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1. Neonatal parenteral nutrition

://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 4 of 52Overview Overview This guideline covers parenteral nutrition (intravenous feeding) for babies born preterm, up to 28 days after their due birth date and babies born at term, up to 28 days after their birth. Parenteral nutrition is often needed by preterm babies, critically ill babies, and babies who need surgery. Who is it for? Who is it for? • Healthcare professionals who care for newborn babies • Commissioners and providers of neonatal (...) Neonatal parenteral nutrition Neonatal parenteral nutrition NICE guideline Published: 26 February 2020 www.nice.org.uk/guidance/ng154 © NICE 2020. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Your responsibility Your responsibility The recommendations in this guideline represent the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, professionals and practitioners

2020 National Institute for Health and Clinical Excellence - Clinical Guidelines

2. Specialist neonatal respiratory care for babies born preterm

babies requiring respiratory support? Morphine Morphine What is the effectiveness of morphine compared with containment holding for preterm babies receiving respiratory support? In Inv volving parents and carers olving parents and carers What is the impact of parental involvement as part of Family integrated care (FIC) or the Newborn individualised developmental care and assessment programme (NIDCAP ® ) on the incidence of BPD and length of hospital stay in preterm babies? Specialist neonatal (...) Specialist neonatal respiratory care for babies born preterm Specialist neonatal respir Specialist neonatal respiratory care for atory care for babies born preterm babies born preterm NICE guideline Published: 3 April 2019 nice.org.uk/guidance/ng124 © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Y Y our responsibility our responsibility The recommendations in this guideline represent the view of NICE, arrived

2019 National Institute for Health and Clinical Excellence - Clinical Guidelines

3. COVID-19 - guidance for neonatal settings

enters the room. Intubation of the mother for a GA Caesarean section is a significant aerosol generating procedure (AGP); the use of Entonox and maternal pushing during labour are not considered AGPs. Suctioning, bag mask ventilation and intubation of the newborn are AGPs, although the absolute risk to health care workers performing these manoeuvres on newborn infants is thought to be low. Commonly used equipment for neonatal resuscitation and stabilisation should be readily available (eg located (...) place as usual Audiology screening should continue in maternity units and on the NNU if staffing resources permit. The ability to perform investigations and tests once the infant has left hospital will be restricted - eg newborn hearing screening in the community, bringing infants back for echocardiograms, etc. Thus, where possible, investigations and tests should be performed before discharge from the maternity or neonatal unit. Maternity units should aim to maintain sufficient staffing in order

2020 Royal College of Paediatrics and Child Health

4. Enteral lactoferrin for the treatment of sepsis and necrotizing enterocolitis in neonates. (Abstract)

Enteral lactoferrin for the treatment of sepsis and necrotizing enterocolitis in neonates. Neonatal sepsis and necrotizing enterocolitis (NEC) cause significant neonatal mortality and morbidity despite appropriate antibiotic therapy. Enhancing host defense and modulating inflammation by using lactoferrin as an adjunct to antibiotics in the treatment of sepsis, NEC, or both, may improve clinical outcomes.The primary objective was to assess safety and efficacy of oral lactoferrin as an adjunct (...) to antibiotics in the treatment of neonates with suspected or confirmed sepsis, NEC, or both.We used the standard search strategy of Cochrane Neonatal to search the Cochrane Central Register of Controlled Trials (CENTRAL 2018, Issue 9), MEDLINE via PubMed, PREMEDLINE, (1966 to 20 September 2018) Embase (1980 to 20 September 2018), and CINAHL (1982 to 20 September 2018). We also searched clinical trial databases, conference proceedings, the reference lists of retried articles and clinical trials

