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antibiotic resistance

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1. Topical Antibiotics for the Treatment of Treatment-Resistant Impetigo: Clinical Effectiveness and Guidelines

Topical Antibiotics for the Treatment of Treatment-Resistant Impetigo: Clinical Effectiveness and Guidelines Topical Antibiotics for the Treatment of Treatment-Resistant Impetigo: Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Topical Antibiotics for the Treatment of Treatment-Resistant Impetigo: Clinical Effectiveness and Guidelines Topical Antibiotics for the Treatment of Treatment-Resistant Impetigo: Clinical Effectiveness and Guidelines Last updated: October (...) 4, 2018 Project Number: RA0968-000 Product Line: Research Type: Drug Report Type: Reference List Result type: Report Question What is the clinical evidence regarding the use of topical antibiotics for the treatment of treatment-resistant impetigo? What are the evidence-based guidelines regarding the treatment of treatment resistant impetigo? Key Message One systematic review with meta-analyses, one non-randomized study, and one evidence-based guideline were identified regarding the clinical

2018 Canadian Agency for Drugs and Technologies in Health - Rapid Review

2. Is the use of chlorhexidine contributing to increased resistance to chlorhexidine and/or antibiotics?

’ defined by using the clinical breakpoints for resistance as specified by the European Committee on Antimicrobial Susceptibility testing (EUCAST) or the Clinical and Laboratory Standards Institute (CSLI). 2. Increase in the incidence (rate) of antibiotic-resistant strains of bacteria established through the use of chlorhexidine identifying dosage form, exposure and specific population and / or setting. Antibiotic-resistant strain of bacteria through the use of chlorhexidine to be recorded. 3. Increases (...) to chlorhexidine in a specific population and / or setting. To address the question ‘Does exposure (different dosages, duration of use, and stratification of exposure) to any form of chlorhexidine increases the incidence and/or prevalence of antibiotic- resistant strains of bacteria in any person within different healthcare settings? ’ the outcomes included: ? ‘Resistance against antibiotics’ defined by using the clinical breakpoints for resistance as specified by the European Committee on Antimicrobial

2018 National Health and Medical Research Council

3. Emergence of antibiotic resistance in immunocompromised host populations: A case study of emerging antibiotic resistant tuberculosis in AIDS patients. Full Text available with Trip Pro

Emergence of antibiotic resistance in immunocompromised host populations: A case study of emerging antibiotic resistant tuberculosis in AIDS patients. The evolution of antibiotic resistance is far outpacing the development of new antibiotics, causing global public health concern about infections that will increasingly be unresponsive to antimicrobials. This risk of emerging antibiotic resistance may be meaningfully altered in highly AIDS-immunocompromised populations. Such populations (...) fundamentally alter the bacterial evolutionary landscape in two ways, which we seek to model and analyze. First, widespread, population-level immunoincompetence creates a novel host environment with disrupted selective pressures. Second, within AIDS-prevalent populations, the recommendation that antibiotics be taken to treat and prevent opportunistic infection raises the risk of selection for drug-resistant pathogens.To determine the impact of HIV/AIDS on the emergence of antibiotic resistance-specifically

2019 PLoS ONE

4. AbGRI4, a novel antibiotic resistance island in multiply antibiotic-resistant Acinetobacter baumannii clinical isolates. Full Text available with Trip Pro

AbGRI4, a novel antibiotic resistance island in multiply antibiotic-resistant Acinetobacter baumannii clinical isolates. To investigate the genomic context of a novel resistance island (RI) in multiply antibiotic-resistant Acinetobacter baumannii clinical isolates and global isolates.Using a combination of long and short reads generated from the Oxford Nanopore and Illumina platforms, contiguous chromosomes and plasmid sequences were determined. BLAST-based analysis was used to identify the RI (...) insertion target.Genomes of four multiply antibiotic-resistant A. baumannii clinical strains, from a US hospital system, belonging to prevalent MLST ST2 (Pasteur scheme) and ST281 (Oxford scheme) clade F isolates were sequenced to completion. A class 1 integron carrying aadB (tobramycin resistance) and aadA2 (streptomycin/spectinomycin resistance) was identified. The class 1 integron was 6.8 kb, bounded by IS26 at both ends, and embedded in a new target location between an α/β-hydrolase and a reductase

