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1. Total versus partial knee replacement in patients with medial compartment knee osteoarthritis: the TOPKAT RCT (Full text)

Total versus partial knee replacement in patients with medial compartment knee osteoarthritis: the TOPKAT RCT Total versus partial knee replacement in patients with medial compartment knee osteoarthritis: the TOPKAT RCT Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try a website search above to find the information you (...) need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> 1)"> {{metadata.Title}} {{metadata.Headline}} Both total and partial knee replacement were effective and offered similar clinical outcomes at 5 years. {{author}} {{($index , , , , , , , , , , , , & . David J Beard 1, * , Loretta J Davies 1 , Jonathan A Cook 2 , Graeme MacLennan 2 , Andrew Price 1 , Seamus Kent 3 , Jemma Hudson 2 , Andrew Carr 1 , Jose Leal 3 , Helen Campbell 3 , Ray Fitzpatrick 3 , Nigel Arden 1 , David Murray 1

2020 NIHR HTA programme PubMed abstract

2. Joint replacement (primary): hip, knee and shoulder

Joint replacement (primary): hip, knee and shoulder Joint replacement (primary): hip, knee and shoulder NICE guideline Published: 4 June 2020 www.nice.org.uk/guidance/ng157 © NICE 2020. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Your responsibility Your responsibility The recommendations in this guideline represent the view of NICE, arrived at after careful consideration of the evidence available. When exercising (...) . Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Joint replacement (primary): hip, knee and shoulder (NG157) © NICE 2020. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 2 of 39Contents Contents Overview 5 Who is it for? 5 Recommendations 6 1.1 Shared decision

2020 National Institute for Health and Clinical Excellence - Clinical Guidelines

3. Exercise interventions and patient beliefs for people with hip, knee or hip and knee osteoarthritis: a mixed methods review. (Full text)

Exercise interventions and patient beliefs for people with hip, knee or hip and knee osteoarthritis: a mixed methods review. Chronic peripheral joint pain due to osteoarthritis (OA) is extremely prevalent and a major cause of physical dysfunction and psychosocial distress. Exercise is recommended to reduce joint pain and improve physical function, but the effect of exercise on psychosocial function (health beliefs, depression, anxiety and quality of life) in this population is unknown.To (...) of land- or water-based exercise programmes compared with a control group consisting of no treatment or non-exercise intervention (such as medication, patient education) that measured either pain or function and at least one psychosocial outcome (self-efficacy, depression, anxiety, quality of life). Participants had to be aged 45 years or older, with a clinical diagnosis of OA (as defined by the study) or self-reported chronic hip or knee (or both) pain (defined as more than six months' duration

2018 Cochrane PubMed abstract

4. The impact of the enhanced recovery pathway and other factors on outcomes and costs following hip and knee replacement: routine data study (Full text)

The impact of the enhanced recovery pathway and other factors on outcomes and costs following hip and knee replacement: routine data study The impact of the enhanced recovery pathway and other factors on outcomes and costs following hip and knee replacement: routine data study Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation (...) or try a website search above to find the information you need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> 1)"> {{metadata.Title}} {{metadata.Headline}} Improved outcomes after hip and knee replacement had begun before the implementation of the enhanced recovery pathway and successful implementation of this pathway depends on several aspects. {{author}} {{($index , , , , , , , , , , , , , , , & . Andrew Judge 1, 2, 3, 4, * , Andrew Carr 1 , Andrew Price 1 , Cesar Garriga 1, 4 , Cyrus

2020 NIHR HTA programme PubMed abstract

5. Platelet-rich plasma injections for knee osteoarthritis

Platelet-rich plasma injections for knee osteoarthritis Platelet-rich plasma injections for knee Platelet-rich plasma injections for knee osteoarthritis osteoarthritis Interventional procedures guidance Published: 23 January 2019 nice.org.uk/guidance/ipg637 Y Y our responsibility our responsibility This guidance represents the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, healthcare professionals are expected to take (...) #notice-of-rights). Page 1 of 41 1 Recommendations Recommendations 1.1 Current evidence on platelet-rich plasma injections for knee osteoarthritis raises no major safety concerns. However, the evidence on efficacy is limited in quality. Therefore, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. 1.2 Clinicians wishing to give platelet-rich plasma injections for knee osteoarthritis should: Inform the clinical governance leads

