Family Identification of Delirium in the Emergency Department in Patients With and Without Dementia: Validity of the Family Confusion Assessment Method (FAM-CAM) Family Identification of Delirium in the Emergency Department in Patients With and Without Dementia: Validity of the Family Confusion Assessment Method (FAM-CAM) - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced (...) citation management software Create file Cancel Actions Cite Share Permalink Copy Page navigation J Am Geriatr Soc Actions . 2020 Apr 10. doi: 10.1111/jgs.16438. Online ahead of print. Family Identification of Delirium in the Emergency Department in Patients With and Without Dementia: Validity of the Family Confusion Assessment Method (FAM-CAM) , , , , , Affiliations Expand Affiliations 1 Department of Pharmacy and Health System Sciences, Northeastern University, Boston, Massachusetts, USA. 2

Comparing Major Bleeding Risk in Outpatients With Atrial Fibrillation or Flutter by Oral Anticoagulant Type (from the National Cardiovascular Disease Registry`s Practice Innovation and Clinical Excellence Registry) Comparing Major Bleeding Risk in Outpatients With Atrial Fibrillation or Flutter by Oral Anticoagulant Type (From the National Cardiovascular Disease Registry's Practice Innovation and Clinical Excellence Registry) - PubMed This site needs JavaScript to work properly. Please enable (...) al. J Manag Care Spec Pharm. 2020 May;26(5):639-651. doi: 10.18553/jmcp.2020.26.5.639. J Manag Care Spec Pharm. 2020. PMID: 32347184 Gupta K, Trocio J, Keshishian A, Zhang Q, Dina O, Mardekian J, Rosenblatt L, Liu X, Hede S, Nadkarni A, Shank T. Gupta K, et al. J Manag Care Spec Pharm. 2018 Nov;24(11):1116-1127. doi: 10.18553/jmcp.2018.17488. Epub 2018 Sep 13. J Manag Care Spec Pharm. 2018. PMID: 30212268 Almutairi AR, Zhou L, Gellad WF, Lee JK, Slack MK, Martin JR, Lo-Ciganic WH. Almutairi AR

The complementary effects of galvanic current electrical stimulation associated with conservative treatment to increase vasodilation in patients with Raynaud`s phenomenon: a randomized trial The Complementary Effects of Galvanic Current Electrical Stimulation Associated With Conservative Treatment to Increase Vasodilation in Patients With Raynaud's Phenomenon: A Randomized Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set (...) , Wells GA, Tugwell P, Pope J. Rirash F, et al. Cochrane Database Syst Rev. 2017 Dec 13;12(12):CD000467. doi: 10.1002/14651858.CD000467.pub2. Cochrane Database Syst Rev. 2017. PMID: 29237099 Free PMC article. Review. Ennis H, Anderson ME, Wilkinson J, Herrick AL. Ennis H, et al. Cochrane Database Syst Rev. 2014 Jan 30;(1):CD002069. doi: 10.1002/14651858.CD002069.pub4. Cochrane Database Syst Rev. 2014. PMID: 24482037 Updated. Review. Black CM, Halkier-Sørensen L, Belch JJ, Ullman S, Madhok R, Smit AJ

Effectiveness of a modified comprehensive behavioral intervention for tics for children and adolescents with tourette`s syndrome: A randomized controlled trial Effectiveness of a Modified Comprehensive Behavioral Intervention for Tics for Children and Adolescents With Tourette's Syndrome: A Randomized Controlled Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go (...) intervention for tics; habit reversal training; nursing; support and education; tics. © 2019 John Wiley & Sons Ltd. Similar articles Hall CL, Davies EB, Andrén P, Murphy T, Bennett S, Brown BJ, Brown S, Chamberlain L, Craven MP, Evans A, Glazebrook C, Heyman I, Hunter R, Jones R, Kilgariff J, Marston L, Mataix-Cols D, Murray E, Sanderson C, Serlachius E, Hollis C; ORBIT Trial team.. Hall CL, et al. BMJ Open. 2019 Jan 3;9(1):e027583. doi: 10.1136/bmjopen-2018-027583. BMJ Open. 2019. PMID: 30610027 Free PMC

Outcome in Children With Standard-Risk B-Cell Acute Lymphoblastic Leukemia: Results of Children`s Oncology Group Trial AALL0331 Children's Oncology Group (COG) AALL0331 tested whether intensified postinduction therapy that improves survival in children with high-risk B-cell acute lymphoblastic leukemia (ALL) would also improve outcomes for those with standard-risk (SR) ALL.AALL0331 enrolled 5,377 patients between 2005 and 2010. All patients received a 3-drug induction with dexamethasone

Primary Prevention of Cow's Milk Sensitization and Food Allergy by Avoiding Supplementation With Cow`s Milk Formula at Birth: A Randomized Clinical Trial Cow's milk formula (CMF) is used to supplement breastfeeding (BF) at birth without clear clinical evidence to support the practice.To determine whether avoiding supplementation with CMF at birth can decrease risks of sensitization to cow's milk protein and/or clinical food allergy, including cow's milk allergy (CMA), overall and in subgroups

