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101. Unusual Cancers of Childhood Treatment (PDQ®): Health Professional Version

guidelines or recommendations for making health care decisions. This summary is reviewed regularly and updated as necessary by the PDQ Pediatric Treatment Editorial Board, which is editorially independent of the National Cancer Institute (NCI). The summary reflects an independent review of the literature and does not represent a policy statement of NCI or the National Institutes of Health (NIH). General Information About Unusual Cancers of Childhood Introduction Cancer in children and adolescents is rare (...) specialists, pediatric nurse specialists, social workers, and others to ensure that children receive treatment, supportive care, and rehabilitation that will achieve optimal survival and quality of life. (Refer to the PDQ summaries for specific information about supportive care for children and adolescents with cancer.) Guidelines for pediatric cancer centers and their role in the treatment of pediatric patients with cancer have been outlined by the American Academy of Pediatrics.[ ] At these pediatric

2018 PDQ - NCI's Comprehensive Cancer Database

102. Sciatica (lumbar radiculopathy)

healthcare. How up-to-date is this topic? How up-to-date is this topic? Changes Changes March 2018 — minor update. New symptoms added to to bring topic in line with current evidence. January to March 2017 — reviewed and updated. A literature search was conducted in January 2017 to identify evidence-based guidelines, UK policy, systematic reviews, and key randomized controlled trials published since the last revision of this topic. The topic has undergone restructuring. No major changes (...) to the recommendations have been made. Previous changes Previous changes April 2015 — minor update. Update to the text to reflect a new law on drugs and impaired driving. March 2015 — reviewed. A literature search was conducted in January 2015 to identify evidence-based guidelines, UK policy, systematic reviews, and key randomized controlled trials published since the last revision of this topic. The topic has undergone minor restructuring and the prescribing information section has been expanded. No major changes

2018 NICE Clinical Knowledge Summaries

103. Febrile seizure

audience for this CKS topic is healthcare professionals working within the NHS in the UK, and providing first contact or primary healthcare. How up-to-date is this topic? How up-to-date is this topic? Changes Changes October to November 2018 — reviewed. A literature search was conducted in October 2018 to identify evidence-based guidelines, UK policy, systematic reviews, and key randomized controlled trials published since the last revision of this topic. The topic has undergone minor restructuring (...) , and new nodes on Assessment and Differential diagnosis have been added. Recommendations in the Management section have been updated in line with current literature. Previous changes Previous changes October 2013 — revised. A literature search was conducted in July 2013 to identify evidence-based guidelines, UK policy, systematic reviews, and key randomized controlled trials published since the last revision of the topic. Minor changes have been made to the National Institute for Health and Care

2018 NICE Clinical Knowledge Summaries

104. Neuraceq - florbetaben (18F)

. The Scientific Advice pertained to clinical aspects of the dossier. Neuraceq EMA/5028/2014 Page 6/114 Licensing status The product was not licensed in any country at the time of submission of the application. 1.2. Manufacturers Manufacturers responsible for batch release BV Cyclotron VU De Boelelaan 1081 1081 Amsterdam Netherlands CIS BIO INTERNATIONAL - PARIS 14 rue de la Grange aux Belles 75010 PARIS France IBA MOLECULAR ITALY c/o Ospedale San Gerardo dei Tintori VIA PERGOLESI,33 20052 Monza Italy Alliance (...) during the synthesis. The characterisation of the active substance and its impurities are in accordance with the EU guideline on chemistry of new active substances. Potential and actual impurities were well discussed with regards to their origin and characterised. Adequate specifications and control methods for intermediate products, starting materials and reagents have been presented. Adequate specification of the IFP (Integrated Fluidic Processor) including inspection of absence of defects

