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1. Omega-3 fatty acid supplementation for cystic fibrosis. (Abstract)

Omega-3 fatty acid supplementation for cystic fibrosis. Studies suggest that a diet rich in omega-3 essential fatty acids may have beneficial anti-inflammatory effects for chronic conditions such as cystic fibrosis. This is an updated version of a previously published review.To determine whether there is evidence that omega-3 polyunsaturated fatty acid supplementation reduces morbidity and mortality and to identify any adverse events associated with supplementation.We searched the Cochrane (...) Cystic Fibrosis and Genetic Disorders Group's Trials Register comprising references identified from comprehensive electronic database searches and handsearches of relevant journals and abstract books of conference proceedings. Date of last search: 01 April 2020. We also searched online study registries and contacted authors. Date of last search: 12 February 2020.Randomised controlled trials in people with cystic fibrosis comparing omega-3 fatty acid supplements with placebo.Two authors independently

2020 Cochrane

2. Somethin’ Fishy: Prescription variants of Omega-3 to prevent cardiovascular disease

Somethin’ Fishy: Prescription variants of Omega-3 to prevent cardiovascular disease November 16, 2020 Somethin’ Fishy: Prescription variants of Omega-3 to prevent cardiovascular disease Clinical Question: Do prescription variants of omega-3’s, like icosapent, reduce the risk of cardiovascular events when added to statins? Bottom Line: In high risk patients, icosapent reduced cardiovascular events to 17% from 22% on placebo after 5 years. In lower risk patients, Eicosapentaenoic Acid (EPA) ethyl (...) ester reduced major cardiovascular events to 2.8% from 3.5% with control after 5 years. Whether these products differ from each other or traditional omega-3 fatty acids (that don’t show cardiovascular benefit) is unknown. Cost will likely limit use. Evidence: • Focusing on patient-oriented outcomes from large randomized controlled trials (RCTs) where prescription EPA products were added to statins. o Icosapent: ? REDUCE-IT: 1 8179 patients (70% secondary prevention), randomized to icosapent 2g twice

2021 Tools for Practice

3. Omega-3 and omega-6 polyunsaturated fatty acids for dry eye disease. Full Text available with Trip Pro

Omega-3 and omega-6 polyunsaturated fatty acids for dry eye disease. Polyunsaturated fatty acid (PUFA) supplements, involving omega-3 and/or omega-6 components, have been proposed as a therapy for dry eye. Omega-3 PUFAs exist in both short- (alpha-linolenic acid [ALA]) and long-chain (eicosapentaenoic acid [EPA] and docosahexaenoic acid [DHA]) forms, which largely derive from certain plant- and marine-based foods respectively. Omega-6 PUFAs are present in some vegetable oils, meats, and other (...) animal products.To assess the effects of omega-3 and omega-6 polyunsaturated fatty acid (PUFA) supplements on dry eye signs and symptoms.CENTRAL, Medline, Embase, two other databases and three trial registries were searched in February 2018, together with reference checking. A top-up search was conducted in October 2019, but the results have not yet been incorporated.We included randomized controlled trials (RCTs) involving dry eye participants, in which omega-3 and/or omega-6 supplements were

2019 Cochrane

4. Preoperative use of omega-3 fatty acids or vitamin E

Preoperative use of omega-3 fatty acids or vitamin E Preoperative use of omega-3 fatty acids or vitamin E We use cookies on this website. By using this site, you agree that we may store and access cookies on your device. Swedish Agency for Health Technology Assessment and Assessment of Social Services Preoperative use of omega-3 fatty acids or vitamin E Share: Reading time approx. 1 minute Both omega-3 fatty acids and vitamin E are common in food supplements. Omega-3 are polyunsaturated fatty (...) acids present in example given marine oils while vitamin E is a fat soluble antioxidant. Question Can food supplements containing omega-3 fatty acids or vitamin E increase bleeding risk and should therefore be avoided during a period before a surgical intervention? Identified literature 1. Xin W, Wei W, Lin Z, Zhang X, Yang H, Zhang T, et al. Fish oil and atrial fibrillation after cardiac surgery: a meta-analysis of randomized controlled trials. PloS one. 2013;8(9):e72913. 2. Begtrup KM, Krag AE

2018 Swedish Council on Technology Assessement

5. Omega-3 fatty acid supplementation in pregnancy-baseline omega-3 status and early preterm birth: exploratory analysis of a randomised controlled trial. (Abstract)

