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141. Antibiotic Prophylaxis Is Not Required for Endoscopic Ultrasonography-Guided Fine-Needle Aspiration of Pancreatic Cystic Lesions, Based on a Randomized Trial Full Text available with Trip Pro

Antibiotic Prophylaxis Is Not Required for Endoscopic Ultrasonography-Guided Fine-Needle Aspiration of Pancreatic Cystic Lesions, Based on a Randomized Trial Antibiotic Prophylaxis Is Not Required for Endoscopic Ultrasonography-Guided Fine-Needle Aspiration of Pancreatic Cystic Lesions, Based on a Randomized Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced (...) management software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Gastroenterology Actions . 2020 May;158(6):1642-1649.e1. doi: 10.1053/j.gastro.2020.01.025. Epub 2020 Jan 20. Antibiotic Prophylaxis Is Not Required for Endoscopic Ultrasonography-Guided Fine-Needle Aspiration of Pancreatic Cystic Lesions, Based on a Randomized Trial , , , , , , , , , , , , , Affiliations Expand Affiliations 1

2020 EvidenceUpdates

142. Antimicrobial prescribing: meropenem with vaborbactam

/50) of people receiving Antimicrobial prescribing: meropenem with vaborbactam (ES21) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 5 of 7meropenem with vaborbactam, and 44.0% (11/25) of people receiving best available antibiotic treatment. Adverse events leading to study treatment discontinuation occurred in 10.0% (5/50) and 12.0% (3/25) of people respectively. Statistical analyses were not reported for safety (...) for injection (Drug T ariff, October 2019). The cost of 1 day's treatment with 2 g (2 vials) every 8 hours is £106.68. The manufacturer of meropenem with vaborbactam (Menarini) anticipates that usage will be low, following the principles of good antimicrobial stewardship, and will be under the guidance of a microbiologist. A wide range of antibiotics, alone or in combination, are used for treating cUTI, acute pyelonephritis, cIAI, HAP and VAP , and regimens may be changed based on response to treatment

2019 National Institute for Health and Clinical Excellence - Advice

143. The widely used antimicrobial triclosan induces high levels of antibiotic tolerance <i>in vitro</i> and reduces antibiotic efficacy up to 100-fold <i>in vivo</i>. Full Text available with Trip Pro

The widely used antimicrobial triclosan induces high levels of antibiotic tolerance in vitro and reduces antibiotic efficacy up to 100-fold in vivo. The antimicrobial triclosan is used in a wide range of consumer products ranging from toothpaste, cleansers, socks, and baby toys. A bacteriostatic inhibitor of fatty acid synthesis, triclosan is extremely stable and accumulates in the environment. Approximately 75% of adults in the US have detectable levels of the compound (...) in their urine, with a sizeable fraction of individuals (>10%) having urine concentrations equal to or greater than the minimal inhibitory concentration for Escherichia coli and methicillin-resistant Staphylococcus aureus (MRSA). Previous work has identified connections between defects in fatty acid synthesis and accumulation of the alarmone guanosine tetraphosphate (ppGpp), which has been repeatedly associated with antibiotic tolerance and persistence. Based on these data, we hypothesized that triclosan

2019 Antimicrobial Agents and Chemotherapy

144. Antibiotic resistance is lower in Staphylococcus aureus isolated from antibiotic-free raw meat as compared to conventional raw meat. Full Text available with Trip Pro

Antibiotic resistance is lower in Staphylococcus aureus isolated from antibiotic-free raw meat as compared to conventional raw meat. The frequent use of antibiotics contributes to antibiotic resistance in bacteria, resulting in an increase in infections that are difficult to treat. Livestock are commonly administered antibiotics in their feed, but there is current interest in raising animals that are only administered antibiotics during active infections. Staphylococcus aureus (SA) is a common (...) pathogen of both humans and livestock raised for human consumption. SA has achieved high levels of antibiotic resistance, but the origins and locations of resistance selection are poorly understood. We determined the prevalence of SA and MRSA in conventional and antibiotic-free (AF) meat products, and also measured rates of antibiotic resistance in these isolates. We isolated SA from raw conventional turkey, chicken, beef, and pork samples and also from AF chicken and turkey samples. We found that SA

