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1. A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version)

A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version) POSITION ARTICLE AND GUIDELINE Open Access A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version) Ying-Hui Jin 1 , Lin Cai 2 , Zhen-Shun Cheng 3 , Hong Cheng 4 , Tong Deng 1,5 , Yi-Pin Fan 6,7 , Cheng Fang 1 , Di Huang 1 , Lu-Qi Huang 6,7 , Qiao Huang 1 , Yong Han 2 ,BoHu 8 , Fen Hu 8 (...) 1,18* , Yong-Yan Wang 6,7* , Xing-Huan Wang 1,2* , for the Zhongnan Hospital of Wuhan University Novel Coronavirus Management and Research Team, Evidence-Based Medicine Chapter of China International Exchange and Promotive Association for Medical and Health Care (CPAM) Abstract In December 2019, a new type viral pneumonia cases occurred in Wuhan, Hubei Province; and then named “2019 novel coronavirus (2019-nCoV)” by the World Health Organization (WHO) on 12 January 2020. For it is a never been

2020 Covid-19 Ad hoc guidelines

2. The possibility of using Lopinave/Litonawe (LPV/r) as treatment for novel coronavirus (2019-nCov)pneumonia: a quick systematic review based on earlier coronavirus clinical studies Full Text available with Trip Pro

The possibility of using Lopinave/Litonawe (LPV/r) as treatment for novel coronavirus (2019-nCov)pneumonia: a quick systematic review based on earlier coronavirus clinical studies JCM | Free Full-Text | Potential Rapid Diagnostics, Vaccine and Therapeutics for 2019 Novel Coronavirus (2019-nCoV): A Systematic Review Next Article in Journal Next Article in Special Issue Previous Article in Journal Previous Article in Special Issue Information Initiatives Notice You can make submissions (...) for a specific problem on the support section of our website. Feedback Please let us know what you think of our products and services. Information Our dedicated information section provides allows you to learn more about MDPI. JSmol Viewer Open Access Review Potential Rapid Diagnostics, Vaccine and Therapeutics for 2019 Novel Coronavirus (2019-nCoV): A Systematic Review by 1,2,* , 1,2 , 1 , 1 , 1 , 1 , 3 , 1,2 , 1,2 , 1 , 1 , 1 , 1 , 1 , 4 , 1 , 1 and 1 1 Saw Swee Hock School of Public Health, National

2020 Covid-19 Ad hoc papers

3. COVID-19 (Novel Coronavirus)

COVID-19 (Novel Coronavirus) COVID-19 (Novel Coronavirus) You need to enable JavaScript to run this app. Person Subscribe for unlimited access to DynaMed content, CME/CE & MOC credit, and email alerts on content you follow. Subscribe Already subscribed? Language English Search Cancel Specialties KeyboardArrowDown 0 COVID-19 (Novel Coronavirus) List MoreVert AddCircleOutline Follow Share Share AddCircleOutline Follow Share Share General Information Description acute respiratory disease caused (...) by a novel coronavirus (SARS-CoV-2) first identified in December 2019 in Wuhan, Hubei Province, China and spreading worldwide ( ) PubMed 32123347 Nature microbiology Nat Microbiol 20200302 SARS-CoV-2 is a member of beta genus coronaviruses closely related to SARS-CoV ( ) common signs of COVID-19 include fever, cough, and shortness of breath ( ) there is no specific antiviral treatment for COVID-19, but supportive care may help to relieve symptoms and should include support of vital organ functions

2020 DynaMed Plus

4. Novel coronavirus (COVID-19) guidance for acute care

Novel coronavirus (COVID-19) guidance for acute care 1 | Pa g e Ministry of Health Novel Coronavirus (COVID-19) Guidance for Acute Care Version 2 – February 1 1, 2020 This guidance document provides basic information only. It is not intended to take the place of medical advice, communicable diseases surveillance protocols, diagnosis or treatment. What you need to know Acute care settings should: 1. Undertake active screening (asking questions) and passive screening (signage) of patients (...) to the Workplace Safety and Insurance Board (WSIB) by or on behalf of the worker with respect to an occupational illness, including an occupational infection, to the: • Ministry of Labour, • Joint Health and Safety Committee (or health and safety representative), and • trade union, if any. Occupationally-acquired infections and illnesses are reportable to the WSIB. Work restrictions for healthcare workers If novel coronavirus is suspected (i.e. symptoms AND relevant contact or travel to the impacted area