2020 Journal of Antimicrobial Chemotherapy

5. Integrated one-day surveillance of antimicrobial use, antimicrobial consumption, antimicrobial resistance, healthcare-associated infection, and antimicrobial resistance burden among hospitalized patients in Thailand. (Abstract)

Integrated one-day surveillance of antimicrobial use, antimicrobial consumption, antimicrobial resistance, healthcare-associated infection, and antimicrobial resistance burden among hospitalized patients in Thailand. Surveillance of antimicrobial use (AMU), antimicrobial consumption (AMC), antimicrobial resistance (AMR), healthcare-associated infection (HAI), and AMR burden are usually measured by time-consuming and expensive multiple separate longitudinal surveys. This study aimed (...) , respectively. The most common infection was pneumonia. Community-associated infection (CAI) was observed in 64.9%, and 34.1% had HAI. Prevalence of AMR was highest in A. baumannii infection. AMR in bacteria was more prevalent among HAI than among CAI. Consumption of all antibiotics was 18,103 defined daily doses. HAI prevalence was 14.0%. Health and economic burden were much higher in patients with antibiotic-resistant infection.Integrated one-day surveillance of these important parameters among

2020 Journal of Infection

6. Are Latino Cultural Beliefs Increasing Antibiotic Resistance in the US?

better strategies to control the rise of antimicrobial resistant pathogens—a major global public health problem. Latin American countries have fewer restrictions on the sale of antimicrobial agents, and the existing . 3 This enables the self-diagnosing and self-medicating practices that many members of the Latino community are accustomed to. Furthermore, cultural beliefs and misconceptions regarding the purpose and function of antibiotics play a major role in their misuse among the Latino population (...) Are Latino Cultural Beliefs Increasing Antibiotic Resistance in the US? Are Latino Cultural Beliefs Increasing Antibiotic Resistance in the US? – Clinical Correlations Search Are Latino Cultural Beliefs Increasing Antibiotic Resistance in the US? June 8, 2018 3 min read By Daniela Rebollo Salazar Peer Reviewed In the past ten years, the number of bacterial pathogens resistant to multiple antibiotics has dramatically increased. The emergence of resistant microorganisms is a direct product

2018 Clinical Correlations

7. Antimicrobial resistance (AMR): applying All Our Health

prevent ill health and promote wellbeing as part of their everyday practice. The information below will help front-line health and care staff use their trusted relationships with patients, families and communities to promote the benefits of preventing antimicrobial resistance ( of ‘All Our Health’ topics. Infections that cannot be treated continue to develop. The rapid spread of multidrug resistant organisms means that we may not be able to treat everyday infections or diseases with antibiotics (...) in the near future. Many existing antimicrobials are becoming less effective as bacteria, viruses, protozoa and fungi are adapting and becoming resistant to medicines. Inappropriate use of these valuable medicines has also added to the problem. Without effective antibiotics, even minor surgery and routine operations could become high risk procedures if serious infections can’t be treated. Access the antimicrobial resistance e-learning session An is now available to use. and 5 Year Action Plan set out

2019 Public Health England

8. Gastric juice-based genotypic methods for diagnoses of Helicobacter pylori infection and antibiotic resistance testing: a systematic review and meta-analysis Full Text available with Trip Pro

Gastric juice-based genotypic methods for diagnoses of Helicobacter pylori infection and antibiotic resistance testing: a systematic review and meta-analysis Gastric juice-based genotypic methods for diagnoses of Helicobacter pylori infection and antibiotic resistance testing: a systematic review and meta-analysis EISSN 2148-5607 Turkish Journal of Gastroenterology Toggle navigation Turkish Journal of Gastroenterology HIGHLY CITED ARTICLES By: Aydin, M. Merve; Akcali, Kamil Can By: Besheer (...) , Tarek; Arafa, Mona M.; Abd El-Maksoud, Mohamed; et al. By: Yilmaz, Ilkay; Dolar, M. Enver; Ozpinar, Haydar By: Demir, Meryem; Deyneli, Oguzhan; Yilmaz, Yusuf By: Tozlu, Mukaddes; Kayar, Yusuf; Ince, Ali Tuzun; et al. By: Bashiri, Mehrnoosh; Akcali, Didem; Coskun, Demet; et al. Gastric juice-based genotypic ... Original Article Gastric juice-based genotypic methods for diagnoses of Helicobacter pylori infection and antibiotic resistance testing: a systematic review and meta-analysis , , , , 1

