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121. Reducing antibiotic resistance

of antibiotic resistance. This year, we're urging people that it's time to take antibiotic resistance seriously. NPS MedicineWise has created a suite of resources you can download, print and share to raise awareness about antibiotic resistance and help preserve the power of antibiotics. Australian Prescriber: Antimicrobial use and resistance in Australia John Turnidge Aust Prescr 2017;40:2-31 Feb 2017 Managing the emergence and increasing resistance to antimicrobials in hospitals and the community has (...) become an urgent national and international problem. As part of a plan to tackle this, Australia is developing a coordinated national program to monitor antimicrobial use and resistance. Sometimes, parents need reassurance rather than antibiotics When their children are unwell, parents and carers often visit their GP for reassurance. They want to check their child doesn’t have a serious illness and have the opportunity to discuss what is worrying them about their child’s cold, cough, earache or sore

2017 National Prescribing Service Limited (Australia)

122. Antibiotic-impregnated bone cement for total hip arthroplasty and other orthopedic indications

. Controversy: Controversial issues related to the clinical use of ABCs include the safety and effectiveness of ABCs compared with other fixation methods, optimal antibiotic choice and dose, optimal cement preparation technique, costeffectiveness of ABCs, the appropriate use of ABC in a prophylactic setting, antimicrobial resistance, and patient selection (i.e., which patients might benefit the most from the treatment). Relevant Questions: Is ABC effective in preventing infection in primary hip or shoulder (...) Antibiotic-impregnated bone cement for total hip arthroplasty and other orthopedic indications Antibiotic-impregnated bone cement for total hip arthroplasty and other orthopedic indications Antibiotic-impregnated bone cement for total hip arthroplasty and other orthopedic indications HAYES, Inc Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation HAYES, Inc

2017 Health Technology Assessment (HTA) Database.

123. Oral antibiotics for secondary prophylaxis following two-stage revision surgery for prosthetic joint infection

Oral antibiotics for secondary prophylaxis following two-stage revision surgery for prosthetic joint infection Oral antibiotics for secondary prophylaxis following two-stage revision surgery for prosthetic joint infection Oral antibiotics for secondary prophylaxis following two-stage revision surgery for prosthetic joint infection Leas B, Mull, N. Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality (...) of this assessment has been made for the HTA database. Citation Leas B, Mull, N.. Oral antibiotics for secondary prophylaxis following two-stage revision surgery for prosthetic joint infection. Philadelphia: Center for Evidence-based Practice (CEP). 2017 Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Anti-Bacterial Agents; Communicable Diseases; Humans; Joint Diseases; Prosthesis-Related Infections; Reoperation; Secondary Prevention Language Published English Country of organisation

2017 Health Technology Assessment (HTA) Database.

124. Antibiotic-impregnated bone cement for knee arthroplasty

Antibiotic-impregnated bone cement for knee arthroplasty Antibiotic-impregnated bone cement for knee arthroplasty Antibiotic-impregnated bone cement for knee arthroplasty HAYES, Inc Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation HAYES, Inc. Antibiotic-impregnated bone cement for knee arthroplasty. Lansdale: HAYES, Inc. Directory Publication. 2017 Authors (...) ' conclusions Antibiotic bone cement (ABC) is a type of curable polymethylmethacrylate preparation created by adding various antibiotic medications to plain, nonmedicated bone cement. Most commonly, ABC is used to treat infected total joint prostheses as part of a revision arthroplasty, but its use as antibiotic prophylaxis in primary joint arthroplasty is increasing. Rationale: The usage of ABC at the arthroplasty site may be useful in maintaining a locally high level of antibiotic drug concentration

2017 Health Technology Assessment (HTA) Database.

125. Antibiotic therapy versus no antibiotic therapy for children aged two to 59 months with WHO-defined non-severe pneumonia and wheeze. (Abstract)

Antibiotic therapy versus no antibiotic therapy for children aged two to 59 months with WHO-defined non-severe pneumonia and wheeze. Worldwide, pneumonia is the leading cause of death among children under five years of age and accounts for approximately two million deaths annually. The World Health Organization (WHO) has developed case management guidelines based on simple clinical signs to help clinicians decide on the appropriate pneumonia treatment. Children and infants who exhibit fast (...) breathing (50 breaths per minute or more in infants two months to 12 months of age and 40 or more in children 12 months to five years of age) and cough are presumed to have non-severe pneumonia and the WHO recommends antibiotics. Implementation of these guidelines to identify and manage pneumonia at the community level has been shown to reduce acute respiratory infection (ARI)-related mortality by 36%, although apprehension exists regarding these results due to the questionable quality of evidence

