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61. Inhaled anti-pseudomonal antibiotics for long-term therapy in cystic fibrosis. (Abstract)

Inhaled anti-pseudomonal antibiotics for long-term therapy in cystic fibrosis. Inhaled antibiotics are commonly used to treat persistent airway infection with Pseudomonas aeruginosa that contributes to lung damage in people with cystic fibrosis. Current guidelines recommend inhaled tobramycin for individuals with cystic fibrosis and persistent Pseudomonas aeruginosa infection who are aged six years or older. The aim is to reduce bacterial load in the lungs so as to reduce inflammation (...) and deterioration of lung function. This is an update of a previously published review.To evaluate the effects long-term inhaled antibiotic therapy in people with cystic fibrosis on clinical outcomes (lung function, frequency of exacerbations and nutrition), quality of life and adverse events (including drug sensitivity reactions and survival).We searched the Cochrane Cystic Fibrosis Trials Register, compiled from electronic database searches and handsearching of journals and conference abstract books. We also

2018 Cochrane

62. Oral versus inhaled antibiotics for bronchiectasis. Full Text available with Trip Pro

Oral versus inhaled antibiotics for bronchiectasis. Bronchiectasis is a chronic inflammatory disease characterised by a recurrent cycle of respiratory bacterial infections associated with cough, sputum production and impaired quality of life. Antibiotics are the main therapeutic option for managing bronchiectasis exacerbations. Evidence suggests that inhaled antibiotics may be associated with more effective eradication of infective organisms and a lower risk of developing antibiotic resistance (...) when compared with orally administered antibiotics. However, it is currently unclear whether antibiotics are more effective when administered orally or by inhalation.To determine the comparative efficacy and safety of oral versus inhaled antibiotics in the treatment of adults and children with bronchiectasis.We identified studies through searches of the Cochrane Airways Group's Specialised Register (CAGR), which is maintained by the Information Specialist for the group. The Register contains trial

2018 Cochrane

63. Continuous versus intermittent antibiotics for bronchiectasis. Full Text available with Trip Pro

Continuous versus intermittent antibiotics for bronchiectasis. Bronchiectasis is a chronic airway disease characterised by a destructive cycle of recurrent airway infection, inflammation and tissue damage. Antibiotics are a main treatment for bronchiectasis. The aim of continuous therapy with prophylactic antibiotics is to suppress bacterial load, but bacteria may become resistant to the antibiotic, leading to a loss of effectiveness. On the other hand, intermittent prophylactic antibiotics (...) , given over a predefined duration and interval, may reduce antibiotic selection pressure and reduce or prevent the development of resistance. This systematic review aimed to evaluate the current evidence for studies comparing continuous versus intermittent administration of antibiotic treatment in bronchiectasis in terms of clinical efficacy, the emergence of resistance and serious adverse events.To evaluate the effectiveness of continuous versus intermittent antibiotics in the treatment of adults

2018 Cochrane

64. Probiotics for Antibiotic-Associated Diarrhea and Clostridium difficile Infection: A Review of Guidelines

Probiotics for Antibiotic-Associated Diarrhea and Clostridium difficile Infection: A Review of Guidelines Probiotics for Antibiotic-Associated Diarrhea and Clostridium difficile Infection: A Review of Guidelines | CADTH.ca Find the information you need Probiotics for Antibiotic-Associated Diarrhea and Clostridium difficile Infection: A Review of Guidelines Probiotics for Antibiotic-Associated Diarrhea and Clostridium difficile Infection: A Review of Guidelines Last updated: September 6, 2018 (...) Project Number: RC1013-000 Product Line: Research Type: Drug Report Type: Summary with Critical Appraisal Result type: Report Question What are the evidence-based guidelines regarding the use of probiotics for the prevention, management, and treatment of antibiotic-associated diarrhea and C. difficile infection? Key Message One guideline recommended the use of probiotics for treatment of antibiotic associated diarrhea (varying strength of recommendation depending on the product).Four guidelines did

2018 Canadian Agency for Drugs and Technologies in Health - Rapid Review

65. Probiotics for Antibiotic-Associated Diarrhea and Clostridium difficile Infection: A Review of Clinical Effectiveness