2019 National Institute for Health and Clinical Excellence - Interventional Procedures

6. Mosaicplasty for symptomatic articular cartilage defects of the knee

Mosaicplasty for symptomatic articular cartilage defects of the knee Mosaicplasty for symptomatic articular cartilage Mosaicplasty for symptomatic articular cartilage defects of the knee defects of the knee Interventional procedures guidance Published: 14 March 2018 nice.org.uk/guidance/ipg607 Y Y our responsibility our responsibility This guidance represents the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, healthcare (...) ://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 1 of 41 1 Recommendations Recommendations 1.1 Current evidence on the safety and efficacy of mosaicplasty for knee cartilage defects is adequate to support the use of this procedure provided that standard arrangements are in place for clinical governance, consent and audit. 1.2 The procedure should only be done by surgeons experienced in cartilage surgery and with specific training in mosaicplasty for knee cartilage defects. 1.3 Clinicians should

2018 National Institute for Health and Clinical Excellence - Interventional Procedures

7. Gamechanger? The Effect of Intra-articular Triamcinolone vs Saline on Knee Cartilage Volume and Pain in Patients with Knee Osteoarthritis ? A Randomized Clinical Trial

Gamechanger? The Effect of Intra-articular Triamcinolone vs Saline on Knee Cartilage Volume and Pain in Patients with Knee Osteoarthritis ? A Randomized Clinical Trial Gamechanger? The Effect of Intra-articular Triamcinolone vs Saline on Knee Cartilage Volume and Pain in Patients with Knee Osteoarthritis – A Randomized Clinical Trial – Clinical Correlations Search Gamechanger? The Effect of Intra-articular Triamcinolone vs Saline on Knee Cartilage Volume and Pain in Patients with Knee (...) that promote synovitis, as well as the up-regulation of [1]. Based on this proposed pathogenesis, the suppression of inflammatory mechanisms by intra-articular corticosteroids might theoretically reduce the progression of knee OA, with accompanying reduction in pain. This is an important area of study, as the pain associated with OA is the most prominent feature of the disease and is often undertreated. What did we know before? Though intra-articular corticosteroids have long been used to manage

2018 Clinical Correlations

8. Intra-articular hyaluronic acid injection for knee osteoarthritis: efficacy and adverse effects underestimated?

Intra-articular hyaluronic acid injection for knee osteoarthritis: efficacy and adverse effects underestimated? Prescrire IN ENGLISH - Spotlight ''Intra-articular hyaluronic acid injection for knee osteoarthritis: efficacy and adverse effects underestimated?'', 1 July 2020 {1} {1} {1} | | > > > Intra-articular hyaluronic acid injection for knee osteoarthritis: efficacy and adverse effects underestimated? Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |  (...)  |   |   |   |   |   |   |   |  Spotlight Intra-articular hyaluronic acid injection for knee osteoarthritis: efficacy and adverse effects underestimated? Queries and Comments Prescrire concluded in 2016 that the harm-benefit balance of hyaluronic acid by intra-articular injection seemed unfavourable. Several readers have since expressed their profound disagreement, citing the effects noted in their daily practice. How can

2020 Prescrire

9. The Arthroplasty Candidacy Help Engine tool to select candidates for hip and knee replacement surgery: development and economic modelling (Full text)

