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61. Prophylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD). (Full text)

Prophylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD). There has been renewal of interest in the use of prophylactic antibiotics to reduce the frequency of exacerbations and improve quality of life in chronic obstructive pulmonary disease (COPD).To determine whether or not regular (continuous, intermittent or pulsed) treatment of COPD patients with prophylactic antibiotics reduces exacerbations or affects quality of life.We searched the Cochrane Airways Group Trials (...) Register and bibliographies of relevant studies. The latest literature search was performed on 27 July 2018.Randomised controlled trials (RCTs) that compared prophylactic antibiotics with placebo in patients with COPD.We used the standard Cochrane methods. Two independent review authors selected studies for inclusion, extracted data, and assessed risk of bias. We resolved discrepancies by involving a third review author.We included 14 studies involving 3932 participants in this review. We identified

2018 Cochrane PubMed abstract

62. Antibiotics for exacerbations of chronic obstructive pulmonary disease. (Full text)

Antibiotics for exacerbations of chronic obstructive pulmonary disease. Many patients with an exacerbation of chronic obstructive pulmonary disease (COPD) are treated with antibiotics. However, the value of antibiotics remains uncertain, as systematic reviews and clinical trials have shown conflicting results.To assess effects of antibiotics on treatment failure as observed between seven days and one month after treatment initiation (primary outcome) for management of acute COPD exacerbations (...) , as well as their effects on other patient-important outcomes (mortality, adverse events, length of hospital stay, time to next exacerbation).We searched the Cochrane Central Register of Controlled Trials (CENTRAL), in the Cochrane Library, MEDLINE, Embase, and other electronically available databases up to 26 September 2018.We sought to find randomised controlled trials (RCTs) including people with acute COPD exacerbations comparing antibiotic therapy and placebo and providing follow-up of at least

2018 Cochrane PubMed abstract

63. Antibiotics for treating scrub typhus. (Full text)

Antibiotics for treating scrub typhus. Scrub typhus, an important cause of acute fever in Asia, is caused by Orientia tsutsugamushi, an obligate intracellular bacterium. Antibiotics currently used to treat scrub typhus include tetracyclines, chloramphenicol, macrolides, and rifampicin.To assess and compare the effects of different antibiotic regimens for treatment of scrub typhus.We searched the following databases up to 8 January 2018: the Cochrane Infectious Diseases Group specialized trials (...) register; CENTRAL, in the Cochrane Library (2018, Issue 1); MEDLINE; Embase; LILACS; and the metaRegister of Controlled Trials (mRCT). We checked references and contacted study authors for additional data. We applied no language or date restrictions.Randomized controlled trials (RCTs) or quasi-RCTs comparing antibiotic regimens in people with the diagnosis of scrub typhus based on clinical symptoms and compatible laboratory tests (excluding the Weil-Felix test).For this update, two review authors re

2018 Cochrane PubMed abstract

64. Head-to-head trials of antibiotics for bronchiectasis. (Full text)

Head-to-head trials of antibiotics for bronchiectasis. The diagnosis of bronchiectasis is defined by abnormal dilation of the airways related to a pathological mechanism of progressive airway destruction that is due to a 'vicious cycle' of recurrent bacterial infection, inflammatory mediator release, airway damage, and subsequent further infection. Antibiotics are the main treatment option for reducing bacterial burden in people with exacerbations of bronchiectasis and for longer-term (...) eradication, but their use is tempered against potential adverse effects and concerns regarding antibiotic resistance. The comparative effectiveness, cost-effectiveness, and safety of different antibiotics have been highlighted as important issues, but currently little evidence is available to help resolve uncertainty on these questions.To evaluate the comparative effects of different antibiotics in the treatment of adults and children with bronchiectasis.We identified randomised controlled trials (RCTs

2018 Cochrane PubMed abstract

65. Antibiotics for prolonged wet cough in children. (Full text)

Antibiotics for prolonged wet cough in children. Cough is a frequent symptom presenting to doctors. The most common cause of childhood chronic (greater than fours weeks' duration) wet cough is protracted bacterial bronchitis (PBB) in some settings, although other more serious causes can also present this way. Timely and effective management of chronic wet or productive cough improves quality of life and clinical outcomes. Current international guidelines suggest a course of antibiotics (...) is the first treatment of choice in the absence of signs or symptoms specific to an alternative diagnosis. This review sought to clarify the current evidence to support this recommendation.To determine the efficacy of antibiotics in treating children with prolonged wet cough (excluding children with bronchiectasis or other known underlying respiratory illness) and to assess risk of harm due to adverse events.We undertook an updated search (from 2008 onwards) using the Cochrane Airways Group Specialised

2018 Cochrane PubMed abstract

66. Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults. (Full text)

Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults. Dental pain can have a detrimental effect on quality of life. Symptomatic apical periodontitis and acute apical abscess are common causes of dental pain and arise from an inflamed or necrotic dental pulp, or infection of the pulpless root canal system. Clinical guidelines recommend that the first-line treatment for teeth with these conditions should be removal of the source of inflammation or infection (...) by local, operative measures, and that systemic antibiotics are currently only recommended for situations where there is evidence of spreading infection (cellulitis, lymph node involvement, diffuse swelling) or systemic involvement (fever, malaise). Despite this, there is evidence that dentists frequently prescribe antibiotics in the absence of these signs. There is concern that this could contribute to the development of antibiotic-resistant bacterial colonies within both the individual

2018 Cochrane PubMed abstract

67. Dual antibiotics for bronchiectasis. (Full text)

Dual antibiotics for bronchiectasis. Bronchiectasis is a chronic respiratory disease characterised by abnormal and irreversible dilatation of the smaller airways and associated with a mortality rate greater than twice that of the general population. Antibiotics serve as front-line therapy for managing bacterial load, but their use is weighed against the development of antibiotic resistance. Dual antibiotic therapy has the potential to suppress infection from multiple strains of bacteria (...) , leading to more successful treatment of exacerbations, reduced symptoms, and improved quality of life. Further evidence is required on the efficacy of dual antibiotics in terms of management of exacerbations and extent of antibiotic resistance.To evaluate the effects of dual antibiotics in the treatment of adults and children with bronchiectasis.We identified studies from the Cochrane Airways Group Specialised Register (CAGR), which includes the Cochrane Central Register of Controlled Trials (CENTRAL

2018 Cochrane PubMed abstract

68. Systematic review of stability data pertaining to selected antibiotics used for extended infusions in outpatient parenteral antimicrobial therapy (OPAT) at standard room temperature and in warmer climates. (Abstract)

Systematic review of stability data pertaining to selected antibiotics used for extended infusions in outpatient parenteral antimicrobial therapy (OPAT) at standard room temperature and in warmer climates. To determine if there are sufficient stability data to confirm appropriate prescribing of antibiotics commonly used in outpatient parenteral antimicrobial therapy (OPAT) in warmer climates.Four databases were systematically searched using the terms 'beta-lactams', or 'antibiotics', or 'anti (...) be further grey literature supporting the stability of some of the drugs mentioned.There are insufficient stability data of antibiotic use in warmer climates. Studies to verify the stability and appropriate use of many antibiotics used in OPAT at standard room temperature and in warmer climates are urgently required. Several drugs in current use in the OPAT settings are lacking stability data.Further research in this field is needed to develop structured evidence-based guidelines. Results of this review

2020 European journal of hospital pharmacy : science and practice

69. Procalcitonin and Antibiotics for Lower Respiratory Tract Infections

Procalcitonin and Antibiotics for Lower Respiratory Tract Infections Procalcitonin and Antiobiotics for Lower Respiratory Tract Infections | Emergency Medicine | Washington University in St. Louis Open Menu Back Close Menu Search for: Loading... Welcome Sections Education Fellowships Alumni Research ECRC Journal Club Events Lewis Health Policy Symposia Jermyn Lectures Open Search Article 2: Schuetz P, Wirz Y, Sager R, et al. Procalcitonin to initiate or discontinue antibiotics in acute (...) respiratory tract infections. Cochrane Database Syst Rev. 2017 Oct 12;10:CD007498. Article 3: Huang DT, Yealy DM, Filbin MR, et al: ProACT Investigators. Procalcitonin-Guided Use of Antibiotics for Lower Respiratory Tract Infection. N. Engl J Med. 2018 Jul 19;379(3): 236-249 Article 4: Walsh EE, Swinburne AJ, Becker KL, et al. Can serum procalcitonin levels help interpret indeterminate chest radiographs in patients hospitalized with acute respiratory illness? J Hosp Med. 2013 Feb;8(2): 61-7 Bottom Line

2018 Washington University Emergency Medicine Journal Club

70. Probiotics for Antibiotic-Associated Diarrhea and Clostridium difficile Infection: A Review of Guidelines

Probiotics for Antibiotic-Associated Diarrhea and Clostridium difficile Infection: A Review of Guidelines Probiotics for Antibiotic-Associated Diarrhea and Clostridium difficile Infection: A Review of Guidelines | CADTH.ca Find the information you need Probiotics for Antibiotic-Associated Diarrhea and Clostridium difficile Infection: A Review of Guidelines Probiotics for Antibiotic-Associated Diarrhea and Clostridium difficile Infection: A Review of Guidelines Last updated: September 6, 2018 (...) Project Number: RC1013-000 Product Line: Research Type: Drug Report Type: Summary with Critical Appraisal Result type: Report Question What are the evidence-based guidelines regarding the use of probiotics for the prevention, management, and treatment of antibiotic-associated diarrhea and C. difficile infection? Key Message One guideline recommended the use of probiotics for treatment of antibiotic associated diarrhea (varying strength of recommendation depending on the product).Four guidelines did

2018 Canadian Agency for Drugs and Technologies in Health - Rapid Review

71. Probiotics for Antibiotic-Associated Diarrhea and Clostridium difficile Infection: A Review of Clinical Effectiveness

