Latest & greatest articles for Adenomyosis

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Top results for Adenomyosis

81. ARID1A mutations in endometriosis-associated ovarian carcinomas. Full Text available with Trip Pro

ARID1A mutations in endometriosis-associated ovarian carcinomas. Ovarian clear-cell and endometrioid carcinomas may arise from endometriosis, but the molecular events involved in this transformation have not been described.We sequenced the whole transcriptomes of 18 ovarian clear-cell carcinomas and 1 ovarian clear-cell carcinoma cell line and found somatic mutations in ARID1A (the AT-rich interactive domain 1A [SWI-like] gene) in 6 of the samples. ARID1A encodes BAF250a, a key component (...) of the BAF250a protein correlated strongly with the ovarian clear-cell carcinoma and endometrioid carcinoma subtypes and the presence of ARID1A mutations. In two patients, ARID1A mutations and loss of BAF250a expression were evident in the tumor and contiguous atypical endometriosis but not in distant endometriotic lesions.These data implicate ARID1A as a tumor-suppressor gene frequently disrupted in ovarian clear-cell and endometrioid carcinomas. Since ARID1A mutation and loss of BAF250a can be seen

2010 NEJM

83. Anti-TNF-alpha treatment for pelvic pain associated with endometriosis. (Abstract)

Anti-TNF-alpha treatment for pelvic pain associated with endometriosis. Endometriosis is a chronic, recurring condition that can develop during the reproductive years. It is characterized by the development of endometrial tissue outside the uterine cavity. It is the most common cause of pelvic pain in women. This endometrial tissue development is dependent on estrogen produced primarily by the ovaries and, therefore, traditional management has focused on suppression of ovarian function (...) . The mounting evidence shows that altered immune function plays a crucial role in the genesis and development of endometriosis. In this review we considered modulating the inflammation as an alternative approach.To determine the effectiveness and safety of anti-tumour necrosis factor-alpha (anti-TNF-alpha) drugs in the management of pelvic pain associated with endometriosis.We searched for trials in the following databases (from their inception to August 2009): Cochrane Menstrual Disorders and Subfertility

2010 Cochrane

84. Endometriosis: Diagnosis and Management

Endometriosis: Diagnosis and Management Endometriosis: Diagnosis and Management - Journal of Obstetrics and Gynaecology Canada Email/Username: Password: Remember me Search Terms Search within Search Volume 32, Issue 7, Supplement 2, Pages S1–S3 Endometriosis: Diagnosis and Management PRINCIPAL AUTHORS, x Nicholas Leyland , MD Toronto ON x Robert Casper , MD Toronto ON x Philippe Laberge , MD Quebec QC x Sukhbir S. Singh , MD Ottawa ON SPECIAL CONTRIBUTORS, x Lisa Allen , MD Toronto ON x (...) Lynn Wolfman , MD Toronto ON x Vyta Senikas , MD Ottawa, ON DOI: To view the full text, please login as a subscribed user or . Click to view the full text on ScienceDirect. Abstract Objective To improve the understanding of endometriosis and to provide evidence-based guidelines for the diagnosis and management of endometriosis. Outcomes Outcomes evaluated include the impact of the medical and surgical management of endometriosis on women’s experience of morbidity and infertility. Methods Members

2010 Society of Obstetricians and Gynaecologists of Canada

85. Medical Management of Pain Associated With Endometriosis

Medical Management of Pain Associated With Endometriosis Medical Management of Pain Associated With Endometriosis - Journal of Obstetrics and Gynaecology Canada Email/Username: Password: Remember me Search Terms Search within Search Volume 32, Issue 7, Supplement 2, Pages S9–S14 Medical Management of Pain Associated With Endometriosis DOI: To view the full text, please login as a subscribed user or . Click to view the full text on ScienceDirect. To access this article, please choose from

2010 Society of Obstetricians and Gynaecologists of Canada

86. Surgical Management of Endometriosis

Surgical Management of Endometriosis Surgical Management of Endometriosis - Journal of Obstetrics and Gynaecology Canada Email/Username: Password: Remember me Search Terms Search within Search Volume 32, Issue 7, Supplement 2, Pages S15–S18 Surgical Management of Endometriosis DOI: To view the full text, please login as a subscribed user or . Click to view the full text on ScienceDirect. To access this article, please choose from the options below Log In Register Purchase access to this article

2010 Society of Obstetricians and Gynaecologists of Canada

87. Surgical Management of Infertility Associated With Endometriosis

Surgical Management of Infertility Associated With Endometriosis Surgical Management of Infertility Associated With Endometriosis - Journal of Obstetrics and Gynaecology Canada Email/Username: Password: Remember me Search Terms Search within Search Volume 32, Issue 7, Supplement 2, Pages S19–S20 Surgical Management of Infertility Associated With Endometriosis DOI: To view the full text, please login as a subscribed user or . Click to view the full text on ScienceDirect. To access this article