Probiotics for Antibiotic-Associated Diarrhea and Clostridium difficile Infection: A Review of Clinical Effectiveness Probiotics for Antibiotic-Associated Diarrhea and Clostridium difficile Infection: A Review of Clinical Effectiveness | CADTH.ca Find the information you need Probiotics for Antibiotic-Associated Diarrhea and Clostridium difficile Infection: A Review of Clinical Effectiveness Probiotics for Antibiotic-Associated Diarrhea and Clostridium difficile Infection: A Review of Clinical (...) Effectiveness Last updated: September 20, 2018 Project Number: RC1022-000 Product Line: Research Type: Drug Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of concurrent probiotic and antibiotic use for preventing antibiotic-associated diarrhea and C.difficile infection? What is the clinical effectiveness of probiotics for treating and managing antibiotic-associated diarrhea and C.difficile infection? Key Message No clear patterns have emerged

2018 Canadian Agency for Drugs and Technologies in Health - Rapid Review

66. Topical Antibiotics for the Treatment of Treatment-Resistant Impetigo: Clinical Effectiveness and Guidelines

Topical Antibiotics for the Treatment of Treatment-Resistant Impetigo: Clinical Effectiveness and Guidelines Topical Antibiotics for the Treatment of Treatment-Resistant Impetigo: Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Topical Antibiotics for the Treatment of Treatment-Resistant Impetigo: Clinical Effectiveness and Guidelines Topical Antibiotics for the Treatment of Treatment-Resistant Impetigo: Clinical Effectiveness and Guidelines Last updated: October (...) 4, 2018 Project Number: RA0968-000 Product Line: Research Type: Drug Report Type: Reference List Result type: Report Question What is the clinical evidence regarding the use of topical antibiotics for the treatment of treatment-resistant impetigo? What are the evidence-based guidelines regarding the treatment of treatment resistant impetigo? Key Message One systematic review with meta-analyses, one non-randomized study, and one evidence-based guideline were identified regarding the clinical

2018 Canadian Agency for Drugs and Technologies in Health - Rapid Review

67. Proposals for a more effective antibiotic policy in Belgium

(BAPCOC) 24 1.1.6 Difficult to obtain significant improvements 24 1.2 RESEARCH QUESTIONS & SCOPE 25 1.3 TERMINOLOGY 25 1.4 METHODOLOGY 26 1.5 STRUCTURE OF THE REPORT 26 2 ANTIBIOTIC USE AND ITS LINK WITH ANTIBACTERIAL RESISTANCE 27 2.1 WHAT IS ANTIMICROBIAL RESISTANCE? 27 2.1.1 Antibacterial resistance, a natural phenomenon 27 2.1.2 How do bacteria become resistant? 27 2.1.3 How does antibiotic resistance spread? 28 2.1.4 Multidrug resistant organisms 28 2.1.1 Resistance in community and healthcare (...) . This document is available on the website of the Belgian Health Care Knowledge Centre. KCE Report 311 Antibiotic policy in Belgium 1 ? TABLE OF CONTENTS LIST OF FIGURES 8 LIST OF TABLES 10 LIST OF ABBREVIATIONS 13 ? SCIENTIFIC REPORT 23 1 INTRODUCTION 23 1.1 SHORT DESCRIPTION OF THE PROBLEM 23 1.1.1 Antibiotic resistance 23 1.1.2 Antibiotic use in Belgium 24 1.1.3 The concept of prudent antimicrobial/antibiotic use 24 1.1.4 One Health approach 24 1.1.5 Belgian Antibiotic Policy Coordination Committee

2019 Belgian Health Care Knowledge Centre

68. Antibiotic Prophylaxis in Gynaecologic Procedures

Antibiotic Prophylaxis in Gynaecologic Procedures No. 275-Antibiotic Prophylaxis in Gynaecologic Procedures - Journal of Obstetrics and Gynaecology Canada Email/Username: Password: Remember me Search Terms Search within Search Volume 40, Issue 10, Pages e723–e733 No. 275-Antibiotic Prophylaxis in Gynaecologic Procedures x Nancy Van Eyk , MD Halifax, NS x Julie van Schalkwyk , MD Vancouver, BC No. 275, April 2012 (Reaffirmed October 2018) DOI: To view the full text, please login as a subscribed (...) user or . Click to view the full text on ScienceDirect. Abstract Objective To review the evidence and provide recommendations on antibiotic prophylaxis for gynaecologic procedures. Outcomes Outcomes evaluated include need and effectiveness of antibiotics to prevent infections in gynaecologic procedures. Evidence Medline and The Cochrane Library were searched for articles published between January 1978 and January 2011 on the topic of antibiotic prophylaxis in gynaecologic procedures. Results were