2014 European Medicines Agency - EPARs

105. Using a bath or pool during first stage labour: A decision aid for women having a vaginal birth

a woman is immersed in water. Sometimes a woman’s care provider may suggest she gets out of the water while the monitoring is performed. You can ask your care provider if your planned place of birth has monitoring machines that are designed to be used during water immersion. If you are using water immersion, your hospital or birth centre may have guidelines about using a bath or pool during labour (e.g. about the temperature of the water and whether it is suitable to use the pool if your waters have (...) broken before 37 weeks). You can ask your care provider for more information about guidelines for water immersion at your planned place of birth . Option 1 Option 2 What happens if I choose not to use a bath or pool? What happens if I choose a bath or pool? 7Some hospitals or birth centres do not have the facilities or staff training available for using a bath or pool during labour. Your might like to ask your care provider about the facilities available to you at your planned place of birth. In some

2015 EUnetHTA

106. Monitoring your baby during labour: A decision aid for women having a vaginal birth

with a cardiotocograph for 20 to 30 minutes when they first arrived at their chosen place of birth in labour. Some hospitals still suggest that all women are monitored when they first arrive while others do not. Studies have shown that there is no evidence of benefit for this practice for low risk women, therefore it is no longer recommended. [9] Photo courtesy of Herston Multimedia Unit 6You can choose when and how your baby is monitored during labour. Hospitals or birth centres usually have guidelines for care (...) providers about when intermittent and continuous monitoring is used. Different care providers might also vary in their preferences for monitoring in different circumstances [7]. You might like to ask your care provider about these guidelines at your chosen place of birth. In normal labour when no complications are expected, intermittent monitoring of the baby’s heart is usually offered. Low risk women may not always be able to choose to have continuous monitoring as studies show that continuous

2015 EUnetHTA

107. Practice Parameter for Electrodiagnostic Studies in Ulnar Neuropathy at the Elbow

the standards, guidelines, and options for electrodiagnostic studies of UNE based on a critical review of the literature. Literature Review A Medline search was conducted for literature in English from 1983 through 1996 under the Medical Subject Headings (MeSH) (1) ulnar nerve, (2) electrodiagnosis, (3) nerve compression syndromes, (4) neural conduction, and (5) elbow. The initial search generated 282 article titles with abstracts. The abstracts were reviewed by two American Association of Electrodiagnostic (...) deviations (SD), from data derived from the reference population.8 - 2 Guidelines in Electrodiagnostic Medicine Definitions for Classification of Evidence 1. Class A evidence: studies that meet all six literature classification criteria, or five criteria in the case of studies only on normal control subjects. 2. Class B evidence: studies that meet four or five literature classification criteria, or less than five criteria in the case of studies only on normal control subjects. 3. Class C evidence

2015 American Association of Neuromuscular & Electrodiagnostic Medicine

108. Evidence Map of Acupuncture

, quality of life, exercise performance, hiccups, hot flushes, cancer, menopause-related effects, insomnia, cancer-related fatigue, nausea, cancer treatment-related adverse events, uremic pruritus, vasomotor menopausal symptoms, dry eye, dry mouth, premenstrual syndrome, erectile dysfunction, obesity, irritable bowel syndrome, constipation, Ménière’s disease, allergic rhinitis, tinnitus, restless legs, temporomandibular disorders, stroke, Bell’s palsy, fertility treatment, arthritis, Parkinson, uterine (...) of effective services to improve patient outcomes and to support V A clinical practice guidelines and performance measures, and • set the direction for future research to address gaps in clinical knowledge. In 2009, the ESP Coordinating Center was created to expand the capacity of QUERI Central Office and the four ESP sites by developing and maintaining program processes. In addition, the Center established a Steering Committee comprised of QUERI field-based investigators, V A Patient Care Services, Office

