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Speech Language Pathology

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281. Standards and Guidelines for Validating Next-Generation Sequencing Bioinformatics Pipelines Full Text available with Trip Pro

Pathology and the College of American Pathologists x Somak Roy Affiliations Next Generation Sequencing Bioinformatics Pipeline Validation Working Group of the Clinical Practice Committee, Bethesda, Maryland Division of Molecular and Genomic Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania Correspondence Address correspondence to Somak Roy, M.D., Division of Molecular and Genomic Pathology, University of Pittsburgh Medical Center, 3477 Euler Way, Room 7028, Pittsburgh, PA (...) 15213. ∗ , † , ∗ , x Somak Roy Affiliations Next Generation Sequencing Bioinformatics Pipeline Validation Working Group of the Clinical Practice Committee, Bethesda, Maryland Division of Molecular and Genomic Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania Correspondence Address correspondence to Somak Roy, M.D., Division of Molecular and Genomic Pathology, University of Pittsburgh Medical Center, 3477 Euler Way, Room 7028, Pittsburgh, PA 15213. , x Christopher Coldren

2018 Association for Molecular Pathology

282. Knee Pain and Mobility Impairments: Meniscal and Articular Cartilage Lesions

(IKDC 2000) or Knee injury and Osteoarthritis Out- come Score (KOOS) (or a culturally appropriate version for patients whose primary language is not English) and may use the Lysholm scale (with removal of swelling item, and using unweighted scores). C Clinicians may use the T egner scale or Marx activity rating scale to assess activity level before and after interventions intended to alleviate the physical im pairments, activity limitations, and participation restrictions associated with meniscus (...) Cartilage Based on studies of knee arthroscopies, the prevalence of ar- ticular cartilage pathologies is reported to be between 60% and 70%. 8,69 The incidence of isolated articular cartilage le- sions (30%) is lower than that of nonisolated cartilage le- sions. 139 Thirty-two percent to 58% of all articular cartilage lesions are the result of a traumatic, noncontact mechanism of injury. 74,139 Sixty-four percent of all chondral lesions were less than 1 cm 2 . 139 Thirty-three percent to 60% of articu

2018 The Orthopaedic Section of the American Physical Therapy Association (APTA), Inc.

284. The care of the patient with amyotrophic lateral sclerosis: multidisciplinary care, symptom management, and cognitive/behavioral impairment

). Multidisciplinary clinic. Does multidisciplinary management improve outcomes? In specialized multidisciplinary clinics, patients with ALS receive comprehensive care from a physician, physical therapist, occupational therapist, speech pathologist, dietitian, social worker, respiratory therapist, and nurse case manager. Studies suggest varying degrees of adherence to the practice parameters (Class III). Specialized clinics coordinate care and interface with a primary care physician and community-based services (...) , emotional blunting, and loss of insight. These criteria are required for the diagnosis of FTD, which is supported by neuropsychological abnormalities, language dysfunction, and poor self care. ALSci reflects frontotemporal dysfunction with deficits in attention, cognitive flexibility, and word generation, with relative sparing of visuospatial function and memory. ALSbi refers to changes in social interactions unrelated to a psychiatric condition. The domain of cognitive and behavioral impairment in ALS

2009 American Academy of Neurology

285. Evaluation of distal symmetric polyneuropathy: role of autonomic testing, nerve biopsy, and skin biopsy

to the evaluation of DSP, and subcommittees were formed to address each of these questions. DESCRIPTION OF THE ANALYTIC PROCESS The literature search included OVID MEDLINE (1966 to March 2007), OVID Excerpta Medica (EMBASE; 1980 to March 2007), and OVID Current Contents (2000 to March 2007). The search included articles on humans only and in all languages. The search terms selected were peripheral neuropathy, polyneuropathy, and distal symmetric polyneuropathy. These terms were cross-referenced with the terms (...) immunohistochemistry has been validated as a reliable method for IENF density determination with good intra- and interobserver reliability in normal controls and patients with DSP. In March 2005, the European Federation of Neurological Societies (EFNS) published a guideline on the use of skin biopsy in peripheral neuropathy. This comprehensive review focused on the technical aspects of skin biopsy as well as normative data and correlations with other clinical, physiologic, and pathologic tools. The EFNS concluded