2020 The Turkish Journal of Gastroenterology

9. F1000Prime recommendation of Prevalence of antibiotic resistance in helicobacter pylori: a systematic review and meta-analysis in world health organization regions. Full Text available with Trip Pro

F1000Prime recommendation of Prevalence of antibiotic resistance in helicobacter pylori: a systematic review and meta-analysis in world health organization regions. Prevalence of antibiotic resistance in helicobacter... | Faculty Opinions On April 12th, 2020, F1000Prime became Faculty Opinions. See our to learn more. Welcome Guest 1 Recommendations info_outline Systematic Review / Meta-analysis New Finding close Classified As New Finding 1 Article Type Systematic Review / Meta-analysis More (...) more_vert close Download article Export article Sciwheel Download citation BibTeX RIS Share Email Prevalence of antibiotic resistance in helicobacter pylori: a systematic review and meta-analysis in world health organization regions. ARTICLE PUBLISHED: 2018 11 CITE AS: Gastroenterology. 2018 11 ; 155 ( 5 ): 1372-1382.e17 Recommendations Abstract Comments You have reached your article limit. Register for 30-day free trial Registration is free and only takes a moment, or subscribe for unlimited access

2020 Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature

10. Bacterial antibiotic resistance development and mutagenesis following exposure to subinhibitory concentrations of fluoroquinolones in vitro: a systematic review of the literature Full Text available with Trip Pro

Bacterial antibiotic resistance development and mutagenesis following exposure to subinhibitory concentrations of fluoroquinolones in vitro: a systematic review of the literature Bacterial antibiotic resistance development and mutagenesis following exposure to subinhibitory concentrations of fluoroquinolones in vitro: a systematic review of the literature | JAC-Antimicrobial Resistance | Oxford Academic ') We use cookies to enhance your experience on our website.By continuing to use our website (...) on: JAC-Antimicrobial Resistance , Volume 2, Issue 3, September 2020, dlaa068, Published: 30 September 2020 Received: 14 April 2020 Accepted: 15 July 2020 Published: 30 September 2020 Cite Carly Ching, Ebiowei S F Orubu, Indorica Sutradhar, Veronika J Wirtz, Helen W Boucher, Muhammad H Zaman, Bacterial antibiotic resistance development and mutagenesis following exposure to subinhibitory concentrations of fluoroquinolones in vitro : a systematic review of the literature, JAC-Antimicrobial Resistance

2020 JAC-Antimicrobial Resistance

11. How effective are strategies to control the dissemination of antibiotic resistance in the environment? A systematic review Full Text available with Trip Pro

How effective are strategies to control the dissemination of antibiotic resistance in the environment? A systematic review How effective are strategies to control the dissemination of antibiotic resistance in the environment? A systematic review | Environmental Evidence | Full Text Search Search all BMC articles Search How effective are strategies to control the dissemination of antibiotic resistance in the environment? A systematic review , , , , , , , , , , , , , , , , , , , , , & , volume 9 (...) , Article number: 4 ( 2020 ) 3492 Accesses 3 Citations 33 Altmetric The to this article has been published in Environmental Evidence 2018 7 :3 Abstract Background Antibiotic resistance is a major concern for public and environmental health. The role played by the environment in disseminating resistance is increasingly considered, as well as its capacity for mitigation. We reviewed the literature on strategies to control dissemination of antibiotic-resistant bacteria (ARB), antibiotic resistance genes