Effects of vitamin D supplementation on cognitive function and blood Abeta-related biomarkers in older adults with Alzheimer`s disease: a randomised, double-blind, placebo-controlled trial Our study aimed to assess the effect of a 12-month vitamin D supplementation on cognitive function and amyloid beta (Aβ)-related biomarkers in subjects with Alzheimer's disease (AD). METHODS : This was a randomised, double-blind, placebo-controlled trial. 210 AD patients were randomly divided (...) the control group. According to mixed-model analysis, vitamin D group had significant increase in full scale IQ during follow-up period (p<0.001).Daily oral vitamin D supplementation (800 IU/day) for 12 months may improve cognitive function and decrease Aβ-related biomarkers in elderly patients with AD. Larger scale longer term randomised trials of vitamin D are needed.ChiCTR-IIR-16009549.© Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Cost-effectiveness of laparoscopic ileocaecal resection versus infliximab treatment of terminal ileitis in Crohn`s disease: the LIR!C Trial Evaluate the cost-effectiveness of laparoscopic ileocaecal resection compared with infliximab in patients with ileocaecal Crohn's disease failing conventional therapy.A multicentre randomised controlled trial was performed in 29 centres in The Netherlands and the UK. Adult patients with Crohn's disease of the terminal ileum who failed >3 months (...) ). The probability of resection being cost-effective compared with infliximab was 0.96 at a willingness to pay (WTP) of €0 per QALY gained and per point improvement in IBDQ Score. This probability increased to 0.98 at a WTP of €20 000/QALY gained and 0.99 at a WTP of €500/point of improvement in IBDQ Score.Laparoscopic ileocaecal resection is a cost-effective treatment option compared with infliximab.Dutch Trial Registry NTR1150; EudraCT number 2007-005042-20 (closed on 14 October 2015).© Author(s

Randomized clinical trial of open suture repair versus totally extraperitoneal repair for treatment of sportsman`s hernia Sportsman's hernia/athletic pubalgia is a recognized cause of chronic groin pain in athletes. Both open and laparoscopic surgical repairs have been described for treatment, but there are no comparative studies. The hypothesis here was that relief of pain would be achieved earlier in patients treated with open minimal suture repair than totally extraperitoneal repair.A

Health-related quality of life and costs in Sjogren`s syndrome Health-related quality of life (HRQoL) has an increasing role in medical decision-making. This review of the literature aims to provide an overview on HRQoL, costs, and work disability in SS, a disease characterized by focal lymphocytic infiltration of exocrine glands with no therapeutics of proven immunomodulatory potential. HRQoL is markedly reduced in SS in multiple studies across many countries when compared with HRQoL (...) -blind, placebo-controlled randomized controlled trial. Although primary SS does not, in general, impair life expectancy and is often inappropriately considered a benign 'nuisanvce' disease for those patients without systemic manifestations, the associated costs and work disability are striking. This, together with the significant reduction in HRQoL, strongly argues for the development of new therapeutic approaches to manage this neglected disease.© The Author(s) 2019. Published by Oxford University

A randomized controlled trial of Dilapan-S vs Foley balloon for preinduction cervical ripening (DILAFOL trial) The objective of the study was to test the hypothesis that Dilapan-S is not inferior to the Foley balloon for preinduction cervical ripening at term.Pregnant women ≥37 weeks scheduled for induction with unfavorable cervix (≤3 cm dilated and ≤60% effaced) were randomly assigned to 12 hours of either Foley balloon inflated with 60 mL saline or Dilapan-S for cervical ripening (...) balloon; 210 to Dilapan-S). In the intent-to-treat analysis, vaginal delivery was more common in Dilapan-S vs Foley balloon (81.3% vs 76.1%), with an absolute difference with respect to the Foley balloon of 5.2% (95% confidence interval, -2.7% to 13.0%) indicating noninferiority for the prespecified margin. The difference was not large enough to show superiority. Noninferiority was confirmed in the per-protocol population (n = 204 in the Foley balloon, n = 188 in Dilapan-S), supporting the robustness

Bidirectional relationship between systemic lupus erythematosus and non-Hodgkin`s lymphoma: a nationwide population-based study We conducted this nationwide population-based study in Taiwan to investigate whether there is a bidirectional relationship between SLE and non-Hodgkin's lymphoma (NHL).Using the National Health Insurance Research Database of Taiwan, we identified 16 417 patients with new-onset SLE without previous cancer and 25 069 patients with new-onset NHL without previous SLE (...) , 95% CI 1.1, 3.4). The SIRs of the patients with SLE to develop NHL and the patients with NHL to develop SLE were both highest within the first year after the diagnosis of each disease.This nationwide population-based study is the first study to report a bidirectional relationship between SLE and NHL. This finding may suggest being alert for the patients with SLE or NHL who have early sings of the other disease in clinical care.© The Author(s) 2019. Published by Oxford University Press on behalf