2018 Society of Obstetricians and Gynaecologists of Canada

69. Procalcitonin and Antibiotics for Lower Respiratory Tract Infections

Procalcitonin and Antibiotics for Lower Respiratory Tract Infections Procalcitonin and Antiobiotics for Lower Respiratory Tract Infections | Emergency Medicine | Washington University in St. Louis Open Menu Back Close Menu Search for: Loading... Welcome Sections Education Fellowships Alumni Research ECRC Journal Club Events Lewis Health Policy Symposia Jermyn Lectures Open Search Article 2: Schuetz P, Wirz Y, Sager R, et al. Procalcitonin to initiate or discontinue antibiotics in acute (...) respiratory tract infections. Cochrane Database Syst Rev. 2017 Oct 12;10:CD007498. Article 3: Huang DT, Yealy DM, Filbin MR, et al: ProACT Investigators. Procalcitonin-Guided Use of Antibiotics for Lower Respiratory Tract Infection. N. Engl J Med. 2018 Jul 19;379(3): 236-249 Article 4: Walsh EE, Swinburne AJ, Becker KL, et al. Can serum procalcitonin levels help interpret indeterminate chest radiographs in patients hospitalized with acute respiratory illness? J Hosp Med. 2013 Feb;8(2): 61-7 Bottom Line

2018 Washington University Emergency Medicine Journal Club

70. C-reactive protein point-of-care testing (CRP POCT) to guide antibiotic prescribing in primary care settings for acute respiratory tract infections. EUnetHTA-Report . HTA-Projektbericht 116.

C-reactive protein point-of-care testing (CRP POCT) to guide antibiotic prescribing in primary care settings for acute respiratory tract infections. EUnetHTA-Report . HTA-Projektbericht 116. C-reactive protein point-of-care testing (CRP POCT) to guide antibiotic prescribing in primary care settings for acute respiratory tract infections. EUnetHTA-Report - Repository of AIHTA GmbH English | Browse - - - C-reactive protein point-of-care testing (CRP POCT) to guide antibiotic prescribing (...) in primary care settings for acute respiratory tract infections. EUnetHTA-Report Harrington, P. and Lucey, D. and O’Brien, K. and Jordan, K. and Moran, P. and Marshall, L. and Wilbacher, I. and Gloeckner, L. (2019): C-reactive protein point-of-care testing (CRP POCT) to guide antibiotic prescribing in primary care settings for acute respiratory tract infections. EUnetHTA-Report . HTA-Projektbericht 116. Preview - Sie müssen einen PDF-Viewer auf Ihrem PC installiert haben wie z. B. , oder 3MB Abstract

2019 Austrian Institute of Health Technology Assessment

71. Antibiotic Prophylaxis for Dental Patients at Risk for Infection

of bacterial endocarditis: Recommendations by the American Heart Association. JAMA 1997;227(22):1794-801. 11. Centers for Disease Control and Prevention. Antibiotic/ Antimicrobial resistance. About antimicrobial resistance: A brief overview. Available at: “https://www.cdc.gov/drug resistance/about.html”. Accessed March 26, 2019. Archived by WebCite ® at: “http://www.webcitation.org/ 779R5H5EJ”) 12. Glenny AM, Oliver R, Roberts GJ, Hooper L, Worthington HV. Antibiotics for the prophylaxis of bacterial (...) Antibiotic Prophylaxis for Dental Patients at Risk for Infection 416 THE REFERENCE MANUAL OF PEDIATRIC DENTISTRY BEST PRACTICES: ANTIBIOTIC PROPHYLAXIS Purpose The American Academy of Pediatric Dentistry ( AAPD) recog- nizes that numerous medical conditions predispose patients to bacteremia-induced infections. Because it is not possible to predict when a susceptible patient will develop an infection, prophylactic antibiotics are recommended when these patients undergo procedures