2020 Environmental evidence

12. Neonatal infection: antibiotics for prevention and treatment

-choice antibiotic regimen for empirical treatment of suspected early-onset infection, unless microbiological surveillance data show local bacterial resistance patterns that indicate the need for a different antibiotic. [2012] [2012] 1.5.2 Give benzylpenicillin in a dosage of 25 mg/kg every 12 hours. Consider shortening the dose interval to every 8 hours, based on clinical judgement (for example, if the baby appears very ill). [2012] [2012] 1.5.3 Give gentamicin in a starting dose of 5 mg/kg (see (...) review G: investigations before starting treatment. 1.10 1.10 Antibiotics for late-onset neonatal infection Antibiotics for late-onset neonatal infection Choice of antibiotics Choice of antibiotics 1.10.1 For babies with suspected late-onset neonatal infection who are already in a neonatal unit: • give a combination of narrow-spectrum antibiotics (such as intravenous flucloxacillin plus gentamicin) as first-line treatment • use local antibiotic susceptibility and resistance data (or national data

2021 National Institute for Health and Clinical Excellence - Clinical Guidelines

13. Infectious Diseases Society of America Guidance on the Treatment of Antimicrobial Resistant Gram-Negative Infections

, antimicrobial resistant pathogens caused more than 2.8 million infections and over 35,000 deaths annually in the United States from 2012 through 2017, according to the 2019 Centers for Disease Control and Prevention (CDC) Antibiotic Resistant Threats Report [2]. The selection of effective antibiotics for the treatment of infections by resistant pathogens is challenging [3]. Although there has been an increase in the availability of novel antibiotics to combat resistant infections in recent years [3 (...) will be disseminated on multiple platforms and updated as new data emerge. Treatment of antimicrobial resistant Gram-negative bacterial infections was chosen as the initial topic for a guidance document. The overarching goal of this guidance document is to assist clinicians – including those with and without infectious diseases expertise – in selecting antibiotic therapy for infections caused by ESBL-E, CRE, and DTR- P. aeruginosa . Future iterations of this document will address other resistant pathogens

2020 Infectious Diseases Society of America

14. Selection and co-selection of antibiotic resistances among Escherichia coli by antibiotic use in primary care: An ecological analysis. Full Text available with Trip Pro

Selection and co-selection of antibiotic resistances among Escherichia coli by antibiotic use in primary care: An ecological analysis. The majority of studies that link antibiotic usage and resistance focus on simple associations between the resistance against a specific antibiotic and the use of that specific antibiotic. However, the relationship between antibiotic use and resistance is more complex. Here we evaluate selection and co-selection by assessing which antibiotics, including those (...) mainly prescribed for respiratory tract infections, are associated with increased resistance to various antibiotics among Escherichia coli isolated from urinary samples.Monthly primary care prescribing data were obtained from National Health Service (NHS) Digital. Positive E. coli records from urine samples in English primary care (n = 888,207) between April 2014 and January 2016 were obtained from the Second Generation Surveillance System. Elastic net regularization was used to evaluate associations

2019 PLoS ONE

15. Gross national income and antibiotic resistance in invasive isolates: analysis of the top-ranked antibiotic-resistant bacteria on the 2017 WHO priority list. (Abstract)

(15.3%, 95% CI 11.6%-19.1%). The rate of increase per unit decrease in log GNI per capita was lower in MRSA (9.5%, 95% CI 5.2%-13.7%).The prevalence of invasive infections caused by the WHO top-ranked antibiotic-resistant bacteria is inversely associated with GNI per capita at the global level. Public health interventions designed to limit the burden of antimicrobial resistance should also consider determinants of poverty and inequality, especially in lower-middle income and low income countries.© (...) Gross national income and antibiotic resistance in invasive isolates: analysis of the top-ranked antibiotic-resistant bacteria on the 2017 WHO priority list. To assess the association between country income status and national prevalence of invasive infections caused by the top-ranked bacteria on the WHO priority list: carbapenem-resistant (CR) Acinetobacter spp., Klebsiella spp. and Pseudomonas aeruginosa; third-generation cephalosporin-resistant (3GCR) Escherichia coli and Klebsiella spp