2019 Cochrane

5. Prebiotics for the prevention of hyperbilirubinaemia in neonates. (Abstract)

Prebiotics for the prevention of hyperbilirubinaemia in neonates. Hyperbilirubinaemia occurs in approximately two-thirds of all newborns during the first days of life and is frequently treated with phototherapy. Although generally seen as safe, there is rising concern regarding phototherapy and its potentially damaging effects on DNA and increased side effects particularly for preterm infants. Other methods, such as enteral feeding supplementation with prebiotics, may have an effective use (...) in the management of hyperbilirubinaemia in neonates.To determine whether administration of prebiotics reduces the incidence of hyperbilirubinaemia among term and preterm infants compared with enteral supplementation of milk with distilled water/placebo or no supplementation.We used the standard search strategy of Cochrane Neonatal to search the Cochrane Central Register of Controlled Trials (CENTRAL 2018, Issue 5), MEDLINE via PubMed (1966 to 14 June 2018), Embase (1980 to 14 June 2018), and CINAHL (1982 to 14

2019 Cochrane

6. Prostanoids and their analogues for the treatment of pulmonary hypertension in neonates. (Abstract)

Prostanoids and their analogues for the treatment of pulmonary hypertension in neonates. Persistent pulmonary hypertension of the newborn (PPHN) is a disease entity that describes a physiology in which there is persistence of increased pulmonary arterial pressure. PPHN is characterised by failure to adapt to a functional postnatal circulation with a fall in pulmonary vascular resistance. PPHN is responsible for impairment in oxygenation and significant neonatal mortality and morbidity (...) . Prostanoids and their analogues may be useful therapeutic interventions due to their pulmonary vasodilatory and immunomodulatory effects.Primary objective• To determine the efficacy and safety of prostanoids and their analogues (iloprost, treprostinil, and beraprost) in decreasing mortality and the need for extracorporeal membrane oxygenation (ECMO) among neonates with PHSecondary objective• To determine the efficacy and safety of prostanoids and their analogues (iloprost, treprostinil, and beraprost

2019 Cochrane

7. Neonatal jaundice

Neonatal jaundice Neonatal jaundice - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Neonatal jaundice Last reviewed: February 2019 Last updated: January 2019 Summary Usually noted clinically when serum bilirubin is >85.5 micromol/L (5 mg/dL). Occurs in 50% to 70% of term neonates. Most cases physiological. Jaundice in the first 24 hours of life is considered pathological. Treatment for severe hyperbilirubinaemia (...) includes phototherapy and/or exchange transfusion. The major complication of unconjugated hyperbilirubinaemia is kernicterus. Definition Neonatal jaundice is the yellowing discoloration of the skin and sclera of a neonate, which is caused by increased levels of bilirubin in the blood. A neonate refers to an infant in the first 28 days of life. This topic focuses on recognising and managing early neonatal jaundice, which is most commonly caused by unconjugated hyperbilirubinaemia. While prolonged

2019 BMJ Best Practice

8. Checklist: Neonatal stabilisation for retrieval, Preparation for neonatal retrieval

Checklist: Neonatal stabilisation for retrieval, Preparation for neonatal retrieval Queensland Health State of Queensland (Queensland Health) 2018 http://creativecommons.org/licenses/by-nc-nd/3.0/au/deed.en Queensland Clinical Guidelines, Guidelines@health.qld.gov.au Queensland Clinical Guidelines www.health.qld.gov.au/qcg Checklist: Preparation for neonatal retrieval You may not be able to do anything else to improve the baby’s condition other than keeping the baby stable and preventing (...) monitoring (cardiorespiratory and oxygen saturation) ? Analgesia and/or sedation administered either intravenous or oral as required ? Appropriate care initiated: ? Neurodevelopment (positioning, lighting and noise reduction) ? Skin ? Retrieval service advised of changes to baby’s condition that may affect ongoing care or transport logistics ?3. Documentation (2 copies): ? Referral letter (including maternal obstetric history and reason for transfer) ? Neonatal medical/nursing notes ? Neonatal

