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1. Using Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients

Using Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients LABORATORY MEDICINE PRACTICE GUIDELINES EDITED BY LORALIE J. LANGMAN AND PAUL J. JANNETTO Using Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients Co-Sponsored byLABORATORY MEDICINE PRACTICE GUIDELINES Using Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients Loralie J. Langman Committee Chair Department of Laboratory Medicine and Pathology Mayo Clinic (...) References 101 Table of ContentsLABORATORY MEDICINE PRACTICE GUIDELINES Using Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients 5 Executive Summary Introduction The American Association for Clinical Chemistry (AACC) Acad- emy, formerly the National Academy of Clinical Biochemistry (NACB), has developed a laboratory medicine practice guidelines (LMPG) for using laboratory tests to monitor drug therapy in pain management patients. The scope and purpose of this guideline

2018 American Academy of Pain Medicine

2. The care of the patient with amyotrophic lateral sclerosis: drug, nutritional, and respiratory therapies

The care of the patient with amyotrophic lateral sclerosis: drug, nutritional, and respiratory therapies Practice Parameter update: The care of the patient with amyotrophic lateral sclerosis: Drug, nutritional, and respiratory therapies (an evidence-based review) | Neurology Advertisement Search for this keyword Main menu User menu Search Search for this keyword The most widely read and highly cited peer-reviewed neurology journal Share October 13, 2009 ; 73 (15) Special Article Practice (...) Parameter update: The care of the patient with amyotrophic lateral sclerosis: Drug, nutritional, and respiratory therapies (an evidence-based review) Report of the Quality Standards Subcommittee of the American Academy of Neurology R. G. Miller , C. E. Jackson , E. J. Kasarskis , J. D. England , D. Forshew , W. Johnston , S. Kalra , J. S. Katz , H. Mitsumoto , J. Rosenfeld , C. Shoesmith , M. J. Strong , S. C. Woolley First published October 12, 2009, DOI: https://doi.org/10.1212/WNL.0b013e3181bc0141 R

2009 American Academy of Neurology

3. Administration of medicinal products by non - medical personnel as part of Clinical Nuclear Medicine Procedures

and assessment’ 4 More detailed information on each licensed drug is available in the manufacturers Summary of Product Characteristics (SPC) and the British National Formulary (BNF) This guidance is not intended to cover medicines used for clinical treatment of adverse events occurring during nuclear medicine procedures (eg. Reaction to any pharmaceutical administered including the relevant radiopharmaceutical, worsening of a pre-existing condition such as asthma) or non-pharmaceutical adjuncts used (...) adverse reaction • Communication with patients; o eliciting relevant information on potential contraindications, allergies and concurrent drug therapy o obtaining consent to administer the medicine o advice to patient about potential delayed affects and actions required • Intravenous injection and infusion • Intermediate Life Support • Relevant documentation MEDICINES USED IN NUCLEAR MEDICINE AS PART OF THE CLINICAL PROCEDURE (2013) [ * Medicines for which this draft contains sample templates] Page 6

2013 British Nuclear Medicine Society

4. Administration of medicinal products by non - medical personnel as part of Clinical Nuclear Medicine Procedures

information on each drug is available in the manufacturers Summary of Product Characteristics (SPC) and the British National Formulary (BNF) This guidance is not intended to cover medicines used for clinical treatment of adverse events occurring during nuclear medicine procedures (eg. Reaction to any pharmaceutical administered including the relevant radiopharmaceutical, worsening of a pre-existing condition such as asthma) or non-pharmaceutical adjuncts used in nuclear medicine (eg. Lemon juice, fatty (...) (normally single dose or short-term administration). ? Recognition of, and appropriate action to take, in the case of suspected adverse reaction ? Communication with patients; o eliciting relevant information on potential contraindications, allergies and concurrent drug therapy o obtaining consent to administer the medicine o advice to patient about potential delayed affects and actions required ? Intravenous injection and infusion ? Intermediate Life Support ? Relevant documentationPage 6 of 44 Version

