was 5.7±3.6 mm. During a follow-up period that included 11,660 aneurysm-years, ruptures were documented in 111 patients, with an annual rate of rupture of 0.95% (95% confidence

2012 NEJM

14. Diagnosing cerebral aneurysms by computed tomographic angiography: meta-analysis

Diagnosing cerebral aneurysms by computed tomographic angiography: meta-analysis Diagnosing cerebral aneurysms by computed tomographic angiography: meta-analysis Diagnosing cerebral aneurysms by computed tomographic angiography: meta-analysis Menke J, Larsen J, Kallenberg K CRD summary This review concluded that computed tomography (CT) angiography had high accuracy in diagnosing cerebral aneurysms, specifically when using modern multidetector CT. Although there were some limitations (...) a diagnostic filter. Reference lists of retrieved articles were screened. Study selection Studies that evaluated contrast enhanced helical CT angiography (index test) against digital subtraction angiography (DSA) (reference standard) for primary diagnosis of any type of cerebral aneurysm (target condition) in patients clinically suspected of having a cerebral aneurysm were eligible for inclusion. Studies had to report sufficient data to construct a 2x2 table of test performance on at least a per-patient

2012 DARE.

15. Invasive interventional management of post-hemorrhagic cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage

Invasive interventional management of post-hemorrhagic cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage Invasive interventional management of post-hemorrhagic cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage Todd Abruzzo, 1 Christopher Moran, 2 Kristine A Blackham, 3 Clifford J Eskey, 4 Raisa Lev, 5 Philip Meyers, 6 Sandra Narayanan, 7 Charles Joseph Prestigiacomo 8 ABSTRACT Current clinical practice standards are addressed for the invasive (...) interventional management of post- hemorrhagic cerebral vasospasm (PHCV) in patients with aneurysmal subarachnoid hemorrhage. The conclusions, based on an assessment by the Standards Committee of the Society of Neurointerventional Surgery, included a critical review of the literature using guidelines for evidence based medicine proposed bytheStrokeCounciloftheAmericanHeart Association and the University of Oxford, Centre for Evidence Based Medicine. Speci?cally examined were the safety and ef?cacy

2012 Society of NeuroInterventional Surgery

16. Diagnosing cerebral aneurysms by computed tomographic angiography: Meta-analysis (PubMed)

Diagnosing cerebral aneurysms by computed tomographic angiography: Meta-analysis Cerebral aneurysms can cause substantial morbidity and mortality, specifically if they rupture, leading to nontraumatic subarachnoid hemorrhage (SAH). This meta-analysis summarizes evidence about the accuracy of noninvasive computed tomographic (CT) angiography for diagnosing intracranial aneurysms in symptomatic patients.Four databases including PubMed were searched without language restrictions from January 1995 (...) to February 2010. Two independent reviewers selected and extracted 45 studies that compared CT angiography with digital subtraction angiography (DSA) and/or intraoperative findings in patients suspected of having cerebral aneurysms. Data from eligible studies were used to reconstruct 2 x 2 contingency tables on a per-patient basis in at least 5 diseased and 5 nondiseased patients, with additional data on a per-aneurysm basis when available.The 45 included studies generally were of high methodological

2011 EvidenceUpdates

17. Effect of statin treatment on vasospasm, delayed cerebral ischemia, and functional outcome in patients with aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis update (PubMed)

Effect of statin treatment on vasospasm, delayed cerebral ischemia, and functional outcome in patients with aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis update A recent meta-analysis investigating the efficacy of statin treatment in patients with aneurysmal subarachnoid hemorrhage reported a reduced incidence of vasospasm, delayed cerebral ischemia, and mortality in statin-treated patients. However, the meta-analysis was criticized for its methodology, and several (...) retrospective studies found no beneficial effect. We present the results of a new systematic review, which differs from the previous systematic review in its methodology, and by inclusion of the results of a fourth randomized, placebo-controlled trial. Summary of Review- All randomized, placebo-controlled trials investigating the effect of statins on vasospasm, delayed cerebral ischemia, and functional outcome in patients with aneurysmal subarachnoid hemorrhage were included. Outcomes were the number

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2010 EvidenceUpdates

18. Effect of different components of triple-H therapy on cerebral perfusion in patients with aneurysmal subarachnoid haemorrhage: a systematic review

Effect of different components of triple-H therapy on cerebral perfusion in patients with aneurysmal subarachnoid haemorrhage: a systematic review Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2010 DARE.

19. Reporting Standards for Endovascular Repair of Saccular Intracranial Cerebral Aneurysms

Reporting Standards for Endovascular Repair of Saccular Intracranial Cerebral Aneurysms Reporting Standards for Endovascular Repair of Saccular Intracranial Cerebral Aneurysms Philip M. Meyers, MD, H. Christian Schumacher, MD, Randall T. Higashida, MD, Colin P. Derdeyn, MD, Gary M. Nesbit, MD, David Sacks, MD, Lawrence R. Wechsler, MD, Joshua B. Bederson, MD, Sean D. Lavine, MD, and Peter Rasmussen, MD BACKGROUND AND PURPOSE: The goal of this article is to provide consensus recommendations (...) publications. CONCLUSIONS:Theevaluationandtreatmentofbrainaneurysmsofteninvolvemultiplemedicalspecialties.Recent reviewsbytheAmericanHeartAssociationhavesurveyedthemedicalliteraturetodevelopguidelinesfortheclinical management of ruptured and unruptured cerebral aneurysms. Despite efforts to synthesize existing knowledge on cerebral aneurysm evaluation and treatment, significant inconsistencies remain in nomenclature and definition for research and reporting purposes. These operational definitions were

2009 Society of Interventional Radiology

20. The impact of a highly visible display of cerebral perfusion pressure on outcome in individuals with cerebral aneurysms (PubMed)

The impact of a highly visible display of cerebral perfusion pressure on outcome in individuals with cerebral aneurysms Nurses' ability to rapidly detect decreases in cerebral perfusion pressure (CPP), which may contribute to secondary brain injury, may be limited by poor visibility of CPP displays.To evaluate the impact of a highly visible CPP display on the functional outcome in individuals with cerebral aneurysms.Patients with cerebral aneurysms (n = 100) who underwent continuous CPP

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2008 EvidenceUpdates