2019 Journal of Antimicrobial Chemotherapy

16. Factors affecting the geographic variability of antibiotic-resistant healthcare-associated infections in the United States using the CDC Antibiotic Resistance Patient Safety Atlas. (Abstract)

Factors affecting the geographic variability of antibiotic-resistant healthcare-associated infections in the United States using the CDC Antibiotic Resistance Patient Safety Atlas. We utilized publicly available data from the Centers for Disease Control to explore possible causes of state-to-state variability in antibiotic-resistant healthcare-associated infections. Outpatient antibiotic prescribing rates of fluoroquinolones and cephalosporins explained some variability in extended-spectrum (...) cephalosporin-resistant Escherichia coli after adjusting for differences in age and healthcare facility composition.

2019 Infection control and hospital epidemiology

17. Antibiotic resistance among bacterial conjunctival pathogens collected in the Antibiotic Resistance Monitoring in Ocular Microorganisms (ARMOR) surveillance study. Full Text available with Trip Pro

Antibiotic resistance among bacterial conjunctival pathogens collected in the Antibiotic Resistance Monitoring in Ocular Microorganisms (ARMOR) surveillance study. The Antibiotic Resistance Monitoring in Ocular Microorganisms (ARMOR) surveillance study evaluates in vitro antibiotic resistance among Staphylococcus aureus, coagulase-negative staphylococci (CoNS), Streptococcus pneumoniae, Pseudomonas aeruginosa, and Haemophilus influenzae isolates from ocular infections. Here we report resistance (...) rates and trends among conjunctival-sourced ocular isolates collected across the US from 2009 through 2016. A total of 1198 conjunctival isolates (483 S. aureus, 305 CoNS, 208 H. influenzae, 118 S. pneumoniae, and 84 P. aeruginosa) were collected from patients with presumed bacterial conjunctivitis from 57 sites across 40 states. A large proportion of staphylococci demonstrated resistance to oxacillin and azithromycin, while resistance was low against the majority of antibiotics tested for S

2018 PLoS ONE

18. Correction: Impact of extensive antibiotic treatment on faecal carriage of antibiotic-resistant enterobacteria in children in a low resistance prevalence setting. Full Text available with Trip Pro

Correction: Impact of extensive antibiotic treatment on faecal carriage of antibiotic-resistant enterobacteria in children in a low resistance prevalence setting. [This corrects the article DOI: 10.1371/journal.pone.0187618.].

2018 PLoS ONE

19. Antibiotic awareness: important messages on antibiotic use

produced a short video to help explain the issue of antibiotic resistance: : If you are planning to use social media to promote the campaign don’t forget to use the #AntibioticGuardian hashtag. For copies of Tweetable graphics or messages, please email . Further resources Published 23 September 2014 Last updated 7 October 2019 7 October 2019 Added 'Antibiotic Awareness: key messages 2019'. 20 October 2017 Updated with 2017 document. 3 November 2016 Uploaded 2016 version of PDF. 6 October 2015 Updated (...) Antibiotic awareness: important messages on antibiotic use Antibiotic awareness: important messages on antibiotic use - GOV.UK GOV.UK uses cookies which are essential for the site to work. We also use non-essential cookies to help us improve government digital services. Any data collected is anonymised. By continuing to use this site, you agree to our use of cookies. Accept cookies You’ve accepted all cookies. You can at any time. Hide Search Guidance Antibiotic awareness: important messages

2019 Public Health England

20. Tailored Helicobacter pylori eradication based on prior intake of macrolide antibiotics allows the use of triple therapy with optimal results in an area with high clarithromycin resistance. Full Text available with Trip Pro

Tailored Helicobacter pylori eradication based on prior intake of macrolide antibiotics allows the use of triple therapy with optimal results in an area with high clarithromycin resistance. the previous intake of macrolide antibiotics is associated with a failure to eradicate Helicobacter pylori (H. pylori) with clarithromycin-containing regimens. However, the standard triple therapy achieves eradication rates of over 90% in patients without a previous use of macrolides in our health area (...) in more than half of the patients from a health area with a high level of clarithromycin resistance.

2019 Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva Controlled trial quality: uncertain

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