2010 British Nuclear Medicine Society

5. Improving Adherence to Therapy and Clinical Outcomes While Containing Costs: Opportunities From the Greater Use of Generic Medications: Best Practice Advice From the Clinical Guidelines Committee of the American College of Physicians Full Text available with Trip Pro

. Diabetes Care 2009 32 647 9 Briesacher BA , Andrade SE , Fouayzi H , Chan KA . Medication adherence and use of generic drug therapies. Am J Manag Care 2009 15 450 6 Shrank WH , Hoang T , Ettner SL , Glassman PA , Nair K , DeLapp D . et al The implications of choice: prescribing generic or preferred pharmaceuticals improves medication adherence for chronic conditions. Arch Intern Med 2006 166 332 7 Taira DA , Wong KS , Frech-Tamas F , Chung RS . Copayment level and compliance with antihypertensive (...) Improving Adherence to Therapy and Clinical Outcomes While Containing Costs: Opportunities From the Greater Use of Generic Medications: Best Practice Advice From the Clinical Guidelines Committee of the American College of Physicians Opportunities From the Greater Use of Generic Medications | Annals of Internal Medicine | American College of Physicians '); } '); })(); Sign in below to access your subscription for full content INDIVIDUAL SIGN IN | You will be directed to acponline.org

2015 American College of Physicians

6. Medical Training to Achieve Competency in Lifestyle Counseling: An Essential Foundation for Prevention and Treatment of Cardiovascular Diseases and Other Chronic Medical Conditions: A Scientific Statement From the American Heart Association Full Text available with Trip Pro

examples of leading medical schools that have integrated behavioral, nutrition, or physical activity sciences and counseling skills as part of their curricula. We mention postgraduate opportunities for lifestyle medicine training and provide links to detailed information about both MD and postgraduate programs. We also provide an overview of institutional and student program evaluations regarding lifestyle concepts and skills training included in US medical school curricula. Behavioral Sciences (...) and treat NCDs, as well as how to improve their communication skills with patients regarding lifestyle medicine counseling. Postgraduate Programs and Continuous Medical Education In addition to the critical role of medical schools in teaching the fundamentals of behavioral sciences, tobacco use, nutrition, and physical activity to future physicians, opportunities for postgraduate training during residencies and fellowships are essential, as is continuing medical education. We believe that all primary

2016 American Heart Association

7. Medical Emergencies - medical emergencies in adults (overview)

haemorrhage ? where appropriate, consider cannulation for drug administration. Fluid Therapy NOTE: Special guidance applies in pregnant women (refer to speci?c guidelines in the obstetrics and gynaecological section). Current research shows little evidence to support the routine use of IV ?uids in adult acute blood loss. In circumstances such as penetrating chest and abdominal trauma, survival worsens with the routine use of IV ?uids. 2 Fluids may raise the blood pressure, cool the blood and dilute (...) ? social history. Combined with a good physical examination, this format of history taking should ensure that you correctly identify those patients who are time critical, urgent or routine. The history taken must be fully documented. In many cases, a well-taken history will point to the diagnosis. The presence of “Medic Alert” type jewellery (bracelets or necklets) can provide information on the patient’s pre-existing health risk that may be relevant to the current medical emergency. SECONDARY SURVEY

2007 Joint Royal Colleges Ambulance Liaison Committee

8. Physical health and drug safety in individuals with schizophrenia Full Text available with Trip Pro

Physical health and drug safety in individuals with schizophrenia While antipsychotic medications are the mainstay of therapy for individuals with schizophrenia and psychotic disorders, their use is associated with adverse effects on physical health that require the attention and care of prescribers.We used the ADAPTE process to adapt existing guideline recommendations from the National Institute for Health and Care Excellence (NICE) and Scottish Intercollegiate Guidelines Network (SIGN (...) interventions are recommended to mitigate antipsychotic-induced weight gain. Prescribers should follow Canadian guidelines on the treatment of obesity, dyslipidemia, and diabetes. Recommendations on antipsychotic drug choice are made for users particularly concerned about extrapyramidal symptoms.Careful monitoring and attention by prescribers may mitigate adverse effects associated with antipsychotic medications.