2018 Queensland Health

10. Bacillus Calmette–Guérin Vaccine Dosage Timing for Neonates in the NICU: Safety and Guidelines

Bacillus Calmette–Guérin Vaccine Dosage Timing for Neonates in the NICU: Safety and Guidelines Bacillus Calmette–Guérin Vaccine Dosage Timing for Neonates in the NICU: Safety and Guidelines | CADTH.ca Find the information you need Bacillus Calmette–Guérin Vaccine Dosage Timing for Neonates in the NICU: Safety and Guidelines Bacillus Calmette–Guérin Vaccine Dosage Timing for Neonates in the NICU: Safety and Guidelines Last updated: February 19, 2019 Project Number: RA1010-000 Product Line (...) : Research Type: Devices and Systems Report Type: Reference List Result type: Report Question What is the comparative safety of differing Bacillus Calmette-Guérin vaccine timing for neonates in or discharged from the neonatal intensive care unit? What are the evidence-based guidelines for Bacillus Calmette-Guérin vaccine timing for neonates in or discharged from the neonatal intensive care unit? Key Message No relevant clinical evidence was identified regarding the comparative safety of differing

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

11. Treatment of Neonatal Abstinence Syndrome due to Crystal Methamphetamine: A Review of Clinical Effectiveness and Guidelines

Treatment of Neonatal Abstinence Syndrome due to Crystal Methamphetamine: A Review of Clinical Effectiveness and Guidelines Treatment of Neonatal Abstinence Syndrome due to Crystal Methamphetamine: A Review of Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Treatment of Neonatal Abstinence Syndrome due to Crystal Methamphetamine: A Review of Clinical Effectiveness and Guidelines Treatment of Neonatal Abstinence Syndrome due to Crystal Methamphetamine: A Review (...) of Clinical Effectiveness and Guidelines Last updated: June 7, 2019 Project Number: RC1129-000 Product Line: Research Type: Devices and Systems Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of interventions for the treatment of neonatal abstinence syndrome due to crystal methamphetamine? What is the comparative clinical effectiveness of tools for the diagnosis and monitoring of neonatal abstinence syndrome due to crystal methamphetamine? What

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

12. Trimmed Peripherally Inserted Central Catheters for Hospitalized Neonatal Patients: A Review of Safety and Guidelines

Trimmed Peripherally Inserted Central Catheters for Hospitalized Neonatal Patients: A Review of Safety and Guidelines Trimmed Peripherally Inserted Central Catheters for Hospitalized Neonatal Patients: A Review of Safety and Guidelines | CADTH.ca Find the information you need Trimmed Peripherally Inserted Central Catheters for Hospitalized Neonatal Patients: A Review of Safety and Guidelines Trimmed Peripherally Inserted Central Catheters for Hospitalized Neonatal Patients: A Review of Safety (...) and Guidelines Last updated: September 26, 2019 Project Number: RC1191-000 Product Line: Research Type: Devices and Systems Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical safety of trimmed peripherally inserted central catheters among hospitalized neonatal patients? What are the evidence-based guidelines regarding the use of trimmed peripherally inserted central catheters among hospitalized neonatal patients? Key Message No evidence regarding the safety

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

13. Does Room Air Reduce Mortality Among Term Neonates Requiring Respiratory Support at Birth? Full Text available with Trip Pro

Wyckoff, M.H., Aziz, K., Escobedo, M.B. et al. Part 13: neonatal resuscitation: 2015 American Heart Association guidelines update for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation . 2015 ; 132 : S543–S560 Emergency provider knowledge of appropriate neonatal resuscitation measures is imperative to optimize care. Before 2000, resuscitation guidelines recommended 100% Fi o 2 for newborn respiratory support. x 6 Niermeyer, S., Kattwinkel, J., Van Reempts, P. et al (...) for initiating term newborn resuscitation: a systematic review with meta-analysis. Pediatrics . 2019 ; 143 : e20181825 Despite the mortality benefit of room air resuscitation in term neonates, there have been no new studies published since 2007. Because current neonatal resuscitation techniques include continuous oxygen saturation monitoring and oxygen titration to achieve desired oxygen saturations, it is unclear whether studies in contemporary settings would yield similar findings. Evidence certainty

