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Top results for Anaphylaxis

2. Association Between Intravenous Thrombolysis and Anaphylaxis Among Medicare Beneficiaries With Acute Ischemic Stroke (Abstract)

code 99.10). Our primary outcome was anaphylaxis, defined using an accepted International Classification of Diseases, Ninth Revision, Clinical Modification code algorithm (989.5, 995.0-4, 995.6x, E905, E905.3, E905.5, or E905.8-9). A secondary outcome was anaphylactic shock (995.0 or 995.6x). Multiple logistic regression was used to evaluate the association between intravenous thrombolysis and anaphylaxis after adjustment for demographics, vascular risk factors, the Charlson comorbidity index (...) thrombolysis versus 45 (0.07%; 95% CI, 0.05%-0.09%) who did not. After adjustment for demographics, comorbidities, contrast dye, mechanical thrombectomy, and history of allergies, there was a significant association between receipt of intravenous thrombolysis and anaphylaxis (odds ratio, 7.8; 95% CI, 4.3-13.9). We found a similar association for anaphylactic shock. Conclusions- Although a rare occurrence, the risk of anaphylaxis among patients with acute ischemic stroke was significantly higher among those

2019 EvidenceUpdates

3. ASCIA Guidelines - Acute management of anaphylaxis

ASCIA Guidelines - Acute management of anaphylaxis 1 Acute Management of Anaphylaxis These guidelines are intended for medical practitioners and nurses providing first responder emergency care. The appendix includes additional information for emergency department staff, ambulance staff, rural or remote medical practitioners and nurses providing emergency care. Anaphylaxis definitions • Any acute onset illness with typical skin features (urticarial rash or erythema/flushing, and/or angioedema (...) ), PLUS involvement of respiratory and/or cardiovascular and/or persistent severe gastrointestinal symptoms; or • Any acute onset of hypotension or bronchospasm or upper airway obstruction where anaphylaxis is considered possible, even if typical skin features are not present. The most common triggers of anaphylaxis (severe allergic reaction) are foods, insect stings and drugs (medications). Signs and symptoms of allergic reactions Mild or moderate reactions • Swelling of lips, face, eyes • Hives

2019 Australasian Society of Clinical Immunology and Allergy

4. Perioperative Anaphylaxis Management Guidelines

Immunol 2011; 21:442-453. From: http://www.jiaci.org/issues/vol21issue6/2.pdf Accessed 1 December 2015 10. Association Anaesthetists of Great Britain and Ireland. Suspected anaphylactic reaction associated with anaesthesia. Anaesthesia 2009; 64: 199-211. From: http://www.aagbi.org/sites/default/files/anaphylaxis_2009.pdf Accessed 1 December 2015 11. Rose M, Fisher M. Anaphylaxis and Anaesthesia. What can we do better? Australasian Anaesthesia 2009: 115-119. From: http://www.anzca.edu.au/resources (...) Perioperative Anaphylaxis Management Guidelines Page 1 Guidelines Anaphylaxis 2016 Australian and New Zealand College of Anaesthetists (ANZCA) and Australian and New Zealand Anaesthetic Allergy Group (ANZAAG) Perioperative Anaphylaxis Management Guidelines INTRODUCTON Anaphylaxis is a life-threatening emergency that requires prompt recognition of signs and symptoms, early administration of adrenaline (epinephrine) in adequate dosage, and aggressive volume replacement. Due to the paucity

2019 Australian and New Zealand College of Anaesthetists

5. Anaphylaxis

Anaphylaxis Anaphylaxis - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Anaphylaxis Last reviewed: February 2019 Last updated: March 2019 Summary Sudden onset of respiratory or cardiovascular compromise, usually with a history of allergen exposure in sensitised individuals. Skin rash, wheezing and inspiratory stridor, hypotension, anxiety, nausea, and vomiting are the cardinal signs and symptoms. The diagnosis (...) is clinical. Allergy testing is helpful only for secondary prophylaxis. Securing the airway and initiating prompt treatment with epinephrine (adrenaline) may save lives. Comorbidities (e.g., coronary artery disease and COPD) may pose a treatment challenge and warrant expert consultation Definition Anaphylaxis is an acute, severe, life-threatening allergic reaction in pre-sensitised individuals, leading to a systemic response caused by the release of immune and inflammatory mediators from basophils