2009 American Academy of Neurology

286. Treatment and recommendations for homeless people with with Otitis Media

attachment to parent and emotional and social development. Screen hearing routinely; refer to audiologist/ ENT specialist as needed. • Speech delays – exacerbated by ear infections in homeless children (who may have delayed social and verbal skills unrelated to OM). Refer to speech pathologist as needed. • Lack of transportation – can impede access to specialty care. Help with transportation to needed health services. • Financial barriers – lack of health insurance or resources to make co-payments (...) are susceptible to recurrent ear infections and may also have speech and language disabilities related to effects of HIV virus on the developing central nervous system (Retzlaff, 1999). It is also important to review the patient’s immunization record (delayed immunizations are common among homeless children). This may also help the clinician identify likely pathogens causing AOM. Ask about any medications, herbal or vitamin supplements, or other complementary or alternative therapies the patient has received

2008 National Health Care for the Homeless Council

287. Treatment and recommendations for homeless people with asthma

and where prescriptions were filled. Assess patient mobility and the likelihood of remaining in one place to work on asthma control. • Health insurance – Ask whether patient has prescription drug coverage. • Literacy – Assess patient’s ability to read instructions in English or their primary language. • Reliability – Consider possibility that patient may give unreliable information about a history of asthma to obtain inhalers to sell or to enhance illicit drug effects. • Complexity – Recognize (...) patients apply for SSI/ Medicaid or obtain medications through pharmaceutical discount programs (340B, manufacturer- sponsored patient assistance programs). • Transience – Recognize that patients may seek care from more than one source and may not remain in one area, or may be intermittently incarcerated. • Functional impairments – Evaluate for cognitive deficits secondary to substance use, mental illness, trauma, and/or developmental disability that complicate treatment. • Literacy/ language barriers

2008 National Health Care for the Homeless Council

288. A review of the evidence for the use of telemedicine within stroke systems of care Full Text available with Trip Pro

been used in the evaluation of stroke patients, the NIHSS is generally regarded as the reference standard for stroke clinical deficit scale assessments. The NIHSS is a 13-item graded neurological examination that assesses consciousness, visual field abnormalities, gaze disturbances, motor and sensory abilities, speech and language functions, and inattention. Only a few clinical signs relevant for stroke diagnosis like distal motor function and balance and gait disorders are not covered (...) conducted a comprehensive review of the relevant literature. Although a complete list of key words is beyond the scope of this section, the committee reviewed all compiled reports from computerized searches and conducted additional searching by hand. Searches were limited to English language sources and to human subjects. Literature citations were generally restricted to published manuscripts appearing in journals listed in Index Medicus and reflect literature published as of June 30, 2007, although

2009 American Academy of Neurology

289. Definition and evaluation of transient ischemic attack Full Text available with Trip Pro

. Conclusion The frequency distribution of durations of transiently symptomatic cerebral ischemic events shows no special relationship to the 24-hour time point ( Class III, Level of Evidence A ). Disease definitions in clinical medicine, including those for ischemic injuries, are most useful when tissue based. Evidence Seeking the pathological basis of disease and directing treatment at underlying biological processes are central tenets of modern medicine. Tissue-based definitions are the rule (...) . The California score and the ABCD score both predict short-term risk of stroke well in independent populations of patients presenting acutely after a TIA. The newer ABCD score was derived to provide a more robust prediction standard and incorporates elements from both prior scores. Patients with TIA score points (indicated in parentheses) for each of the following factors: age ≥60 years (1); blood pressure ≥140/90 mm Hg on first evaluation (1); clinical symptoms of focal weakness with the spell (2) or speech

2009 American Academy of Neurology

290. Evaluation and Management of Adult Patients Presenting to the Emergency Department With Acute Headache

has negative ?ndings in both CT and lumbar puncture? Evidence was graded and recommendations were given based on the strength of the available data in the medical literature. INTRODUCTION A query of the National Hospital Ambulatory Medical Care Survey for 1999 to 2001 found that headache accounted for 2.1 million emergency department (ED) visits (2.2 % of all ED visits). Of the 14% of the patients who underwent imaging, 5.5% received a pathologic diagnosis. 1 Emergency physicians must determine (...) -language sources, human studies, adults, and years January 2000 to August 2006. Additional articles were reviewed from the bibliography of articles cited and from published textbooks and review articles. Subcommittee members supplied articles from their own ?les, and more recent articles identi?ed during the expert review process were also included. The reasons for developing clinical policies in emergency medicine and the approaches used in their development have been enumerated. 4 This policy

