How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

43,016 results for

antibiotic resistance

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

21. Impact of extensive antibiotic treatment on faecal carriage of antibiotic-resistant enterobacteria in children in a low resistance prevalence setting. Full Text available with Trip Pro

with cancer compared to the healthy children, not even at the end of the study when the children with cancer had been treated with repeated courses of broad-spectrum antibiotics. Children with cancer were mainly treated with intravenous antibiotics, while the CF group mainly received peroral treatment. Our observations indicate that the mode of administration of antibiotics and the general level of antimicrobial resistance in the community may have an impact on emergence of resistance in intestinal (...) Impact of extensive antibiotic treatment on faecal carriage of antibiotic-resistant enterobacteria in children in a low resistance prevalence setting. We prospectively studied the consequences of extensive antibiotic treatment on faecal carriage of antibiotic-resistant enterobacteria in a cohort of children with cystic fibrosis (CF) and a cohort of children with cancer compared to healthy children with no or low antibiotic exposure. The study was conducted in Norway in a low resistance

2017 PLoS ONE

22. The magnitude of antibiotic resistance to Helicobacter pylori in Africa and identified mutations which confer resistance to antibiotics: systematic review and meta-analysis. Full Text available with Trip Pro

The magnitude of antibiotic resistance to Helicobacter pylori in Africa and identified mutations which confer resistance to antibiotics: systematic review and meta-analysis. Worldwide Helicobacter pylori (H.pylori) treatment is of great challenge due to increased antibiotic resistance. The burden of H. pylori antibiotic resistance in Africa is high with unclear information regarding the real magnitude. This systematic review and meta-analysis was conducted to investigate the magnitude (...) of H.pylori antibiotic resistance in Africa to gain insight of the extent of the problem among H.pylori naïve treatment patients.The search was performed in the academic databases, Embase, PubMed, Web of Science and Africa Wide Information. ProQuest Dissertation and Theses, Scopus, Ethos, Africa Index Medicus (WHO), BioMed Central Proceedings, BASE, British Library, Open grey, Library of Congress and the New York Academy of Grey Literature Report were additionally searched for grey literature. Published

2018 BMC Infectious Diseases

23. Automated annotation of mobile antibiotic resistance in Gram-negative bacteria: the Multiple Antibiotic Resistance Annotator (MARA) and database. Full Text available with Trip Pro

Automated annotation of mobile antibiotic resistance in Gram-negative bacteria: the Multiple Antibiotic Resistance Annotator (MARA) and database. Multiresistance in Gram-negative bacteria is often due to acquisition of several different antibiotic resistance genes, each associated with a different mobile genetic element, that tend to cluster together in complex conglomerations. Accurate, consistent annotation of resistance genes, the boundaries and fragments of mobile elements, and signatures (...) of insertion, such as DR, facilitates comparative analysis of complex multiresistance regions and plasmids to better understand their evolution and how resistance genes spread.To extend the Repository of Antibiotic resistance Cassettes (RAC) web site, which includes a database of 'features', and the Attacca automatic DNA annotation system, to encompass additional resistance genes and all types of associated mobile elements.Antibiotic resistance genes and mobile elements were added to RAC, from existing

2018 Journal of Antimicrobial Chemotherapy

24. Antimicrobial resistance: summary report on progress made in implementing resolution WHA67.25 on antimicrobial resistance: report by the Secretariat

Antimicrobial resistance: summary report on progress made in implementing resolution WHA67.25 on antimicrobial resistance: report by the Secretariat Antimicrobial resistance: summary report on progress made in implementing resolution WHA67.25 on antimicrobial resistance: report by the Secretariat JavaScript is disabled for your browser. Some features of this site may not work without it. Toggle navigation Toggle navigation Search Browse Statistics Related Links Antimicrobial resistance: summary (...) report on progress made in implementing resolution WHA67.25 on antimicrobial resistance: report by the Secretariat View/ Open View Statistics Altmetrics Share Citation World Health Assembly, 68 . (‎2015)‎. Antimicrobial resistance: summary report on progress made in implementing resolution WHA67.25 on antimicrobial resistance: report by the Secretariat. World Health Organization. Gov't Doc # A68/19 Collections Language English Metadata Related items Showing items related by title and MeSH subject