2019 BMJ Best Practice

6. Anaphylaxis

Anaphylaxis Printed copies of this document may not be up to date, obtain the most recent version from www.cats.nhs.uk Children’s Acute Transport Service CATS Clinical Guideline Anaphylaxis/Latex Allergy Document Control Information Author D Lutman Author Position Consultant Document Owner E Polke Document Owner Position Service Coordinator Document Version Version 4 Replaces Version Version 3 First Introduced Review Schedule 2 Yearly Active Date January 2016 Next Review January 2020 CATS (...) anaphylaxis and suggest precautions to prevent allergic reactions in a patient suspected of latex allergy. 1. Assessment 1.1 Anaphylaxis is likely when all of the following 3 criteria are met: • Sudden onset and rapid progression of symptoms • Life-threatening Airway and/or Breathing and/or Circulation problems • Skin and/or mucosal changes (flushing, urticarial, angioedema) 1.2 A history of exposure to an allergen supports the diagnosis but is not essential. 1.3 Anaphylaxis should be suspected when

2018 Children's Acute Transport Service

7. Anaphylaxis

Anaphylaxis Anaphylaxis - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Anaphylaxis Last reviewed: February 2019 Last updated: March 2019 Summary Sudden onset of respiratory or cardiovascular compromise, usually with a history of allergen exposure in sensitised individuals. Skin rash, wheezing and inspiratory stridor, hypotension, anxiety, nausea, and vomiting are the cardinal signs and symptoms. The diagnosis (...) is clinical. Allergy testing is helpful only for secondary prophylaxis. Securing the airway and initiating prompt treatment with epinephrine (adrenaline) may save lives. Comorbidities (e.g., coronary artery disease and COPD) may pose a treatment challenge and warrant expert consultation Definition Anaphylaxis is an acute, severe, life-threatening allergic reaction in pre-sensitised individuals, leading to a systemic response caused by the release of immune and inflammatory mediators from basophils

2018 BMJ Best Practice

8. Angio-oedema and anaphylaxis

includes recommendations from the National Institute for Health and Care Excellence (NICE) guidance Anaphylaxis: assessment to confirm an anaphylactic episode and the decision to refer after emergency treatment for a suspected anaphylactic episode . In addition, the management section has been restructured to improve clarity and navigation. Issued in January 2012. February 2011 — technical update. The Management section of this topic has been simplified to improve clarity and navigation. There have (...) been no changes to the clinical content or meaning of the recommendations. September 2008 — minor correction to the Changes section. Issued in September 2008. April 2008 — minor update to include recommendations from the Working Group of the Resuscitation Council (UK) guideline Emergency treatment of anaphylactic reactions: Guidelines for healthcare providers (January 2008). This includes changes in the dosages of emergency drugs for anaphylaxis. Issued in May 2008. January to April 2007

2018 NICE Clinical Knowledge Summaries

9. CRACKCast E119 – Allergy, Hypersensitivity, Angioedema, and Anaphylaxis

anaphylactic reactions. NON-IMMUNOLOGIC MECHANISMS (DIRECT MAST CELL ACTIVATIONS) Physical factors: Exercise, cold, heat, sunlight Ethanol Medications: Some opioids IDIOPATHIC (NO APPARENT TRIGGER) VARIABLE NUMBER OF POTENTIAL TRIGGERS [3] List 6 mediators of anaphylaxis and their physiologic actions and clinical manifestations Refer to table 109.1 in Rosen’s 9 th Edition for the table summarized below describing mediators of anaphylaxis and their physiologic action Here are a couple familiar mediators (...) enzyme (ACE) inhibitors Concurrent use of cognition-impairing drugs (e.g., alcohol, recreational drugs, sedatives, tranquilizers) Recent anaphylaxis episode [6] Describe a standard treatment protocol for patients with a history of radiocontrast-induced anaphylaxis Refer to box 109.4 in Rosen’s 9 th Edition for the summary of a standard protocol for patients with a history of radiocontrast–induced anaphylaxis The pathophysiologic mechanism of anaphylactic reactions to RCM is unknown

2017 CandiEM

10. Drug‐induced anaphylaxis in the emergency room Full Text available with Trip Pro

Drug‐induced anaphylaxis in the emergency room Anaphylaxis is a life-threatening, systemic allergic reaction that presents unique challenges for emergency care practitioners. Anaphylaxis occurs more frequently than previously believed. Therefore, proper knowledge regarding the epidemiology, mechanisms, symptoms, diagnosis, and treatment of anaphylaxis is essential. In particular, the initial treatment strategy, followed by correct diagnosis, in the emergency room is critical for preventing (...) fatal anaphylaxis, although making a diagnosis is not easy because of the broad and often atypical presentation of anaphylaxis. To this end, the clinical criteria proposed by the National Institute of Allergy and Infectious Diseases and the Food Allergy and Anaphylaxis Network are useful, which, together with a differential diagnosis, could enable a more accurate diagnosis. Additional in vitro tests, such as plasma histamine and tryptase measurements, are also helpful. It should be emphasized