2014 Veterans Affairs Evidence-based Synthesis Program Reports

109. Acute Pain Management: Scientific Evidence

and implementation of clinical practice guidelines . https:// www.nhmrc.gov.au/guidelines-publications/cp30 Accessed 29 August 2014. painaustralia (2010) National Pain Strategy. Available from Painaustralia at: www.painaustralia.org.au Accessed 24 October 2015. Reardon DP , Anger KE, Szumita PM (2015) Pathophysiology, assessment, and management of pain in critically ill adults. Am J Health Syst Pharm 72(18):1531–43. Shipton EA (2014a) The transition of acute postoperative pain to chronic pain: Part 1 - Risk (...) , the Malaysian Association for the Study of Pain, the New Zealand Pain Society, the Pain Association of Singapore, the Royal Australasian College of Physicians, the Royal Australian and New Zealand College of Psychiatrists and the Royal Australasian College of Surgeons — and recommended to its members by the American Academy of Pain Medicine. Guidelines should be revised as further evidence accumulates (ideally every 5 years), and as there has been a continuing and substantial increase in the quantity

2015 Clinical Practice Guidelines Portal

110. Fluenz Tetra - influenza vaccine (live attenuated, nasal)

). As the addition of a fourth strain is not expected to significantly change the quality characteristics of the Q/LAIV, stability data of the T/LAIV were considered supportive for the Q/LAIV. The Drug Product stability data support the shelf-life at -25°C ± 5°C for up to 20 weeks prior to distribution and subsequent storage at 2°C to 8°C not to exceed 18 weeks. In accordance with EU GMP guidelines, any confirmed out of specification result, or significant negative trend, should be reported to the CHMP. GMO Like (...) , periodic safety update report and risk management plan. The same commitments as for Fluenz with respect to neurovirulence assays and neurovirulence monitoring are agreed for Fluenz Tetra. Pharmacodynamic drug interactions Pharmacodynamic drug interaction studies have not been conducted with Fluenz Tetra in accordance with “Note for Guidance on Preclinical Pharmacological and Toxicological Testing of Vaccines” (CPMP/SWP/465/95) and with “Guideline on Adjuvants in Vaccines for human use” (CHMP/VEG/134716

2013 European Medicines Agency - EPARs

111. Dry eye syndrome

information, see the CKS topic on . Past medical history of conditions associated with dry eye such as rosacea, psoriasis, atopy, Sjögren's syndrome, rheumatoid arthritis, systemic lupus erythematosus, scleroderma, menopause, lymphoma, chronic viral infections (for example HIV and hepatitis C), orbital radiation and neurological conditions (for example Parkinson disease or Bell’s palsy). Associated features indicative of an undiagnosed underlying condition such as dry mouth, dental cavities, oral ulcers (...) — abnormalities may indicate an alternative such as corneal ulcer or keratoconjunctivitis. For signs of associated conditions such as rosacea, acne, seborrhoeic dermatitis, rheumatoid arthritis, Sjogren’s syndrome, systemic lupus erythematosus, Raynaud’s phenomenon, thyroid eye disease, Bell’s palsy or Parkinson’s disease. Investigations Slit lamp examination of the cornea and tear film in addition to investigations such as Schirmer’s test are needed for a formal diagnosis of dry eye syndrome. The equipment

2017 NICE Clinical Knowledge Summaries

112. Stroke and TIA

known as stroke mimics) can present with similar clinical features to stroke and TIA. These include: Toxic/metabolic disturbance such as: Hypoglycaemia. Drug and alcohol toxicity. Conditions which can cause dizziness or disturbed balance such as: Syncope. Peripheral vestibular disturbance — vertigo or dizziness. Neurological conditions such as: Seizure. Migraine with aura. Demyelination. Peripheral neuropathies such as Bell’s palsy. Spinal epidural haematoma. Trauma Systemic or local Infection (...) up should be arranged to optimize secondary prevention lifestyle and drug strategies. Have I got the right topic? Have I got the right topic? From age 16 years onwards. This CKS topic is largely based on the clinical guidelines Stroke rehabilitation in adults [ ] and National clinical guideline for stroke prepared by the Intercollegiate Stroke Working Party [ ]. This CKS topic covers the primary care assessment and management of adults presenting with suspected acute stroke or transient ischaemic