2010 Society of Obstetricians and Gynaecologists of Canada

88. Endometriosis in Adolescents Full Text available with Trip Pro

Endometriosis in Adolescents Endometriosis in Adolescents - Journal of Obstetrics and Gynaecology Canada Email/Username: Password: Remember me Search Terms Search within Search Volume 32, Issue 7, Supplement 2, Pages S23–S25 Endometriosis in Adolescents DOI: To view the full text, please login as a subscribed user or . Click to view the full text on ScienceDirect. To access this article, please choose from the options below Log In Register Purchase access to this article Claim Access If you

2010 Society of Obstetricians and Gynaecologists of Canada

89. Medical Treatment of Infertility Related to Endometriosis

Medical Treatment of Infertility Related to Endometriosis Medical Treatment of Infertility Related to Endometriosis - Journal of Obstetrics and Gynaecology Canada Email/Username: Password: Remember me Search Terms Search within Search Volume 32, Issue 7, Supplement 2, Pages S21–S22 Medical Treatment of Infertility Related to Endometriosis DOI: To view the full text, please login as a subscribed user or . Click to view the full text on ScienceDirect. To access this article, please choose from

2010 Society of Obstetricians and Gynaecologists of Canada

90. Endometriosis and Cancer

Endometriosis and Cancer Endometriosis and Cancer - Journal of Obstetrics and Gynaecology Canada Email/Username: Password: Remember me Search Terms Search within Search Volume 32, Issue 7, Supplement 2, Pages S26–S28 Endometriosis and Cancer DOI: To view the full text, please login as a subscribed user or . Click to view the full text on ScienceDirect. To access this article, please choose from the options below Log In Register Purchase access to this article Claim Access If you are a current

2010 Society of Obstetricians and Gynaecologists of Canada

91. Nonsteroidal anti-inflammatory drugs for pain in women with endometriosis. Full Text available with Trip Pro

Nonsteroidal anti-inflammatory drugs for pain in women with endometriosis. Endometriosis is a common gynaecological condition that affects women and can lead to painful symptoms and infertility. It greatly affects women's quality of life, impacting on their careers, everyday activities, sexual and non-sexual relationships, and fertility. Non-steroidal anti-inflammatory drugs (NSAIDs) are the most commonly used first-line treatment for endometriosis.To assess the effects of NSAIDs used (...) for the management of pain in women with endometriosis compared to placebo, other NSAIDs, other pain management drugs, or no treatment.We searched the Cochrane Menstrual Disorders and Subfertility Group Trials Register (April 2008) published in the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library), MEDLINE (1966 to April 2008), EMBASE (1980 to April 2008), and the reference lists from relevant publications. Experts in the field were also contacted for information about possible

2009 Cochrane

92. Hormone therapy for endometriosis and surgical menopause. (Abstract)

Hormone therapy for endometriosis and surgical menopause. Endometriosis is characterized by the presence of ectopic endometrial tissue that might lead to many distressing and debilitating symptoms. Despite available studies supporting standard hormone therapy for women with endometriosis and post-surgical menopause, there is still a concern that estrogens may induce a recurrence of the disease and its symptoms.This review aimed to look at pain and disease recurrence in women with endometriosis (...) who used hormone therapy for post-surgical menopause.We searched the Cochrane Menstrual Disorders and Subfertility Group Specialized Register (March 2008), Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2008, Issue 3), MEDLINE (1966 to March 2008), EMBASE (1980 to March 2008), and references lists of articles. Relevant journals and conference proceedings were handsearched.Randomized controlled trials studying hormone therapy for women with endometriosis in post

2009 Cochrane

93. Laparoscopic management of endometriosis: comprehensive review of best evidence

Laparoscopic management of endometriosis: comprehensive review of best evidence Laparoscopic management of endometriosis: comprehensive review of best evidence Laparoscopic management of endometriosis: comprehensive review of best evidence Yeung PP, Shwayder J, Pasic RP CRD summary The authors found that laparoscopic treatment of endometriosis reduced pain and improved fertility. Co-interventions that may help (in appropriate circumstances) included laparoscopic presacral neurectomy, pre (...) -operative and/or postoperative hormonal suppression, excisional cystectomy with mesna and/or initial circular excision and anti-adhesive barriers. Due to methodological problems in the review, particularly the failure to assess study quality, the conclusions should be regarded cautiously. Authors' objectives To assess the effectiveness of laparoscopic techniques for pain and/or fertility problems associated with endometriosis. Searching The Cochrane Library and MEDLINE were searched from 1966. Search

2009 DARE.

94. The effect of surgical treatment for endometrioma on in vitro fertilization outcomes: a systematic review and meta-analysis

The effect of surgical treatment for endometrioma on in vitro fertilization outcomes: a systematic review and meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2009 DARE.

