How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

8,903 results for

tetracycline

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

21. The Presence of Cu Facilitates Adsorption of Tetracycline (TC) onto Water Hyacinth Roots Full Text available with Trip Pro

The Presence of Cu Facilitates Adsorption of Tetracycline (TC) onto Water Hyacinth Roots Batch experiments were conducted to investigate the adsorption characteristics of tetracycline (TC), and the interactive effects of copper (Cu) on the adsorption of TC onto water hyacinth roots. TC removal efficiency by water hyacinth roots was ranging from 58.9% to 84.6%, for virgin TC, 1:1 TC-Cu and 1:2 TC-Cu. The Freundlich isotherm model and the pseudo-second-order kinetic model fitted the adsorption

2018 International journal of environmental research and public health

22. Rapid detection of tetracycline resistance in bovine Pasteurella multocida isolates by MALDI Biotyper antibiotic susceptibility test rapid assay (MBT-ASTRA) Full Text available with Trip Pro

Rapid detection of tetracycline resistance in bovine Pasteurella multocida isolates by MALDI Biotyper antibiotic susceptibility test rapid assay (MBT-ASTRA) Pasteurella multocida is notorious for its role as an opportunistic pathogen in infectious bronchopneumonia, the economically most important disease facing cattle industry and leading indication for antimicrobial therapy. To rationalize antimicrobial use, avoiding imprudent use of highly and critically important antimicrobials for human (...) medicine, availability of a rapid antimicrobial susceptibility test is crucial. The objective of the present study was to design a MALDI Biotyper antibiotic susceptibility test rapid assay (MBT-ASTRA) procedure for tetracycline resistance detection in P. multocida. This procedure was validated on 100 clinical isolates with MIC-gradient strip test, and a comparison with disk diffusion was made. Sensitivity and specificity of the MBT-ASTRA procedure were 95.7% (95% confidence interval (CI) = 89.8-101.5

2018 Scientific reports

23. Mitochondria as oncotarget: a comparison between the tetracycline analogs doxycycline and COL-3 Full Text available with Trip Pro

Mitochondria as oncotarget: a comparison between the tetracycline analogs doxycycline and COL-3 Tetracyclines have anticancer properties in addition to their well-known antibacterial properties. It has been proposed that tetracyclines slow metastasis and angiogenesis through inhibition of matrix metalloproteinases. However, we believe that the anticancer effect of tetracyclines is due to their inhibition of mitochondrial protein synthesis, resulting in a decrease of the mitochondrial energy (...) generating capacity. Several groups have developed analogs that are void of antibacterial action. An example is COL-3, which is currently tested for its anticancer effects in clinical trials. We have undertaken a comparative study of the tetracycline analogs COL-3 and doxycycline, which has an antibacterial function, to further investigate the role of the mitochondrial energy generating capacity in the anticancer mechanism and, thereby, evaluate the usefulness of mitochondria as an oncotarget. Our

2018 Oncotarget

24. Effects of 462 nm Light-Emitting Diode on the Inactivation of Escherichia coli and a Multidrug-Resistant by Tetracycline Photoreaction Full Text available with Trip Pro

Effects of 462 nm Light-Emitting Diode on the Inactivation of Escherichia coli and a Multidrug-Resistant by Tetracycline Photoreaction The adaptability of bacterial resistance to antibiotics contributes to its high efficiency during evolution. Tetracycline (TC) is a broad-spectrum antimicrobial agent. Chromatographic analyses and mass spectrometry were used to study the effects of the light illumination of a 462 nm light-emitting diode (LED) on the conformational changes of TC in a phosphate

2018 Journal of clinical medicine

25. Synthesis and Phase Transformation Studies of Dysprosium-Doped Bi4V2O11 Nanoparticles and Their Application in Visible Light Photocatalytic Degradation of Tetracycline Drug Full Text available with Trip Pro