2017 CPG Infobase

9. Appropriate prescribing of psychotropic medication for non-cognitive symptoms in people with dementia

Grading of Recommendations Assessment, Development and Evaluation GDG Guideline Development Group GDP Global Domestic Product MCI Mild Cognitive Impairment MHBC Ministry of Health British Columbia MHRA Medicines and Healthcare products Regulatory Agency NCEC National Clinical Effectiveness Committee NHMRC National Health and Medical Research Council NHS National Health Service NICE National Institute for Health and Care Excellence NPI Neuropsychiatric Inventory PBS Pharmaceutical Benefit Scheme PDD (...) . However, most evidence is based on common dementia types, particularly Alzheimer’s dementia; this needs to be borne in mind by the user when applying the evidence to other dementia types. Clinicians’ attention is also drawn to the fact that many psychotropic medications are used “off label” for people with dementia, particularly antipsychotic medication. While this is not prohibited by medicine regulations, it does require particular caution by the prescriber. This National Clinical Guideline

2019 National Clinical Guidelines (Ireland)

10. Guideline for Classification of the Acute Emetogenic Potential of Antineoplastic Medication in Pediatric Cancer Patients

and other health care providers who care for children aged 1 month to 18 years who are receiving antineoplastic medication with an approach to assess the emetogenic potential of antineoplastic regimens. Assessment of the emetogenic potential of antineoplastic therapy is the first step in the decision of whether or not, and to what extent, to provide antiemetic prophylaxis. The scope of this guideline is limited to the assessment of antineoplastic therapy emetogenicity in the acute phase (within 24 hours (...) of administration of an antineoplastic agent). Its scope does not include anticipatory, breakthrough or delayed phase AINV, or nausea and vomiting that is related to radiation therapy, disease, co- incident conditions or end-of-life care. In addition, this guideline is most applicable to children who are naïve to antineoplastic therapy and who are about to receive their first course of antineoplastic therapy. In the case of children who have received antineoplastic medication in the past, estimation

2010 SickKids Supportive Care Guidelines

11. Prevention of Acute Nausea and Vomiting due to Antineoplastic Medication in Pediatric Cancer Patients

: Additional Literature Search: Dronabinol and Levomepromazine 142 Appendix E: Quality of Evidence and Strength of Recommendation 148 Appendix F: Tables of Included Studies 149 F.1 Summary of studies used to inform recommendation #2a 149 F.1a Highly emetogenic antineoplastic therapy as ranked by POGO Guideline for Classification of the Acute Emetogenic Potential of antineoplastic Medication in Pediatric Cancer Patients 5 Version date: February 28, 2013 F.1b Highly emetogenic antineoplastic therapy (...) as ranked by study investigators where insufficient information available to assign emetogenic risk using the POGO Guideline for Classification of the Acute Emetogenic Potential of antineoplastic Medication in Pediatric Cancer Patients F.2 Summary of studies used to inform recommendation #2b 154 F.2a Moderately emetogenic antineoplastic therapy as ranked by POGO Guideline for Classification of the Acute Emetogenic Potential of antineoplastic Medication in Pediatric Cancer Patients F.2b Moderately

2013 SickKids Supportive Care Guidelines

12. Policy on Medically-Necessary Care

and pro-vision of individual and community-based health care programs to achieve comprehensive health care. 2. Establishment of a dental home for all children by 12 months of age in order to institute an individualized preventive oral health program based upon each patient’s unique caries risk assessment. 3. Healthcare providers who diagnose oral disease to either provide therapy or refer the patient to a primary care dentist or dental/medical specialist as dictated by the nature and complexity (...) 2000;22(1):27-32. 67. Prabhu NT, Nunn JH, Evans DJ. A comparison of costs in providing dental care for special needs patients under sedation or general anesthesia in the North East of England. Prim Dent Care 2006;13(4):125-8. 68. Institute of Medicine Committee on Medicare Coverage Extensions. Medically necessary dental services. In; Field MJ, Lawrence RL, Zwanziger L, eds. Extending Medicare Coverage for Preventive and Other Services. Washington (DC): National Academies Press (US); 2000. Available