95. Medical treatment for rectovaginal endometriosis: what is the evidence? Full Text available with Trip Pro

(limited quality), one RCT (adequate quality) and one patient-preference cohort study (moderate quality). Aromatase inhibitors : Administration of vaginal anastrozole 0.25mg/day for six months (n=9, non-comparative) significantly decreased pain during treatment. Administration of oral letrozole plus progestin (n=12) significantly decreased pain during treatment and improved quality of life. Neither drug influenced endometrial foci size. Gonadotrophin-releasing hormone agonists : Administration (...) Medical treatment for rectovaginal endometriosis: what is the evidence? Medical treatment for rectovaginal endometriosis: what is the evidence? Medical treatment for rectovaginal endometriosis: what is the evidence? Vercellini P, Crosignani PG, Somigliana E, Berlanda N, Barbara G, Fedele L CRD summary The authors concluded that medical treatments of women with rectovaginal endometriosis were effective for pain relief. Given that the studies were limited by size, quality and were heterogeneous

2009 DARE.

96. The effect of second-line surgery on reproductive performance of women with recurrent endometriosis: a systematic review

The effect of second-line surgery on reproductive performance of women with recurrent endometriosis: a systematic review Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2009 DARE.

97. [Evaluation of pain and depression in women with endometriosis after a multi- professional group intervention]. (Abstract)

[Evaluation of pain and depression in women with endometriosis after a multi- professional group intervention]. Evaluate pain and depression scores before and after multi-professional group intervention in women with endometriosis as compared to those who did not participate in this activity.A total of 128 women attended at the Endometriosis Outpatient Facility CAISM/UNICAMP, was assessed and distributed equally into two groups: women who received group intervention and those who did not. All (...) pain and depression in women with endometriosis and may be included in the conventional treatment for patients affected by this disease.

2007 Revista da Associacao Medica Brasileira (1992)

98. Danazol for pelvic pain associated with endometriosis. (Abstract)

Danazol for pelvic pain associated with endometriosis. Endometriosis is defined as the presence of endometrial tissue (stromal and glandular) outside the normal uterine cavity. Conventional medical and surgical treatments for endometriosis aim to remove or decrease the deposits of ectopic endometrium. The observation that hyper androgenic states (an excess of male hormone) induce atrophy of the endometrium has led to the use of androgens in the treatment of endometriosis. Danazol is one (...) of these treatments. The efficacy of danazol is based on its ability to produce a high androgen and low oestrogen environment (a pseudo menopause) which results in atrophy of the endometriotic implants and thus an improvement in painful symptoms.To determine the effectiveness of danazol compared to placebo or no treatment in the treatment of the symptoms and signs, other than infertility, of endometriosis in women of reproductive age.We searched the Cochrane Menstrual Disorders and Subfertility Group Specialised

2007 Cochrane

99. WITHDRAWN: Gonadotrophin-releasing hormone analogues for pain associated with endometriosis. (Abstract)

WITHDRAWN: Gonadotrophin-releasing hormone analogues for pain associated with endometriosis. Endometriosis is a common gynaecological condition that frequently presents with the symptom of pain. The precise pathogenesis (mode of development) of endometriosis is unclear but it is evident that endometriosis arises by the dissemination of endometrium to ectopic sites and the subsequent establishment of deposits of ectopic endometrium. The observation that endometriosis is rarely seen in the hypo (...) to non stimulation of the ovary).To determine the effectiveness of Gonadotrophin Releasing Hormone analogues (GnRHas) in the treatment of the painful symptoms of endometriosis by comparing them with no treatment, placebo, other recognised medical treatments, and surgical interventions.The search strategy of the Menstrual Disorders and Subfertility review group (please see Review Group details) was used to identify all randomised trials of the use of GnRHas for the treatment of the painful symptoms

2007 Cochrane

100. Oral contraceptives for pain associated with endometriosis. Full Text available with Trip Pro

Oral contraceptives for pain associated with endometriosis. Endometriosis is a common gynaecological condition which affects many women of reproductive age worldwide and is a major cause of pain and infertility. The modern oral contraceptive pill is widely used to treat pain occurring as a result of endometriosis, although the evidence for its efficacy is limited.To assess the effects of the oral contraceptive pill (OCP) in comparison to other treatments for painful symptoms of endometriosis (...) to the diagnosis of endometriosis and made visually at surgical procedure were included.Study quality assessment and data extraction were carried out independently by two review authors. One of the assessors was an expert in the content matter. We contacted study authors for additional information.Only one study met the inclusion criteria, in which a total of 57 women were allocated to two groups to compare an OCP to a GnRH analogue. Methods of randomisation and allocation concealment were unclear

2007 Cochrane