2018 PLoS ONE

145. Antibiotic susceptibility testing of Mycoplasma hyopneumoniae field isolates from Central Europe for fifteen antibiotics by microbroth dilution method. Full Text available with Trip Pro

performances of the animals. Antibiotic susceptibility testing of M. hyopneumoniae is time-consuming and complicated; therefore, it is not accomplished routinely. The aim of this study was to determine the in vitro susceptibility to 15 different antibiotics of M. hyopneumoniae isolates originating from Hungarian slaughterhouses and to examine single-nucleotide polymorphisms (SNPs) in genes affecting susceptibility to antimicrobials. Minimum inhibitory concentration (MIC) values of the examined antibiotics (...) Antibiotic susceptibility testing of Mycoplasma hyopneumoniae field isolates from Central Europe for fifteen antibiotics by microbroth dilution method. Mycoplasma hyopneumoniae infections are responsible for significant economic losses in the swine industry. Commercially available vaccines are not able to inhibit the colonisation of the respiratory tract by M. hyopneumoniae absolutely, therefore vaccination can be completed with antibiotic treatment to moderate clinical signs and improve

2018 PLoS ONE

146. Extended antibiotic treatment in salmon farms select multiresistant gut bacteria with a high prevalence of antibiotic resistance genes. Full Text available with Trip Pro

Extended antibiotic treatment in salmon farms select multiresistant gut bacteria with a high prevalence of antibiotic resistance genes. The high use of antibiotics for the treatment of bacterial diseases is one of the main problems in the mass production of animal protein. Salmon farming in Chile is a clear example of the above statement, where more than 5,500 tonnes of antibiotics have been used over the last 10 years. This has caused a great impact both at the production level (...) and on the environment; however, there are still few works in relation to it. In order to demonstrate the impact of the high use of antibiotics on fish gut microbiota, we have selected four salmon farms presenting a similar amount of fish of the Atlantic salmon species (Salmo salar), ranging from 4,500 to 6,000 tonnes. All of these farms used treatments with high doses of antibiotics. Thus, 15 healthy fish were selected and euthanised in order to isolate the bacteria resistant to the antibiotics oxytetracycline

2018 PLoS ONE

147. Antibacterial activity of antipsychotic agents, their association with lipid nanocapsules and its impact on the properties of the nanocarriers and on antibacterial activity. Full Text available with Trip Pro

Antibacterial activity of antipsychotic agents, their association with lipid nanocapsules and its impact on the properties of the nanocarriers and on antibacterial activity. Bacterial antibiotic resistance is an emerging public health problem worldwide; therefore, new therapeutic strategies are needed. Many studies have described antipsychotic compounds that present antibacterial activity. Hence, the aims of this study were to evaluate the in vitro antibacterial activity of antipsychotics (...) belonging to different chemical families, to assess the influence of their association with lipid nanocapsules (LNCs) on their antimicrobial activity as well as drug release and to study the uptake of LNCs by bacterial cells. Antibacterial activity was evaluated against Gram-positive Staphylococcus aureus and Gram negative Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae and Acinetobacter baumannii by minimum inhibitory concentration (MIC) assay, and the capability of killing tested

2018 PLoS ONE

148. Correction: Impact of extensive antibiotic treatment on faecal carriage of antibiotic-resistant enterobacteria in children in a low resistance prevalence setting. Full Text available with Trip Pro

Correction: Impact of extensive antibiotic treatment on faecal carriage of antibiotic-resistant enterobacteria in children in a low resistance prevalence setting. [This corrects the article DOI: 10.1371/journal.pone.0187618.].

2018 PLoS ONE

149. Correction: Antibiotic resistance rates and physician antibiotic prescription patterns of uncomplicated urinary tract infections in southern Chinese primary care. Full Text available with Trip Pro

Correction: Antibiotic resistance rates and physician antibiotic prescription patterns of uncomplicated urinary tract infections in southern Chinese primary care. [This corrects the article DOI: 10.1371/journal.pone.0177266.].

2018 PLoS ONE

150. Antibiotic resistance among bacterial conjunctival pathogens collected in the Antibiotic Resistance Monitoring in Ocular Microorganisms (ARMOR) surveillance study. Full Text available with Trip Pro

Antibiotic resistance among bacterial conjunctival pathogens collected in the Antibiotic Resistance Monitoring in Ocular Microorganisms (ARMOR) surveillance study. The Antibiotic Resistance Monitoring in Ocular Microorganisms (ARMOR) surveillance study evaluates in vitro antibiotic resistance among Staphylococcus aureus, coagulase-negative staphylococci (CoNS), Streptococcus pneumoniae, Pseudomonas aeruginosa, and Haemophilus influenzae isolates from ocular infections. Here we report resistance (...) rates and trends among conjunctival-sourced ocular isolates collected across the US from 2009 through 2016. A total of 1198 conjunctival isolates (483 S. aureus, 305 CoNS, 208 H. influenzae, 118 S. pneumoniae, and 84 P. aeruginosa) were collected from patients with presumed bacterial conjunctivitis from 57 sites across 40 states. A large proportion of staphylococci demonstrated resistance to oxacillin and azithromycin, while resistance was low against the majority of antibiotics tested for S