Omega-3 fatty acid supplementation in pregnancy-baseline omega-3 status and early preterm birth: exploratory analysis of a randomised controlled trial. To identify a polyunsaturated fatty acid (PUFA) biomarker able to detect which women with singleton pregnancies are most likely to benefit from omega-3 supplementation to reduce their risk of early preterm birth.Exploratory analysis of a randomised controlled trial.Six Australian hospitals.Women with a singleton pregnancy enrolled in the ORIP (...) trial.Using maternal capillary whole blood collected ~14 weeks' gestation, the fatty acids in total blood lipids were quantified using gas chromatography. Interaction tests examined whether baseline PUFA status modified the effect of omega-3 supplementation on birth outcomes.Early preterm birth (<34 weeks' gestation).A low total omega-3 PUFA status in early pregnancy was associated with a higher risk of early preterm birth. Among women with a total omega-3 status ≤4.1% of total fatty acids, omega-3

2020 BJOG

6. Omega-3 Fatty Acids for the Management of Hypertriglyceridemia: A Science Advisory From the American Heart Association Full Text available with Trip Pro

Omega-3 Fatty Acids for the Management of Hypertriglyceridemia: A Science Advisory From the American Heart Association Omega-3 Fatty Acids for the Management of Hypertriglyceridemia: A Science Advisory From the American Heart Association | Circulation Search Hello Guest! Login to your account Email Password Keep me logged in Search December 2019 November 2019 October 2019 September 2019 August 2019 July 2019 June 2019 May 2019 April 2019 March 2019 February 2019 January 2019 This site uses (...) cookies. By continuing to browse this site you are agreeing to our use of cookies. Free Access article Share on Jump to Free Access article Omega-3 Fatty Acids for the Management of Hypertriglyceridemia: A Science Advisory From the American Heart Association , PhD , MD, FAHA, Chair , PhD, FAHA , MD, FAHA , PhD, RD, FAHA , PhD , MD, FAHA , PhD, RN, FAHA , MD, FAHA , MD, MPH, FAHA , MD, FAHA , MD, PhD , MD, MPH, FAHA , MD, PhD, FAHA Ann C. Skulas-Ray , Peter W.F. Wilson , William S. Harris , Eliot

2019 American Heart Association

7. Is there evidence to support the use of omega-3 fatty acids in preventing cardiovascular events?

Is there evidence to support the use of omega-3 fatty acids in preventing cardiovascular events? Is There Evidence to Support the Use of Omega-3 Fatty Acids in Preventing Cardiovascular Events? – Clinical Correlations Search Is There Evidence to Support the Use of Omega-3 Fatty Acids in Preventing Cardiovascular Events? May 24, 2019 8 min read By Lily Cao Peer Reviewed A quick web search would suggest countless reasons to take fish oil, a supplement that Americans have fallen in love (...) with. In 2012, fish oil, which is composed of two omega-3 fatty acids–eicosapentaenoic acid (EPA) and docasahexaenoic acid (DHA)—was the natural product most commonly used by US adults, with nearly 20 million Americans taking the supplement. 1 The potential health benefit of fish oil was first postulated in the 1970s by Danish scientists visiting an Inuit village in Greenland. The scientists discovered that the villagers, who ate a diet rich in omega-3 fatty acids, had lower levels of cholesterol

2019 Clinical Correlations

8. Is there evidence to support the use of omega-3 fatty acids in preventing cardiovascular events?

Is there evidence to support the use of omega-3 fatty acids in preventing cardiovascular events? Is there evidence to support the use of omega-3 fatty acids in preventing cardiovascular events? – Clinical Correlations Search Is there evidence to support the use of omega-3 fatty acids in preventing cardiovascular events? October 17, 2019 8 min read By Lily Cao Peer Reviewed A quick web search would suggest countless reasons to take fish oil, a supplement that Americans have fallen in love (...) with. In 2012, fish oil, which is composed of two omega-3 fatty acids–eicosapentaenoic acid (EPA) and docasahexaenoic acid (DHA)—was the natural product . 1 The potential health benefit of fish oil was first postulated in the 1970s by Danish scientists visiting an Inuit village in Greenland. The scientists discovered that the villagers, who ate a diet rich in omega-3 fatty acids, had lower levels of cholesterol and triglycerides compared to the Danish population. Early scientific studies went on to further

2019 Clinical Correlations

9. Supplementation with the omega-3 long chain polyunsaturated fatty acids: Changes in the concentrations of omega-3 index, fatty acids and molecular phospholipids of people at ultra high risk of developing psychosis. (Abstract)

Supplementation with the omega-3 long chain polyunsaturated fatty acids: Changes in the concentrations of omega-3 index, fatty acids and molecular phospholipids of people at ultra high risk of developing psychosis. Omega-3 long chain polyunsaturated fatty acids (n-3 LCPUFA) are necessary for optimum mental health, with recent studies showing low n-3 LCPUFA in people at ultra-high risk (UHR) of developing psychosis. Furthermore, people at UHR of psychosis had increased erythrocyte sphingomyelin