2015 WHO

25. Antimicrobial resistance: Draft global action plan on antimicrobial resistance: report by the Secretariat

Antimicrobial resistance: Draft global action plan on antimicrobial resistance: report by the Secretariat Antimicrobial resistance: draft global action plan on antimicrobial resistance: report by the Secretariat JavaScript is disabled for your browser. Some features of this site may not work without it. Toggle navigation Toggle navigation Search Browse Statistics Related Links Antimicrobial resistance: draft global action plan on antimicrobial resistance: report by the Secretariat View/ Open (...) View Statistics Altmetrics Share Citation World Health Assembly, 68 . (‎2015)‎. Antimicrobial resistance: draft global action plan on antimicrobial resistance: report by the Secretariat. World Health Organization. Gov't Doc # A68/20 Collections Language English Metadata Related items Showing items related by title and MeSH subject.  Executive Board, 136 (‎ EB136/20 , 2015 )‎  World Health Assembly, 68 (‎ A68/19 , 2015 )‎  Executive Board, 136 (‎ EB136/19 , 2015 )‎ View Item

2015 WHO

26. Universal Glove and Gown Use and Acquisition of Antibiotic-Resistant Bacteria in the ICU: A Randomized Trial

Universal Glove and Gown Use and Acquisition of Antibiotic-Resistant Bacteria in the ICU: A Randomized Trial PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2016 PedsCCM Evidence-Based Journal Club

27. Resolution of fluoroquinolone-resistant Escherichia coli keratitis with a PROSE device for enhanced targeted antibiotic delivery Full Text available with Trip Pro

Resolution of fluoroquinolone-resistant Escherichia coli keratitis with a PROSE device for enhanced targeted antibiotic delivery To report the resolution of a fluoroquinolone-resistant Escherichia coli keratitis with use of a prosthetic replacement of the ocular surface ecosystem (PROSE) device for enhanced targeted delivery of moxifloxiacin.A 62-year-old female presented with a 3-day history of pain, photophobia, and declining vision in left eye. The patient had a 2-year history of binocular (...) therapy. Frequent dosing to the PROSE reservoir is likely to increase fluoroquinolone bioavailability and may represent a valuable approach to overcome antibiotic resistance.

2018 American journal of ophthalmology case reports

28. Epidemiology of antibiotic-resistant wound infections from six countries in Africa Full Text available with Trip Pro

Epidemiology of antibiotic-resistant wound infections from six countries in Africa Little is known about the antimicrobial susceptibility of common bacteria responsible for wound infections from many countries in sub-Saharan Africa.We performed a retrospective review of microbial isolates collected based on clinical suspicion of wound infection between 2004 and 2016 from Mercy Ships, a non-governmental organisation operating a single mobile surgical unit in Benin, Congo, Liberia, Madagascar (...) surveillance should be a priority and local antimicrobial resistance profiles should be used to guide empiric antibiotic selection.

2018 BMJ global health

29. Machine Learning Leveraging Genomes from Metagenomes Identifies Influential Antibiotic Resistance Genes in the Infant Gut Microbiome Full Text available with Trip Pro

Machine Learning Leveraging Genomes from Metagenomes Identifies Influential Antibiotic Resistance Genes in the Infant Gut Microbiome Antibiotic resistance in pathogens is extensively studied, and yet little is known about how antibiotic resistance genes of typical gut bacteria influence microbiome dynamics. Here, we leveraged genomes from metagenomes to investigate how genes of the premature infant gut resistome correspond to the ability of bacteria to survive under certain environmental (...) are those that encode subclass B2 beta-lactamases and transcriptional regulators of vancomycin resistance. This demonstrates that machine learning applied to genome-resolved metagenomics data can identify key genes for survival after antibiotics treatment and predict how organisms in the gut microbiome will respond to antibiotic administration. IMPORTANCE The process of reconstructing genomes from environmental sequence data (genome-resolved metagenomics) allows unique insight into microbial systems. We