2014 Cochrane

126. Antibiotics in hospitals: prophylaxis and antibiotic stewardship

Antibiotics in hospitals: prophylaxis and antibiotic stewardship Antibiotics in hospitals: prophylaxis and antibiotic stewardship Antibiotics in hospitals: prophylaxis and antibiotic stewardship Health Council of the Netherlands Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Health Council of the Netherlands. Antibiotics in hospitals: prophylaxis and antibiotic (...) stewardship. The Hague: Health Council of the Netherlands Gezondheidsraad (GR). 2015/12. 2015 Authors' conclusions In the summer of 2013, the Minister of Health, Welfare and Sport asked the Health Council for advice regarding the use of antibiotics in human health care. The Minister's questions focused on two main issues. Firstly, the Minister asked the Health Council to address aspects of antibiotic therapy that may contribute to antibiotic resistance, with selective decontamination mentioned

2015 Health Technology Assessment (HTA) Database.

127. Clostridium difficile infection: risk with broad-spectrum antibiotics

or based on the sensitivities of causative bacteria. The Department of Health Advisory Committee on Antimicrobial Resistance and Healthcare Associated Infection (ARHAI) recommends the Start smart - then focus approach. This recommends that, if immediate antibiotic treatment is necessary, the clinical diagnosis and continuing need for antibiotics should be reviewed within 48-72 hours. When antibiotics are considered necessary to treat common infections in primary care, Public Health England's guidance (...) on managing common infections recommends suitable options and advises that broad-spectrum antibiotics should be used only when narrow-spectrum antibiotics are ineffective. Appropriate use of antimicrobials is also important to reduce the serious threat of antimicrobial resistance. A cross-governmental UK 5 year antimicrobial resistance strategy was launched in 2013. Full text of introduction and current guidance. Evidence review This evidence review outlines 1 meta-analysis of hospital-associated C

2015 National Institute for Health and Clinical Excellence - Advice

128. Are there significant interactions between oral combined contraceptives and non-rifampin antibiotics?

Are there significant interactions between oral combined contraceptives and non-rifampin antibiotics? Q&A - Are there significant interactions between oral combined contraceptives and non-rifampin antibiotics? - Trip Database NEW! or use your Google+ account Liberating the literature ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere (...) in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Asked 23 Oct 2019 · , Physician assistant, BR Are there significant interactions between oral combined contraceptives and non-rifampin antibiotics? 1 Please log in to post a reply Your response: Reply Notes about answers If you

2019 Trip Community Q&A

129. How to adjust antibiotics dose in acute kidney injury (AKI) patient?

How to adjust antibiotics dose in acute kidney injury (AKI) patient? Q&A - How to adjust antibiotics dose in acute kidney injury (AKI) patient? - Trip Database NEW! or use your Google+ account Turning Research Into Practice ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search (...) numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Asked 21 Oct 2019 · , Pharmacist, SA How to adjust antibiotics dose in acute kidney injury (AKI) patient? 1 Please log in to post a reply Your response: Reply Notes about answers If you see something you feel is wrong, don’t criticise (that misses the point of Triple) courteously

2019 Trip Community Q&A

130. Evaluation of a clinical decision rule to guide antibiotic prescription in children with suspected lower respiratory tract infection in The Netherlands: A stepped-wedge cluster randomised trial Full Text available with Trip Pro

Evaluation of a clinical decision rule to guide antibiotic prescription in children with suspected lower respiratory tract infection in The Netherlands: A stepped-wedge cluster randomised trial Evaluation of a Clinical Decision Rule to Guide Antibiotic Prescription in Children With Suspected Lower Respiratory Tract Infection in The Netherlands: A Stepped-Wedge Cluster Randomised Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set (...) : Send at most: Send even when there aren't any new results Optional text in email: Save Cancel Create a file for external citation management software Create file Cancel Actions Cite Share Permalink Copy Page navigation PLoS Med Actions . 2020 Jan 31;17(1):e1003034. doi: 10.1371/journal.pmed.1003034. eCollection 2020 Jan. Evaluation of a Clinical Decision Rule to Guide Antibiotic Prescription in Children With Suspected Lower Respiratory Tract Infection in The Netherlands: A Stepped-Wedge Cluster

2020 EvidenceUpdates

131. Are Postoperative Intravenous Antibiotics Indicated After Laparoscopic Appendicectomy for Simple Appendicitis? A Prospective Double-blinded Randomized Controlled Trial

