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1. Recognition and Diagnosis of Sepsis in Rural or Remote Areas: Clinical and Cost-Effectiveness and Guidelines

Recognition and Diagnosis of Sepsis in Rural or Remote Areas: Clinical and Cost-Effectiveness and Guidelines Recognition and Diagnosis of Sepsis in Rural or Remote Areas: Clinical and Cost-Effectiveness and Guidelines | CADTH.ca Find the information you need Recognition and Diagnosis of Sepsis in Rural or Remote Areas: Clinical and Cost-Effectiveness and Guidelines Recognition and Diagnosis of Sepsis in Rural or Remote Areas: Clinical and Cost-Effectiveness and Guidelines Published on: January (...) in adults with suspected sepsis in rural or remote areas? What are the evidence-based guidelines associated with the processes used for the assessment for and recognition of sepsis in adults with suspected sepsis in rural or remote areas? What are the evidence-based guidelines associated with tests used for sepsis diagnosis in adults with suspected sepsis in rural or remote areas? Key Message No literature was identified regarding the clinical effectiveness or cost-effectiveness of processes for tests

2018 Canadian Agency for Drugs and Technologies in Health - Rapid Review

2. Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock

Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock Surviving Sepsis Campaign | SSC Guidelines You may be trying to access this site from a secured browser on the server. Please enable scripts and reload this page. > Guidelines SSC Guidelines Page Content The fourth edition of "Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016​" are linked below. The fifth edition is in development. ESICM and SCCM (...) have announced that the fifth edition update will be completed in collaboration with the group (Guidelines in Intensive Care, Development and Evaluation) affliated with The Research Institute of St. Joseph's Healthcare and McMaster University, Hamilton, Canada. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016​​ Related Materials A User's Guide to the 2016 Surviving Sepsis Guidelines JAMA Viewpoint JAMA Clinical Guidelines Synopsis Practice

2016 Society of Critical Care Medicine

3. Recognition and Diagnosis of Sepsis in Adults: A Review of Evidence-Based Guidelines

Recognition and Diagnosis of Sepsis in Adults: A Review of Evidence-Based Guidelines Recognition and Diagnosis of Sepsis in Adults: A Review of Evidence-Based Guidelines | CADTH.ca Find the information you need Recognition and Diagnosis of Sepsis in Adults: A Review of Evidence-Based Guidelines Recognition and Diagnosis of Sepsis in Adults: A Review of Evidence-Based Guidelines Published on: January 13, 2017 Project Number: RC0841-000 Product Line: Research Type: Other Diagnostics Report Type (...) : Summary with Critical Appraisal Result type: Report Question What are the evidence-based guidelines regarding the use of tests or procedures for the recognition and diagnosis of sepsis in adults with suspected sepsis? Key Message Six evidence-based guidelines were identified for diagnostic tests or processes for the recognition and detection of sepsis in adult populations. Three of these guidelines explored the recognition and detection of sepsis in broader populations, while three others focused

2017 Canadian Agency for Drugs and Technologies in Health - Rapid Review

4. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock Surviving Sepsis Campaign: International Guidelines for Man... : Critical Care Medicine You may be trying to access this site from a secured browser on the server. Please enable scripts and reload this page. Login No user account? Lippincott Journals Subscribers , use your username or email along with your password to log in. Remember me on this computer Register for a free account Registered users can (...) & Issues Collections For Authors Journal Info > > Surviving Sepsis Campaign: International Guidelines for Man... Email to a Colleague Colleague's E-mail is Invalid Your Name: (optional) Your Email: Colleague's Email: Separate multiple e-mails with a (;). Message: Thought you might appreciate this item(s) I saw at Critical Care Medicine. Send a copy to your email Your message has been successfully sent to your colleague. Some error has occurred while processing your request. Please try after some time

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2016 European Respiratory Society

5. Recognition and Diagnosis of Sepsis in Rural or Remote Areas: A Review of Clinical and Cost-Effectiveness and Guidelines

Recognition and Diagnosis of Sepsis in Rural or Remote Areas: A Review of Clinical and Cost-Effectiveness and Guidelines Recognition and Diagnosis of Sepsis in Rural or Remote Areas: A Review of Clinical and Cost-Effectiveness and Guidelines | CADTH.ca Find the information you need Recognition and Diagnosis of Sepsis in Rural or Remote Areas: A Review of Clinical and Cost-Effectiveness and Guidelines Recognition and Diagnosis of Sepsis in Rural or Remote Areas: A Review of Clinical and Cost (...) -Effectiveness and Guidelines Published on: August 11, 2016 Project Number: RC0804-000 Product Line: Research Type: Other Diagnostics Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of processes used for the assessment for and recognition of sepsis in adults with suspected sepsis in rural or remote areas? What is the clinical effectiveness of tests used for sepsis diagnosis in adults with suspected sepsis in rural or remote areas? What is the cost