2017 NICE Clinical Knowledge Summaries

113. Vertigo

audience for this CKS topic is healthcare professionals working within the NHS in the UK, and providing first contact or primary health care. How up-to-date is this topic? How up-to-date is this topic? Changes Changes December 2017 — revised. A literature search was conducted in August 2017 to identify evidence-based guidelines, UK policy, systematic reviews, and key RCTs published since the last revision of the topic. There have been structural changes to the topic and a new section has been created (...) . The evidence base has been reviewed in detail, and recommendations are clearly justified and transparently linked to the supporting evidence. Update Update New evidence New evidence Evidence-based guidelines No new evidence-based guidelines since 1 December 2017. HTAs (Health Technology Assessments) No new HTAs since 1 December 2017. Economic appraisals No new economic appraisals relevant to England since 1 December 2017. Systematic reviews and meta-analyses No new systematic reviews published since 1

2017 NICE Clinical Knowledge Summaries

114. Vestibular neuronitis

is healthcare professionals working within the NHS in the UK, and providing first contact or primary health care. How up-to-date is this topic? How up-to-date is this topic? Changes Changes November 2017 — reviewed. A literature search was conducted in August 2017 to identify evidence-based guidelines, UK policy, systematic reviews, and key RCTs published since the last revision of this topic. Minor changes have been made to the sections on diagnosis and symptomatic treatment and a link to patient (...) to February 2011 — this is a new CKS topic. The evidence-base has been reviewed in detail, and recommendations are clearly justified and transparently linked to the supporting evidence. Update Update New evidence New evidence Evidence-based guidelines No new evidence-based guidelines since 1 August 2017. HTAs (Health Technology Assessments) No new HTAs since 1 August 2017. Economic appraisals No new economic appraisals relevant to England since 1 August 2017. Systematic reviews and meta-analyses No new

2017 NICE Clinical Knowledge Summaries

115. Vestibular Assessment ? Eye movement Recordings

a permanent record to document nystagmus and eye movements, allowing for their detailed analysis. The aim of this recommended procedure is to clarify the methodology and interpretation of findings. This should allow a standardised method to be used in most cases. Alternative methodologies may be required in certain cases, but there must be robust evidence to justify doing so. 3.3. Scope This protocol provides guidelines for testing using ENG or VNG with commercially available systems. The test battery (...) ) and Bell’s phenomenon. 4.4. Visual impairments and ophthalmic disorders Blindness or severe visual impairment may affect the results. If a patient with significant refractive error cannot clearly see any given target, they should wear their spectacles and eye movements should be recorded by ENG. In the case of ptosis, the eyelids can be held open for short periods using micropore tape. The patient’s eyes should be examined initially by direct observation to check that eye movements are conjugate. Observe

2016 British Society of Audiology

116. Neoadjuvant Treatment of HER2 Positive Early High-risk and Locally Advanced Breast Cancer

ovary cells or any component of the atezolizumab formulation Patients with prior allogeneic stem cell or solid organ transplantation History of autoimmune disease including, but not limited to, systemic lupus erythematosus, rheumatoid arthritis, inflammatory bowel disease, vascular thrombosis associated with antiphospholipid syndrome, Wegener's granulomatosis, Sjögren's syndrome, Bell's palsy, Guillain-Barré syndrome, multiple sclerosis, vasculitis, or glomerulonephritis History of idiopathic (...) to ASCO/CAP guidelines 2013 [defined as IHC 3+ or ISH positive (by gene copy number or HER2 gene/CEP17 ratio of 2 or greater)] Known estrogen (ER) and progesterone receptor (PgR) Availability of a representative paraffin-embedded (FFPE) tumor block taken at diagnostic biopsy for central confirmation of HER2 eligibility, for assessment of ER, PgR, Ki67 and PD-L1 expression and for biomarker evaluation is mandatory. Note: the diagnostic biopsy of the breast lesion may have been taken before the required

