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121. The association between influenza vaccination and the risk of SARS-CoV-2 infection, severe illness, and death: a systematic review of the literature. Full Text available with Trip Pro

The association between influenza vaccination and the risk of SARS-CoV-2 infection, severe illness, and death: a systematic review of the literature. The association between influenza vaccination and the risk of SARS-CoV-2 infection, severe illness, and death: a systematic review of the literature. | medRxiv Search for this keyword The association between influenza vaccination and the risk of SARS-CoV-2 infection, severe illness, and death: a systematic review of the literature. Marco Del (...) Netherlands Institute for Health Services Research (NIVEL), Utrecht, the Netherlands; For correspondence: Saverio Caini 4 Institute for Cancer Research, Prevention and Clinical Network (ISPRO) For correspondence: Abstract We reviewed the association between seasonal influenza vaccination and the risk of SARS-CoV-2 infection or complicated illness or poor outcome (e.g. severe disease, need for hospitalization or ventilatory support, or death) among COVID-19 patients. None of the studies that were reviewed

2020 Cold Spring Harbor Laboratory

122. A systematic review of studies describing the influence of informal social support on psychological wellbeing in people bereaved by sudden or violent causes of death Full Text available with Trip Pro

A systematic review of studies describing the influence of informal social support on psychological wellbeing in people bereaved by sudden or violent causes of death A systematic review of studies describing the influence of informal social support on psychological wellbeing in people bereaved by sudden or violent causes of death | Research Square Browse Tools & Services Your Cart This preprint is under consideration at BMC Psychiatry . A preprint is a preliminary version of a manuscript (...) that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice. Research article A systematic review of studies describing the influence of informal social support on psychological wellbeing in people bereaved by sudden or violent causes of death Hannah

2020 Research Square

123. A systematic review of studies describing the influence of informal social support on psychological wellbeing in people bereaved by sudden or violent causes of death Full Text available with Trip Pro

A systematic review of studies describing the influence of informal social support on psychological wellbeing in people bereaved by sudden or violent causes of death A systematic review of studies describing the influence of informal social support on psychological wellbeing in people bereaved by sudden or violent causes of death | Research Square Browse Tools & Services Your Cart This preprint is under consideration at BMC Psychiatry . A preprint is a preliminary version of a manuscript (...) that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice. Research article A systematic review of studies describing the influence of informal social support on psychological wellbeing in people bereaved by sudden or violent causes of death Hannah

2020 Research Square

124. Risk factors associated with fatal outcomes of novel coronavirus infection pneumonia (COVID-19): A systematic review and meta-analysis Full Text available with Trip Pro

for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China. Corresponding Author DOI: License: This work is licensed under a CC BY 4.0 License. Abstract Background: The COVID-19 infection has caused 111652 deaths worldwide as of 13 April 2020. Risk factors for fatal outcomes (...) of COVID-19 have varied across studies due to limited samples and have lacked effective qualitative and quantitative measurements. We performed a meta-analysis to evaluate risk factors for fatal outcomes of COVID-19. Methods: Data on demographic, clinic, laboratory findings and complications were extracted. Quantitative and qualitative synthesis was conducted for weighted-mean-difference (WMD) and odds-ratio (OR) . Results: A total of 30 studies involving 5741 survivors and 1670 deaths were included

2020 Research Square

125. Acute kidney injury is associated with severe and fatal outcomes in patients with Coronavirus disease 2019 (COVID-19) infection: a systematic review and meta-analysis of observational studies Full Text available with Trip Pro

<0.001 and WMD for mortality=-22.74 mL/min/1.73 m2, 95% CI=-27.18 to -18.31, P<0.001) were associated with a significant increase in the severity and mortality of COVID-19 infection. Acute kidney injury, as assessed by kidney biomarkers (serum creatinine, BUN and eGFR), was associated with severe outcome and death from COVID-19 infection. Competing Interest Statement The authors have declared no competing interest. Funding Statement This research did not receive any specific grant from funding (...) Acute kidney injury is associated with severe and fatal outcomes in patients with Coronavirus disease 2019 (COVID-19) infection: a systematic review and meta-analysis of observational studies Acute kidney injury is associated with severe and fatal outcomes in patients with Coronavirus disease 2019 (COVID-19) infection: a systematic review and meta-analysis of observational studies | medRxiv Search for this keyword Acute kidney injury is associated with severe and fatal outcomes in patients

