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1. Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease

by patient, clinical and procedural characteristics. The benefit of DAPT for reduction in ischemic risk must be weighed against the risk of bleeding from its extended use. This document summarizes recent changes in clinical practice guidelines. EFFICACY OF DUAL ANTIPLATELET THERAPY The use of acetylsalicylic acid (ASA) in combination with either clopidogrel, ticagrelor, or prasugrel is indicated for the treatment of ACS to prevent future major adverse cardiovascular events (MACE). The use of ASA (...) in combination with clopidogrel, ticagrelor or prasugrel is indicated following emergent PCI for the treatment of ACS, and the use of ASA with clopidogrel is indicated following elective PCI for the treatment of chronic stable angina. DAPT in those with ACS who underwent revascularization • The PCI-CURE study initially established the benefit of DAPT (clopidogrel with ASA) over ASA alone in patients who underwent PCI for Non-ST Elevation Acute Coronary Syndrome (NSTEACS). • The PLATO trial (ticagrelor

2021 Thrombosis Interest Group of Canada

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