2018 PLoS ONE

151. Antibacterial activity and safety of commercial veterinary cationic steroid antibiotics and neutral superoxidized water. Full Text available with Trip Pro

Antibacterial activity and safety of commercial veterinary cationic steroid antibiotics and neutral superoxidized water. Antibiotic resistance of bacteria common to the ocular surface is an evolving problem. Thus, novel treatment options with new modes of action are required. We investigated the antibacterial activity and safety of three commercially available topical veterinary ophthalmic products (cationic steroid antibiotics, products A and B, and a neutral superoxidized water, product C (...) ) to determine their potential use as antimicrobial alternatives. The minimum inhibitory concentrations (MIC) of the three products were determined against 17 antibiotic resistant bacterial clinical isolates from the ocular surface. Using a standard cytotoxicity assay, the products at varying concentrations were evaluated with a corneal fibroblast cell line and a macrophage-like cell line to determine their potential toxic effect in vitro. The commercial ophthalmic solutions, ofloxacin 0.3%, tobramycin 0.3

2018 PLoS ONE

152. Superficial Bacterial Skin Infections - Guidelines for Prescribing Topical Antibiotics for impetigo and folliculitis

Superficial Bacterial Skin Infections - Guidelines for Prescribing Topical Antibiotics for impetigo and folliculitis Superficial Bacterial Skin Infections - Guidelines for Prescribing Topical Antibiotics for impetigo and folliculitis - medSask Home - College of Pharmacy and Nutrition - University of Saskatchewan Toggle Menu Search the U of S Search Superficial Bacterial Skin Infections - Guidelines for Prescribing Topical Antibiotics for impetigo and folliculitis The skin has an effective (...) itchy, papules and/or pustules at the base of the hair shaft. The causative agent is usually aureus . Furuncles or boils usually begin as folliculitis which spreads and forms a tender, red swelling with a central pustule. This may progress to carbuncles, an aggregate of furuncles which penetrates to deeper layers of skin and can lead to cellulitis, a diffuse inflammation of the skin. Furuncles may require systemic antibiotic treatment. For more information and photos, go to: Less severe form

2017 medSask

153. Inconclusive evidence on using antibiotic prophylaxis before dental procedures to prevent infective endocarditis

Inconclusive evidence on using antibiotic prophylaxis before dental procedures to prevent infective endocarditis Inconclusive evidence on using antibiotic prophylaxis before dental procedures to prevent infective endocarditis ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health for all. Together. Take (...) Inconclusive evidence on using antibiotic prophylaxis before dental procedures to prevent infective endocarditis Mohamed-Nur Abdallah, BDS, MSc, PhD . Overview Systematic Review Conclusion Despite the limited evidence and poor methodological quality of many included studies, antibiotic prophylaxis (AP) for patients at highest risk of developing infective endocarditis (IE) is a pragmatic and justified approach. However, postprocedural bacteremia may not be a good surrogate end point for IE. Critical Summary

2017 ADA Center for Evidence-Based Dentistry

154. How should antibiotics be dosed in obesity?

How should antibiotics be dosed in obesity? How should antibiotics be dosed in obesity? – SPS - Specialist Pharmacy Service – The first stop for professional medicines advice Menu · · ∙ ∙ Published 20th February 2018, updated 12th April 2018 The Q&A produced in 2013 has been updated and published on the Scottish Antimicrobial Prescribing Group (SAPG) website. A review of the evidence was carried out in 2016 using the same literature search strategy by the Association of Scottish Antimicrobial (...) Pharmacists and Healthcare Improvement Scotland. This Q&A summarises the available evidence for several classes of antibiotics. Obesity results in physiological changes that can affect the volume of distribution and the clearance of many antibiotics. The extent of these changes is variable and depends upon patient characteristics (e.g. degree of obesity, underlying organ function) and the chemical properties of the antibiotic. Antibiotic concentrations achieved with conventional dosages may therefore

