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101. WHO recommendations on adolescent health

and physical activity Tobacco 8. Violence and injury prevention 9. Prevention of mental health problems and promotion of mental health 10. Nutrition Management of adolescent conditions 11. HIV testing and counselling for adolescents living with HIV 12. Antiretroviral Therapy 13. Treatment of skin and oral HIV-associated conditions in children and adults 14. Treatment of sexually transmitted infections 15. Treatment of malaria 16. Treatment of malnutrition 17. Violence and injuries 18. Mental disorders 36 (...) and social supports. (Indirect evidenced Strong) Source ¦ ¦ Take a complete history, recording events to determine what interventions are appropriate, and conduct a complete physical examination (head-to-toe including genitalia). The history should include: — the time since assault and type of assault — risk of pregnancy risk of HIV and other sexually transmitted infections (STIs) — mental health status. (Indirect evidence Strong) Source Emergency contraception ¦ ¦ Offer emergency contraception

2017 World Health Organisation Guidelines

102. Driving and pain

Doctors Pain doctors should be aware of the circumstances that can lead to impairment of driving: o Physical restrictions that prevent safe performance of driving manoeuvres o The effects of pain on sleep, mood and concentration o The effects of medication • Doctors should inform their patients that most pain medication may impair driving, and that patients should not drive if this is the case. Patients are most at risk of impairment: o When commencing a new pain medicine o When increasing or reducing (...) Safety: A Critical Analysis of Recent Evidence. Road Safety Web Publication No. 21. Department for Transport, 2011. 4. Jones JG, McCann J, Lassere MN. Driving and arthritis. Br J Rheumatol 1991; 30(5): 361-4. 5. Veldhuijzen DS, van Wijck AJM, Wille F, et al. Effect of chronic non malignant pain on highway driving performance. Pain 2006; 122: 28-35 6. Fan A, Wilson KG, Acharya M, et al. Self-Reported Issues With Driving in Patients With Chronic Pain. Physical Medicine and Rehabilitation 2012; 4: 87-95

2017 Faculty of Pain Medicine

103. Clinical Guideline for Administration of Molecular Radiotherapy

Clinical Guideline for Administration of Molecular Radiotherapy 1 Author: Sarah Allen, Margaret Hall, Claire Greaves, John Dickson (on behalf of IPEM SIG) Approved by the British Nuclear Medicine Society Professional Standards Committee 07.06.2017 Report June 2017 Clinical Guideline for Administration of Molecular Radiotherapy 2 Contents …… ……… … ………… ……… ……… … ………… ………2 Purpose ……… ………… ………… ……… ……… … ………… . …… 3 Background ………… … ………… ……… ……… … ………… . . ……3 List of Molecular Radiotherapy (...) Protection Advisor(RPA) Prior risk assessment, compliance with IRR99 (and going forward IRR2018) RPA2000 N Radiation Protection Supervisor* RPA Local rules, radiation safety culture, monitoring (IRR 99 and going forward IRR2018) Local training. Formal appointment Contactable Medical Physics Expert* (MPE) Optimization, dosimetry IRMER2000 and going forward IRMER2018 Eligible for or on (BSSD- IRMER2018) MPE Register Likely to be administered by RPS2000 Contactable for all. Present for research, complex

2017 British Nuclear Medicine Society

104. Guidelines for the prevention and control of carbapenem-resistant Enterobacteriaceae, Acinetobacter baumannii and Pseudomonas aeruginosa in health care facilities

, Singapore), Anna-Pelagia Magiorakos (European Centre for Disease Prevention and Control, Sweden), Shaheen Mehtar (Infection Control Africa Network and Stellenbosch University Faculty of Health Sciences, South Africa), Maria Luisa Moro (Agenzia Sanitaria e Sociale Regionale, Regione Emilia-Romagna, Italy), Babacar Ndoye (Infection Control Africa Network, Senegal), Folasade Ogunsola (College of Medicine, University of Lagos, Nigeria), Fernando Ota›za (Ministry of Health, Chile), Pierre Parneix (Centre de (...) Coordination de Lutte contre les Infections Nosocomiales Sud-Ouest [South-West France Health Care-Associated Infection Control Centre] and the Société Française d’Hygiène, Hôpital Pellegrin, France), Mitchell J. Schwaber (National Center for Infection Control of the Israel Ministry of Health; Sackler Faculty of Medicine, Tel Aviv University, Israel), Sharmila Sengupta (Medanta - The Medicity Hospital, India), Wing-Hong Seto (WHO Collaborating Centre for Infectious Disease Epidemiology and Control, Hong

