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aspirin and Reye syndrome

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321. Reye's Syndrome Full Text available with Trip Pro

Reye's Syndrome The author defines and discusses Reye's syndrome and the hypotheses relating to its causes and associating its incidence with that of chickenpox and influenza A and B. The recent decline in the incidence of Reye's syndrome appears to be related to the reduced use of Aspirin in children and adolescents. Although evidence so far is circumstantial, North American P(a)ediatric Associations have indicated that Aspirin should not be used to control fever in children who have viral

1987 Canadian Family Physician

322. The changing clinical pattern of Reye's syndrome 1982-1990. Full Text available with Trip Pro

scoring subgroup which also contained those cases most likely to resemble 'classical' Reye's syndrome and to have received aspirin. This study provides further evidence for the role of aspirin in a subset of cases meeting the standard diagnostic criteria for Reye's syndrome and supports the need to consider this disorder as a heterogeneous group of conditions including Reye-like inherited metabolic disorders. (...) % after June 1986, whereas those in the high category fell by 79%. High scorers were more likely to have received aspirin (p < 0.0001) and were older than intermediate and low scorers (p < 0.008). No relation was identified between score and season of onset.The decline in Reye's syndrome after the aspirin warnings cannot be explained entirely, as has been proposed, by improved diagnosis of 'Reye-like' inherited metabolic and other disorders: this would not account for the greater decline of the high

1996 Archives of Disease in Childhood

323. Reye's syndrome. Full Text available with Trip Pro

Reye's syndrome. 7819876 1995 02 10 2018 11 13 0959-8138 309 6966 1994 Nov 26 BMJ (Clinical research ed.) BMJ Reye's syndrome. 1443 Casteels-Van Daele M M Eggermont E E eng Comment Letter England BMJ 8900488 0959-8138 0 Antiemetics R16CO5Y76E Aspirin AIM IM BMJ. 1994 Aug 6;309(6951):411 8081168 Antiemetics adverse effects Aspirin adverse effects Child Humans Reye Syndrome chemically induced 1994 11 26 1994 11 26 0 1 1994 11 26 0 0 ppublish 7819876 PMC2541375 N Engl J Med. 1983 Jul 21;309(3):133

1994 BMJ : British Medical Journal

324. Co-existence of hepatitis A and adult Reye's syndrome. Full Text available with Trip Pro

Co-existence of hepatitis A and adult Reye's syndrome. Reye's syndrome is most frequently seen in children but has also been described in adults. This syndrome is usually associated with ingestion of 5-aminosalicylates (ASA) or infection with influenza A, influenza B, or varicella virus. A case of Reye's syndrome in a 47 year old, previously healthy woman precipitated by ingestion of ASA and acute hepatitis A virus infection is described. Reye's syndrome was diagnosed on the basis of her (...) to ASA, may have precipitated Reye's syndrome in this patient. The association between hepatitis A and Reye's syndrome has not been reported before. As hepatitis A virus infection is not sought routinely in patients with Reye's syndrome, the frequency of this association is unknown.

1997 Gut

325. Aspirin, Reye syndrome, Kawasaki disease, and allergies; a reconsideration of the links Full Text available with Trip Pro

Aspirin, Reye syndrome, Kawasaki disease, and allergies; a reconsideration of the links 15557065 2004 12 20 2013 11 21 1468-2044 89 12 2004 Dec Archives of disease in childhood Arch. Dis. Child. Aspirin, Reye syndrome, Kawasaki disease, and allergies; a reconsideration of the links. 1178 van Bever H P HP Quek S C SC Lim T T eng Letter England Arch Dis Child 0372434 0003-9888 0 Anti-Inflammatory Agents, Non-Steroidal R16CO5Y76E Aspirin AIM IM Anti-Inflammatory Agents, Non-Steroidal adverse (...) effects Aspirin adverse effects Drug Hypersensitivity etiology Humans Mucocutaneous Lymph Node Syndrome drug therapy Reye Syndrome chemically induced 2004 11 24 9 0 2004 12 21 9 0 2004 11 24 9 0 ppublish 15557065 89/12/1178-a 10.1136/adc.2004.055681 PMC1719775