2019 Schizophrenia Research

10. Omega-3 Supplements for Dry Eye: Fishy evidence or a big catch?

Omega-3 Supplements for Dry Eye: Fishy evidence or a big catch? Tools for Practice is proudly sponsored by the Alberta College of Family Physicians (ACFP). ACFP is a provincial, professional voluntary organization, representing more than 4,800 family physicians, family medicine residents, and medical students in Alberta. Established over sixty years ago, the ACFP strives for excellence in family practice through advocacy, continuing medical education and primary care research. www.acfp.ca (...) September 10, 2018 Omega-3 Supplements for Dry Eye: Fishy evidence or a big catch? Clinical Question: Does oral omega-3 supplementation improve symptoms of dry eye disease? Bottom Line: The evidence for omega-3 is inconsistent. The best quality randomized control trial (RCT) found that omega-3 supplementation does not improve dry eye symptoms or function. Smaller RCTs suggest statistically significant benefits in symptom scores that are not always clinically relevant. At best, omega-3 will improve

2018 Tools for Practice

12. Effect of omega 3 fatty acids intake during pregnancy on maternal health and birth outcomes: A Meta-Analysis and meta-analysis Full Text available with Trip Pro

Effect of omega 3 fatty acids intake during pregnancy on maternal health and birth outcomes: A Meta-Analysis and meta-analysis Effect of omega 3 fatty acids intake during pregnancy on maternal health and birth outcomes: A Meta-Analysis and meta-analysis - Authorea "); } "); } "); } "); } "); } "); } "); } AUTHOREA loading page this is for holding javascript data Effect of omega 3 fatty acids intake during pregnancy on maternal health and birth outcomes: A Meta-Analysis and meta-analysis +3 Mona (...) Abdelrahman , Hasnaa Osama , Haitham Saeed , Yasmin Madney , Hadeer Harb , Mohamed Abdelrahim Mona Abdelrahman Beni Suef University Hasnaa Osama Beni Suef University Haitham Saeed Beni Suef University Yasmin Madney Beni Suef University Hadeer Harb Beni Suef University Mohamed Abdelrahim Beni Suef University Abstract Background: It is assumed that the intake of omega 3 polyunsaturated fatty acids (PUFAs) during pregnancy is vital to maternal health and fetal growth. Objective: The objective was to examine

2020 Authorea, Inc.

13. Efficacy and safety of omega-3 fatty acids on liver-related outcomes in patients with nonalcoholic fatty liver disease: a protocol for a systematic review and meta-analysis Full Text available with Trip Pro

Efficacy and safety of omega-3 fatty acids on liver-related outcomes in patients with nonalcoholic fatty liver disease: a protocol for a systematic review and meta-analysis Inplasy Protocol 241 - INPLASY.COM International Platform of Registered Systematic Review and Meta-analysis Protocols Main Menu Share this: Copyright © 2021 INPLASY.COM Powered by INPLASY.COM

2020 International Platform of Registered Systematic Review and Meta-analysis Protocols

14. Does omega-3 lower blood pressure? a protocol for systematic review and meta-analysis Full Text available with Trip Pro

Does omega-3 lower blood pressure? a protocol for systematic review and meta-analysis Inplasy Protocol 567 - INPLASY.COM International Platform of Registered Systematic Review and Meta-analysis Protocols Main Menu Share this: Copyright © 2021 INPLASY.COM Powered by INPLASY.COM

2020 INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols

15. Dietary interventions with or without omega-3 supplementation for the management of rheumatoid arthritis: a systematic review protocol Full Text available with Trip Pro

Dietary interventions with or without omega-3 supplementation for the management of rheumatoid arthritis: a systematic review protocol Dietary interventions with or without omega-3... | HRB Open Research ') search clear search menu close clear Search Dietary interventions with or without omega-3 supplementation for... ALL Metrics - Views Downloads How to cite this article Raad T, George E, Griffin A et al. Dietary interventions with or without omega-3 supplementation for the management (...) to you. A full article citation will be automatically included. SEND EMAIL ▬ ✚ Study Protocol Dietary interventions with or without omega-3 supplementation for the management of rheumatoid arthritis: a systematic review protocol [version 1; peer review: awaiting peer review] https://orcid.org/0000-0002-2261-9061 1 , Elena George https://orcid.org/0000-0002-1385-2371 2 , Anne Griffin https://orcid.org/0000-0002-1581-2998 1 , Louise Larkin 3 , Alexander Fraser 4,5 , Norelee Kennedy 3 , Audrey Tierney