2018 mSystems

30. Antibiotic resistance patterns of urinary tract pathogens in Turkish children Full Text available with Trip Pro

Antibiotic resistance patterns of urinary tract pathogens in Turkish children Knowledge of local antimicrobial resistance patterns is essential for evidence- based empirical antibiotic prescribing. We aimed to investigate the distribution and changes in causative agents of urinary tract infections in children and the resistance rates, and to recommend the most appropriate antibiotics.In this retrospective study, we evaluated causative agents and antimicrobial resistance in urine isolates from (...) the positive community from September 2014 to April 2016 in a single hospital in Ankara, Turkey.A total of 850 positive urine cultures were identified, of which 588 (69.2%) were from girls and 262 (30.8%) were from boys. Their mean age was 36.5 ± 45.0 months. The most common causative agent was Escherichia coli (64.2% of cases) followed by Klebsiella pneumoniae (14.9%). The overall resistance to ampicillin (62.6%), cephalothin (44.2%), co-trimoxazole (29.8%) and cefuroxime (28.7%) was significant

2018 Global health research and policy

31. Regulation of virulence and antibiotic resistance in Gram-positive microbes in response to cell wall-active antibiotics. (Abstract)

Regulation of virulence and antibiotic resistance in Gram-positive microbes in response to cell wall-active antibiotics. Antibiotic stress can evoke considerable genotypic and phenotypic changes in Gram-positive bacteria. Here, we review recent studies describing altered virulence expression in response to cell wall-acting antibiotics and discuss mechanisms that coordinate regulation of the antibiotic response.Pleiotropic effects induced by antibiotic exposure include alterations to bacterial (...) metabolism, cell wall structure and antibiotic resistance. In addition, subinhibitory concentrations of cell wall-active (CWA) antibiotics have increasingly been shown to induce the production of exotoxins and biofilm formation that may influence virulence. Remarkably, phenotypes associated with comparable antibiotic stresses can vary considerably, emphasizing the need to better understand the response to CWA antibiotics. Recent studies support both direct antibiotic recognition and recognition

2019 Current Opinion in Infectious Diseases

32. Exploring patients' understanding of antibiotic resistance and how this may influence attitudes towards antibiotic use for acute respiratory infections: a qualitative study in Australian general practice. Full Text available with Trip Pro

Exploring patients' understanding of antibiotic resistance and how this may influence attitudes towards antibiotic use for acute respiratory infections: a qualitative study in Australian general practice. To explore patients' or parents of child patients' understanding of antibiotic resistance and aspects of resistance such as resistance reversibility and its spread among those in close proximity, along with how this may influence attitudes towards antibiotic use for acute respiratory (...) infections (ARIs).Qualitative semistructured interview study using convenience sampling and thematic analysis by two researchers independently.General practices in Gold Coast, Australia.32 patients or parents of child patients presenting to general practice with an ARI.Five themes emerged: (1) antibiotic use is seen as the main cause of antibiotic resistance, but what it is that becomes resistant is poorly understood; (2) resistance is perceived as a future 'big problem' for the community, with little

2019 BMJ open

33. Parents' perceptions of antibiotic use and antibiotic resistance (PAUSE): a qualitative interview study. Full Text available with Trip Pro

of unnecessary antibiotic use and antibiotic resistance needs to focus on outcomes that parents of young children can relate to (e.g. infection recurrence) and in a format that parents will engage with (e.g. face-to-face dissemination at playgroups and parent/child community events) to make a more informed decision about the risks and benefits of antibiotics for their child.© The Author(s) 2019. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. (...) Parents' perceptions of antibiotic use and antibiotic resistance (PAUSE): a qualitative interview study. There remains public misconception about antibiotic use and resistance. Preschool children are at particular risk of receiving unnecessary antibiotics because they commonly present in primary care and many childhood infections are self-limiting.The aim of our study was to explore parents' perceptions and understanding of antibiotic use and resistance in the context of their young child