2017 Acute medicine & surgery

12. ASCIA Checklist - Travel for people with allergy, asthma and anaphylaxis

ASCIA Checklist - Travel for people with allergy, asthma and anaphylaxis ASCIA Travel Plan: Anaphylaxis - Australasian Society of Clinical Immunology and Allergy (ASCIA) | | ASCIA Travel Plan: Anaphylaxis Other travel information for people at risk of anaphylaxis is available from Allergy & Anaphylaxis Australia: Page updated January 2019 Site last updated: 6 Nov 2019 Member Login Remember Me Log in ASCIA Update Information for the community about allergic diseases, immunodeficiencies and other

2017 Australasian Society of Clinical Immunology and Allergy

13. Management of maternal anaphylaxis in pregnancy: a case report Full Text available with Trip Pro

Management of maternal anaphylaxis in pregnancy: a case report A 26-year-old woman (gravida 2, para 1) at 25 weeks' gestation was brought to the emergency department because of anaphylactic symptoms. She reported eating Japanese soba and developed symptoms of dyspnea, generalized itchy rash, abdominal pain, and severe uterine contractions within 15-30 min of eating. She was immediately treated by normal saline infusion, two injections of epinephrine (intramuscularly), and a nebulized short (...) -acting β2-receptor agonist, followed by H1-antihistamine and methylprednisolone. Obstetrical management was undertaken by an obstetrician.The patient recovered rapidly without a biphasic reaction of anaphylaxis. After 11 weeks, a healthy, neurologically intact baby was born.Management of anaphylaxis in pregnant patients is basically the same of that in non-pregnant ones. Treatment should commence immediately to prevent further development of the anaphylaxis reaction and fetal neurological deficiency.

2016 Acute medicine & surgery

14. Anaphylaxis ? First Aid Management

Anaphylaxis ? First Aid Management ANZCOR Guideline 9.2.7 August 2016 Page 1 of 3 ANZCOR Guideline 9.2.7 – First Aid Management of Anaphylaxis Guideline Who does this guideline apply to? This guideline applies to adults, children and infant victims. Who is the audience for this guideline? This guideline is for use by bystanders, first aiders and first aid providers. 1 Introduction Anaphylaxis is the most severe form of allergic reaction and is potentially life threatening. It must be treated (...) as a medical emergency, requiring immediate treatment and urgent medical attention. Anaphylaxis is a generalised allergic reaction, which often involves more than one body system. A severe allergic reaction usually occurs within 20 minutes of exposure to the trigger. 1 Severe allergic reactions may occur without prior exposure to a trigger. It is characterised by rapidly developing airway and/or breathing and/or circulation problems usually associated with swelling, redness or itching of the skin, eyes

2016 Australian Resuscitation Council

16. ASCIA Clinical Update - Anaphylaxis

resources and phone assistance throughout Australia Allergy New Zealand www.allergy.org.nz Provides patient resources and phone assistance throughout New Zealand ASCIA INFORMATION FOR HEALTH PROFESSIONALS 12 References 1. Loh R, Mullins R, Vale S. Anaphylaxis: Investigating and managing an allergic emergency. Medicine Today 2012; 13 (9):16-25. 2. Sampson et al. Fatal and near fatal anaphylactic reactions to food in children and adolescents. New England Journal of Medicine 1992; 327 (6): 380-4. 3. Brown (...) notes 2007. 8. Stuckey M, Cobain T, Sears M, et al. Bee venom hypersensitivity in Busselton [letter]. Lancet 1982; 2: 41. 9. Thong B, Tan T. Epidemiology and risk factors for drug allergy. Br J Clin Pharmacol 2011; 71 (5): 684- 700. 10. Liew WK, Williamson E, Tang MLK. Anaphylaxis fatalities and admissions in Australia. JACI 2008; 123 (2): 434-42. 11. Bock SA. Fatal Anaphylaxis. UpToDate. 2010. 12. Bock SA. Further fatalities, caused by anaphylactic reactions to food, 2001-2006. JACI 2007; 119 (4

2016 Australasian Society of Clinical Immunology and Allergy

17. Comparative Risk of Anaphylactic Reactions Associated With Intravenous Iron Products. Full Text available with Trip Pro