2020 Cold Spring Harbor Laboratory

126. Quantification of the association between predisposing health conditions, demographic, and behavioural factors with hospitalisation, intensive care unit admission, and death from COVID-19: a systematic review and meta-analysis Full Text available with Trip Pro

. Results 75 studies were included into qualitative and 74 into quantitative synthesis, with study populations ranging from 19 - 44,672 COVID-19 cases. The risk of dying from COVID-19 was significantly associated with cerebrovascular [pooled RR 2.7 (95% CI 1.7-4.1)] and cardiovascular [RR 3.2 (CI 2.3-4.5)] diseases, hypertension [RR 2.6 (CI 2.0-3.4)], and renal disease [RR 2.5 (CI 1.8-3.4)]. Health care workers had lower risk for death and severe outcomes of disease (RR 0.1 (CI 0.1-0.3). Our meta (...) Quantification of the association between predisposing health conditions, demographic, and behavioural factors with hospitalisation, intensive care unit admission, and death from COVID-19: a systematic review and meta-analysis Quantification of the association between predisposing health conditions, demographic, and behavioural factors with hospitalisation, intensive care unit admission, and death from COVID-19: a systematic review and meta-analysis | medRxiv Search for this keyword

2020 Cold Spring Harbor Laboratory

127. Case fatality rate in COVID-19: a systematic review and meta-analysis Full Text available with Trip Pro

Case fatality rate in COVID-19: a systematic review and meta-analysis Case fatality rate in COVID-19: a systematic review and meta-analysis | medRxiv Search for this keyword Case fatality rate in COVID-19: a systematic review and meta-analysis Chanaka Kahathuduwa , Chathurika Dhanasekara , Shao-Hua Chin doi: https://doi.org/10.1101/2020.04.01.20050476 Chanaka Kahathuduwa 1 Department of Laboratory Science and Primary Care, Texas Tech University Health Sciences Center , Lubbock, Texas, USA 2 (...) Department of Psychiatry, Texas Tech University Health Sciences Center , Lubbock, Texas, USA 3 Department of Physiology, University of Peradeniy a, Peradeniya, Sri Lanka For correspondence: Chathurika Dhanasekara 4 Department of Surgery, Texas Tech University Health Sciences Center , Lubbock, Texas, USA Shao-Hua Chin 5 Department of Medical Science, Protech Pharmaservices Corporation , Taipei City, Taiwan Abstract Background Estimating the prevalence of severe or critical illness and case fatality

2020 Cold Spring Harbor Laboratory

128. Effects of pre-existing morbidities on occurrence of death among COVID-19 disease patients: A systematic review and meta-analysis Full Text available with Trip Pro

categories. These findings could potentially help healthcare providers to sort out the most endangered COVID-19 patients by comorbidities, take precautionary measures during hospitalization, assess susceptibility to death, and prioritize their treatment, which could potentially reduce the number of fatalities in COVID-19. Competing Interest Statement The authors have declared no competing interest. Funding Statement The authors have received no specific funds for this study. Author Declarations All (...) Effects of pre-existing morbidities on occurrence of death among COVID-19 disease patients: A systematic review and meta-analysis Effects of underlying morbidities on the occurrence of deaths in COVID-19 patients: A systematic review and meta-analysis | medRxiv Search for this keyword Effects of underlying morbidities on the occurrence of deaths in COVID-19 patients: A systematic review and meta-analysis Md. Mostaured Ali Khan , Md. Nuruzzaman Khan , Md. Golam Mustagir , Juwel Rana , Md. Saiful