2018 Specialist Pharmacy Services

155. XYDALBA (dalbavancin), antibiotic of the glycopeptide class

XYDALBA (dalbavancin), antibiotic of the glycopeptide class Haute Autorité de Santé - XYDALBA (dalbavancine), antibiotique de la classe des glycopeptides Développer la qualité dans le champ sanitaire, social et médico-social Recherche Évaluation & Recommandation La HAS Accréditation & Certification Outils, Guides & Méthodes Agenda Avis sur les Médicaments XYDALBA (dalbavancine), antibiotique de la classe des glycopeptides Substance active (DCI) dalbavancine (chlorhydrate de) INFECTIOLOGIE

2017 Haute Autorite de sante

156. Inconclusive evidence on using antibiotic prophylaxis before dental procedures to prevent infective endocarditis

Inconclusive evidence on using antibiotic prophylaxis before dental procedures to prevent infective endocarditis Inconclusive evidence on using antibiotic prophylaxis before dental procedures to prevent infective endocarditis ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health for all. Together. Take (...) Inconclusive evidence on using antibiotic prophylaxis before dental procedures to prevent infective endocarditis Mohamed-Nur Abdallah, BDS, MSc, PhD . Overview Systematic Review Conclusion Despite the limited evidence and poor methodological quality of many included studies, antibiotic prophylaxis (AP) for patients at highest risk of developing infective endocarditis (IE) is a pragmatic and justified approach. However, postprocedural bacteremia may not be a good surrogate end point for IE. Critical Summary

2017 ADA Center for Evidence-Based Dentistry

157. Inconclusive evidence on using antibiotic prophylaxis before dental procedures to prevent infective endocarditis

Inconclusive evidence on using antibiotic prophylaxis before dental procedures to prevent infective endocarditis Inconclusive evidence on using antibiotic prophylaxis before dental procedures to prevent infective endocarditis ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health for all. Together. Take (...) Inconclusive evidence on using antibiotic prophylaxis before dental procedures to prevent infective endocarditis Mohamed-Nur Abdallah, BDS, MSc, PhD . Overview Systematic Review Conclusion Despite the limited evidence and poor methodological quality of many included studies, antibiotic prophylaxis (AP) for patients at highest risk of developing infective endocarditis (IE) is a pragmatic and justified approach. However, postprocedural bacteremia may not be a good surrogate end point for IE. Critical Summary

2017 ADA Center for Evidence-Based Dentistry

158. Randomised controlled trial: Clinical failure is more common in young children with acute otitis media who receive a short course of antibiotics compared with standard duration Full Text available with Trip Pro

otitis media who receive a short course of antibiotics compared with standard duration Article Text Therapeutics/Prevention Randomised controlled trial Clinical failure is more common in young children with acute otitis media who receive a short course of antibiotics compared with standard duration Roderick P Venekamp 1 , Anne G M Schilder 2 Statistics from Altmetric.com Commentary on: Hoberman A , Paradise JL , Rockette HE , et al . Shortened antimicrobial treatment for acute otitis media in young (...) children . Context Acute otitis media (AOM) is a leading cause of doctor consultations and antibiotic prescriptions in young children. 1 Strategies to reduce antibiotic prescribing for AOM and thereby the emerging spread of antimicrobial resistance have focused on watchful waiting and delayed prescription, in particular in children over 2 years. 2 An alternative strategy to combat antimicrobial resistance is to reduce the duration of antibiotic treatment. So far, the evidence to support this strategy

2017 Evidence-Based Medicine

159. Cohort study: General practices that reduce antibiotic prescribing for self-limiting respiratory tract infections by 10% can expect to see one extra patient with pneumonia each year and one peritonsillar abscess each decade

Cohort study: General practices that reduce antibiotic prescribing for self-limiting respiratory tract infections by 10% can expect to see one extra patient with pneumonia each year and one peritonsillar abscess each decade General practices that reduce antibiotic prescribing for self-limiting respiratory tract infections by 10% can expect to see one extra patient with pneumonia each year and one peritonsillar abscess each decade | BMJ Evidence-Based Medicine We use cookies to improve our (...) * Password * your user name or password? You are here General practices that reduce antibiotic prescribing for self-limiting respiratory tract infections by 10% can expect to see one extra patient with pneumonia each year and one peritonsillar abscess each decade Article Text Therapeutics/Prevention Cohort study General practices that reduce antibiotic prescribing for self-limiting respiratory tract infections by 10% can expect to see one extra patient with pneumonia each year and one peritonsillar

2017 Evidence-Based Medicine

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