Synthesis and Phase Transformation Studies of Dysprosium-Doped Bi4V2O11 Nanoparticles and Their Application in Visible Light Photocatalytic Degradation of Tetracycline Drug Recently, Bi4V2O11 as an electrolyte material has pulled in considerable consideration because of its remarkable novel applications. In this article, novel, dysprosium-doped (x = 0.2, 0.3, 0.4, and 0.5) Bi4V2O11 (Dy/BVO) nanoparticles have been synthesized by sol-gel strategy. The photocatalyst Dy/BVO nanoparticles exhibit (...) higher photocatalytic efficiency than BVO nanoparticles assessed by debasement of tetracycline drug under visible light illumination. Our work focuses on the phase transformation, conducting properties, and mechanisms of the Dy/BVO nanoparticles in relation to execute some methods of processing and manufacturing product in commercial applications. The characterization of Dy/BVO was performed by Fourier transform infrared, X-ray diffraction, scanning electron microscopy, energy-dispersive X-ray

2018 ACS Omega

26. Simple Urea Immersion Enhanced Removal of Tetracycline from Water by Polystyrene Microspheres Full Text available with Trip Pro

Simple Urea Immersion Enhanced Removal of Tetracycline from Water by Polystyrene Microspheres Antibiotics pose potential ecological risks in the water environment, necessitating their effective removal by reliable technologies. Adsorption is a conventional process to remove such chemicals from water without byproducts. However, finding cheap adsorbents with satisfactory performance is still a challenge. In this study, polystyrene microspheres (PSM) were enhanced to adsorb tetracycline (...) by surface modification. Simple urea immersion was used to prepare urea-immersed PSM (UPSM), of which surface groups were characterized by instruments to confirm the effect of immersion. Tetracycline hydrochloride (TC) and doxycycline (DC) were used as typical adsorbates. The adsorptive isotherms were interpreted by Langmuir, Freundlich, and Tempkin models. After urea immersion, the maximum adsorption capacity of UPSM at 293 K and pH 6.8 increased about 30% and 60%, achieving 460 mg/g for TC and 430 mg/g

2018 International journal of environmental research and public health

27. A tetracycline-inducible CRISPR/Cas9 system, targeting two long non-coding RNAs, suppresses the malignant behavior of bladder cancer cells Full Text available with Trip Pro

A tetracycline-inducible CRISPR/Cas9 system, targeting two long non-coding RNAs, suppresses the malignant behavior of bladder cancer cells Clustered regularly interspaced short palindromic repeats (CRISPR) associated protein 9 (Cas9) technology has been applied in varied biological studies, including cancer studies. However, stable mRNA expression of Cas9 has potential risks in future gene therapy. Therefore, in the present study, a tetracycline-inducible switch was used to control the mRNA (...) expression of Cas9. Long non-coding RNAs (lncRNAs) may be important functional regulators in tumor development, including in bladder cancer. RNA was designed to simultaneously target two lncRNAs, PVT1 and ANRIL, which are considered to be bladder cancer oncogenes. The mRNA expression of Cas9 was controlled by doxycycline. Reverse transcription-quantitative polymerase chain reaction revealed that the expression of PVT1 and ANRIL was significantly inhibited by the tetracycline-inducible CRISPR/Cas9 system

2018 Oncology letters

28. Xylose Improves Antibiotic Activity of Chloramphenicol and Tetracycline against K. pneumoniae and A. baumannii in a Murine Model of Skin Infection Full Text available with Trip Pro

Xylose Improves Antibiotic Activity of Chloramphenicol and Tetracycline against K. pneumoniae and A. baumannii in a Murine Model of Skin Infection Increased resistance to antimicrobials in clinically important bacteria has been widely reported. The major mechanism causing multidrug resistance (MDR) is mediated by efflux pumps, proteins located in the cytoplasmic membrane to exclude antimicrobial drug. Some efflux pumps recognize and expel a variety of unrelated antimicrobial agents, while other (...) skin of mice. Mice treated with the antibiotic alone or with a mixture of glucose and antibiotics or xylose and antibiotics were compared to a control group that was infected but received no further treatment. We observed that the mixtures xylose-tetracycline and xylose-chloramphenicol produced a decrease of at least 10 times viable Acinetobacter baumannii and Klebsiella pneumoniae recovered from infected skin, compared with mice treated with the antibiotic alone. Our results show that xylose