2019 American Academy of Pediatric Dentistry

13. Australian Institute of Sport and Australian Medical Association position statement on concussion in sport

is suspected, the athlete must be immediately removed from sport and not be allowed to return to activity until they have been assessed by a medical practitioner. “If in doubt, sit them out.” A diagnosis of concussion requires immediate physical and cognitive rest, followed by a structured, graduated return to physical activity. Children require a longer period of recovery from concussion. Algorithms are provided for use by medical and non-medically trained stakeholders in the recognition and management (...) Australian Institute of Sport and Australian Medical Association position statement on concussion in sport Australian Institute of Sport and Australian Medical Association position statement on concussion in sport | The Medical Journal of Australia mja-search search Use the for more specific terms. Title contains Body contains Date range from Date range to Article type Author's surname Volume First page doi: 10.5694/mja__.______ Search Reset  close Individual Login Purchase options Connect

2017 MJA Clinical Guidelines

14. Medical Abortion

, clinical trials, and observational studies published from June 1986 to November 2015 in English. Additionally, existing guidelines from other countries were consulted for review. A grey literature search was not required. Values The quality of evidence in this document was rated using the criteria described in the Report of the Canadian Task Force for Preventive Medicine rating scale ( Table 1 ). Benefits, Harms and/or Costs Medical abortion is safe and effective. Complications from medical abortion (...) , gestational age can be estimated using last menstrual period (LMP), clinical history, and physical examination, in women who are certain of the date of their LMP. Ultrasound is needed when uncertainty remains. (Level II-2) 4. The probability of ectopic pregnancy among women requesting abortion is consistently lower than in the general population. (Level II-3) Medical abortion regimens 5. There is limited evidence regarding teratogenicity of mifepristone, but overall the risk appears to be low. (Level III

2016 Society of Obstetricians and Gynaecologists of Canada

15. Intrapartum care for women with existing medical conditions or obstetric complications and their babies

medical conditions or obstetric complications and their babies (NG121) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Last updated April 2019 Page 24 of 961.6.11 Be aware that non-steroidal anti-inflammatory drugs can add to the risk of bleeding. 1.6.12 Before discharge from hospital, inform women with bleeding disorders of the risk of secondary bleeding postpartum and how to access care. T o find out why the committee (...) Intrapartum care for women with existing medical conditions or obstetric complications and their babies Intr Intrapartum care for women with apartum care for women with e existing medical conditions or obstetric xisting medical conditions or obstetric complications and their babies complications and their babies NICE guideline Published: 6 March 2019 www.nice.org.uk/guidance/ng121 © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice

2019 National Institute for Health and Clinical Excellence - Clinical Guidelines

16. Medical management of abortion

of abortion (medical abortion): Use of pharmacological drugs to terminate pregnancy. Sometimes the terms “non-surgical abortion” or “medication abortion” are also used. Routes of misoprostol administration: oral pills are swallowed; buccal pills are placed between the cheek and gums and swallowed after 30 minutes; sublingual pills are placed under the tongue and swallowed after 30 minutes; vaginal pills are placed in the vaginal fornices (deepest portions of the vagina) and the individual is instructed (...) , auxiliary nurse midwives, nurses, midwives, associate/advanced associate clinicians, and non-specialist and specialist doctors. Doctors of complementary systems of medicine can be providers of this service in health system contexts with an established mechanism for the participation of such doctors in other tasks related to maternal and reproductive health (10). Alongside non-specialist and specialist doctors, the following cadres can provide medical abortion for pregnancies = 12 weeks in contexts where

