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Latest & greatest articles for CNS Infection
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[ ]: Immunocompromised state (eg, HIV infection, immunosuppressive therapy, solid organ or hematopoietic stem cell transplantation) History of centralnervoussystem (CNS) disease (mass lesion, stroke, or focal infection) New onset seizure (within one week of presentation) Papilledema Abnormal level of consciousness Focal neurologic deficit Patients with these clinical risk factors should have a CT scan to identify a possible mass lesion and other causes of increased intracranial pressure. However, it has been (...) granulomatosis ● Centralnervoussystem (CNS) vasculitis ● Rheumatoid arthritis ● Kawasaki’s disease ● Sarcoidosis ● Leptomeningeal cancer ● Post-transplantation lymphoproliferative disorder ● Behçet’s disease ● Vogt-Koyanagi syndrome Parasites ● Toxoplasma gondii ● Neurocysticercosis ● Trichinosis ● Naegleria ● Hartmannella ● Bartonella henselae Neoplastic Disorders ● Leukemia ● Carcinomatous meningitis secondary to primary or secondary tumors of ● the brain Rickettsiae ● Rocky Mountain spotted fever
Randomized Controlled Trial Comparing Cerebral Perfusion Pressure-Targeted Therapy Versus Intracranial Pressure-Targeted Therapy for Raised Intracranial Pressure due to Acute CNSInfections in Children PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?
administered treatment has failed or where there are limited available options, but that data was limited. Owing to methodological limitations these conclusions may not be reliable. Authors' objectives To assess the effectiveness and safety of linezolid for the treatment of patients with centralnervoussystem (CNS) infections. Searching PubMed, Current Contents and the Cochrane Library were searched to October 2006. Search terms were reported. The authors also searched the reference lists of included (...) Linezolid for the treatment of patients with centralnervoussysteminfection Linezolid for the treatment of patients with centralnervoussysteminfection Linezolid for the treatment of patients with centralnervoussysteminfection Ntziora F, Falagas M E CRD summary This review assessed the effectiveness of linezolid for the treatment of patients with centralnervoussysteminfections. The authors concluded linezolid may be considered for the treatment of these infections where previously
Centralnervoussysteminfection in congenital syphilis. Identification of infants with Treponema pallidum infection of the centralnervoussystem remains challenging.We used rabbit-infectivity testing of the cerebrospinal fluid to detect T. pallidum infection of the centralnervoussystem in infants born to mothers with syphilis. The results were compared with those of clinical, radiographic, and conventional laboratory evaluations; IgM immunoblotting of serum and cerebrospinal fluid (...) normal findings on clinical evaluation had a positive cerebrospinal fluid rabbit-infectivity test. Overall, centralnervoussysteminfection was best predicted by IgM immunoblotting of serum or PCR assay of serum or blood.Most infants with T. pallidum infection of the centralnervoussystem can be identified by physical examination, conventional laboratory tests, and radiographic studies. However, the identification of all such infants requires the use of additional tests, including IgM