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aspirin and Reye syndrome

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41. Prostate Cancer

. 29. Esposito, K., et al. Effect of metabolic syndrome and its components on prostate cancer risk: meta-analysis. J Endocrinol Invest, 2013. 36: 132. 30. Blanc-Lapierre, A., et al. Metabolic syndrome and prostate cancer risk in a population-based case-control study in Montreal, Canada. BMC Public Health, 2015. 15: 913. 31. Preston, M.A., et al. Metformin use and prostate cancer risk. Eur Urol, 2014. 66: 1012. 32. Freedland, S.J., et al. Statin use and risk of prostate cancer and high-grade (...) : A Systematic Review and Meta-analysis. JAMA Intern Med, 2017. 177: 1273. 66. Cremers, R.G., et al. Self-reported acne is not associated with prostate cancer. Urol Oncol, 2014. 32: 941. 67. Huang, T.B., et al. Aspirin use and the risk of prostate cancer: a meta-analysis of 24 epidemiologic studies. Int Urol Nephrol, 2014. 46: 1715. 68. Bhindi, B., et al. The impact of the use of aspirin and other nonsteroidal anti-inflammatory drugs on the risk of prostate cancer detection on biopsy. Urology, 2014. 84: 1073

2018 European Association of Urology

42. Cardiovascular Disease and Breast Cancer: Where These Entities Intersect: A Scientific Statement From the American Heart Association

toxicity of the anthracyclines can manifest early or late after exposure. The early manifestations could be related to inflammation resulting in a pericarditis-myocarditis syndrome, whereas the late manifestations are related to actual myocyte damage that results in the clinical syndrome of HF. Cell death has been confirmed by rising troponin levels. The risk of HF increases with increasing cumulative doses of anthracyclines; for instance, with doxorubicin, there is an ≈5% risk at a dose of 400 mg/m 2

2018 American Heart Association

43. Imaging Guidelines

warfarin or aspirin developed delayed intracerebral bleeding, none of which required intervention. 3,8,9 Studies examining individual oral anticoagulant or antiplatelet agents yield similar results. Patients taking warfarin who had supra- therapeutic INR levels (greater than 3) had an increased risk of developing a new bleed following an initial negative head CT. A recent meta-analysis of 1,594 patients on pre-injury warfarin with a normal initial head CT estimated a 0.6 percent pooled incidence (...) head CT scan, unlike patients who are not on anticoagulation. In patients on platelet inhibitors alone (aspirin, clopidogrel) more contradictory data have been reported. Many studies and algorithms considered aspirin to be a low-risk medication; however, recent data question that assertion. 11 In a prospective observational study of 265 patients with ICH on initial head CT, both aspirin and clopidogrel were identified as independent predictors of mortality and the need for neurosurgical

2018 American College of Surgeons

44. Methodological quality and synthesis of case series and case reports Full Text available with Trip Pro

of Recommendations, Assessment, Development and Evaluation (GRADE) approach clearly separates the certainty of evidence from the strength of recommendation. This separation allows decision-making based on lower levels of evidence. For example, despite low certainty evidence (derived from case series) regarding the association between aspirin and Reye’s syndrome in febrile children, a strong recommendation for using acetaminophen over aspirin is possible. GRADE literature also describes five paradigmatic (...) patient may allow narrative or quantitative synthesis. Narrative synthesis A systematic review of the cases with the rare syndrome of lipodystrophy was able to suggest core and supportive clinical features and narratively summarised data on available treatment approaches. Another systematic review of 172 cases of the infrequently encountered glycogenic hepatopathy was able to characterise for the first time patterns of liver enzymes and hepatic injury in this disease. Quantitative synthesis

2018 Evidence-Based Medicine

45. Policy on Acute Pediatric Dental Pain Management

are contraindicated for pediatric pain management in most situations because, if administered during a viral illness, the potential exists for a serious condition known as Reye syndrome. 13 Acetaminophen lacks anti-inflammatory properties but can be a non-opioid alternative when NSAIDs are contraindicated. 11 Acetaminophen is found as a single agent and also in combination with other drugs. Overdose of acetaminophen is a potential pediatric emergency, and the maximum daily dose should be observed, especially when (...) be administered on a regular schedule during the first 36 to 48 hours to create stable plasma levels of analgesics and decrease the chance of breakthrough pain. 11,12 Treatment of postoperative pain may include opioid anal- gesics and non-opioid analgesics. Since most cases of postoper- ative pain include an inflammatory component, nonsteroidal anti-inflammatory agents ( NSAIDs) are considered first line agents in the treatment of acute mild to moderate postoper- ative pain. 11 Aspirin-containing analgesics