2016 Canadian Agency for Drugs and Technologies in Health - Rapid Review

6. Survey: There is an urgent need for evidence-based internationally agreed guidelines for the assessment of neonates at risk of developing early-onset sepsis

Survey: There is an urgent need for evidence-based internationally agreed guidelines for the assessment of neonates at risk of developing early-onset sepsis There is an urgent need for evidence-based internationally agreed guidelines for the assessment of neonates at risk of developing early-onset sepsis | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more (...) for the assessment of neonates at risk of developing early-onset sepsis Article Text Child health Survey There is an urgent need for evidence-based internationally agreed guidelines for the assessment of neonates at risk of developing early-onset sepsis Siba Prosad Paul , Kerrie Richardson Statistics from Altmetric.com Commentary on: Mukhopadhyay S, Taylor JA, Von Kohorn I, et al . Variation in sepsis evaluation across a national network of nurseries. Pediatr 2017;139:e20162845. Implications for practice

2018 Evidence-Based Nursing

7. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J‐SSCG 2016) (PubMed)

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J‐SSCG 2016) The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016), a Japanese-specific set of clinical practice guidelines for sepsis and septic shock created jointly by the Japanese Society of Intensive Care Medicine and the Japanese Association for Acute Medicine, was first released in February 2017 in Japanese. An English-language version (...) of these guidelines was created based on the contents of the original Japanese-language version.Members of the Japanese Society of Intensive Care Medicine and the Japanese Association for Acute Medicine were selected and organized into 19 committee members and 52 working group members. The guidelines were prepared in accordance with the Medical Information Network Distribution Service (Minds) creation procedures. The Academic Guidelines Promotion Team was organized to oversee and provide academic support

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2018 Acute medicine & surgery

8. Delay Within the 3-Hour Surviving Sepsis Campaign Guideline on Mortality for Patients With Severe Sepsis and Septic Shock. (PubMed)

Delay Within the 3-Hour Surviving Sepsis Campaign Guideline on Mortality for Patients With Severe Sepsis and Septic Shock. To specify when delays of specific 3-hour bundle Surviving Sepsis Campaign guideline recommendations applied to severe sepsis or septic shock become harmful and impact mortality.Retrospective cohort study.One health system composed of six hospitals and 45 clinics in a Midwest state from January 01, 2011, to July 31, 2015.All adult patients hospitalized with billing (...) diagnosis of severe sepsis or septic shock.Four 3-hour Surviving Sepsis Campaign guideline recommendations: 1) obtain blood culture before antibiotics, 2) obtain lactate level, 3) administer broad-spectrum antibiotics, and 4) administer 30 mL/kg of crystalloid fluid for hypotension (defined as "mean arterial pressure" < 65) or lactate (> 4).To determine the effect of t minutes of delay in carrying out each intervention, propensity score matching of "baseline" characteristics compensated for differences

2018 Critical Care Medicine

9. Incidence and outcomes of sepsis after cardiac surgery as defined by the Sepsis-3 guidelines. (PubMed)

Incidence and outcomes of sepsis after cardiac surgery as defined by the Sepsis-3 guidelines. The Sepsis-3 guidelines diagnose sepsis based on organ dysfunction in patients with either proven or suspected infection. The objective of this study was to assess the incidence and outcomes of sepsis diagnosed using these guidelines in patients in a cardiac intensive care unit (CICU) after cardiac surgery.Daily sequential organ failure assessment (SOFA) scores were calculated for 2230 consecutive (...) diagnoses were based on proven infection and half on suspected infection. Patients diagnosed with sepsis using the Sepsis-3 guidelines have significantly worse outcomes after cardiac surgery. The Sepsis-3 guidelines are a potentially useful tool in the management of sepsis following cardiac surgery.Copyright © 2017 British Journal of Anaesthesia. All rights reserved.