2008 Congress of Neurological Surgeons

291. Diagnosis of Cushing's Syndrome Full Text available with Trip Pro

of test accuracy to inform the recommendations ( ). The Task Force also used consistent language and graphical descriptions of both the strength of a recommendation and the quality of evidence. In terms of the strength of the recommendation, strong recommendations use the phrase “we recommend” and the number 1, and weak recommendations use the phrase “we suggest” and the number 2. Cross-filled circles indicate the quality of the evidence, such that ⊕○○○ denotes very low-quality evidence; ⊕⊕○○, low (...) and there is not excessive volume. For pediatric patients, the adult normal ranges may be used because most pediatric patients are of adult weight ( i.e . > 45 kg). At the recommended cutoff point, false-positive elevations of UFC may be seen in several conditions. High fluid intake (≥5 liters/d) significantly increases UFC ( ). Any physiological or pathological condition that increases cortisol production raises UFC ( ). Therefore, in these conditions a normal result is more reliable than an abnormal one

2008 The Endocrine Society

292. Practice Parameters for the Use of Actigraphy in the Assessment of Sleep and Sleep Disorders: An Update for 2007

- nolence, but the exact role of actigraphy in interpreting MSLT or assigning diagnoses was not described. The complaint of sleepiness must be evaluated in the context of recent sleep duration and pattern before a judgment can be made as to the pathologic nature of the complaint. The guidelines de- veloped for the MSLT 39 indicate that sleep logs may be obtained for 1 week prior to the PSG/MSLT to assess sleep-wake sched- ules and assist in interpretation of results, while the ICSD-2 indi- cates

2007 American Academy of Sleep Medicine

293. Utility of surgical decompression for treatment of diabetic neuropathy

of diabetes, behind macrovascular disease and nephropathy. Several evidence-based reviews for treatment modalities for DPN are available. Surgical decompression of multiple peripheral nerves is being utilized as an alternative approach to treatment of symptomatic diabetic neuropathy. This is based on the hypothesis that diabetic nerves are more vulnerable to compressive injury at potential sites for entrapment. This forms the “double crush” or “double pathology” hypothesis, a term originally coined (...) for increased susceptibility of nerves with proximal and distal compressive lesions. The metabolic stress of diabetes is the first crush, and compression of the nerve at the potential site of entrapment will cause the second crush. According to this hypothesis, most patients remain asymptomatic despite having diabetic nerve disease. Only when the second pathology occurs (compression of the nerves at entrapment sites) will the patients become symptomatic. Thus it has been hypothesized that symptoms

2006 American Academy of Neurology

294. Diagnosis and prognosis of new onset parkinson disease

prevalence of up to 329/100,000. Although PD is common, it can be difficult to diagnose clinically, particularly in early stages, and approximately 5 to 10% of patients with PD are misdiagnosed. Conversely, up to 20% of patients diagnosed with PD reveal alternative diagnoses at autopsy, such as multiple system atrophy (MSA), progressive supranuclear palsy (PSP), AD-type pathology, and cerebrovascular disease. Based on these studies, diagnostic criteria have been developed, with the most commonly used (...) identified four articles that addressed the diagnostic accuracy of clinical features that were helpful in differentiating PD from other forms of parkinsonism (table E-1). A Class II case control study of 77 patients with pathologic diagnoses of different parkinsonian conditions including corticobasal degeneration (CBD), dementia with Lewy bodies (DLB), MSA, PD, and PSP revealed that falling within 1 year of diagnosis was a strong predictor of other forms of parkinsonism. Recurrent falling within

2006 American Academy of Neurology

295. Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy Full Text available with Trip Pro

, and Cochrane Central Register of Control Trial via Wiley. All study selection and screening were conducted using the DOC Library software platform (Doctor Evidence). DOC Library is a Web-based platform featuring duplicate removal, keyword emphasis (coloring or bolding of keywords), and search and ranking functionalities and can assign and manage reasons for exclusion. Before screening began, duplicate studies and those that did not meet language or date restrictions were excluded. Screening guidelines (...) review if they were editorials, commentaries, letters, news articles, narrative reviews, or published in a non-English language. The guideline recommendations are crafted, in part, by using the Guidelines Into Decision Support (GLIDES) methodology. In addition, a guideline implementability review was conducted. Based on the implementability review, revisions were made to the draft to clarify recommended actions for clinical practice. Detailed information about the methods used to develop