2020 Cold Spring Harbor Laboratory

129. The impact of vital signs on the death of patients with new coronavirus pneumonia: A systematic review and meta-analysis Full Text available with Trip Pro

), SpO2: MD = -5.87, 95% CI (-9.17, -2.57), P = 0.0005]. However, comparing the body temperature of the death group and the survival group found that the body temperature was not statistically significant between the two groups [body temperature: MD = 0.21, 95% CI (-0.01, 0.43), P = 0.0661]. Conclusion: The increase in MAP, heart rate and respiratory rate, as well as the decrease in SBP, DBP and SpO2 are all independent risk factors for death in patients with COVID-19. These factors are simple (...) The impact of vital signs on the death of patients with new coronavirus pneumonia: A systematic review and meta-analysis The impact of vital signs on the death of patients with new coronavirus pneumonia: A systematic review and meta-analysis | medRxiv Search for this keyword The impact of vital signs on the death of patients with new coronavirus pneumonia: A systematic review and meta-analysis Meixia Du , Jie Zhao , Xiaochun Yin , Nadi Zhang , Guisen Zheng doi: https://doi.org/10.1101

2020 Cold Spring Harbor Laboratory

130. Association of hypertension, diabetes, stroke, cancer, kidney disease, and high-cholesterol with COVID-19 disease severity and fatality: a systematic review Full Text available with Trip Pro

Association of hypertension, diabetes, stroke, cancer, kidney disease, and high-cholesterol with COVID-19 disease severity and fatality: a systematic review Association of hypertension, diabetes, stroke, cancer, kidney disease, and high-cholesterol with COVID-19 disease severity and fatality: a systematic review | medRxiv Search for this keyword Association of hypertension, diabetes, stroke, cancer, kidney disease, and high-cholesterol with COVID-19 disease severity and fatality: a systematic (...) engine to screen a total of 59,000 articles in a few seconds. The search engine was built using a retrieval function that ranks a set of documents based on the query terms appearing in each document regardless of their proximity within the document. Filtering of the articles was then undertaken using keywords and questions, e.g. “Effects of diabetes on COVID/normal coronavirus/SARS-CoV-2/nCoV/COVID-19 disease severity, mortality?”. The search terms were repeated for all the comorbidities considered

2020 Cold Spring Harbor Laboratory

131. The effect of angiotensin converting enzyme inhibitors and angiotensin receptor blockers on death and severity of disease in patients with coronavirus disease 2019 (COVID-19): A meta-analysis Full Text available with Trip Pro

The effect of angiotensin converting enzyme inhibitors and angiotensin receptor blockers on death and severity of disease in patients with coronavirus disease 2019 (COVID-19): A meta-analysis The effect of angiotensin converting enzyme inhibitors and angiotensin receptor blockers on death and severity of disease in patients with coronavirus disease 2019 (COVID-19): A meta-analysis | medRxiv Search for this keyword The effect of angiotensin converting enzyme inhibitors and angiotensin receptor (...) blockers on death and severity of disease in patients with coronavirus disease 2019 (COVID-19): A meta-analysis S Ghosal , Jagat J Mukherjee , B Sinha , K Gangopadhyay doi: https://doi.org/10.1101/2020.04.23.20076661 S Ghosal 1 Consultant endocrinologist, Nightingale Hospital , Kolkata, India For correspondence: Jagat J Mukherjee 2 Consultant endocrinologist, Apollo Gleneagles Hospital , Kolkata, India B Sinha 3 Consultant endocrinologist, AMRI Hospitals , Kolkata, India K Gangopadhyay 4 Consultant