Rituxumab (MabThera) - in combination with glucocorticoids, for the treatment of adult patients with severe, active granulomatosis with polyangiitis (Wegener?s) (GPA) and microscopic polyangiitis (MPA) Published 11 March 2019 Statement of advice SMC2165 rituxumab 100mg, 500mg solution for infusion (MabThera®) Roche Products Ltd 8 February 2019 ADVICE: in the absence of a submission from the holder of the marketing authorisation rituxumab (MabThera®) is not recommended for use within NHSScotland

Metformin?s role in type 1 diabetes: the removal trial Metformin’s Role in Type 1 Diabetes: the REMOVAL Trial – Clinical Correlations Search Metformin’s Role in Type 1 Diabetes: the REMOVAL Trial February 14, 2019 5 min read By William Plowe Peer Reviewed Metformin has been the first-line drug in type 2 diabetes for over a decade, but its possible benefit in type 1 diabetes (DM1) is still a matter of study. The American Diabetes Association lists metformin as an investigational agent that may (...) prevalence of overweight children and adolescents at onset of insulin-treated diabetes. Diabetes Care. 2003;26(10):2871-2875. Wulffelé MG, Kooy A, Lehert P, et al. Combination of insulin and metformin in the treatment of type 2 diabetes. Diabetes Care. 2002;25(12):2133-2140. Action to Control Cardiovascular Risk in Diabetes Study Group, Gerstein HC, Miller ME, Byington RP, et al. Effects of intensive glucose lowering in type 2 diabetes. N Engl J Med . 2008;358(24):2545-2559. Patel A, Macmahon S, Chalmers

Core IM: 5 pearls on Barrett?s esophagus Core IM: 5 Pearls on Barrett’s Esophagus – Clinical Correlations Search Core IM: 5 Pearls on Barrett’s Esophagus January 30, 2019 3 min read Podcast: | Subscribe: | By Vishal Shah MD, Milna Rufin MD, Marty Fried MD, Shreya P. Trivedi MD || Illustration by Amy Ou MD || Audio Editing by Harit Shah. Quiz yourself on the 5 Pearls we will be covering: What is Barrett’s esophagus? (4:12) Who do we screen for Barrett’s, and why? (8:41) How do we screen (...) . Fletcher J, Wirz A, Henry E, et al. Studies of acid exposure immediately above the gastro-oesophageal junction: Evidence of short segment reflux. Gut 2004; 53:168-73. Hayeck T.J., Kong C.Y., Spechler S.J., Gazelle G.S., Hur C. The prevalence of Barrett’s esophagus in the US: estimates from a simulation model confirmed by SEER data. Dis Esophagus. 2010;23:451–457. Rastogi A, Puli S, El-Serag HB et al. Incidence of esophageal adenocarcinoma in patients with Barrett’s esophagus and high-grade dysplasia

Path Finder for freezing of gait in people with Parkinson?s disease P Path Finder for freezing of gait in people with ath Finder for freezing of gait in people with P Parkinson arkinson’s disease ’s disease Medtech innovation briefing Published: 25 January 2019 nice.org.uk/guidance/mib170 pathways Summary Summary The technology technology described in this briefing is Path Finder laser shoe attachment. It is used as a walking aid and is designed to help prevent freezing of gait in people (...) of gait, done in a controlled gait laboratory in the Netherlands. Intervention and comparator(s) Intervention: Path Finder laser shoe. No comparator. Path Finder for freezing of gait in people with Parkinson’s disease (MIB170) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 5 of 11Key outcomes 2 patients were excluded from the analysis; 1 for inability to see the laser and 1 because freezing of gait episodes could

There?s Pus About, So Are Antibiotics In or Out? Adding antibiotics for abscess management Tools for Practice is proudly sponsored by the Alberta College of Family Physicians (ACFP). ACFP is a provincial, professional voluntary organization, representing more than 5,000 family physicians, family medicine residents, and medical students in Alberta. Established over sixty years ago, the ACFP strives for excellence in family practice through advocacy, continuing medical education and primary care

Safety and efficacy of CVT-301 (levodopa inhalation powder) on motor function during off periods in patients with Parkinson`s disease: a randomised, double-blind, placebo-controlled phase 3 trial Patients with Parkinson's disease chronically treated with levodopa commonly have delayed or unpredictable onset of its benefits after oral intake. In this study, we assessed the safety and efficacy of CVT-301, a self-administered levodopa oral inhalation powder, for the treatment of patients

Clinical evaluation of education relating to nutrition and skeletal loading in competitive male road cyclists at risk of relative energy deficiency in sports (RED-S): 6-month randomised controlled trial. To clinically evaluate education to improve eating behaviour and skeletal loading exercise in male cyclists at risk of poor bone health and impaired performance due to relative energy deficiency in sports.Early race season, 50 competitive male road cyclists were matched, in pairs, based on Z

Physiotherapy versus physiotherapy plus cognitive training on cognition and quality of life in Parkinson´s disease: randomized clinical trial. Verify the effectiveness of physiotherapy associated with cognitive training to improve cognition and quality of life in individuals with Parkinson's disease (PD).randomized clinical trial involving 58 individuals with mild to moderate PD, randomly distributed into two groups: motor group (MG) and cognitive-motor group (CMG). Both groups were assessed