2020 CPG Infobase

5. Interim guidance: public health management of cases and contacts associated with novel coronavirus (COVID-19) in the community

for longer in the immunocompromised and pediatric populations. Two negative swabs, collected at least 24 hours apart, AND resolution of acute symptoms are required to rule out communicability and discontinue isolation DIAGNOSTIC TESTING PCR developed at BCCDC PHL Up to date lab testing guidelines can be found on the BCCDC Health Professionals page: http://www.bccdc.ca/health-professionals/clinical-resources/novel-coronavirus-(covid-19) SURVEILLANCE AND REPORTING Case definitions have been developed (...) Interim guidance: public health management of cases and contacts associated with novel coronavirus (COVID-19) in the community Interim Guidance: Public Health Management of cases and contacts associated with novel coronavirus (COVID-19) in the community March 10, 2020 CONTEXT The British Columbia Centre for Disease Control (BCCDC) has adapted the interim guidance from the Public Health Agency of Canada (PHAC) for Regional Health Authorities (RHA) for public health management of human illness

2020 CPG Infobase

6. Infection prevention and control for novel coronavirus (COVID-19): interim guidance for acute healthcare settings

Infection prevention and control for novel coronavirus (COVID-19): interim guidance for acute healthcare settings Infection prevention and control for coronavirus disease (COVID-19): Interim guidance for acute healthcare settings - Canada.ca Language selection Search Search Canada.ca Search Menu Main Menu You are here: Infection prevention and control for coronavirus disease (COVID-19): Interim guidance for acute healthcare settings Table of Contents Introduction The Public Health Agency (...) of Canada (the Agency) develops infection prevention and control (IPC) guidelines to provide evidence-based recommendations to complement provincial/territorial public health efforts in monitoring, preventing, and controlling healthcare-associated infections. This is the preliminary edition of IPC guidance on the coronavirus disease (COVID-19) that was first identified in Wuhan, China. The intended use of this document, infection prevention and control for coronavirus disease (COVID-19): interim

2020 CPG Infobase

7. Rational use of personal protective equipment for coronavirus disease (COVID-19)

Rational use of personal protective equipment for coronavirus disease (COVID-19) 1 Rational use of personal protective equipment (PPE) for coronavirus disease (COVID-19) Interim guidance 19 March 2020 Background This document summarizes WHO’s recommendations for the rational use of personal protective equipment (PPE) in health care and community settings, as well as during the handling of cargo; in this context, PPE includes gloves, medical masks, goggles or a face shield, and gowns, as well (...) production is limited, and the current demand for respirators and masks cannot be met, especially if widespread inappropriate use of PPE continues. Rational use of personal protective equipment for coronavirus disease (COVID-19): interim guidance -2- Recommendations for optimizing the availability of PPE In view of the global PPE shortage, the following strategies can facilitate optimal PPE availability (Figure 1). Figure 1. Strategies to optimize the availability of personal protective equipment (PPE) 1

2020 WHO Coronavirus disease (COVID-19) Pandemic

8. Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19)

respiratory illness epidemic in Wuhan, China [1]. The World Health Organization (WHO) termed this illness Coronavirus Disease 2019 (COVID-19). By the time this guideline panel was assembled, the COVID-19 had become a pandemic and had affected over 120,000 individuals in more than 80 countries, and resulted in more than 5000 deaths worldwide [2]. The WHO and the United States Center for Disease Control and Prevention (CDC) have issued preliminary guidance on infection control, screening and diagnosis (...) Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19) Intensive Care Medicine GUIDELINES Un-edited accepted proof* © European Society of Intensive Care Medicine and the Society of Critical Care Medicine 2020 1 Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19) Authors Waleed Alhazzani 1,2 , Morten Hylander Møller 3,4 , Yaseen M. Arabi 5 , Mark Loeb 1,2