2017 American Academy of Pediatric Dentistry

47. Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Scientific Statement for Health Professionals From the American Heart Association Full Text available with Trip Pro

children. It is most common in winter and early spring in North America. Predisposing factors have been reported inconsistently. Nonspecific symptoms are common in the 10 days before diagnosis. In Japan, the recurrence rate is ≈3%, and the relative risk in siblings is 10-fold higher. The case fatality rate is <0.1% in Japan. Coronary artery aneurysms from KD account for 5% of acute coronary syndromes (ACS) in adults <40 years of age. Genetics Evidence for a genetic component to KD susceptibility (...) infections (eg, adenovirus, enterovirus) Staphylococcal and streptococcal toxin-mediated diseases (eg, scarlet fever and toxic shock syndrome) Drug hypersensitivity reactions, including Stevens Johnson syndrome Systemic onset juvenile idiopathic arthritis With epidemiologic risk factors: Rocky Mountain spotted fever or other rickettsial infections Leptospirosis BCG indicates bacillus Calmette-Guérin; CXR, chest radiography; and KD, Kawasaki disease. Principal Clinical Findings The diagnosis of classic KD

2017 American Heart Association

48. Diagnosis and treatment of respiratory illness in children and adults.

should not be used for longer than 72 hours, owing to the potential for rebound congestion. Aspirin is not recommended for children because of the risk of Reye's syndrome. Aspirin, ibuprofen and naproxen should be avoided by persons who are not eating well (risk of gastrointestinal upset), have a history of peptic ulcer or related disorder, or have aspirin-sensitive asthma, coronary artery disease or have renal dysfunction. Avoid using honey preparations for children under one year because

2017 National Guideline Clearinghouse (partial archive)

51. CRACKCast E130 – Viruses

to this disease. Neurologic complications are rare but can include encephalitis, aseptic meningitis, transverse myelitis, and Reye syndrome (the association of aspirin use with Reye syndrome, a progressive encephalopathy). [7] Describe clinical presentations of CMV infections and treatment The spectrum of illness caused by CMV ranges from asymptomatic to severe disseminated disease in the immunocompromised patient. CMV is particularly harmful in pregnant patients, because it can lead to congenital infection (...) , causing profound neurologic defects and permanent hearing loss. CMV is present in breast milk, saliva, feces, urine, semen, cervical secretions, and blood. The virus spreads via prolonged exposure to these body fluids. After primary infection, CMV establishes a lifelong latent infection. Clinical presentation: Primary infection = usually subclinical Some will develop a mononucleosis like syndrome. The illness can last from 2 to 6 weeks and is characterized by fever, fatigue, malaise, myalgia

2017 CandiEM

52. Interventions Targeting Sensory Challenges in Children with Autism Spectrum Disorder - An Update

and cerebellum of three older men with fragile X syndrome. Mol Autism. 2011;2(1):2. doi: 10.1186/2040-2392-2-2. PMID: 21303513.X-1 653. Greer RD, Pistoljevic N, Cahill C, et al. Effects of conditioning voices as reinforcers for listener responses on rate of learning, awareness, and preferences for listening to stories in preschoolers with autism. Anal Verbal Behav. 2011;27(1):103- 24. PMID: 22532758.X-1, X-3, X-4 D-56 654. Griffith GM, Hastings RP, Oliver C, et al. Psychological well-being in parents (...) of children with Angelman, Cornelia de Lange and Cri du Chat syndromes. J Intellect Disabil Res. 2011 Apr;55(4):397-410. doi: 10.1111/j.1365-2788.2011.01386.x. PMID: 21323782.X-1 655. Grow LL, Carr JE, Kodak TM, et al. A comparison of methods for teaching receptive labeling to children with autism spectrum disorders. J Appl Behav Anal. 2011 Fall;44(3):475-98. doi: 10.1901/jaba.2011.44-475. PMID: 21941380.X-3, X-4 656. Guénolé F, Baleyte J-M. Melatonin for sleep-disturbed children with autism spectrum

2017 Effective Health Care Program (AHRQ)

54. HTA of smoking cessation interventions

for the National Clinical Programme for Acute Coronary Syndrome, HSE Dr Paul Kavanagh Specialist in Public Health Medicine, HSE Dr Marcus Kennedy Interventional Pulmonologist, Consultant Respiratory and General Physician, Cork University Hospital Prof Deirdre Madden Professor, Faculty of Law, University College Cork Ms Patricia McQuillan Practice Nurse Development Co-ordinator, Asthma and COPD Clinical Programme, HSE Dr Patrick Moran Senior HTA Analyst, HIQA (Project Lead) Health Technology Assessment (HTA (...) . Smoking during pregnancy is harmful. It is associated with an increased risk of congenital anomalies, preterm birth, intrauterine fetal growth restriction, placental abruption, stillbirth, sudden infant death syndrome, respiratory infection, adverse cognitive and behavioural outcomes in infancy, and the development of chronic disease in adulthood. Evidence shows that smokers with mental health disorders smoke more heavily, are more nicotine dependent, and have smoked for longer than smokers who do