Comparative Risk of Anaphylactic Reactions Associated With Intravenous Iron Products. All intravenous (IV) iron products are associated with anaphylaxis, but the comparative safety of each product has not been well established.To compare the risk of anaphylaxis among marketed IV iron products.Retrospective new user cohort study of IV iron recipients (n = 688,183) enrolled in the US fee-for-service Medicare program from January 2003 to December 2013. Analyses involving ferumoxytol were limited (...) to the period January 2010 to December 2013.Administrations of IV iron dextran, gluconate, sucrose, or ferumoxytol as reported in outpatient Medicare claims data.Anaphylaxis was identified using a prespecified and validated algorithm defined with standard diagnosis and procedure codes and applied to both inpatient and outpatient Medicare claims. The absolute and relative risks of anaphylaxis were estimated, adjusting for imbalances among treatment groups.A total of 274 anaphylaxis cases were identified

2015 JAMA

18. ASCIA Checklists - Anaphylaxis

ASCIA Checklists - Anaphylaxis Anaphylaxis Checklist for GPs - Australasian Society of Clinical Immunology and Allergy (ASCIA) | | Anaphylaxis Checklist for GPs Anaphylaxis Checklist for General Practice This checklist has been developed to assist General Practitioners optimise the management of patients with severe allergies who are at risk of anaphylaxis. Record history of the allergic reaction, suspected triggers and assess severity (e.g. using ASCIA anaphylaxis event record). Prescribe (...) initial adrenaline autoinjector for newly diagnosed patient and if necessary contact a specialist (allergy, respiratory, paediatrician) for authority prescription, pending specialist appointment. Refer to allergy specialist and provide relevant clinical history. Check adrenaline autoinjector expiry, renew prescription and check that the dose is appropriate for their weight/age : 10-20kg - 0.15mg device; Over 20kg - 0.30mg device. Complete and sign ASCIA Action Plan for Anaphylaxis. Complete and sign

2015 Australasian Society of Clinical Immunology and Allergy

19. ASCIA Guidelines - Prevention of anaphylaxis in schools, pre-schools and childcare: 2015 update

extensive consultation with Allergy & Anaphylaxis Australia and have been adapted and updated based on the ASCIA Guidelines for Prevention of Food Anaphylactic Reactions in Schools, Preschools and Childcare published in December 2004 in the Journal of Paediat- rics and Child Health,Volume40,Issue12,page669andupdated version, ASCIA Prevention of Anaphylaxis in Schools, Pre- schools and Childcare: 2012 update, published in the Journal of Paediatrics and Child Health, Volume 49 (2013) 342–345. References 1 (...) ASCIA Guidelines - Prevention of anaphylaxis in schools, pre-schools and childcare: 2015 update POSITION PAPER ASCIA guidelines for prevention of anaphylaxis in schools, pre-schools and childcare: 2015 update Sandra Vale, 1 Jill Smith, 1 Maria Said, 2,3 Raymond James Mullins 2,4,5 and Richard Loh 2,6 1 Australasian Society of Clinical Immunology and Allergy (ASCIA), 2 ASCIA Anaphylaxis Working Party, 3 Allergy & Anaphylaxis Australia, Sydney, New South Wales, 4 Health Sciences, University

2015 Australasian Society of Clinical Immunology and Allergy

20. Anaphylaxis in Seniors Receiving Intravenous Antibiotics in Long-Term Care: Clinical Evidence and Guidelines

Anaphylaxis in Seniors Receiving Intravenous Antibiotics in Long-Term Care: Clinical Evidence and Guidelines TITLE: Anaphylaxis in Seniors Receiving Intravenous Antibiotics in Long-Term Care: Clinical Evidence and Guidelines DATE: 30 October 2013 RESEARCH QUESTIONS 1. What is the clinical evidence regarding the occurrence of anaphylaxis in seniors receiving IV antibiotics for common acute infections in long-term care? 2. What are the evidence-based the guidelines regarding monitoring (...) and administration of IV antibiotics to seniors with common acute infections in long-term care? KEY MESSAGE No relevant technology assessment reports, systematic reviews, meta-analyses, randomized controlled trials, non-randomized studies, or evidence-based guidelines regarding the occurrence of anaphylaxis in seniors in long term care receiving IV antibiotics or the guidelines for their use were identified. METHODS A limited literature search was conducted on key resources including PubMed, Medline

2013 Canadian Agency for Drugs and Technologies in Health - Rapid Review