The Arthroplasty Candidacy Help Engine tool to select candidates for hip and knee replacement surgery: development and economic modelling The Arthroplasty Candidacy Help Engine tool to select candidates for hip and knee replacement surgery: development and economic modelling Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation (...) or try a website search above to find the information you need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> 1)"> {{metadata.Title}} {{metadata.Headline}} The Oxford hip and knee scores can be used to assess individuals' suitability for surgery, and this study showed that surgery nearly always costs less than £20,000 per QALY. {{author}} {{($index , , , , , , , , , , , , , , , , , , , , , , , , & . Andrew Price 1, * , James Smith 1 , Helen Dakin 2 , Sujin Kang 1 , Peter Eibich 2

2019 NIHR HTA programme PubMed abstract

10. Surgery for patellar tendinopathy (jumper's knee). (Abstract)

Surgery for patellar tendinopathy (jumper's knee). Patellar tendinopathy is an overuse condition that commonly affects athletes. Surgery is usually offered if medical and physical therapies fail to treat it effectively. There is variation in the type of surgery performed for the condition.To assess the benefits and harms of surgery for patellar tendinopathy in adults.We searched the following databases, to 17 July 2018: the Cochrane Central Register of Controlled Trials (CENTRAL) via (...) the Cochrane Library, OVID MEDLINE, OVID Embase, clinical trial registries (www.ClinicalTrials.gov) and the WHO trials portal (www.who.int/ictrp/en/).We included all randomised controlled trials (RCTs) that compared surgical techniques (open or arthroscopic) with non-operative treatment (including placebo surgery, exercise or other non-surgical modalities) in adults with patellar tendinopathy.Major outcomes assessed were knee pain, function, quality of life, participant global assessment of success

2019 Cochrane

11. Surgical interventions for symptomatic mild to moderate knee osteoarthritis. (Abstract)

Surgical interventions for symptomatic mild to moderate knee osteoarthritis. Osteoarthritis affecting the knee is common and represents a continuum of disease from early cartilage thinning to full-thickness cartilage loss, bony erosion, and deformity. Many studies do not stratify their results based on the severity of the disease at baseline or recruitment.To assess the benefits and harms of surgical intervention for the management of symptomatic mild to moderate knee osteoarthritis defined (...) as knee pain and radiographic evidence of non-end stage osteoarthritis (Kellgren-Lawrence grade 1, 2, 3 or equivalent on MRI/arthroscopy). Outcomes of interest included pain, function, radiographic progression, quality of life, short-term serious adverse events, re-operation rates and withdrawals due to adverse events.We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, and Embase up to May 2018. We also conducted searches of ClinicalTrials.gov and the WHO International

2019 Cochrane

12. WITHDRAWN: Peripheral nerve blocks for postoperative pain after major knee surgery. (Abstract)

WITHDRAWN: Peripheral nerve blocks for postoperative pain after major knee surgery. Major knee surgery is a common operative procedure to help people with end-stage knee disease or trauma to regain mobility and have improved quality of life. Poorly controlled pain immediately after surgery is still a key issue for this procedure. Peripheral nerve blocks are localized and site-specific analgesic options for major knee surgery. The increasing use of peripheral nerve blocks following major knee (...) surgery requires the synthesis of evidence to evaluate its effectiveness and safety, when compared with systemic, local infiltration, epidural and spinal analgesia.To examine the efficacy and safety of peripheral nerve blocks for postoperative pain control following major knee surgery using methods that permit comparison with systemic, local infiltration, epidural and spinal analgesia.We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (Issue 1, 2014), MEDLINE and EMBASE, from

2019 Cochrane

13. Active knee motion devices in the treatment of anterior cruciate ligament ruptures

Active knee motion devices in the treatment of anterior cruciate ligament ruptures 1 Translation of the key statement of the final report N16-01 Aktive Kniebewegungsschienen in der Behandlung von Rupturen des vorderen Kreuzbands (Version 1.0; Status: 16 March 2017). Please note: This document was translated by an external translator and is provided as a service by IQWiG to English-language readers. However, solely the German original text is absolutely authoritative and legally binding. Extract (...) IQWiG Reports – Commission No. N16-01 Active knee motion devices in the treatment of anterior cruciate ligament ruptures 1 Extract of final report N16-01 Version 1.0 Active knee motion devices for anterior cruciate ligament ruptures 16 March 2017 Institute for Quality and Efficiency in Health Care (IQWiG) - i - Publishing details Publisher: Institute for Quality and Efficiency in Health Care Topic: Active knee motion devices in the treatment of anterior cruciate ligament ruptures Commissioning