2020 Cold Spring Harbor Laboratory

132. Assessing the Age Specificity of Infection Fatality Rates for COVID-19: Meta-Analysis & Public Policy Implications Full Text available with Trip Pro

the criteria for acute respiratory illness.[186] Using the midpoint of that interval, we estimate that the total U.S. incidence of seasonal influenza during winter 2018-19 was about 63 million and hence that the infection fatality rate was about 0.05%. Supplementary Appendix P: Excess mortality In some locations, reported deaths may not fully capture all fatalities resulting from COVID-19 infections, especially when a large fraction of such deaths occurs outside of medical institutions. In the absence (...) . Moreover, the availability of live virus tests has varied significantly across locations and over time, and the deployment of such tests may differ markedly across demographic groups. Consequently, assessments of the case fatality rate (CFR), the ratio of deaths to reported cases, are fraught with pitfalls in gauging the severity of COVID-19. For example, early case reports from Wuhan noted a preponderance of older people among hospital admissions and a high CFR. Subsequent studies have documented

2020 National Bureau of Economic Research

133. Programmed cell death ligand 1 is a prognostic factor for glioblastoma: A systematic review and meta-analysis Full Text available with Trip Pro

Programmed cell death ligand 1 is a prognostic factor for glioblastoma: A systematic review and meta-analysis Inplasy Protocol 543 - INPLASY.COM International Platform of Registered Systematic Review and Meta-analysis Protocols Main Menu Share this: Copyright © 2021 INPLASY.COM Powered by INPLASY.COM

2020 INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols

134. Case-Fatality Risk Estimates for COVID-19 Calculated by Using a Lag Time for Fatality. Full Text available with Trip Pro

Case-Fatality Risk Estimates for COVID-19 Calculated by Using a Lag Time for Fatality. We estimated the case-fatality risk for coronavirus disease cases in China (3.5%); China, excluding Hubei Province (0.8%); 82 countries, territories, and areas (4.2%); and on a cruise ship (0.6%). Lower estimates might be closest to the true value, but a broad range of 0.25%-3.0% probably should be considered.

2020 Emerging Infectious Diseases

135. Infection is associated with one in five childhood deaths in England and Wales: analysis of national death registrations data, 2013-15. (Abstract)

%, 1368/6897) during 2003-05, equivalent to an infection-related mortality rate of 3.3/100 000 compared with 4.8/100 000 during the two periods (IRR 0.69, 95% CI 0.64 to 0.75), respectively. An underlying comorbidity was recorded in 55.0% (523/951) of death registrations during 2013-15 and increased with age. Where recorded, respiratory tract infection was the most commonly reported presentation (374/876, 42.7%) during 2013-15. Central nervous system infections accounted for only 4.8% (42/876 (...) ). Overall, 63.1% (378/599) of infection-related deaths were associated with a bacterial, 34.2% (205/599) with a viral and 2.5% (15/599) with a fungal infection.Beyond the neonatal period, all-cause and infection-related childhood mortality rates have declined by 26% and 31%, respectively, over the past decade. However, infection continues to contribute to one in five childhood deaths.© Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.

2020 Archives of Disease in Childhood

136. Recurrent sudden unexpected death in infancy: a case series of sibling deaths. Full Text available with Trip Pro

Recurrent sudden unexpected death in infancy: a case series of sibling deaths. To determine the rate of sudden unexpected death in infancy (SUDI) for infants born after a previous SUDI in the same family, and to establish the causes of death and the frequency of child protection concerns in families with recurrent SUDI.Observational study using clinical case records.The UK's Care of Next Infant (CONI) programme, which provides additional care to families who have experienced SUDI (...) with their subsequent children.Infants registered on CONI between January 2000 and December 2015.Cause of death, presence of modifiable risk factors for SUDI and child protection concerns.There were 6608 live-born infants registered in CONI with 29 deaths. 26 families had 2 deaths, and 3 families had 3 deaths. The SUDI rate for infants born after one SUDI is 3.93 (95% CI 2.7 to 5.8) per 1000 live births. Cause of death was unexplained for 19 first and 15 CONI deaths. Accidental asphyxia accounted for 2 first and 6

2020 Archives of Disease in Childhood

137. The short-term rate of non-fatal and fatal repetition of deliberate self-harm: A systematic review and meta-analysis of longitudinal studies. (Abstract)