2018 Clinical Trials

117. Perinatal care at the threshold of viability

Perinatal care at the threshold of viability Perinatal care at the threshold of viability Queensland Clinical Guideline: Perinatal care at the threshold of viability Refer to online version, destroy printed copies after use Page 2 of 35 Document title: Perinatal care at the threshold of viability Publication date: September 2014 Document number: MN14.32-V1-R19 Document supplement: The document supplement is integral to and should be read in conjunction with this guideline. Amendments Full (...) version history is supplied in the document supplement. Amendment date: New document Replaces document: New document Author: Queensland Clinical Guidelines Audience: Health professionals in Queensland public and private maternity services Review date: September 2019 Endorsed by: Queensland Clinical Guidelines Steering Committee Statewide Maternity and Neonatal Clinical Network Contact: Email: Guidelines@health.qld.gov.au URL: www.health.qld.gov.au/qcg Disclaimer These guidelines have been prepared

2014 Queensland Health

118. Diagnosis and Treatment of Adult Isthmic Spondylolisthesis

Diagnosis and Treatment of Adult Isthmic Spondylolisthesis This clinical guideline should not be construed as including all proper methods of care or excluding or other acceptable methods of care reason- ably directed to obtaining the same results. The ultimate judgment regarding any specific procedure or treatment is to be made by the physi- cian and patient in light of all circumstances presented by the patient and the needs and resources particular to the locality or institution. 1 Introduct (...) Ion /Gu Idel Ine Methodolo Gy Diagnosis and Treatment of Adult Isthmic Spondylolisthesis | NASS Clinical Guidelines NASS Evidence-Based Clinical Guidelines Committee D. Scott Kreiner, MD Committee Co- Chair and Natural History Section Chair Jamie Baisden, MD Diagnosis/Imaging Section Chair Daniel Mazanec, MD Medical/Interventional Treatment Section Chair Rakesh Patel, MD Surgical Treatment Section Chair Evidence-Based Clinical Guidelines for Multidisciplinary Spine Care Diagnosis and Treatment

2014 North American Spine Society

119. Transitions of Care for Children with Special Health Care Needs

practice guidelines and other quality enhancement tools, or as a basis for reimbursement and coverage policies. AHRQ or U.S. Department of Health and Human Services endorsement of such derivative products may not be stated or implied. This document is in the public domain and may be used and reprinted without permission except those copyrighted materials noted, for which further reproduction is prohibited without the specific permission of copyright holders. Persons using assistive technology may (...) transition processes and medical management of adults with childhood-onset chronic diseases. 24,28-30 Additionally, CSHCN face broader challenges, including issues related to insurance, entitlements, guardianship, and eligibility for adult community-based services. 2,31 Nonetheless, several guidelines, panels, and other groups coalesce around the need for good transition care for this population in particular. Healthy People 2010 32 includes a goal that all young people with special health care needs

2014 Effective Health Care Program (AHRQ)

120. Management of Thyroid Cancer

Management of Thyroid Cancer CLINICAL ENDOCRINOLOGY VOLUME 81 SUPPLEMENT 1 JULY 2014 THE CLINICAL JOURNAL OF THE SOCIETY FOR ENDOCRINOLOGY AND THE ENDOCRINE SOCIETY OF AUSTRALIA British Thyroid Association Guidelines for the Management of Thyroid CancerGuidelines for the management of thyroid cancer Third edition British Thyroid Association July 2014 Perros P, Colley S, Boelaert K, Evans C, Evans RM, Gerrard GE, Gilbert JA, Harrison B, Johnson SJ, Giles TE, Moss L, Lewington V , Newbold KL (...) , Taylor J, Thakker RV , Watkinson J, Williams GR cen_frontmatter.indd i cen_frontmatter.indd i 6/27/2014 3:52:19 PM 6/27/2014 3:52:19 PMii Acknowledgements Grateful thanks are expressed to the many reviewers of these guidelines. These included leading international experts in thyroid cancer, hospital specialists, and general practitioners. They devoted much time and care to considering the document and their recommendations and suggestions for improvements were most valuable. Special thanks to Dr

2014 British Thyroid Association

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