2019 Institute for Quality and Efficiency in Healthcare (IQWiG)

14. Motor-driven continuous passive motion (CPM) devices after interventions on the knee and shoulder joint

Motor-driven continuous passive motion (CPM) devices after interventions on the knee and shoulder joint 1 Translation of the key statement of the final report N16-03 Einsatz von motorbetriebenen Bewegungsschienen (CPM) nach Interventionen am Knie- oder am Schultergelenk (Version 1.1; Status: 23 July 2018). Please note: This document was translated by an external translator and is provided as a service by IQWiG to English-language readers. However, solely the German original text is absolutely (...) authoritative and legally binding. Extract IQWiG Reports – Commission No. N16-03 Motor-driven continuous passive motion (CPM) devices after interventions in the knee and shoulder joint 1 Extract of final report N16-03 Version 1.1 CPM devices after interventions in the knee and shoulder joint 23 July 2018 Institute for Quality and Efficiency in Health Care (IQWiG) - i - Publishing details Publisher: Institute for Quality and Efficiency in Health Care Topic: Motor-driven continuous passive motion (CPM

2019 Institute for Quality and Efficiency in Healthcare (IQWiG)

15. Autologous chondrocyte implantation using chondrosphere for treating symptomatic articular cartilage defects of the knee

Autologous chondrocyte implantation using chondrosphere for treating symptomatic articular cartilage defects of the knee Autologous chondrocyte implantation Autologous chondrocyte implantation using chondrosphere for treating using chondrosphere for treating symptomatic articular cartilage defects symptomatic articular cartilage defects of the knee of the knee T echnology appraisal guidance Published: 7 March 2018 nice.org.uk/guidance/ta508 © NICE 2018. All rights reserved. Subject to Notice (...) defects of the knee (TA508) © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 2 of 19Contents Contents 1 Recommendations 4 2 Information about chondrosphere 5 3 Committee discussion 6 Clinical management 6 Autologous chondrocyte implantation using chondrosphere 6 Comparators 7 Clinical evidence 8 Company's economic model 10 Assumptions in the economic model 12 Clinical effectiveness inputs and transition probabilities

2018 National Institute for Health and Clinical Excellence - Technology Appraisals

16. Paracetamol versus placebo for knee and hip osteoarthritis. (Full text)

Paracetamol versus placebo for knee and hip osteoarthritis. Paracetamol (acetaminophen) is vastly recommended as the first-line analgesic for osteoarthritis of the hip or knee. However, there has been controversy about this recommendation given recent studies have revealed small effects of paracetamol when compared with placebo. Nonetheless, past studies have not systematically reviewed and appraised the literature to investigate the effects of this drug on specific osteoarthritis sites (...) , that is, hip or knee, or on the dose used.To assess the benefits and harms of paracetamol compared with placebo in the treatment of osteoarthritis of the hip or knee.We searched the Cochrane Central Register of Controlled Trials, MEDLINE, Embase, AMED, CINAHL, Web of Science, LILACS, and International Pharmaceutical Abstracts to 3 October 2017, and ClinicalTrials.gov and the World Health Organization International Clinical Trials Registry Platform (ICTRP) portal on 20 October 2017.We included randomised

2019 Cochrane PubMed abstract

17. Effect of Biomechanical Footwear on Knee Pain in People With Knee Osteoarthritis: The BIOTOK Randomized Clinical Trial. (Abstract)