2018 The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien des Maladies Infectieuses et de la Microbiologie Médicale

29. Assessment of Binding Interaction between Bovine Lactoferrin and Tetracycline Hydrochloride: Multi-Spectroscopic Analyses and Molecular Modeling Full Text available with Trip Pro

Assessment of Binding Interaction between Bovine Lactoferrin and Tetracycline Hydrochloride: Multi-Spectroscopic Analyses and Molecular Modeling In this paper, the interaction between bovine lactoferrin (bLf) and tetracycline hydrochloride (TCH) was researched by microscale thermophoresis (MST), multi-spectroscopic methods, and molecular docking techniques. Normal fluorescence results showed that TCH effectively quenched the intrinsic fluorescence of bLf via static quenching. Moreover, MST

2018 Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry

30. Occurrence and Distribution of Tetracycline Antibiotics and Resistance Genes in Longshore Sediments of the Three Gorges Reservoir, China Full Text available with Trip Pro

Occurrence and Distribution of Tetracycline Antibiotics and Resistance Genes in Longshore Sediments of the Three Gorges Reservoir, China The widespread use of antibiotics and the induced antibiotic resistance genes have attracted much attention in recent years. The longshore sediments in the water-level-fluctuating zone of the Three Gorges Reservoir were selected to investigate the spatial-temporal distribution of antibiotics and antibiotic resistance genes in two different operation stages (...) (low-water level in summer and high-water level in winter). Three kinds of tetracycline antibiotics (tetracycline, oxytetracycline, and chlortetracycline) and three kinds of tetracycline resistance genes [tet(A), tet(C), and tet(M)] were analyzed and quantified. The results showed that the distribution of tetracyclines and resistance genes in riverine, transition and lacustrine zones showed a certain regularity, and the tetracycline antibiotics concentration and the total abundance

2018 Frontiers in microbiology

31. Distribution Characteristics and Ecological Risk Assessment of Tetracyclines Pollution in the Weihe River, China Full Text available with Trip Pro

Distribution Characteristics and Ecological Risk Assessment of Tetracyclines Pollution in the Weihe River, China To examine the residual and distributions of tetracycline antibiotics in the Weihe River, SPE-UPLC (solid phase extraction-ultra performance liquid chromatography with UV-Vis detection) was employed to analyze the oxytetracycline (OTC), chlortetracycline (CTC), and minocycline (MC) of 41 surface water and 35 sediment samples collected from main streams, tributaries, and main sewage (...) outlets. The results showed that: (1) The order of residual levels of tetracycline antibiotics in water and sediment from high to low was the following: OTC > CTC > MC., considering the water solubilities are 313 mg/L, 630 mg/L, and 50200mg/L and octanol water partition coefficients (Kow) are 7.94, 4.16, and 1.12 for OTC, CTC, and MC, respectively. Thus, the distribution of antibiotics was not only related to the basic properties of antibiotics, but also some environmental factors. The concentrations

2018 International journal of environmental research and public health

32. Eggshell Membrane-Templated MnO2 Nanoparticles: Facile Synthesis and Tetracycline Hydrochloride Decontamination Full Text available with Trip Pro

Eggshell Membrane-Templated MnO2 Nanoparticles: Facile Synthesis and Tetracycline Hydrochloride Decontamination Taking advantages of reticular proteins and reductive groups on the surface, eggshell membrane (ESM) was selected to synthesize MnO2 nanoparticles from potassium permanganate through a super simple way in which ESM acted as both template and reductant. This process avoided harsh reaction conditions or complicated aftertreatments and thus owned the merits of green synthesis, handy (...) operation, low cost, and easy purification. The ESM-templated MnO2 nanoparticles (MnO2 NPs/ESM) were characterized, and the content of nanomaterials on the template was tested. MnO2 NPs/ESM showed a good capacity for decontamination of tetracycline hydrochloride (TCH). The macroscopical materials can be separated easily by taking the membrane out to stop the degradation instead of centrifugation or filtration. It was studied that 72.27% of TCH (50 mg/L) was decontaminated in 20 min by 0.1920 g/L MnO2