2020 HRB open research

16. Omega-3 fatty acids for the treatment of dementia. Full Text available with Trip Pro

Omega-3 fatty acids for the treatment of dementia. Omega-3 polyunsaturated fatty acids (omega-3 PUFAs) from fish and plant sources are commonly considered as a promising non-medical alternative to improve brain functions and slow down the progression of dementia. This assumption is mostly based on findings of preclinical studies and epidemiological research. Resulting explanatory models aim at the role omega-3 PUFAs play in the development and integrity of the brain's neurons, their protective (...) antioxidative effect on cell membranes and potential neurochemical mechanisms directly related to Alzheimer-specific pathology. Epidemiological research also found evidence of malnutrition in people with dementia. Considering this and the fact that omega-3 PUFA cannot be synthesised by humans, omega-3 PUFAs might be a promising treatment option for dementia.To assess the efficacy and safety of omega-3 polyunsaturated fatty acid (PUFA) supplementation for the treatment of people with dementia.We searched

2016 Cochrane

17. Omega-3 fatty acid supplements

Omega-3 fatty acid supplements Omega-3 fatty acid supplements | Advice | NICE Omega-3 fatty acid supplements Key therapeutic topic [KTT4] Published date: January 2015 Advice The key therapeutic topic omega-3 fatty acid supplements has been incorporated into the key therapeutic topic lipid-modifying drugs . See for more information. Explore © NICE [year]. All rights reserved. Subject to .

2015 National Institute for Health and Clinical Excellence - Advice

18. Omega-3 supplementation and cardiovascular disease: formulation-based systematic review and meta-analysis with trial sequential analysis

Omega-3 supplementation and cardiovascular disease: formulation-based systematic review and meta-analysis with trial sequential analysis Omega-3 supplementation and cardiovascular disease: formulation-based systematic review and meta-analysis with trial sequential analysis - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 (...) ahead of print. Omega-3 supplementation and cardiovascular disease: formulation-based systematic review and meta-analysis with trial sequential analysis # , # , , , Affiliations Expand Affiliations 1 Department of Internal Medicine, University Hospital of Ioannina, Ioannina, Greece. 2 School of Medicine, European University of Cyprus, Nicosia, Cyprus. 3 Evidence-Based Medicine Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece. 4 Clinical

2020 EvidenceUpdates

19. Lack of benefit with omega-3 fatty acid supplementation in HIV patients: A randomized pilot study. (Abstract)

Lack of benefit with omega-3 fatty acid supplementation in HIV patients: A randomized pilot study. Objective: To assess the effect of omega-3 polyunsaturated fatty acids (n-3 PUFA) supplementation on bone metabolism in HIV-infected patients presenting with hypertriglyceridemia. Methods: Patients were randomized 1:1 to receive 2 g of n-3 PUFA or fenofibrate (FF). The primary endpoint was % change in bone mineral density (BMD) from baseline to month 24 in lumbar spine (LS) and femoral neck (FN (...) ). There was a significant difference in calcitriol changes between arms after 96 weeks. No differences in Z-score or bone turnover markers were observed between the two arms. Conclusions: Omega-3 fatty acid supplementation resulted in no beneficial changes in BMD or bone turnover markers. n-3 PUFA supplementation achieved similar reductions in triglyceride levels as FF.

2019 HIV research & clinical practice Controlled trial quality: uncertain

20. Effects of omega-3 fatty acids supplementation on neoadjuvant chemotherapy-induced toxicity in patients with locally advanced breast cancer: a randomized, controlled, double-blinded clinical trial. Full Text available with Trip Pro

Effects of omega-3 fatty acids supplementation on neoadjuvant chemotherapy-induced toxicity in patients with locally advanced breast cancer: a randomized, controlled, double-blinded clinical trial. Background: antineoplastic treatment for locally advanced breast cancer (LABC) includes neodjuvant chemotherapy (NeoCT). However, side effects occur frequently, affecting the functional capacity and quality of life of patients as a result of the proinflammatory state of this therapy. In this work (...) , omega-3 polyunsaturated fatty acids (PUFA Ω-3) were administered as they have been reported to modulate some molecular pathways such as nuclear factor-kappa B (NF-κB), which is associated with toxicity secondary to the administration of anthracyclines. Objective: to evaluate the effects of PUFA Ω-3 on the toxicity, side effects, body composition, cardiometabolic profile and quality of life in women with LABC after NeoCT. Methods: fifty-three women with LABC were included in a double-blinded, placebo

2019 Nutricion hospitalaria Controlled trial quality: predicted high

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