2017 World Health Organisation Guidelines

105. Evidence-based Clinical Practice Guideline for Deprescribing Cholinesterase Inhibitors and Memantine

and supporting documents are available at: http://sydney.edu.au/medicine/cdpc/resources/deprescribing-guidelines.php Disclaimer This document is a general guide to be followed subject to the clinician’s judgement and the person’s preference in each individual case. The guideline is designed to provide information to assist decision making and is based on the best evidence available at the time of developing this publication. Publication approval The guideline recommendations on pages 7-9 of this document (...) , Ottawa, Canada Organisations endorsing this guideline ? Australian and New Zealand Society of Geriatric Medicine (ANZSGM) ? The Royal Australian and New Zealand College of Psychiatrists (RANZCP) ? Tasmanian Health Service: Royal Hobart Hospital ? Canadian Geriatrics Society (CGS) ? Canadian Society of Hospital Pharmacists (CSHP) Evidence-based clinical practice guideline for deprescribing cholinesterase inhibitors and memantine: 2018 4 Plain English Summary Dementia describes a syndrome

2018 Clinical Practice Guidelines Portal

107. Practical Management of Hyperglycaemic Hyperosmolar State (HHS) in children

started, underlying or precipitating causes of HHS (such as infection) must be identified and treated at the same time. Precipitating causes of HHS include infection, undiagnosed diabetes and substance abuse. A full clinical assessment should be carried out, including possible risk factors: ? history from family/patient ? physical examination looking for acanthosis nigricans, obesity, signs of trauma or infection ? mental state ? neurological state ? renal function assessment ? family history etc (...) of Children’s Diabetes Clinicians Clinicians Arieff AI, Carroll HJ. Nonketotic hyperosmolar coma with hyperglycemia: clinical features, pathophysiology, renal function, acid-base balance, plasma-cerebrospinal fluid equilibria and the effects of therapy in 37 cases. Medicine 1972;51:73-94. Corwell B, Knight B, Olivieri L, Willis GC. Current diagnosis and treatment of hyperglycemic emergencies. Emergency medicine clinics of North America 2014;32:437-52. Ng SM, Edge JA. Hyperglycaemic Hyperosmolar State (HHS

2018 British Society for Paediatric Endocrinology and Diabetes

108. Heavy menstrual bleeding: assessment and management

is it for? 4 Recommendations 5 1.1 Impact of heavy menstrual bleeding (HMB) on women 5 1.2 History, physical examination and laboratory tests 5 1.3 Investigations for the cause of HMB 6 1.4 Information for women about HMB and treatments 9 1.5 Management of HMB 10 Recommendations for research 17 1 Hysteroscopy compared with ultrasound or empiric pharmacological treatment in the diagnosis and management of heavy menstrual bleeding (HMB) 17 2 Effectiveness of the progestogen-only pill, injectable progestogens (...) Recommendations People have the right to be involved in discussions and make informed decisions about their care, as described in your care. Making decisions using NICE guidelines explains how we use words to show the strength (or certainty) of our recommendations, and has information about prescribing medicines (including off-label use), professional guidelines, standards and laws (including on consent and mental capacity), and safeguarding. 1.1 Impact of heavy menstrual bleeding (HMB) on women 1.1.1

2018 National Institute for Health and Clinical Excellence - Clinical Guidelines

109. Attention deficit hyperactivity disorder: diagnosis and management

://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 21 of 62current educational or employment circumstances risk assessment for substance misuse and drug diversion care needs a review of physical health, including: a medical history, taking into account conditions that may be contraindications for specific medicines current medication height and weight (measured and recorded against the normal range for age, height and sex) baseline pulse and blood pressure (measured with an appropriately sized cuff (...) have the right to be involved in discussions and make informed decisions about their care, as described in your care. Making decisions using NICE guidelines explains how we use words to show the strength (or certainty) of our recommendations, and has information about prescribing medicines (including off-label use), professional guidelines, standards and laws (including on consent and mental capacity), and safeguarding. 1.1 Service organisation and training Service organisation Service organisation

2018 National Institute for Health and Clinical Excellence - Clinical Guidelines

110. Management of opioid use disorders: a national clinical practice guideline

that many individuals may benefit from the ability to move between treatments. CPD VULNERABLE POPULATIONSGUIDELINE E248 CMAJ | MARCH 5, 2018 | VOLUME 190 | ISSUE 9 at the provincial, territorial and national levels for the development of evidence-based strategies. This guideline is intended to serve as a tool to address current gaps in care for opioid use disorder, addiction-medicine training for clinicians and other health care professionals, and treatment access policies across the country (...) , relevant individual experts and stakeholder organizations from their region, each clinical lead invited 7–13 individuals to partici- pate on the review committee. Including the clinical leads and principal investigators, the pan-Canadian review committee con- sisted of 43 individuals, including primary care physicians, addic- tion medicine physicians and other specialists, nurse practitio- ners and registered nurses, social workers, pharmacists, program managers and administrators, and policy-makers