2018 Nanoscale research letters

33. Human Campylobacteriosis in Italy: Emergence of Multi-Drug Resistance to Ciprofloxacin, Tetracycline, and Erythromycin Full Text available with Trip Pro

Human Campylobacteriosis in Italy: Emergence of Multi-Drug Resistance to Ciprofloxacin, Tetracycline, and Erythromycin Campylobacter spp. is one of the main cause of bacterial gastroenteritis in the world. The increase of antibiotic resistance in this species is a threat to public health. A Campylobacter spp. surveillance study was performed in Italy in the 2013-2016 period by the Enter-Net Italia network. The most prevalent Campylobacter species identified causing gastroenteritis (...) was Campylobacter jejuni (73.4%) and 45% of all the annual cases of campylobacteriosis were reported in the summer period. High rates of ciprofloxacin and tetracycline resistance in Campylobacter spp. have been observed. An increasing percentage of Campylobacter coli strains simultaneously resistant to ciprofloxacin, tetracycline and erythromycin has been found. Molecular mechanisms of resistance have been investigated and the role of efflux pumps evaluated. Antibiotic resistance in Campylobacter spp

2018 Frontiers in microbiology

34. TiO2 Nanotubes/Ag/MoS2 Meshy Photoelectrode with Excellent Photoelectrocatalytic Degradation Activity for Tetracycline Hydrochloride Full Text available with Trip Pro

TiO2 Nanotubes/Ag/MoS2 Meshy Photoelectrode with Excellent Photoelectrocatalytic Degradation Activity for Tetracycline Hydrochloride A novel type of TiO₂ nanotubes (NTs)/Ag/MoS₂ meshy photoelectrode was fabricated with highly oriented TiO₂ nanotube arrays grown from a Ti mesh supporting Ag nanoparticles and three-dimensional MoS₂ nanosheets. In this structure, Ag nanoparticles act as bridges to connect MoS₂ and TiO₂ and pathways for electron transfer, ensuring the abundant production of active (...) electrons, which are the source of •O₂-. The TiO₂ NTs/Ag/MoS₂ mesh can be used as both photocatalyst and electrode, exhibiting enhanced photoelectrocatalytic efficiency in degrading tetracycline hydrochloride under visible light irradiation (λ ≥ 420 nm). Compared to unmodified TiO₂ NTs, the improved photoelectrocatalytic activity of the TiO₂ NTs/Ag/MoS₂ arise from the formation of Z-scheme heterojunctions, which facilitate the efficient separation of photogenerated electron-hole pairs through

2018 Nanomaterials

35. Improvement of dermal delivery of tetracycline using vesicular nanostructures Full Text available with Trip Pro

Improvement of dermal delivery of tetracycline using vesicular nanostructures The objective of this investigation was to study the potential use of nanoliposomes and nanotransfersomes in dermal delivery of tetracycline hydrochloride (TC) for acne treatment. Vesicular nanostructures were prepared by thin film hydration method and evaluated for their size, zeta potential, morphology, and entrapment efficiency. Minimal inhibitory concentration values of TC-loaded vesicles were evaluated

2018 Research in pharmaceutical sciences

36. Decreased Porphyromonas gingivalis adhesion and improved biocompatibility on tetracycline-loaded TiO2 nanotubes: an in vitro study Full Text available with Trip Pro

Decreased Porphyromonas gingivalis adhesion and improved biocompatibility on tetracycline-loaded TiO2 nanotubes: an in vitro study Titanium dioxide (TiO2) nanotubes are often used as carriers for loading materials such as drugs, proteins, and growth factors.In this study, we loaded tetracycline onto TiO2 nanotubes to demonstrate its antibacterial properties and biocompatibility. The two-layered anodic TiO2 nanotubes with a honeycomb-like porous structure were fabricated by using a two-step (...) anodization, and they were loaded with tetracycline by using a simplified lyophilization method and vacuum drying. Their physical properties, such as chemical compositions, wettability, and surface morphologies of the different samples, were observed and measured by X-ray photoelectron spectroscopy (XPS), contact angle measurement, and scanning electron microscopy (SEM). The in vitro growth behaviors of mouse bone marrow stromal cells (BMSCs) on these substrates were investigated.The TiO2 nanotube (NT