2019 American Academy of Pediatric Dentistry

72. Use of Antibiotic Therapy for Pediatric Dental Patients

/MEDLINE database using the terms: antibiotic therapy, antibacterial agents, antimicrobial agents, dental trauma, oral wound management, orofacial infections, periodontal disease, viral disease, and oral contraception; fields: all; limits: within the last 10 years, humans, English, clinical trials, birth through age 18. Three hundred forty-three articles matched these criteria. Papers for review were chosen from this search and from hand searching. When data did not appear sufficient or were (...) derivatives remain the empirical choice for odontogenic infections; however, consideration of additional adjunctive antimicrobial therapy (i.e., metronidazole) can be given where there is anaerobic bacterial involvement. 13,16 Cephalosporins could be considered as an alternative choice for odontogenic infections. 16 Dental trauma Systemic antibiotics have been recommended as adjunctive therapy for avulsed permanent incisors with an open or closed apex. 17,18 Tetracycline (doxycycline twice daily for seven

2019 American Academy of Pediatric Dentistry

73. Probiotics to Prevent Antibiotic Associated Diarrhea in Children

Probiotics to Prevent Antibiotic Associated Diarrhea in Children Emergency Medicine > Journal Club > Archive > November 2017 Toggle navigation November 2017 Probiotics to Prevent Antibiotic Associated Diarrhea in Children Vignette You are working in the SLCH ED. An 18-month-old unvaccinated patient has right ear pain and fever for 4 days, along with a runny nose and irritability. You look in her ear and see a bulging red eardrum. You are a superior clinician so you pull out your insufflator (...) and find that the eardrum has limited mobility, especially compared to the other side. with a diagnosis of acute otitis media in hand, you decide to prescribe high-dose amoxicillin for the child, based on the . However, as you start to explain this to the parents, they sound very hesitant because they have had other children who "always" get diarrhea when given antibiotics. They also recently had an elderly relative who was ill due to C. diff and they are scared to give their daughter antibiotics

2018 Washington University Emergency Medicine Journal Club

74. Do antibiotics improve outcomes for patients hospitalized with COPD exacerbations?

Do antibiotics improve outcomes for patients hospitalized with COPD exacerbations? Do antibiotics improve outcomes for patients hospitalized with COPD exacerbations? Toggle navigation Shared more. Cited more. Safe forever. Toggle navigation View Item JavaScript is disabled for your browser. Some features of this site may not work without it. Search MOspace This Collection Browse Statistics Do antibiotics improve outcomes for patients hospitalized with COPD exacerbations? View/ Open Date 2012-09 (...) Format Metadata Abstract Antibiotic use reduced mortality and treatment failure in patients hospitalized with acute exacerbations of chronic obstructive pulmonary disease (COPD) (strength of recommendation [SOR]: A, systematic reviews of randomized controlled trials [RCTs]). Giving antibiotics early to hospitalized patients decreased the need for later ventilation and readmission within 30 days for exacerbation of COPD (SOR: B, a retrospective cohort study). URI Citation Journal of Family Practice

2018 Clinical Inquiries

75. Is the use of chlorhexidine contributing to increased resistance to chlorhexidine and/or antibiotics?

’ defined by using the clinical breakpoints for resistance as specified by the European Committee on Antimicrobial Susceptibility testing (EUCAST) or the Clinical and Laboratory Standards Institute (CSLI). 2. Increase in the incidence (rate) of antibiotic-resistant strains of bacteria established through the use of chlorhexidine identifying dosage form, exposure and specific population and / or setting. Antibiotic-resistant strain of bacteria through the use of chlorhexidine to be recorded. 3. Increases (...) to chlorhexidine in a specific population and / or setting. To address the question ‘Does exposure (different dosages, duration of use, and stratification of exposure) to any form of chlorhexidine increases the incidence and/or prevalence of antibiotic- resistant strains of bacteria in any person within different healthcare settings? ’ the outcomes included: ? ‘Resistance against antibiotics’ defined by using the clinical breakpoints for resistance as specified by the European Committee on Antimicrobial

2018 National Health and Medical Research Council

76. Antibiotics: repeated treatments before the age of two could be a factor in obesity

Antibiotics: repeated treatments before the age of two could be a factor in obesity Prescrire IN ENGLISH - Spotlight ''Antibiotics: repeated treatments before the age of two could be a factor in obesity'', 1 June 2018 {1} {1} {1} | | > > > Antibiotics: repeated treatments before the age of two could be a factor in obesity Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |   |   |   |   |   |   |  (...)  |  Spotlight Antibiotics: repeated treatments before the age of two could be a factor in obesity Antibiotics disrupt the intestinal flora (intestinal microbiota) and could be a factor in weight gain. Prescription of antibiotics for children should not be automatic but should be evaluated on a case-by-case basis. Overweight and obesity are the result of an imbalance between energy intake and energy expenditure and can be associated with various known genetic, hormone, environmental