2018 CPG Infobase

111. Management of Anaemia and Iron Deficiency in Patients With Cancer: ESMO Clinical Practice Guidelines

of Hematology and Oncology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, USA; 8 Medical Society for Blood Management, Laxenburg, Austria; 9 Klinik fu ¨r Innere Medizin I, Westpfalz-Klinikum, Kaiserslautern, Germany; 10 Department of Haematology, John Radcliffe Hospital, Oxford, UK; 11 Wilhelminen Cancer Research Institute, Wilhelminenspital, Vienna, Austria; 12 Karolinska Institute and Karolinska Hospital, Stockholm, Sweden; 13 Medica Oncology, IRCCS Asiana Pedaliter (...) Universitaria San Martino – IST, Institutor Nazionale per la Ricercars sol Chancre, Genova; 14 Department of Experimental and Clinical Medicine, Haematology, University of Florence, Florence, Italy; 15 Department of Medical Oncology, Ziekenhuisnetwerk Antwerpen, Antwerp, Belgium; 16 Department of Internal Medicine V (Haematology and Oncology), Innsbruck Medical University, Innsbruck, Austria; 17 Department of Medicine V, University of Heidelberg, Heidelberg, Germany; 18 Department of Oncology, Zealand

2018 European Society for Medical Oncology

112. Collaborative Framework for Care and Control of Tuberculosis and Diabetes

that the prevalence of diabetes will reach 438 million by 2030 and that 80% of prevalent cases will occur in the developing world (7). The increase is mainly driven by changes in diet and levels of physical activity (8). In the poorest countries, diabetes is more common among the better-off, but economic development quickly reverses this trend so that people from lower socioeconomic groups are more affected by diabetes; sequelae are worse among the poor in all countries (9). People from lower socioeconomic groups (...) with the activity of certain anti-TB medicines (18). Gaps in care and control of TB Over the past two decades, national TB control programmes worldwide have implemented TB control through DOTS and the Stop TB Strategy with evident success, including substantial increases in rates of case detection and improved treatment outcomes (1). However, improvements are still needed to tackle the following challenges: First, countries must ensure complete and early case detection of all types of TB. During 2005–2009

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2011 International Union Against TB and Lung Disease

113. Guidelines for the Clinical and Operational Management of Drug-Resistant Tuberculosis

and publisher. ISBN: 979-10-91287-03-6Contents Abbreviations ix 1 Justi? cation for the Guidelines 1 Justi? cation for the Guidelines: drug-resistant tuberculosis can be cured 1 The challenge of a new epidemic and the lack of anti-tuberculosis medicines 2 Lack of evidence in drug-resistant tuberculosis clinical and operational management 4 Objectives of the Guidelines 4 References 5 2 Historical background and global epidemiology of Mycobacterium tuberculosis resistance 7 Historical background of anti (...) ? 213 How are data tabulated, assessed and used to facilitate and improve management of multidrug-resistant tuberculosis in the future? 215 References 225 17 Management of second-line medicines for tuberculosis treatment 227 Introduction 227 Selection of medicines to treat drug-resistant tuberculosis patients 227 Quanti? cation 228 Procurement of drug-resistant tuberculosis medicines 229 Quality assurance of drug-resistant tuberculosis medicines purchased 229 Prices of drug-resistant tuberculosis

2013 International Union Against TB and Lung Disease

114. ABCD position statement on the risk of diabetic ketoacidosis with the use of sodium-glucose cotransporter-2 inhibitors

in urinary glucose loss and, therefore, fat dependent metabolism may persist for several days. Preventing DKA in high risk patients taking SGL T-2 inhibitors 1. Avoid or stop SGLT-2 inhibitors in situations likely to shift metabolism to a catabolic state rather than anabolic state i.e. at least 24 hours prior to a major elective surgery, planned invasive procedures or an anticipated severe stressful physical or mental activity such as running a marathon. The effect on glycosuria may persist for a few (...) article 20 of regulation (EC) 726/2004. London, UK: European Medicines Agency; 2015. Available at: http://www.ema.europa.eu/docs/en_GB/document_ library/Referrals document/SGLT2_inhibitors__20/ Procedure started/WC500187925.pdf (accessed June, 2016). 17. Tang H, Li D, Wang T, et al. Effect of Sodium–Glucose Cotransporter 2 Inhibitors on Diabetic Ketoacidosis Among Patients With Type 2 Diabetes: A Meta-analysis of Randomized Controlled Trials. Diabetes Care. 2016 Jun 14:dc160885. 18. West K, Webb LA