Are Postoperative Intravenous Antibiotics Indicated After Laparoscopic Appendicectomy for Simple Appendicitis? A Prospective Double-blinded Randomized Controlled Trial Are Postoperative Intravenous Antibiotics Indicated After Laparoscopic Appendicectomy for Simple Appendicitis? A Prospective Double-blinded Randomized Controlled Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy (...) to an existing collection Name your collection: Name must be less than 100 characters Choose a collection: Unable to load your collection due to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation Ann Surg Actions 2019 Dec 9 [Online ahead of print] Are Postoperative Intravenous Antibiotics Indicated After Laparoscopic Appendicectomy for Simple Appendicitis? A Prospective Double-blinded Randomized

2020 EvidenceUpdates

132. Early Childhood Antibiotic Treatment for Otitis Media and Other Respiratory Tract Infections Is Associated With Risk of Type 1 Diabetes: A Nationwide Register-Based Study With Sibling Analysis Full Text available with Trip Pro

Early Childhood Antibiotic Treatment for Otitis Media and Other Respiratory Tract Infections Is Associated With Risk of Type 1 Diabetes: A Nationwide Register-Based Study With Sibling Analysis Early Childhood Antibiotic Treatment for Otitis Media and Other Respiratory Tract Infections Is Associated With Risk of Type 1 Diabetes: A Nationwide Register-Based Study With Sibling Analysis - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set (...) : Send at most: Send even when there aren't any new results Optional text in email: Save Cancel Create a file for external citation management software Create file Cancel Actions Cite Share Permalink Copy Page navigation Diabetes Care Actions . 2020 Mar 4;dc191162. doi: 10.2337/dc19-1162. Online ahead of print. Early Childhood Antibiotic Treatment for Otitis Media and Other Respiratory Tract Infections Is Associated With Risk of Type 1 Diabetes: A Nationwide Register-Based Study With Sibling Analysis

2020 EvidenceUpdates

133. Prophylaxis of Wound Infections-antibiotics in Renal Donation (POWAR): A UK Multicentre Double blind Placebo Controlled Randomised Trial (Abstract)

Prophylaxis of Wound Infections-antibiotics in Renal Donation (POWAR): A UK Multicentre Double blind Placebo Controlled Randomised Trial Postoperative infection after hand-assisted laparoscopic donor nephrectomy (HALDN) confers significant morbidity to a healthy patient group. Current UK guidelines cite a lack of evidence for routine antibiotic prophylaxis. This trial assessed if a single preoperative antibiotic dose could reduce post HALDN infections.Eligible donors were randomly and blindly (...) allocated to preoperative single-dose intravenous co-amoxiclav or saline. The primary composite endpoint was clinical evidence of any postoperative infection at 30 days, including surgical site infection (SSI), urinary tract infection (UTI), and lower respiratory tract infection (LRTI).In all, 293 participants underwent HALDN (148 antibiotic arm and 145 placebo arm). Among them, 99% (291/293) completed follow-up. The total infection rate was 40.7% (59/145) in the placebo group and 23% (34 of 148

2020 EvidenceUpdates

134. Beta lactam antibiotic use with history of serum sickness with amoxicillin

Beta lactam antibiotic use with history of serum sickness with amoxicillin Beta lactam antibiotic use with history of serum sickness with amoxicillin ') Cookie Notice This site uses cookies. By continuing to browse this site, you are agreeing to our use of cookies. Review our for more details. OK Menu Search Main navigation Utility navigation / Search navigation Search Search AAAAI Breadcrumb navigation ▸ ▸ Beta lactam antibiotic use with history of serum sickness with amoxicillin | Beta lactam (...) antibiotic use with history of serum sickness with amoxicillin Q: 2/10/2020 A 28 year-old female with history of serum sickness like reaction to Amoxicillin with history of hives with Keflex at age 12. I would like to challenge her to Keflex as I do not believe the history is consistent with type I IgE mediated reaction and patient has idiopathic urticaria. Given her Type III Hypersensitivity reaction to Amoxicillin, should I worry about a serum sickness like reaction with other Beta lactams? A: Serum

2020 American Academy of Allergy, Asthma & Immunology - Ask the Expert

135. In utero exposure to systemic antibiotics vs reference penicillins was not linked to congenital malformations. (Abstract)

In utero exposure to systemic antibiotics vs reference penicillins was not linked to congenital malformations. Damkier P, Brønniche LM, Korch-Frandsen JF, Broe A. In utero exposure to antibiotics and risk of congenital malformations: a population-based study. Am J Obstet Gynecol. 2019;221:648.e1-648.e15. 31260651.