The short-term rate of non-fatal and fatal repetition of deliberate self-harm: A systematic review and meta-analysis of longitudinal studies. Deliberate self-harm (DSH) is often recurrent, but the reported rate of short-term repetition of DSH has varied greatly. This systematic review and meta-analysis aim to synthesize findings through providing pooled rate estimates and to explore their differences by age, gender, and other factors.A comprehensive search of PubMed, Web of Science, EMBASE (...) , and PsycINFO was conducted to include longitudinal studies from 1999 to 2018. Random effects model was applied to pool rates of non-fatal and fatal repetition at 0.5, 1, 2, and 3 years intervals.Of 9201 potentially eligible articles 76 studies were included for this systematic review and meta-analysis. The pooled rates of non-fatal repetition were 15.01%, 17.03%, 20.82%, and 24.20% during the 0.5-year, 1-year, 2-year, and 3-year follow-up, respectively. The corresponding rates of fatal repetition were 0.77

2020 Journal of Affective Disorders

138. Differential Impact of Extended Criteria Donors After Brain Death or Circulatory Death in Adult Liver Transplantation. (Abstract)

Eurotransplant criteria. Our primary outcomes were graft and patient survival. A total of 798 grafts were used for LT, of which 93.1% were donation after brain death (DBD; 59.9% were also ECD) and 6.9% were DCD grafts (49.1% were also ECD). Among DBD graft recipients, donors having >33% liver steatosis or 3 ECD criteria resulted in poorer graft survival. Otherwise ECD graft recipients had similar graft and patient survival compared with non-ECD graft recipients. DCD graft recipients also had similar patient (...) Differential Impact of Extended Criteria Donors After Brain Death or Circulatory Death in Adult Liver Transplantation. Using grafts from extended criteria donors (ECDs) and donation after circulatory death (DCD) donors is a strategy to address organ shortage in liver transplantation (LT). We studied the characteristics and outcomes of ECD and DCD grafts. We retrospectively studied consecutive adults who underwent deceased donor LT between 2006 and 2019. ECD was defined using modified

2020 Liver Transplantation

139. Trends in disease incidence and survival and their effect on mortality in Scotland: nationwide cohort study of linked hospital admission and death records 2001-2016. Full Text available with Trip Pro

Trends in disease incidence and survival and their effect on mortality in Scotland: nationwide cohort study of linked hospital admission and death records 2001-2016. Identify causes and future trends underpinning Scottish mortality improvements and quantify the relative contributions of disease incidence and survival.Population-based study.Linked secondary care and mortality records across Scotland.1 967 130 individuals born between 1905 and 1965 and resident in Scotland from 2001 to 2016 (...) .Hospital admission rates and survival within 5 years postadmission for 28 diseases, stratified by sex and socioeconomic status.'Influenza and pneumonia', 'Symptoms and signs involving circulatory and respiratory systems' and 'Malignant neoplasm of respiratory and intrathoracic organs' were the hospital diagnosis groupings associated with most excess deaths, being both common and linked to high postadmission mortality. Using disease trends, we modelled a mean mortality HR of 0.737 (95% CI 0.730 to 0.745

2020 BMJ open

140. Impact on Nonfirearm Deaths of Firearm Laws Affecting Firearm Deaths: A Systematic Review and Meta-Analysis. (Abstract)

and Analysis. We extracted data from each study, including study timeframe, population, and statistical methods, as well as point estimates and inferential statistics for the effects of firearm policies on firearm deaths as well as either nonfirearm or overall deaths. We assessed quality at the estimate (study-policy-outcome) level by using prespecified criteria to evaluate the validity of inference and causal identification. For each estimate, we derived the mortality multiplier (i.e., the ratio (...) of the policy's effect on total homicides or suicides; expressed as a change in the number of deaths) as a proportion of its effect on firearm homicides or suicides. Finally, we performed a meta-analysis to estimate overall mortality multipliers for suicide and homicide that account for both within- and between-study heterogeneity.Main Results. We identified 16 eligible studies (study timeframes spanning 1977-2015). All examined state-level policies in the United States, with most estimating effects

2020 American Journal of Public Health

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