2020 Covid-19 Ad hoc guidelines

9. Coronavirus (COVID-19) Infection in Pregnancy

not visit their GP practice or attend A&E in person. If it is an emergency they should phone 999 and tell the operator of possible COVID-19 exposure. Women returning from areas of the world which indicate a possible increased risk for coronavirus transmission (list for England, Wales and Northern Ireland; list for Scotland) or who have been in contact with a known case of COVID-19 should phone NHS 111 or, if in Scotland, NHS 24 (on 111) or their GP . Diagnostic swabs will be arranged if indicated (...) -19, and request advice on attendance. Pregnant women are advised not to attend maternity triage units or A&E unless in need of urgent obstetric or medical care. If women are concerned and require urgent medical advice, they are encouraged to call the maternity triage unit in the first instance. If attendance at the maternity unit or 9 2.4 Diagnosis of COVID-19 The process of COVID-19 diagnosis is changing rapidly. If diagnostic tests are advised, pregnant women should follow advice given, which

2020 Royal College of Obstetricians and Gynaecologists

10. Coronavirus (COVID-19): latest information and advice

in rotational teams of 7 clinicians, working in shifts, who will be on hand to support patients on arrival. This is in addition to medical staff who are already permanently in place at all UK airports and the advice issued to all UK airports for people travelling to and from China. The government has issued clinical guidance for the detection and diagnosis of novel coronavirus (COVID-19), and infection prevention and control. The Chief Medical Officer, Medical Director at PHE and Medical Director at NHSE/I (...) screening so people already exhibiting symptoms are not allowed to leave the country. Diagnosis and analysis Based on current evidence, novel coronavirus (COVID-19) presents with flu-like symptoms including a fever, a cough, or difficulty breathing. The current evidence is that most cases appear to be mild. Those who have died in Wuhan appear to have had pre-existing health conditions. The UK is now one of the first countries outside China to have a prototype specific laboratory test for this new

2020 Public Health England

11. Risk assessment guidelines for infectious diseases transmitted on aircraft (RAGIDA) - Middle East Respiratory Syndrome Coronavirus (MERS-CoV)

Risk assessment guidelines for infectious diseases transmitted on aircraft (RAGIDA) - Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Suggested citation: European Centre for Disease Prevention and Control. Risk assessment guidelines for infectious diseases transmitted on aircraft (RAGIDA). ECDC: Stockholm; 2020. © European Centre for Disease Prevention and Control, Stockholm, 2020 ECDC TECHNICAL REPORT Risk assessment guidelines for infectious diseases transmitted on aircraft (RAGIDA (...) ) Middle East Respiratory Syndrome Coronavirus (MERS-CoV) January 2020 Introduction The Middle East respiratory syndrome coronavirus (MERS-CoV) was first discovered in 2012 in a patient who died from severe respiratory disease [1]. Since then, and as of 16 January 2020, 2 521 cases have been reported worldwide, including 919 deaths (crude case fatality 36%). Most cases have been reported from the Arabian Peninsula (and around 84% specifically from Saudi Arabia), and all cases elsewhere had a travel

2020 European Centre for Disease Prevention and Control - Technical Guidance

12. Novel coronavirus (2019-nCoV): self-isolation for patients undergoing testing

for how patients should self-isolate while awaiting results of laboratory testing for SARS-CoV-2. Published 31 January 2020 Last updated 31 January 2020 — From: Documents HTML HTML HTML Details This guidance provides advice for individuals who are awaiting results from diagnostic testing for COVID-19 and do not require admission to hospital. COVID-19 was previously referred to as Wuhan novel coronavirus. There may be further information specific to each country in the United Kingdom, as this guidance (...) Novel coronavirus (2019-nCoV): self-isolation for patients undergoing testing COVID-19: self-isolation for patients undergoing testing - GOV.UK Tell us whether you accept cookies We use about how you use GOV.UK. We use this information to make the website work as well as possible and improve government services. Accept all cookies You’ve accepted all cookies. You can at any time. Hide Search The UK has left the EU Guidance COVID-19: self-isolation for patients undergoing testing Guidance