2020 Annals of Internal Medicine

136. Effect of C-Reactive Protein-Guided Antibiotic Treatment Duration, 7-Day Treatment, or 14-Day Treatment on 30-Day Clinical Failure Rate in Patients With Uncomplicated Gram-Negative Bacteremia: A Randomized Clinical Trial. (Abstract)

Effect of C-Reactive Protein-Guided Antibiotic Treatment Duration, 7-Day Treatment, or 14-Day Treatment on 30-Day Clinical Failure Rate in Patients With Uncomplicated Gram-Negative Bacteremia: A Randomized Clinical Trial. Antibiotic overuse drives antibiotic resistance. Gram-negative bacteremia is a common infection that results in substantial antibiotic use.To compare the clinical effectiveness of C-reactive protein (CRP)-guided, 7-day, and 14-day antibiotic durations 30, 60, and 90 days after (...) treatment initiation.Multicenter, noninferiority, point-of-care randomized clinical trial including adults hospitalized with gram-negative bacteremia conducted in 3 Swiss tertiary care hospitals between April 2017 and May 2019, with follow-up until August 2019. Patients and physicians were blinded between randomization and antibiotic discontinuation. Adults (aged ≥18 years) were eligible for randomization on day 5 (±1 d) of microbiologically efficacious therapy for fermenting, gram-negative bacteria

2020 JAMA

137. Clinicians prescribe antibiotics for childhood respiratory tract infection based on assessment, rather than parental expectation. (Abstract)

Clinicians prescribe antibiotics for childhood respiratory tract infection based on assessment, rather than parental expectation. The studyCabral C, Horwood J, Symonds J, et al. Understanding the influence of parent-clinician communication on antibiotic prescribing for children with respiratory tract infections in primary care: a qualitative observational study using a conversation analysis approach. BMC Fam Pract 2019;20:102.This project was funded by the NIHR School for Primary Care Research (...) Programme (project number SPCR204).To read the full NIHR Signal, go to: https://discover.dc.nihr.ac.uk/content/signal-000829/gps-assessment-not-parental-expectation-drives-antibiotic-prescribing.Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

2020 BMJ

138. Associations between macrolide antibiotics prescribing during pregnancy and adverse child outcomes in the UK: population based cohort study. Full Text available with Trip Pro

Associations between macrolide antibiotics prescribing during pregnancy and adverse child outcomes in the UK: population based cohort study. To assess the association between macrolide antibiotics prescribing during pregnancy and major malformations, cerebral palsy, epilepsy, attention deficit hyperactivity disorder, and autism spectrum disorder in children.Population based cohort study.The UK Clinical Practice Research Datalink.The study cohort included 104 605 children born from 1990 to 2016 (...) , 1.14 to 2.19, mainly hypospadias). Erythromycin in the first trimester was associated with an increased risk of any major malformation (27.39 v 17.65 per 1000, 1.50, 1.13 to 1.99). No statistically significant associations were found for other system specific malformations or for neurodevelopmental disorders. Findings were robust to sensitivity analyses.Prescribing macrolide antibiotics during the first trimester of pregnancy was associated with an increased risk of any major malformation

2020 BMJ

139. Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs Appendectomy for Uncomplicated Acute Appendicitis: A Secondary Analysis of a Randomized Clinical Trial

Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs Appendectomy for Uncomplicated Acute Appendicitis: A Secondary Analysis of a Randomized Clinical Trial Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs Appendectomy for Uncomplicated Acute Appendicitis: A Secondary Analysis of a Randomized Clinical Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features (...) in email: Save Cancel Create a file for external citation management software Create file Cancel Actions Cite Share Permalink Copy Page navigation JAMA Surg Actions . 2020 Feb 19;e196028. doi: 10.1001/jamasurg.2019.6028. Online ahead of print. Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs Appendectomy for Uncomplicated Acute Appendicitis: A Secondary Analysis of a Randomized Clinical Trial , , , , , , , , , , , , , Affiliations Expand Affiliations 1 Turku

2020 EvidenceUpdates

140. Antibiotic prophylaxis in primary and revision shoulder replacement: a systematic review Full Text available with Trip Pro

of hair, therefore a greater risk of P. acnes. in surface cultures. Patients were assessed at an average follow-up period of 20 months ranging from 9 weeks to 53 months. Conclusion: The optimal perioperative antimicrobial regimen is controversial. The clinical guidelines recommend the use of only one antibiotic as prophylaxis but considering the increase in the rates of antibiotic-resistant infections, the question arises whether antibiotic prophylaxis should be extended for adequate coverage (...) Antibiotic prophylaxis in primary and revision shoulder replacement: a systematic review Antibiotic prophylaxis in primary and revision shoulder replacement: a systematic review - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes of Health National Library of Medicine National Center for Biotechnology Information

2020 EvidenceUpdates

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