2018 Prescrire

77. Systemic Antibiotics for the Treatment of Skin and Soft Tissue Abscesses: A Systematic Review and Meta-Analysis

Systemic Antibiotics for the Treatment of Skin and Soft Tissue Abscesses: A Systematic Review and Meta-Analysis Systemic Antibiotics for the Treatment of Skin and Soft Tissue Abscesses: A Systematic Review and Meta-Analysis Michael Gottlieb, MD*; Joshua M. DeMott, PharmD, MSc; Marilyn Hallock, MD, MS; Gary D. Peksa, PharmD *Corresponding Author. E-mail: michaelgottliebmd@gmail.com, Twitter: @MGottliebMD. Study objective: The addition of antibiotics to standard incision and drainage (...) is controversial, with earlier studies demonstrating no signi?cant bene?t. However, 2 large, multicenter trials have recently been published that have challenged the previous literature. The goal of this review was to determine whether systemic antibiotics for abscesses after incision and drainage improve cure rates. Methods: PubMed, the Cumulative Index of Nursing and Allied Health Literature, Scopus, the Cochrane Database of Systematic Reviews, the Cochrane Central Register of Controlled Trials

2018 Annals of Emergency Medicine Systematic Review Snapshots

78. Is Antibiotic Therapy Helpful for Preventing Infection After Acute Stroke? (SRS therapy)

Is Antibiotic Therapy Helpful for Preventing Infection After Acute Stroke? (SRS therapy) Is Antibiotic Therapy Helpful for Preventing Infection After Acute Stroke? TAKE-HOME MESSAGE In patients with acute ischemic or hemorrhagic stroke, prophylactic antibiotics reduce the overall infection rate, but do not reduce the risk of pneumonia, death or dependency. EBEM Commentators Latha Ganti, MD, MBA Department of Clinical Sciences University of Central Florida College of Medicine Orlando, FL Bryan (...) Sleigh, MD Department of Emergency Medicine Mercer University School of Medicine Macon, GA Jestin N. Carlson, MD, MS, and Alan Jones, MD, serve as editors of the SRS series. Editor’s Note: This is a clinical synopsis, a regular feature of the Annals’ Systematic Review Snapshot (SRS) series. The source for this systematic review snapshot is: Vermeij JD, Westendorp WF, Dippel DWJ, et al. Antibiotic therapy for preventing infections in people with acute stroke. Cochrane Database Syst Rev. 2018;1

2018 Annals of Emergency Medicine Systematic Review Snapshots

79. Antibiotics

. But if you still have questions please contact us via jon.brassey@tripdatabase.com Antibiotics Antibiotics also referred to as antibacterial are a type of medicine that prevents the growth of bacteria. As such they are used to treat infections caused by bacteria. They kill or prevents bacteria from spreading. Antibiotics are vital in modern day medicine; they are among the most frequently prescribed drug. There are over a 100 types of antibiotics, the main types and most commonly prescribed (...) Antibiotics Top results for antibiotics - Trip Database or use your Google+ account Find evidence fast ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4

2018 Trip Latest and Greatest

80. The Community IntraVenous Antibiotic Study (CIVAS): a mixed-methods evaluation of patient preferences for and cost-effectiveness of different service models for delivering outpatient parenteral antimicrobial therapy

The Community IntraVenous Antibiotic Study (CIVAS): a mixed-methods evaluation of patient preferences for and cost-effectiveness of different service models for delivering outpatient parenteral antimicrobial therapy The Community IntraVenous Antibiotic Study (CIVAS): a mixed-methods evaluation of patient preferences for and cost-effectiveness of different service models for delivering outpatient parenteral antimicrobial therapy The Community IntraVenous Antibiotic Study (CIVAS): a mixed-methods (...) . Citation Minton J, Czoski Murray C, Meads D, Hess S, Vargas-Palacios A, Mitchell E, Wright J, Hulme C, Raynor D K, Gregson A, Stanley P, McLintock K, Vincent R & Twiddy M. The Community IntraVenous Antibiotic Study (CIVAS): a mixed-methods evaluation of patient preferences for and cost-effectiveness of different service models for delivering outpatient parenteral antimicrobial therapy. Health Services and Delivery Research 2017; 5(6) Authors' objectives Outpatient parenteral antimicrobial therapy (OPAT

2017 Health Technology Assessment (HTA) Database.

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