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2018 British Journal of Anaesthesia

10. Empiric Antibiotic Treatment Reduces Mortality in Severe Sepsis and Septic Shock From the First Hour: Results From a Guideline-Based Performance Improvement Program

Empiric Antibiotic Treatment Reduces Mortality in Severe Sepsis and Septic Shock From the First Hour: Results From a Guideline-Based Performance Improvement Program PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2015 PedsCCM Evidence-Based Journal Club

11. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. (PubMed)

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. To provide an update to "Surviving Sepsis Campaign Guidelines for Management of Sepsis and Septic Shock: 2012."A consensus committee of 55 international experts representing 25 international organizations was convened. Nominal groups were assembled at key international meetings (for those committee members attending the conference). A formal conflict-of-interest (COI) policy was developed (...) generated. Each subgroup generated a list of questions, searched for best available evidence, and then followed the principles of the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system to assess the quality of evidence from high to very low, and to formulate recommendations as strong or weak, or best practice statement when applicable.The Surviving Sepsis Guideline panel provided 93 statements on early management and resuscitation of patients with sepsis or septic shock

2017 Critical Care Medicine

12. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. (PubMed)

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. To provide an update to "Surviving Sepsis Campaign Guidelines for Management of Sepsis and Septic Shock: 2012".A consensus committee of 55 international experts representing 25 international organizations was convened. Nominal groups were assembled at key international meetings (for those committee members attending the conference). A formal conflict-of-interest (COI) policy was developed (...) generated. Each subgroup generated a list of questions, searched for best available evidence, and then followed the principles of the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system to assess the quality of evidence from high to very low, and to formulate recommendations as strong or weak, or best practice statement when applicable.The Surviving Sepsis Guideline panel provided 93 statements on early management and resuscitation of patients with sepsis or septic shock

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2017 Intensive Care Medicine

13. The impact of evidence-based sepsis guidelines on emergency department clinical practice: a pre-post medical record audit. (PubMed)

The impact of evidence-based sepsis guidelines on emergency department clinical practice: a pre-post medical record audit. To explore the number of patients presenting with sepsis before and after guideline implementation; the impact of sepsis guidelines on triage assessment, emergency department management and time to antibiotics.Sepsis remains one of the leading causes of mortality and morbidity within hospitals. Globally, strategies have been implemented to reduce morbidity and mortality (...) rates, which rely on the early recognition and management of sepsis. To improve patient outcomes, the New South Wales government in Australia introduced sepsis guidelines into emergency departments. However, the impact of the guidelines on clinical practice remains unclear.A 12-month pre-post retrospective randomised medical record audit of adult patients with a sepsis diagnosis. Data were extracted from the emergency department database and paper medical record. Data included patient demographic

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2018 Journal of clinical nursing

14. Variation in Emergency Department Adherence to Treatment Guidelines for Inpatient Pneumonia and Sepsis: A Retrospective Cohort Study. (PubMed)

Variation in Emergency Department Adherence to Treatment Guidelines for Inpatient Pneumonia and Sepsis: A Retrospective Cohort Study. Evidence-based clinical practice guidelines (CPGs) for the treatment of pneumonia and sepsis have existed for many years with multiple studies suggesting improved patient outcomes. Despite their importance, little is known about variation in emergency department (ED) adherence to these CPGs. Our objectives were to estimate variation in ED adherence across CPGs (...) for pneumonia and sepsis and identify patient, provider, and environmental factors associated with adherence.This was a multicenter retrospective study using standard medical record review methods. The population consisted of consecutive adults hospitalized for pneumonia or sepsis (identified by discharge ICD-9 codes) at five Colorado hospitals (two academic, three community) who were admitted to the hospital from the ED and for whom the ED diagnosed or initiated treatment. The outcome measured was ED

2018 Academic Emergency Medicine

15. Poor Compliance with Sepsis Guidelines in a Tertiary Care Children’s Hospital Emergency Room (PubMed)

Poor Compliance with Sepsis Guidelines in a Tertiary Care Children’s Hospital Emergency Room This study aimed to assess factors related to adherence to the Pediatric Advanced Life Support guidelines for severe sepsis and septic shock in an emergency room (ER) of a tertiary care children's hospital.This was a retrospective, observational study of children (0-18 years old) in The Children's Hospital of San Antonio ER over 1 year with the International Consensus Definition Codes, version-9 (ICD (...) -9) diagnostic codes for "severe sepsis" and "shocks." Patients in the adherent group were those who met all three elements of adherence: (1) rapid vascular access with at most one IV attempt before seeking alternate access (unless already in place), (2) fluids administered within 15 min from sepsis recognition, and (3) antibiotic administration started within 1 h of sepsis recognition. Comparisons between groups with and without sepsis guideline adherence were performed using Student's t-test

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2018 Frontiers in pediatrics

16. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016) (PubMed)

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016) The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016), a Japanese-specific set of clinical practice guidelines for sepsis and septic shock created jointly by the Japanese Society of Intensive Care Medicine and the Japanese Association for Acute Medicine, was first released in February 2017 and published in the Journal of JSICM, [2017; Volume 24 (...) and organized into 19 committee members and 52 working group members. The guidelines were prepared in accordance with the Medical Information Network Distribution Service (Minds) creation procedures. The Academic Guidelines Promotion Team was organized to oversee and provide academic support to the respective activities allocated to each Guideline Creation Team. To improve quality assurance and workflow transparency, a mutual peer review system was established, and discussions within each team were open

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2018 Journal of intensive care

17. Reviewing the WHO guidelines for antibiotic use for sepsis in neonates and children (PubMed)

Reviewing the WHO guidelines for antibiotic use for sepsis in neonates and children Background Guidelines from 2005 for treating suspected sepsis in low- and middle-income countries (LMIC) recommended hospitalisation and prophylactic intramuscular (IM) or intravenous (IV) ampicillin and gentamicin. In 2015, recommendations when referral to hospital is not possible suggest the administration of IM gentamicin and oral amoxicillin. In an era of increasing antimicrobial resistance, an updated (...) review of the appropriate empirical therapy for treating sepsis (taking into account susceptibility patterns, cost and risk of adverse events) in neonates and children is necessary. Methods Systematic literature review and international guidelines were used to identify published evidence regarding the treatment of (suspected) sepsis. Results Five adequately designed and powered studies comparing antibiotic treatments in a low-risk community in neonates and young infants in LMIC were identified

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2018 Paediatrics and international child health

18. Effect of Audit and Feedback on Physician Adherence to Clinical Practice Guidelines for Pneumonia and Sepsis. (PubMed)

Effect of Audit and Feedback on Physician Adherence to Clinical Practice Guidelines for Pneumonia and Sepsis. The objective was to estimate the effect of feedback with blinded peer comparison on emergency physician adherence to guidelines for appropriate antibiotic administration for inpatient pneumonia and completion of the 3-hour Surviving Sepsis Bundle for severe sepsis. The authors performed a quasi-experiment using a stepped wedge design at a single urban safety net hospital. Attending (...) emergency physicians were randomized into 6 clusters. Once a cluster crossed into the intervention group, physicians in that cluster began receiving detailed feedback with blinded peer comparison on their adherence to guidelines for pneumonia and sepsis. Feedback with blinded peer comparison significantly improved guideline adherence from 52% without feedback to 65% with feedback (difference = 13%, 95% confidence interval = 4% to 22%). In adjusted analyses, the odds of providing guideline adherent care

2018 American Journal of Medical Quality

19. Guideline developers are not the only experts: Utilising the FRAM method in sepsis pathways. (PubMed)

Guideline developers are not the only experts: Utilising the FRAM method in sepsis pathways. Improving clinical outcomes and quality of care in diseases such as sepsis, which are heterogeneous in their presenting signs and symptoms, is a challenge. One approach is to utilise the Functional Analysis Resonance Method (FRAM), which enables systems to examine process and sociocontextual issues in treatment and management pathways. McNab et al. applied FRAM to group of primary care (family (...) ) practices to understand the barriers and enablers in the management of sepsis and determined a suite of possible interventions that might improve patient care. This commentary reviews the FRAM process and highlights some core issues for systems to consider when tackling diseases like sepsis.Please see related article: https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-018-1164-x.

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2018 BMC Medicine

20. Petition to retire the surviving sepsis campaign guidelines. A #FOAMed Movement.

Petition to retire the surviving sepsis campaign guidelines. A #FOAMed Movement. Petition to retire the surviving sepsis campaign guidelines. A #FOAMed Movement. | thinking critical care Menu Hello to all. Below is a coordinated effort from many of us to repeal the un-physiological and sub-optimal recommendations of the SSC Guidelines. Although potentially helpful in certain cases and situations where expertise is lacking, the consequences of mandating such protocols across the board (...) is worrisome. Please consider the issue and join us. Philippe Friends, Concern regarding the Surviving Sepsis Campaign (SSC) guidelines dates back to their inception. Guideline development was sponsored by Eli Lilly and Edwards Life Sciences as part of a commercial marketing campaign (1). Throughout its history, the SSC has a track record of conflicts of interest, making strong recommendations based on weak evidence, and being poorly responsive to new evidence (2-6). The original backbone of the guidelines

2018 Thinking critical care blog

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