2019 Annals of Emergency Medicine Systematic Review Snapshots

14. Prenatal Management of Pregnancies at Risk of Fetal Neonatal Alloimmune Thrombocytopenia (FNAIT)

as a potential predictor of alloimmune thrombocytopenia in the newborn . Haematologica 2008 ; 93 : 870 – 7 . 20 Ghevaert, C , Campbell, K , Walton, J , Smith, GA , Allen, D , Williamson, LM , et al. Management and outcome of 200 cases of fetomaternal alloimmune thrombocytopenia . Transfusion 2007 ; 47 : 901 – 10 . 21 Durand‐Zaleski, I , Schlegel, N , Blum‐Boisgard, C , Uzan, S , Dreyfus, M , Kaplan, C ; Immune Thrombocytopenia Working Group . Screening primiparous women and newborns for fetal/neonatal (...) Prenatal Management of Pregnancies at Risk of Fetal Neonatal Alloimmune Thrombocytopenia (FNAIT) Prenatal Management of Pregnancies at Risk of Fetal Neonatal Alloimmune Thrombocytopenia (FNAIT) - Regan - - BJOG: An International Journal of Obstetrics & Gynaecology - Wiley Online Library By continuing to browse this site, you agree to its use of cookies as described in our . Search within Search term Search term RCOG Scientific Impact Paper Free Access Prenatal Management of Pregnancies

2019 Royal College of Obstetricians and Gynaecologists

15. COVID-19: Operational framework for maternity and neonatal services

COVID-19: Operational framework for maternity and neonatal services Maternity and Neonatal Operational F ramework Queensland Health Clinical Excellence Queensland COVID-19: Operational framework for maternity and neonatal services Queensland Clinical Guideline: COVID-19: Operational Framework Refer to online version, destroy printed copies after use Page 2 of 12 Document title: Publication date: Document number: COVID-19: Operational framework for maternity and neonatal services March 26 2020 (...) MN20.63-2-V1-R2 5 Document supplement: The document supplement is integral to and should be read in conjunction Amendments: Amendment date: Replaces document: Author: Audience: Review date: Endorsed by: Contact: with this guideline. Full version history is supplied in the document supplement. New document New document Queensland Clinical Guidelines Health professionals in Queensland public and private maternity and neonatal services March 202 5 Queensland Clinical Guidelines Steering Committee

2020 Queensland Health

16. Neurosonography in Neonates and Infants

2017; 90:250–255. 22. Gupta P, Sodhi KS, Saxena AK, Khandelwal N, Singhi P. Neonatal cranial sonography: a concise review for clinicians. J Pediatr Neu- rosci 2016; 11:7–13. 23. Frankel DA, Fessell DP, Wolfson WP. High resolution sono- graphic determination of the normal dimensions of the intracranial extraaxial compartment in the newborn infant. J Ultrasound Med 1998; 17:411–415. 24. Gerner GJ, Burton VJ, Poretti A, et al. Transfontanellar duplex brain ultrasonography resistive indices (...) Neurosonography in Neonates and Infants PRACTICEPARAMETERS AIUM Practice Parameter for the Performance of Neurosonography in Neonates and Infants Introduction T he American Institute of Ultrasound in Medicine (AIUM) is a multidisciplinary association dedicated to advancing the safe and effective use of ultrasound in medicine through professional and public education, research, development of clinical practice parameters, and accreditation of practices performing ultrasound examinations