Probiotics for Antibiotic-Associated Diarrhea and Clostridium difficile Infection: A Review of Clinical Effectiveness Probiotics for Antibiotic-Associated Diarrhea and Clostridium difficile Infection: A Review of Clinical Effectiveness | CADTH.ca Find the information you need Probiotics for Antibiotic-Associated Diarrhea and Clostridium difficile Infection: A Review of Clinical Effectiveness Probiotics for Antibiotic-Associated Diarrhea and Clostridium difficile Infection: A Review of Clinical (...) Effectiveness Last updated: September 20, 2018 Project Number: RC1022-000 Product Line: Research Type: Drug Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of concurrent probiotic and antibiotic use for preventing antibiotic-associated diarrhea and C.difficile infection? What is the clinical effectiveness of probiotics for treating and managing antibiotic-associated diarrhea and C.difficile infection? Key Message No clear patterns have emerged

2018 Canadian Agency for Drugs and Technologies in Health - Rapid Review

72. Topical Antibiotics for the Treatment of Treatment-Resistant Impetigo: Clinical Effectiveness and Guidelines

Topical Antibiotics for the Treatment of Treatment-Resistant Impetigo: Clinical Effectiveness and Guidelines Topical Antibiotics for the Treatment of Treatment-Resistant Impetigo: Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Topical Antibiotics for the Treatment of Treatment-Resistant Impetigo: Clinical Effectiveness and Guidelines Topical Antibiotics for the Treatment of Treatment-Resistant Impetigo: Clinical Effectiveness and Guidelines Last updated: October (...) 4, 2018 Project Number: RA0968-000 Product Line: Research Type: Drug Report Type: Reference List Result type: Report Question What is the clinical evidence regarding the use of topical antibiotics for the treatment of treatment-resistant impetigo? What are the evidence-based guidelines regarding the treatment of treatment resistant impetigo? Key Message One systematic review with meta-analyses, one non-randomized study, and one evidence-based guideline were identified regarding the clinical

2018 Canadian Agency for Drugs and Technologies in Health - Rapid Review

73. Antibiotic Prophylaxis in Gynaecologic Procedures

Antibiotic Prophylaxis in Gynaecologic Procedures No. 275-Antibiotic Prophylaxis in Gynaecologic Procedures - Journal of Obstetrics and Gynaecology Canada Email/Username: Password: Remember me Search Terms Search within Search Volume 40, Issue 10, Pages e723–e733 No. 275-Antibiotic Prophylaxis in Gynaecologic Procedures x Nancy Van Eyk , MD Halifax, NS x Julie van Schalkwyk , MD Vancouver, BC No. 275, April 2012 (Reaffirmed October 2018) DOI: To view the full text, please login as a subscribed (...) user or . Click to view the full text on ScienceDirect. Abstract Objective To review the evidence and provide recommendations on antibiotic prophylaxis for gynaecologic procedures. Outcomes Outcomes evaluated include need and effectiveness of antibiotics to prevent infections in gynaecologic procedures. Evidence Medline and The Cochrane Library were searched for articles published between January 1978 and January 2011 on the topic of antibiotic prophylaxis in gynaecologic procedures. Results were

2018 Society of Obstetricians and Gynaecologists of Canada

74. Antibiotics

. But if you still have questions please contact us via jon.brassey@tripdatabase.com Antibiotics Antibiotics also referred to as antibacterial are a type of medicine that prevents the growth of bacteria. As such they are used to treat infections caused by bacteria. They kill or prevents bacteria from spreading. Antibiotics are vital in modern day medicine; they are among the most frequently prescribed drug. There are over a 100 types of antibiotics, the main types and most commonly prescribed (...) Antibiotics Top results for antibiotics - Trip Database or use your Google+ account Find evidence fast ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4

2018 Trip Latest and Greatest

75. Is the use of chlorhexidine contributing to increased resistance to chlorhexidine and/or antibiotics?

’ defined by using the clinical breakpoints for resistance as specified by the European Committee on Antimicrobial Susceptibility testing (EUCAST) or the Clinical and Laboratory Standards Institute (CSLI). 2. Increase in the incidence (rate) of antibiotic-resistant strains of bacteria established through the use of chlorhexidine identifying dosage form, exposure and specific population and / or setting. Antibiotic-resistant strain of bacteria through the use of chlorhexidine to be recorded. 3. Increases (...) to chlorhexidine in a specific population and / or setting. To address the question ‘Does exposure (different dosages, duration of use, and stratification of exposure) to any form of chlorhexidine increases the incidence and/or prevalence of antibiotic- resistant strains of bacteria in any person within different healthcare settings? ’ the outcomes included: ? ‘Resistance against antibiotics’ defined by using the clinical breakpoints for resistance as specified by the European Committee on Antimicrobial

2018 National Health and Medical Research Council

77. Antibiotics for pediatric outpatients with community-acquired pneumonia

Antibiotics for pediatric outpatients with community-acquired pneumonia

2017 DynaMed Plus

78. Antibiotics for pediatric inpatients with community-acquired pneumonia

Antibiotics for pediatric inpatients with community-acquired pneumonia

2017 DynaMed Plus

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