2020 Public Health England

13. What is the effectiveness and safety of antiviral or antibody treatments for coronavirus?

liver function in patients receiving ribavirin Summary Study and Patient Characteristics Characteristics (n) Controlled Trials (n=3) Cohort Studies (n=10) Retrospective Studies (n=7) Case Reports/Series (n=34) Diagnosis COVID-19 — — — 3 SARS 2 7 4 20 MERS 1 3 3 9 Other coronavirus — — — 2 Age of population (range) 22 to 57 15 to 70 22 to 79 4 months to 83 years Sample size [median (range)] 43 (16 to 190) 169 (72 to 1934) 63 (14 to 306) 8 (1 to 323) Publication Year (range) 2004 to 2019 2003 to 2019 (...) What is the effectiveness and safety of antiviral or antibody treatments for coronavirus? What is the effectiveness and safety of antiviral or antibody treatments for coronavirus? - CEBM CEBM The Centre for Evidence-Based Medicine develops, promotes and disseminates better evidence for healthcare. Navigate this website What is the effectiveness and safety of antiviral or antibody treatments for coronavirus? March 26, 2020 Patricia Rios, Amruta Radhakrishnan, Jesmin Antony, Sonia M. Thomas

2020 Oxford COVID-19 Evidence Service

14. Coronavirus Disease 2019 (COVID-19): A Systematic Review of Imaging Findings in 919 Patients Full Text available with Trip Pro

onset [ , ]. In the intermediate to advanced stages of the disease, chest radiographs may show progression of features of acute respiratory distress syndrome (ARDS) ( ). Furthermore, CT findings have proven to be diagnostic in a number of cases with an initial false-negative reverse transcription polymerase chain reaction (RTPCR) screening test [ , ]. An assessment of 41 patients with a laboratory-confirmed COVID-19 diagnosis revealed abnormal chest CT findings in all cases [ ]. Subsequently (...) , multiple case series were published, aiming to define the CT features of COVID-19 pneumonia. Fig. 1A —79-year-old woman who presented with chest pain, cough, and fever for 3 days. Coronavirus disease (COVID-19) had recently been diagnosed in two of her household members. Patient developed acute respiratory distress syndrome within subsequent few days and died 11 days after admission. (Courtesy of Song F, Shanghai Public Health Clinical Center, Shanghai, China) A, CT image ( A ) and chest radiograph ( B

2020 Covid-19 Ad hoc papers

15. Joint RCOG, BSGE and BGCS guidance for the management of abnormal uterine bleeding in the evolving Coronavirus (COVID-19) pandemic

. o Women in whom a cancer is diagnosed should be referred to a gynaecological oncology MDT for further management. o Women in whom a cancer is diagnosed should be sensitively informed of the diagnosis. Ideally, this should be in a face to face consultation. However, the extent of the pandemic and patient factors may make it necessary to do so in a non-face-to-face consultation. Post coital bleeding ? Women with PCB should initially be managed by remote communication to: o Reassure them (...) Joint RCOG, BSGE and BGCS guidance for the management of abnormal uterine bleeding in the evolving Coronavirus (COVID-19) pandemic Joint RCOG, BSGE and BGCS guidance for the management of abnormal uterine bleeding in the evolving Coronavirus (COVID-19) pandemic This consensus statement provides a framework for the management of women with abnormal uterine bleeding (heavy menstrual bleeding (HMB), inter-menstrual (IMB), postmenopausal bleeding (PMB) or post coital bleeding (PCB)) during

2020 Royal College of Obstetricians and Gynaecologists

16. Guidance for maternal medicine in the evolving coronavirus (COVID-19) pandemic

to the usual principles, considering all differential diagnoses. The use of RCP Acute Care T oolkit 15 is advised for both. 23 27 References 1. COVID-19: guidance on social distancing and for vulnerable people 2020 [Available from: https://www.gov. uk/government/publications/covid-19-guidance-on-social-distancing-and-for-vulnerable-people accessed 17 March 2020. 2. Major new measures to protect people at highest risk from coronavirus 2020 [updated 21 March. Available from: https://www.gov.uk/government (...) /news/major-new-measures-to-protect-people-at-highest-risk-from- coronavirus. 3. Hypertension in pregnancy: diagnosis and management. In: National Institute for Health and Care Excellence, ed., 2019. 4. Preterm labour and birth. In: National Institute for Health and Care Excellence, ed., 2019. 5. National Institute for Health and Care Excellence. Diabetes in pregnancy: management from preconception to the postnatal period, 2015. 6. Covid-19 Information Governance advice for health and care