2020 American Institute of Ultrasound in Medicine

17. Neonatal jaundice

Neonatal jaundice Neonatal jaundice - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Neonatal jaundice Last reviewed: February 2019 Last updated: January 2019 Summary Usually noted clinically when serum bilirubin is >85.5 micromol/L (5 mg/dL). Occurs in 50% to 70% of term neonates. Most cases physiological. Jaundice in the first 24 hours of life is considered pathological. Treatment for severe hyperbilirubinaemia (...) includes phototherapy and/or exchange transfusion. The major complication of unconjugated hyperbilirubinaemia is kernicterus. Definition Neonatal jaundice is the yellowing discoloration of the skin and sclera of a neonate, which is caused by increased levels of bilirubin in the blood. A neonate refers to an infant in the first 28 days of life. This topic focuses on recognising and managing early neonatal jaundice, which is most commonly caused by unconjugated hyperbilirubinaemia. While prolonged

2018 BMJ Best Practice

18. WITHDRAWN: Techniques to ascertain correct endotracheal tube placement in neonates. Full Text available with Trip Pro

emerged (e.g. respiratory function monitor), which have been claimed to be superior in the assessment of tube placement.To assess various techniques for the identification of correct ETT placement after oral or nasal intubation in newborn infants in either the delivery room or neonatal intensive care unit compared with chest radiography.We searched the Cochrane Central Register of Controlled Trials (CENTRAL,The Cochrane Library 2012, Issue 4), MEDLINE (January 1996 to June 2014), EMBASE (January 1980 (...) WITHDRAWN: Techniques to ascertain correct endotracheal tube placement in neonates. The success rate of correct endotracheal tube (ETT) placement for junior medical staff is less than 50% and accidental oesophageal intubation is common. Rapid confirmation of correct tube placement is important because tube malposition is associated with serious adverse outcomes including hypoxaemia, death, pneumothorax and right upper lobe collapse.ETT position can be confirmed using chest radiography

2018 Cochrane

19. Prophylactic vitamin K for the prevention of vitamin K deficiency bleeding in preterm neonates. Full Text available with Trip Pro

Prophylactic vitamin K for the prevention of vitamin K deficiency bleeding in preterm neonates. Vitamin K is necessary for the synthesis of coagulation factors. Term infants, especially those who are exclusively breast fed, are deficient in vitamin K and consequently may have vitamin K deficiency bleeding (VKDB). Preterm infants are potentially at greater risk for VKDB because of delayed feeding and subsequent delay in the colonization of their gastrointestinal system with vitamin K producing (...) microflora, as well as immature hepatic and hemostatic function.  OBJECTIVES: To determine the effect of vitamin K prophylaxis in the prevention of vitamin K deficiency bleeding (VKDB) in preterm infants.We used the standard search strategy of Cochrane Neonatal to search the Cochrane Central Register of Controlled Trials (CENTRAL 2016, Issue 11), MEDLINE via PubMed (1966 to 5 December 2016), Embase (1980 to 5 December 2016), and CINAHL (1982 to 5 December 2016). We also searched clinical trials databases

2018 Cochrane

20. Prostaglandin E1 for maintaining ductal patency in neonates with ductal-dependent cardiac lesions. Full Text available with Trip Pro

Prostaglandin E1 for maintaining ductal patency in neonates with ductal-dependent cardiac lesions. Prostaglandin E1 (PGE1) is used to keep the ductus arteriosus patent and can be life-saving in neonates with ductal-dependent cardiac lesions. PGE1 is used to promote mixing of pulmonary and systemic blood flow or improve pulmonary or systemic circulations, prior to balloon atrial septostomy or surgery. PGE1 therapy may cause several short-term and long-term adverse effects. The efficacy (...) and safety of PGE1 in neonates with ductal-dependent cardiac lesions has not been systematically reviewed.To determine the efficacy and safety of both short-term (< 120 hours) and long-term (≥120 hours) PGE1 therapy in maintaining patency of the ductus arteriosus and decreasing mortality in ductal-dependent cardiac lesions.We searched the literature in October 2017, using the search strategy recommended by Cochrane Neonatal. We searched electronic databases (CENTRAL (in the Cochrane Library), MEDLINE

2018 Cochrane

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