2019 World Health Organisation Guidelines

17. A guide to understanding the implications of the Ionising Radiation (Medical Exposure) Regulations in diagnostic and interventional radiology

and definitions 7 The employer 7 The employer’s responsibilities 7 The employer’s responsibilities for training 8 The referrer 9 Information required for a referral 9 Electronic requesting 10 The practitioner 10 Detriments to be considered in justifying an exposure 12 The operator 12 Professional responsibility 13 Authorisation 13 The role of the medical physics expert 13 The role of individuals who are not registered healthcare professionals such as radiography assistant practitioners in practical aspects (...) Royal College of Radiologists (RCR), Society and College of Radiographers (SCoR) and Institute of Physics and Engineering in Medicine (IPEM) document was published offering guidance on IR(ME)R for the radiotherapy community. 2 This was well received and became a respected guidance document. It is now apparent that practical guidance on the implications of IR(ME)R would benefit the radiology and interventional imaging community. The RCR, the SCoR, and the BIR (British Institute of Radiology) have

2015 Royal College of Radiologists

18. Medical eligibility criteria for contraceptive use

for meta-analyses was provided by Rochelle Fu. Technical and copy-editing were provided by Jura Editorial Services (jura-eds.com) and Green Ink, United Kingdom (greenink.co.uk). Funding The development of this guideline was financially supported by the National Institutes of Health (NIH) and United States Agency for International Development (USAID).Medical eligibility criteria for contraceptive use - Executive summary | 3 Abbreviations ART antiretroviral therapy ARV antiretroviral (medication) ß-hCG (...) device CVR combined contraceptive vaginal ring CYP3A4 cytochrome P450 3A4 enzyme DMPA depot medroxyprogesterone acetate DMPA-IM depot medroxyprogesterone acetate – intramuscular DMPA-SC depot medroxyprogesterone acetate – subcutaneous DVT deep vein thrombosis ECP emergency contraceptive pill EE ethinyl estradiol E-IUD emergency intrauterine device EMA European Medicines Agency ETG etonogestrel FAB fertility awareness-based methods FDA United States Food and Drug Administration GDG Guideline

2015 World Health Organisation Guidelines

19. Chronic pain disorder medical treatment guideline.

of habit-forming potential, withdrawal symptoms, and sedating side effects. Flurazepam has an active metabolite with a very long half-life, resulting in drug accumulation and next-day somnolence. These medications are not recommended for use in the working populations. Evidence Statements Regarding Hypnotics and Sedatives Some Evidence Zolpidem does not appreciably enhance the effectiveness of cognitive behavioral therapy (Design: Randomized clinical trial ). Nonsteroidal Anti-Inflammatory Drugs (...) of individual and/or group patient education as a means of facilitating self-management of symptoms Psychological or psychosocial screening should be performed on all chronic pain patients. Acupuncture Acupuncture is recommended for subacute or chronic pain patients who are trying to increase function and/or decrease medication usage and have an expressed interest in this modality. It is also recommended for subacute or acute pain for patients who cannot tolerate nonsteroidal anti-inflammatory drugs (NSAIDs

2017 National Guideline Clearinghouse (partial archive)

20. Complex regional pain syndrome/reflex sympathetic dystrophy medical treatment guideline.

medications, and it should generally be used in conjunction with manipulative and physical therapy/rehabilitation. Refer to the Division's for indications, evidence, and time frames. Biofeedback Biofeedback is a form of behavioral medicine that helps patients learn self-awareness and self-regulation skills for the purpose of gaining greater control of their physiology, such as muscle activity, brain waves, and measures of autonomic nervous system activity. Stress-related psycho-physiological reactions may (...) modalities, a number of which are generally accepted and supported by some scientific literature and others which still remain outside the generally accepted practice of conventional Western medicine. In many of these approaches, there is attention given to the relationship between physical, emotional, and spiritual well-being. While CAM may be performed by a myriad of both licensed and non-licensed health practitioners with training in one or more forms of therapy, credentialed practitioners should

2017 National Guideline Clearinghouse (partial archive)

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