2004 Archives of Disease in Childhood

326. Reye's syndrome revisited : Outdated concept of Reye's syndrome was used Full Text available with Trip Pro

Reye's syndrome revisited : Outdated concept of Reye's syndrome was used 11872565 2002 03 18 2018 11 13 1756-1833 324 7336 2002 Mar 02 BMJ (Clinical research ed.) BMJ Reye's syndrome revisited. Outdated concept of Reye's syndrome was used. 546 Casteels-Van Daele M M Wouters C C Van Geet C C McGovern M C MC Glasgow J F T JF Stewart M C MC eng Comment Letter England BMJ 8900488 0959-8138 0 Anti-Inflammatory Agents, Non-Steroidal R16CO5Y76E Aspirin AIM IM BMJ. 2001 Jun 30;322(7302):1591-2 11431304 (...) Anti-Inflammatory Agents, Non-Steroidal adverse effects Aspirin adverse effects Child Diagnosis, Differential Humans Reye Syndrome classification etiology 2002 3 2 10 0 2002 3 19 10 1 2002 3 2 10 0 ppublish 11872565 PMC1122458 J R Soc Med. 1986 Oct;79(10):596-8 3537289 Biochim Biophys Acta. 1999 May 31;1454(1):115-25 10354521 J Pediatr. 1997 Feb;130(2):300-4 9042136 Arch Dis Child. 1996 May;74(5):400-5 8669954 Am J Dis Child. 1989 Oct;143(10):1181-5 2801659 BMJ. 2001 Jun 30;322(7302):1591-2

2002 BMJ : British Medical Journal

327. Reye's syndrome and aspirin. Full Text available with Trip Pro

Reye's syndrome and aspirin. 3612668 1987 09 04 2018 11 13 0141-0768 80 5 1987 May Journal of the Royal Society of Medicine J R Soc Med Reye's syndrome and aspirin. 325-6 Rowe P H PH eng Letter England J R Soc Med 7802879 0141-0768 R16CO5Y76E Aspirin IM Aspirin adverse effects Humans Reye Syndrome chemically induced 1987 5 1 1987 5 1 0 1 1987 5 1 0 0 ppublish 3612668 PMC1290825 Gastroenterology. 1977 Nov;73(5):995-9 302812 Am J Dis Child. 1982 Nov;136(11):971-2 7124701 J Pharmacol Exp Ther

1987 Journal of the Royal Society of Medicine

328. A survey of aspirin use and Reye's syndrome awareness among parents. Full Text available with Trip Pro

A survey of aspirin use and Reye's syndrome awareness among parents. A national telephone survey of 1,155 parents of children 19 years of age and younger solicited patterns of medication use during episodes of childhood flu and chicken pox. During the previous two years, 6 per cent of the parents whose children had chicken pox and 16 per cent of parents whose children had flu administered aspirin. Approximately 12 per cent of the total sample said they would give their child aspirin (...) if their child were to get the flu or chicken pox today. About half (53 per cent) were aware of the contraindication against aspirin use and 40 per cent could spontaneously recall the name Reye's Syndrome (RS). When measured by a recognition test, 84 per cent of the sample said they had heard of RS. People who continued to believe that aspirin was an appropriate medication were more likely to have treated older children. The RS contraindication for aspirin should be emphasized for teenagers in future public

1986 American Journal of Public Health

329. Aspirin and Reye's syndrome — do parents know? Full Text available with Trip Pro

Aspirin and Reye's syndrome — do parents know? Amid growing concern over the association between aspirin and Reye's syndrome, the Aspirin Foundation has recently mounted a publicity campaign advising against the use of aspirin in children. Of 50 parents questioned at a children's ward of a district general hospital, 46 (92%) had heard of the publicity, 38 via the television. The number of parents who would give aspirin to their child had dropped significantly from 45 before the campaign (...) to five after it (P<0.001); only one parent chose to ignore the advice. The media, particularly television, is again shown to be a potent means of publicity. Despite the very high response to the advice about aspirin none of the parents mentioned Reye's syndrome as the reason.

1987 The Journal of the Royal College of General Practitioners

330. Reye's syndrome and aspirin. Full Text available with Trip Pro

Reye's syndrome and aspirin. 3806491 1987 03 19 2018 11 13 0035-8797 36 290 1986 Sep The Journal of the Royal College of General Practitioners J R Coll Gen Pract Reye's syndrome and aspirin. 418-21 Mann R D RD eng Journal Article England J R Coll Gen Pract 7503107 0035-8797 R16CO5Y76E Aspirin IM Aspirin adverse effects Child Humans Pharmacy and Therapeutics Committee Reye Syndrome chemically induced United Kingdom 1986 9 1 1986 9 1 0 1 1986 9 1 0 0 ppublish 3806491 PMC1960510 Lancet. 1979 Nov