2017 Health Information and Quality Authority

55. Summary of the National Advisory Committee on Immunization (NACI) statement on seasonal influenza vaccine for 2015-2016

and are associated with an increased risk of aspiration morbid obesity (BMI ≥40) children and adolescents (aged 6 months to 18 years) with the following conditions: neurologic or neurodevelopment conditions (including seizure disorders, febrile seizures and isolated developmental delay) undergoing treatment for long periods with acetylsalicylic acid, because of the potential increase of Reye's syndrome associated with influenza. People of any age who are residents of nursing homes and other chronic care (...) , as well as a revised definition for oculo-respiratory syndrome which, when it occurs, should be reported as an adverse event following immunization (AEFI) to local public health officials. Conclusion: Vaccination is the safest, longest lasting and most effective way to prevent influenza. Introduction Every year, the National Advisory Committee on Immunization (NACI) provides the Public Health Agency of Canada with recommendations on seasonal influenza vaccines for the upcoming season as part of its

2015 CPG Infobase

56. Regular exploratory examination of the need for DMP revision - a feasibility study using the example of the DMP "CHD"

angiotensin converting enzyme (Angiotensin-Konversionsenzym) ACS acute coronary syndrome (akutes Koronarsyndrom) AGREE Appraisal of Guidelines for Research & Evaluation AHA American Heart Association AK Antikörper AkdÄ Arzneimittelkommission der deutschen Ärzteschaft AP Angina Pectoris ARB Angiotensin-Rezeptorblocker ASS Acetylsalicylsäure AT1-Rezeptorblocker Angiotensin-1-Rezeptorblocker AWMF Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften BfArM Bundesinstitut für Arzneimittel

2015 Institute for Quality and Efficiency in Healthcare (IQWiG)

58. Headaches in over 12s: diagnosis and management

-and- conditions#notice-of-rights). Page 19 of 30P Positiv ositive diagnosis e diagnosis A diagnosis based on the typical clinical picture that does not require any further investigations to exclude alternative explanations for a patient's symptoms. [7] For information on referral for suspected tumours of the brain or central nervous system see the NICE guideline on suspected cancer. [8] Because of an association with Reye's syndrome, preparations containing aspirin should not be offered to people aged under (...) to the possibility of medication overuse headache in people whose headache developed or worsened while they were taking the following drugs for 3 months or more: triptans, opioids, ergots or combination analgesic medications on 10 days per month or more or or paracetamol, aspirin or an NSAID, either alone or any combination, on 15 days per month or more. [2012] [2012] Management All headache disorders All headache disorders Do not refer people diagnosed with tension-type headache, migraine, cluster headache

2012 National Institute for Health and Clinical Excellence - Clinical Guidelines

59. Acute pain management: scientific evidence (3rd Edition)

: Scientific Evidence xv CONTENTS 9. SPECIFIC CLINICAL SITUATIONS 237 9.1 Postoperative pain 237 9.1.1 Risks of acute postoperative neuropathic pain 237 9.1.2 Acute postamputation pain syndromes 238 9.1.3 Other postoperative pain syndromes 240 9.1.4 Day-stay or short-stay surgery 242 9.1.5 Cranial neurosurgery 245 9.2 Acute pain following spinal cord injury 247 9.3 Acute burn injury pain 249 9.3.1 Management of procedural pain 250 9.3.2 Non-pharmacological pain management 251 9.4 Acute back pain 252 9.5 (...) 9.7.3 Breakthrough pain 285 9.7.4 Postoperative and procedural pain 286 9.7.5 Acute cancer pain due to bone involvement 287 9.7.6 Other acute cancer pain syndromes 288 9.7.7 Interventional therapies for acute cancer pain 289 9.8 Acute pain management in intensive care 290 9.8.1 Pain assessment in the intensive care unit 291 9.8.2 Non-pharmacological measures 291 9.8.3 Pharmacological treatment 291 9.8.4 Guillain-Barre syndrome 292 9.8.5 Procedure-related pain 293 9.9 Acute pain management

2015 National Health and Medical Research Council

60. Migraine

migraine includes: Trigger avoidance (where possible) and lifestyle changes. Drug treatment with simple analgesia (such as paracetamol, ibuprofen or aspirin), or a triptan or combination therapy with a triptan and paracetamol or a nonsteroidal anti-inflammatory drug. An anti-emetic (prochlorperazine or metoclopramide) may be added even in the absence of nausea or vomiting. Preventative treatment (such as propranolol or topiramate) may be considered in adults who are not pregnant or breastfeeding (...) of migraine (for example cyclical vomiting syndrome and abdominal migraine). There are separate CKS topics on , , , , , , and . The target audience for this CKS topic is healthcare professionals working within the NHS in the UK, and providing first contact or primary health care. How up-to-date is this topic? How up-to-date is this topic? Changes Changes April 2019 — reviewed. A literature search was conducted in March 2019 to identify evidence-based guidelines, UK policy, systematic reviews, and key

2019 NICE Clinical Knowledge Summaries

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