2019 Journal of Antimicrobial Chemotherapy

34. Successful treatment of antibiotic resistant poly-microbial bone infection with bacteriophages and antibiotics combination. Full Text available with Trip Pro

Successful treatment of antibiotic resistant poly-microbial bone infection with bacteriophages and antibiotics combination. A patient with a trauma-related left tibial infection associated with extensively drug-resistant Acinetobacter baumannii and multidrug-resistant Klebsiella pneumoniae was treated with bacteriophages and antibiotics. There was rapid tissue healing and positive culture eradication. As a result, the patient's leg did not have to be amputated and he is undergoing

2019 Clinical Infectious Diseases

35. Prevalence of antibiotic resistance in fecal flora before transrectal ultrasound-guided prostate biopsy and the clinical impact of targeted antibiotic prophylaxis. (Abstract)

Prevalence of antibiotic resistance in fecal flora before transrectal ultrasound-guided prostate biopsy and the clinical impact of targeted antibiotic prophylaxis. In this study, we aimed to evaluate ciprofloxacin resistance and the presence of extended-spectrum beta-lactamase producing organisms (ESBLs) in the population of patients with indication to undergo prostate biopsy. Our additional aim was to compare the targeted antibiotic prophylaxis and sepsis rates after transrectal ultrasound (...) (10.4%). There were no statistically significant differences between antibiotic resistance and urologic operations, urinary tract infections, prior catheterization history, the presence of a catheter during prostate biopsy and antibiotic usage history due to a high PSA level.In our study, the rates of ESBL presence and ciprofloxacin resistance in rectal flora were not negligible. However, by obtaining rectal swab cultures prior to performing transrectal prostate biopsies and using targeted

2019 Archivos Espanoles de Urologia Controlled trial quality: uncertain

36. Knowledge of antibiotics and antibiotic resistance among Norwegian pharmacy customers - a cross-sectional study. Full Text available with Trip Pro

Knowledge of antibiotics and antibiotic resistance among Norwegian pharmacy customers - a cross-sectional study. Antibiotic resistance is a global health threat. Public knowledge is considered a prerequisite for appropriate use of antibiotics and limited spread of antibiotic resistance. Our aim was to examine the level of knowledge of antibiotics and antibiotic resistance among Norwegian pharmacy customers, and to assess to which degree beliefs, attitudes and sociodemographic factors (...) are associated with this knowledge.A questionnaire based, cross-sectional study was conducted among pharmacy customers in three Norwegian cities. The questionnaire covered 1) knowledge of antibiotics (13 statements) and antibiotic resistance (10 statements), 2) the general beliefs about medicines questionnaire (BMQ general) (three subdomains, four statements each), 3) attitudes toward antibiotic use (four statements), and 4) sociodemographic factors, life style and health. High knowledge level was defined

2019 BMC Public Health

37. Detection of antibiotic resistance genes from blood cultures: performance assessment and potential impact on antibiotic therapy management. (Abstract)

Detection of antibiotic resistance genes from blood cultures: performance assessment and potential impact on antibiotic therapy management. Molecular assays may constitute a valid method for timely prediction of antimicrobial resistance and optimization of empirical antibiotic therapies. This study assessed ELITe MGB assays of blood cultures to detect the main carbapenemase and extended-spectrum beta-lactamase (ESBL) genes, Staphylococcus aureus and mec genes in less than 3 h. Excellent (...) agreement was found between the results of genotypic and conventional phenotypic approaches. Retrospective analysis of medical records revealed that approximately 50% of bloodstream infections caused by ESBL-producing Enterobacteriaceae, carbapenemase-producing Enterobacteriaceae or meticillin-resistant S. aureus were initially treated with inactive drugs. Overall, 36.3% of patients could have been treated with appropriate therapy at least 24 h earlier if molecular data had been used.Copyright © 2019