2018 American Society of Clinical Oncology Guidelines

296. Importance of Social Determinants of Health and Cultural Awareness in the Delivery of Reproductive Health Care

’ abilities to fulfill these needs. Provide access to interpreter services for all patient interactions when patient language is not the clinician’s language. Acknowledge that race, institutionalized racism, and other forms of discrimination serve as social determinants of health. Recognize that stereotyping patients based on presumed cultural beliefs can negatively affect patient interactions, especially when patients’ behaviors are attributed solely to individual choices without recognizing the role (...) website at . Interpreter Services—Language barriers can be partially addressed by having professional interpreters available when the patient’s language is not the clinician’s language (see Committee Opinion No. 587, ). In-person interpretation can enhance interpersonal interactions, but when this is not possible, using a phone service or video interpretation service is a good option with high patient-satisfaction ratings ( ). Transportation and Logistics—Underserved populations often have

2018 American College of Obstetricians and Gynecologists

297. Hoarseness (Dysphonia) Full Text available with Trip Pro

Surgery Foundation selected a panel representing the fields of advanced practice nursing, bronchoesophagology, consumer advocacy, family medicine, geriatric medicine, internal medicine, laryngology, neurology, otolaryngology–head and neck surgery, pediatrics, professional voice, pulmonology, and speech-language pathology. Action Statements The guideline update group made strong recommendations for the following key action statements (KASs): (1) Clinicians should assess the patient with dysphonia (...) . The AAO-HNSF assembled a GUG representing the disciplines of advanced practice nursing, bronchoesophagology, consumer advocacy, family medicine, geriatric medicine, internal medicine, laryngology, neurology, otolaryngology–head and neck surgery, pediatrics, professional voice, pulmonology, and speech-language pathology. The GUG had several conference calls and 1 in-person meeting during which it defined the scope and objectives of updating the guideline, reviewed comments from the expert panel review

2018 American Academy of Otolaryngology - Head and Neck Surgery

298. Exercise-Based Knee and Anterior Cruciate Ligament Injury Prevention Full Text available with Trip Pro

exercises; and other training modalities, but excludes passive interventions such as bracing or programs that only involve education. Knee injuries were defined as any knee joint pathology including damage to the joint (patellofemoral and/or tibiofemoral), ligaments, meniscus, or patellar tendon. The recommendations can be followed and implemented by athletes, coaches, health and fitness professionals, athletic trainers, physical therapists, physicians, surgeons, and other clinicians. The objectives (...) pathology including damage to the joint (patellofemoral and/or tibiofemoral), ligaments, meniscus, or patellar tendon. Articles that focused on preventing knee injuries as a whole were included, but so too were articles focused on only one type of knee injury (eg, anterior cruciate ligament [ACL] injuries or patellofemoral pain). This CPG delineates between evidence related to ACL injuries and all knee injuries. Mechanism of injury included both contact (injuries as a result of collision with another

2018 The Orthopaedic Section of the American Physical Therapy Association (APTA), Inc.

299. Ultrasound Guidelines: Emergency, Point-of-care, and Clinical Ultrasound Guidelines in Medicine

of the guidelines. The ultimate mission of providing excellent patient care will be enhanced by emergency physicians and other clinicians being empowered with the use of US. Section 2 -- Scope of Practice Emergency Ultrasound (EUS) is the medical use of US technology for the bedside evaluation of acute or critical medical conditions. 1 It is utilized for diagnosis of any emergency condition, resuscitation of the acutely ill, critically ill or injured, guidance of procedures, monitoring of certain pathologic (...) in Medicine Page 3 of 46 examination, repeated due to clinical need or deterioration, or used for monitoring of physiologic or pathologic changes. Emergency US is synonymous with the terms clinical, bedside, point-of-care, focused, and physician performed, but is part of a larger field of clinical ultrasonography. In this document, EUS refers to US performed by emergency physicians or clinicians in the emergency setting, while clinical ultrasonography refers to a multidisciplinary field of US use

2016 American College of Emergency Physicians

300. Clinical Practice Guideline for the Behavioral Treatment of Obesity and Overweight in Children and Adolescents

guideline can facilitate decision-making for both provider and patient. How these recommendations compare to recommendations in other obesity guideline documents is addressed on pages 30–31. For definitions of key terms, see Appendix B. People-First Language Throughout the document the panel refers to the target population as “persons with obesity” so as to separate the individual from the condition. 4 Energy-balance behaviors are the caloric intake/ingestive behaviors balanced with the energy (...) al., 2013). Weight stigmatization can take many forms, including teasing, ignoring, excluding, or rejecting the individual; and physical or verbal harassment (Harrist et al., 2016; Schvey, Puhl, & Brownell, 2011). Although childhood obesity has become far more commonplace, weight-based stigmatization remains pervasive (Lumeng et al., 2010). Given the immediate health and psychosocial consequences, as well as the increased long-term health risks in adulthood associated with overweight and obesity

2018 American Psychological Association

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