2020 Royal College of Obstetricians and Gynaecologists

17. Novel coronavirus (COVID-19) Guidance for Primary Care Management of patients presenting to primary care

Novel coronavirus (COVID-19) Guidance for Primary Care Management of patients presenting to primary care Health Protection Scotland This document is uncontrolled when printed. Before use check the HPS COVID-19 page to verify this is the current version Novel coronavirus (COVID-19) Guidance for Primary Care Management of patients presenting to primary care Version 10.4 Publication date 27 March 2020 Health Protection Scotland 1 Version History Version Date Summary of changes V1.0 23/01/20 First (...) publication V2.0 24/01/20 Added: - Algorithm for suspect case of WN-Cov in primary care V3.0 28/01/20 Added: - Section 4 – environmental cleaning following possible case in primary care - Appendix 3 – putting on and removing PPE in primary care Amended: - Appendix 1 updated to include NHS24 V4.0 31/01/20 Amended clinical and epidemiological case definition and updated appendix 1 (algorithm for management of suspected case of novel coronavirus in Primary Care), Reference to Wuhan Coronavirus (WN-Cov

2020 Covid-19 Ad hoc guidelines

18. Guidance for antenatal screening and ultrasound in pregnancy in the evolving coronavirus (COVID-19) pandemic

Guidance for antenatal screening and ultrasound in pregnancy in the evolving coronavirus (COVID-19) pandemic 1 Information for healthcare professionals Version 1: Published Monday 23 March 2020 Guidance for antenatal screening and ultrasound in pregnancy in the evolving coronavirus (COVID-19) pandemic2 Authors Matthew Jolly, NHS England & NHS Improvement Myles T aylor, BMFMS Jane Fisher, ARC Nadia Permalloo, PHE Annette McHugh, PHE Christoph Lees, Imperial College/ISUOG Pranav Pandya, UCLH/PHE (...) . Assessment of women presenting for screening and/or scanning All women should be asked to attend alone if possible or with a maximum of one partner/visitor. 2.1 Screening for possible coronavirus infection All women should be initially screened before entering the department to see if they have symptoms that are suggestive of COVID-19, or if they meet current ‘stay at home’ guidance. If a woman currently meets ‘stay at home’ guidance the appointment should be rebooked after the isolation period ends

2020 Royal College of Obstetricians and Gynaecologists

19. Guidance for fetal medicine units (FMUs) in the evolving coronavirus (COVID-19) pandemic

Guidance for fetal medicine units (FMUs) in the evolving coronavirus (COVID-19) pandemic 1 Information for healthcare professionals Version 1: Published Monday 23 March 2020 Guidance for fetal medicine units (FMUs) in the evolving coronavirus (COVID-19) pandemic2 Authors Matthew Jolly, NHS England & NHS Improvement Myles T aylor, BMFMS Jane Fisher, ARC Nadia Permalloo, PHE Annette McHugh, PHE Christoph Lees, Imperial College/ISUOG Pranav Pandya, UCLH/PHE Eddie Morris, RCOG Jo Mountfield , RCOG (...) Tim Draycott, RCOG Pat O’Brien, RCOG Ranee Thakar, RCOG Sue Ward, RCOG Jennifer Jardine, RCOG Sophie Relph, RCOG Gemma Goodyear, RCOG3 1. Introduction This guidance is for fetal medicine services to use in the evolving coronavirus pandemic. 2. Ensuring that fetal medicine units are used appropriately We recommend the following: • All referrals to be discussed with a FMU consultant • Patients should be asked to attend alone if possible or with a maximum of one partner/visitor • Patients referred

2020 Royal College of Obstetricians and Gynaecologists

20. Guidance for antenatal and postnatal services in the evolving coronavirus (COVID-19) pandemic

Guidance for antenatal and postnatal services in the evolving coronavirus (COVID-19) pandemic 1 Information for healthcare professionals Version 1: Published Monday 30 March 2020 Guidance for antenatal and postnatal services in the evolving coronavirus (COVID-19) pandemic2 1. Introduction This guidance is for antenatal and postnatal services to support them during the evolving coronavirus pandemic. This document intends to outline which elements of routine antenatal and postnatal care (...) are essential and which could be modified, given national recommendations for social distancing of pregnant women. 2. Providing a safe and responsive antenatal and postnatal care service General guidance for services is provided in the RCOG’s coronavirus guideline. 2.1 Provision of advice for women about antenatal and postnatal care Maternity services should provide clear signposting for pregnant and postnatal women about changes to antenatal and postnatal services on their Trust or Health Board websites

2020 Royal College of Obstetricians and Gynaecologists

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