2018 International journal of nanomedicine

37. Application of tetracycline hydrochloride loaded-fungal chitosan and Aloe vera extract based composite sponges for wound dressing Full Text available with Trip Pro

Application of tetracycline hydrochloride loaded-fungal chitosan and Aloe vera extract based composite sponges for wound dressing Chitosan composite material has been used as an efficient drug carrier for potential drug delivery systems in specific cases of wound dressing management. In the present study, 0.5 g/L of the antibiotic tetracycline hydrochloride (TCH) was loaded into 1% fungal chitosan (FCS) incorporated with 0.2% of Aloe vera extract (AVE). Two types of sponges were prepared

2018 Journal of advanced research

38. Solid-Phase Extraction and Large-Volume Sample Stacking-Capillary Electrophoresis for Determination of Tetracycline Residues in Milk Full Text available with Trip Pro

Solid-Phase Extraction and Large-Volume Sample Stacking-Capillary Electrophoresis for Determination of Tetracycline Residues in Milk Solid-phase extraction in combination with large-volume sample stacking-capillary electrophoresis (SPE-LVSS-CE) was applied to measure chlortetracycline, doxycycline, oxytetracycline, and tetracycline in milk samples. Under optimal conditions, the proposed method had a linear range of 29 to 200 µg·L-1, with limits of detection ranging from 18.6 to 23.8 µg·L-1 (...) with inter- and intraday repeatabilities < 10% (as a relative standard deviation) in all cases. The enrichment factors obtained were from 50.33 to 70.85 for all the TCs compared with a conventional capillary zone electrophoresis (CZE). This method is adequate to analyze tetracyclines below the most restrictive established maximum residue limits. The proposed method was employed in the analysis of 15 milk samples from different brands. Two of the tested samples were positive for the presence

2018 Journal of analytical methods in chemistry

39. Live Quantitative Monitoring of Mineral Deposition in Stem Cells Using Tetracycline Hydrochloride Full Text available with Trip Pro

Live Quantitative Monitoring of Mineral Deposition in Stem Cells Using Tetracycline Hydrochloride The final stage of in vitro osteogenic differentiation is characterized by the production of mineral deposits containing calcium cations and inorganic phosphates, which populate the extracellular matrix (ECM) surrounding the cell monolayer. Conventional histological techniques for the assessment of mineralization, such as Von Kossa and Alizarin Red S staining, are end point techniques requiring (...) cell fixation. Moreover, in both cases staining quantitation requires dye extraction, which irreversibly alters the ECM conformation and structure, therefore preventing the use of the sample for further analysis. In this study, the use of tetracycline hydrochloride (TC) is proposed for the nondestructive staining, quantitation, and imaging of mineralizing bone-like nodules in live cultures of human bone marrow mesenchymal stem cells cultured under osteogenic conditions. Overnight administration

2018 Tissue engineering. Part C, Methods

40. Genetic Determinants of Tetracycline Resistance in Clinical Streptococcus pneumoniae Serotype 1 Isolates from Niger Full Text available with Trip Pro

Genetic Determinants of Tetracycline Resistance in Clinical Streptococcus pneumoniae Serotype 1 Isolates from Niger Streptococcus pneumoniae serotype 1 is the first cause of pneumococcal meningitis Niger. To determine the underlying mechanism of resistance to tetracycline in serotype 1 Streptococcus pneumoniae, a collection of 37 isolates recovered from meningitis patients over the period of 2002 to 2009 in Niger were analyzed for drug susceptibility, and whole genome sequencing (WGS (...) ) was performed for molecular analyses. MIC level was determined for 31/37 (83.8%) isolates and allowed detection of full resistance (MIC = 8 µg) in 24/31 (77.4%) isolates. No resistance was found to macrolides and quinolones. Sequence-types deduced from WGS were ST217 (54.1%), ST303 (35.1%), ST2206 (5.4%), ST2839 (2.7%) and one undetermined ST (2.7%). All tetracycline resistant isolates carried a Tn5253 like element, which was found to be an association of two smaller transposons of Tn916 and Tn5252 families

2018 Antibiotics

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>