2019 Journal of Hospital Infection

38. Retraction of: Antibiotic Resistance in Salmonella Enteritidis Isolates Recovered from Chicken, Chicken Breast, and Humans Through National Antimicrobial Resistance Monitoring System Between 1996 and 2014, by Paudyal N, Pan H, Li X, Fang W, Yue M.Foodborn Full Text available with Trip Pro

Retraction of: Antibiotic Resistance in Salmonella Enteritidis Isolates Recovered from Chicken, Chicken Breast, and Humans Through National Antimicrobial Resistance Monitoring System Between 1996 and 2014, by Paudyal N, Pan H, Li X, Fang W, Yue M.Foodborn 30334658 2019 03 13 1556-7125 15 10 2018 10 Foodborne pathogens and disease Foodborne Pathog. Dis. Retraction of: Antibiotic Resistance in Salmonella Enteritidis Isolates Recovered from Chicken, Chicken Breast, and Humans Through National (...) Antimicrobial Resistance Monitoring System Between 1996 and 2014, by Paudyal N, Pan H, Li X, Fang W, Yue M. Foodborne Pathog Dis [Epub ahead of print]; DOI: 10.1089/fpd.2017.2402. 669 10.1089/fpd.2017.2402.retract eng Journal Article Retraction of Publication United States Foodborne Pathog Dis 101120121 1535-3141 Foodborne Pathog Dis. 2018 Oct 3;: 29927626 2018 10 19 6 0 2018 10 20 6 0 2018 10 20 6 1 ppublish 30334658 10.1089/fpd.2017.2402.retract PMC6205040 Clin Infect Dis. 2014 Nov 1;59(9):e139-41

2018 Foodborne pathogens and disease

39. Antibiotic Resistance and Azithromycin Resistance Mechanism of Legionella pneumophila Serogroup 1 in China. (Abstract)

Antibiotic Resistance and Azithromycin Resistance Mechanism of Legionella pneumophila Serogroup 1 in China. Legionnaires' disease, caused by Legionella pneumophila, has been treated primarily with antibiotics. However, few reports have been published on antibiotic-resistant Legionella in China. Our aim was to determine the azithromycin resistance mechanism of L. pneumophila serogroup 1 in China. The sensitivities of 149 L. pneumophila serogroup 1 strains, isolated from clinical cases (...) or environmental water in China from 2002 to 2016, to five antibiotics, including erythromycin, azithromycin, levofloxacin, moxifloxacin, and rifampin, were evaluated. The mechanisms of the resistance of L. pneumophila serogroup 1 to azithromycin were studied. The expression levels of efflux pump gene lpeAB and the MIC of azithromycin-resistant strains in the presence and absence of the efflux pump inhibitor carbonyl cyanide-chlorophenylhydrazone (CCCP) were determined. All 149 strains were sensitive

2019 Antimicrobial Agents and Chemotherapy

40. Antibiotic resistance profiles and multidrug resistance patterns of Streptococcus pneumoniae in pediatrics: A multicenter retrospective study in mainland China. Full Text available with Trip Pro

Antibiotic resistance profiles and multidrug resistance patterns of Streptococcus pneumoniae in pediatrics: A multicenter retrospective study in mainland China. Emergent resistance to antibiotics among Streptococcus pneumoniae isolates is a severe problem worldwide. Antibiotic resistance profiles for S pneumoniae isolates identified from pediatric patients in mainland China remains to be established.The clinical features, antimicrobial resistance, and multidrug resistance patterns of S (...) the proportions of ceftriaxone resistance were 8.2% and 18.1%, respectively. Pneumococcal conjugate vaccine was administered to only 4.1% of patients. Penicillin and ceftriaxone resistance, underling diseases, antibiotic resistant risk factors, and poor prognosis appeared more frequently in invasive pneumococcal diseases. The incidence of multidrug resistance (MDR) was 46.1% in patients with invasive pneumococcal disease which was more than in patients with non-invasive pneumococcal disease (18.3%). Patients

2019 Medicine

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>