1986 The Journal of the Royal College of General Practitioners

331. Trends in the incidence of Reye's syndrome and the use of aspirin. Full Text available with Trip Pro

illnesses were 17 times more likely to have received aspirin before admission to hospital in 1985/6 compared with 1988/9. Only 21 Belfast parents (40%) and 13 London parents (27%) had heard of Reye's syndrome and only 12 in Belfast (23%) and seven in London (15%) knew of its association with aspirin, suggesting a continuing need for public education. Cases of Reye's syndrome declined both in numbers (from a peak of 79 in 1983/4 to 19 in 1988/9) and in median age. Of the 418 reported cases, the diagnosis (...) Trends in the incidence of Reye's syndrome and the use of aspirin. In 1986 there was a public warning in the United Kingdom about a link between the consumption of aspirin and Reye's syndrome. To find out if the use of aspirin and paracetamol in children had altered, and whether the incidence of Reye's syndrome had changed since a previous study, parents were interviewed in Belfast and London, and the British Reye's Syndrome Surveillance System data were reviewed. Children with febrile

1990 Archives of Disease in Childhood

332. Reye's syndrome and aspirin: lest we forget Full Text available with Trip Pro

Reye's syndrome and aspirin: lest we forget 11431304 2001 07 26 2018 11 13 0959-8138 322 7302 2001 Jun 30 BMJ (Clinical research ed.) BMJ Lesson of the week: Reye's syndrome and aspirin: lest we forget. 1591-2 McGovern M C MC Royal Belfast Hospital for Sick Children, Belfast BT12 6BE. Glasgow J F JF Stewart M C MC eng Case Reports Journal Article Research Support, Non-U.S. Gov't England BMJ 8900488 0959-8138 0 Anti-Inflammatory Agents, Non-Steroidal R16CO5Y76E Aspirin AIM IM BMJ. 2002 Mar 2;324 (...) (7336):546 11872565 Anti-Inflammatory Agents, Non-Steroidal adverse effects Aspirin adverse effects Child Contraindications Humans Infant Male Reye Syndrome chemically induced diagnosis 2001 6 30 10 0 2001 7 28 10 1 2001 6 30 10 0 ppublish 11431304 PMC1120628 Arch Dis Child. 1988 Jul;63(7):857-66 3415311 N Engl J Med. 1999 Sep 9;341(11):845-6; author reply 846-7 10490385 N Engl J Med. 1999 May 6;340(18):1377-82 10228187 Milbank Q. 1992;70(1):155-82 1316991 J Pediatr. 1985 Dec;107(6):877-80 4067744 N

2001 BMJ : British Medical Journal

333. Reye's Syndrome and Salicylates Full Text available with Trip Pro

Reye's Syndrome and Salicylates 18749664 2010 06 30 2018 11 13 0093-0415 141 5 1984 Nov The Western journal of medicine West. J. Med. Reye's Syndrome and Salicylates. 690 Sacks E M EM Family Practice, Valley Medical Group of Lompoc, Inc Lompoc, CA 93436. eng Journal Article United States West J Med 0410504 0093-0415 1984 11 1 0 0 1984 11 1 0 1 1984 11 1 0 0 ppublish 18749664 PMC1011198 West J Med. 1984 Aug;141(2):206-9 6495727

1984 Western Journal of Medicine

334. ASA and Reye's syndrome: an update. Full Text available with Trip Pro

ASA and Reye's syndrome: an update. 6616371 1983 11 23 2013 11 21 0008-4409 129 7 1983 Oct 01 Canadian Medical Association journal Can Med Assoc J ASA and Reye's syndrome: an update. 677 Liston A J AJ eng Letter Canada Can Med Assoc J 0414110 0008-4409 R16CO5Y76E Aspirin AIM IM Adolescent Aspirin adverse effects Child Humans Reye Syndrome chemically induced 1983 10 1 1983 10 1 0 1 1983 10 1 0 0 ppublish 6616371 PMC1875424

1983 Canadian Medical Association Journal

335. Induction of omega-oxidation of monocarboxylic acids in rats by acetylsalicylic acid. Full Text available with Trip Pro

Induction of omega-oxidation of monocarboxylic acids in rats by acetylsalicylic acid. The accumulation of dicarboxylic acids, particularly long chain, is a prominent feature of Reye's syndrome and diseases of peroxisomal metabolism. We assessed the omega-oxidation of a spectrum of fatty acids in rats and asked whether pretreatment of rats with aspirin, which is known to predispose children to Reye's syndrome, would affect omega-oxidation of long chain fatty acids. We found that aspirin (...) increased liver free fatty acids and increased the capacity for omega-oxidation three- to sevenfold. Omega-oxidation of long chain substrate was stimulated to a greater degree than medium chain substrate and was apparent within one day of treatment, at serum aspirin concentrations below the therapeutic range in humans. The apparent Km for lauric acid was 0.9 microM and 12 microM for palmitate. We also found a difference in the storage stability of activity toward medium and long chain substrate

1991 Journal of Clinical Investigation

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