2016 Association of British Clinical Diabetologists

115. The Looming Co-epidemic of TB-Diabetes: A Call to Action

diseases—illnesses that are contagious and caused by germs. In the past few centuries, industrialization and economic development, lifestyle changes and the advent of modern medicine have induced a fundamental shift toward non-communicable diseases—primarily heart disease, cancer, diabetes, and chronic lung diseases. These changes were seen first in advanced market economies like the United States and Europe, but they are now sweeping through rapidly developing countries like India, China, Nigeria (...) . There are growing concerns that oral diabetes medicines can decrease the effectiveness of TB medicines. While controlling glucose levels likely reduces the risk of developing TB among people with diabetes, not enough research has been done to know if it’s enough to reduce the risks of developing TB or dying from it. It’s also not yet clear how to optimize glucose control in people who have both TB and diabetes. xxxi Diabetes increases the general risk of infection, but we do not actually know the precise

2014 International Union Against TB and Lung Disease

116. Implementing Collaborative TB-HIV Activities: A Programmatic Guide

to translation of ? ndings into strengthened policy and practice 71 Appendices 73 1 Post-exposure HIV prophylaxis 74 2 Practical steps for health-facility level antiretroviral treatment outcome analysis 76 3 Main tasks and responsibilities of TB-HIV coordinating bodies 79 4 Bottlenecks and potential solutions: lessons learnt from the Union-supported sites 80 5 Components of a good supply management system for medicines 81 6 Training needs for implementing collaborative TB-HIV activities 82 7 From de? ning (...) Centers for Disease Control and Prevention CNHPP Centre National Hospitalier de Pneumo Physiologie (National Referral Centre for Respiratory Medicine) CPT cotrimoxazole preventive therapy CXR chest X-ray DOT directly observed therapy DOTS Directly Observed Therapy, Short-Course DRC Democratic Republic of Congo DST drug susceptibility testing EC European Commission EFV efavirenz EQA external quality assurance FDC ? xed-dose combination GFATM Global Fund to Fight AIDS, Tuberculosis and Malaria HEPA high

2012 International Union Against TB and Lung Disease

117. Management of Tuberculosis: A Guide to the Essentials of Good Clinical Practice

of conferences following the ? rst international conference of specialists of internal medicine in 1867. It was ? rst of? cially registered in 1902 as the Central International Bureau for the Prevention of Consumption, and started its monthly pub- lication Tuberculosis in German, French and English. It has gained im- mense experience in collaborating with partners in providing care for mil- lions of tuberculosis patients in some of the poorest countries in the world, through the vehicle of National (...) patient.TUBERCULOSIS 11 Tuberculosis will be detected most ef? ciently where health care pro- viders and community members are highly aware of the symptoms sug- gestive of tuberculosis. 2.2.3. How is a diagnosis of tuberculosis con? rmed? A diagnosis is proposed by the health care worker after considering the history given by the patient (the symptoms) and the evidence resulting from physical examination of the patient (the signs). The process of diag- nosis involves identifying the most likely condition

2010 International Union Against TB and Lung Disease

119. Routine psychosocial care in infertility and medically assisted reproduction ? A guide for fertility staff

Needs, 2008). Why was this guideline produced? The World Health Organization defines health as a ‘state of complete physical, mental and social well- being and not merely the absence of disease or infirmity’ (World Health Organization, 2007). This definition highlights the many dimensions (anatomical, physiological, and mental) of health and the importance of providing adequate care to address them all and not only to treat the disease. In infertility care, this is especially important for several (...) are: postponement of treatment (i.e., stopping treatment for at least 1 year), logistics and practical reasons, rejection of treatment, perception of poor prognosis, and the psychological burden of treatment.(A) • the reasons patients state for discontinuing recommended treatment after one failed IVF/ICSI cycle are: financial issues, the psychological and physical burdens of treatment, clinic-related reasons and organizational problems, postponement of treatment (or unknown), and relational problems

2015 European Society of Human Reproduction and Embryology

120. Care in the Last Days of Life

that hospital admission or transfer to a high-dependency unit or intensive treatment unit is not appropriate. While this guideline focuses on physical symptoms, psychosocial and spiritual issues will also need to be addressed to give holistic care. Assessment Identify any potentially reversible causes for the patient’s deterioration. These may include: dehydration infection opioid toxicity steroid withdrawal acute kidney injury hypo or hyperglycaemia Start treatment, if appropriate for the individual (...) , planned review and documentation of the care plan will make sure the best care is given as the patient’s condition deteriorates, stabilises or improves. Food and drinks : support the patient to take these as long as they are able and want to. Comfort care : usually includes an alternating pressure mattress to minimise avoidable skin breakdown due to overall deterioration of condition, repositioning for comfort, eye care, mouth care, bladder and bowel care. Medicines : review and stop any treatments

2015 Scottish Palliative Care Guidelines

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