Effect of Biomechanical Footwear on Knee Pain in People With Knee Osteoarthritis: The BIOTOK Randomized Clinical Trial. Individually calibrated biomechanical footwear therapy may improve pain and physical function in people with symptomatic knee osteoarthritis, but the benefits of this therapy are unclear.To assess the effect of a biomechanical footwear therapy vs control footwear over 24 weeks of follow-up.Randomized clinical trial conducted at a Swiss university hospital. Participants (N (...)  = 220) with symptomatic, radiologically confirmed knee osteoarthritis were recruited between April 20, 2015, and January 10, 2017. The last participant visit occurred on August 15, 2017.Participants were randomized to biomechanical footwear involving shoes with individually adjustable external convex pods attached to the outsole (n = 111) or to control footwear (n = 109) that had visible outsole pods that were not adjustable and did not create a convex walking surface.The primary outcome was knee

2020 JAMA

18. A Randomized Controlled Trial Comparing a Medial Stabilized Total Knee Prosthesis to a Cruciate Retaining and Posterior Stabilized Design: A Report of the Clinical and Functional Outcomes Following Total Knee Replacement (Full text)

A Randomized Controlled Trial Comparing a Medial Stabilized Total Knee Prosthesis to a Cruciate Retaining and Posterior Stabilized Design: A Report of the Clinical and Functional Outcomes Following Total Knee Replacement A Randomized Controlled Trial Comparing a Medial Stabilized Total Knee Prosthesis to a Cruciate Retaining and Posterior Stabilized Design: A Report of the Clinical and Functional Outcomes Following Total Knee Replacement - PubMed This site needs JavaScript to work properly (...) at most: Send even when there aren't any new results Optional text in email: Save Cancel Create a file for external citation management software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation J Arthroplasty Actions . 2020 Jun;35(6):1583-1590.e2. doi: 10.1016/j.arth.2020.01.085. Epub 2020 Feb 7. A Randomized Controlled Trial Comparing a Medial Stabilized Total Knee Prosthesis to a Cruciate

2020 EvidenceUpdates PubMed abstract

19. Intra-Articular Hyaluronic Acid for Viscosupplementation in Osteoarthritis of the Knee: A Review of Clinical Effectiveness and Safety

Intra-Articular Hyaluronic Acid for Viscosupplementation in Osteoarthritis of the Knee: A Review of Clinical Effectiveness and Safety Intra-Articular Hyaluronic Acid for Viscosupplementation in Osteoarthritis of the Knee: A Review of Clinical Effectiveness and Safety | CADTH.ca Find the information you need Intra-Articular Hyaluronic Acid for Viscosupplementation in Osteoarthritis of the Knee: A Review of Clinical Effectiveness and Safety Intra-Articular Hyaluronic Acid for Viscosupplementation (...) in Osteoarthritis of the Knee: A Review of Clinical Effectiveness and Safety Last updated: June 24, 2019 Project Number: RC1136-000 Product Line: Research Type: Devices and Systems Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness and safety of intra-articular hyaluronic acid for patients with osteoarthritis of the knee joint? Key Message Evidence suggests that there may be differences in the efficacy of intraarticular hyaluronic acid for treatment

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

20. American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee

American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee 1 Arthritis Care & Research Vol. 0, No. 0, Month 2020, pp 1–14 DOI 10.1002/acr.24131 © 2020, American College of Rheumatology 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee Sharon L. Kolasinski, 1 Tuhina Neogi, 2 Marc C. Hochberg, 3 Carol Oatis, 4 Gordon Guyatt, 5 Joel Block, 6 Leigh (...) an evidence- based guideline for the comprehensive management of osteoarthritis (OA) as a collabora- tion between the American College of Rheumatology (ACR) and the Arthritis Foundation, updating the 2012 ACR recommenda- tions for the management of hand, hip, and knee OA. Methods. We identified clinically relevant population, intervention, comparator, outcomes questions and critical outcomes in OA. A Literature Review T eam performed a systematic literature review to summarize evidence supporting

2020 American College of Rheumatology

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