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5201. Pilot Study Examining Effect for Dextroamphetamine to Treat Cocaine Dependence Plus Attention-deficit Hyperactivity Disorder (ADHD)

Posted: February 22, 2012 Last Verified: February 2012 Keywords provided by The University of Texas Health Science Center, Houston: cocaine ADHD attention hyperactivity drug dependence Additional relevant MeSH terms: Layout table for MeSH terms Disease Attention Deficit Disorder with Hyperactivity Hyperkinesis Cocaine-Related Disorders Substance-Related Disorders Pathologic Processes Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders Dyskinesias (...) . Thus, the present pilot study will determine the ability of dextroamphetamine to treat individuals with both cocaine dependence and ADHD. Condition or disease Intervention/treatment Phase Attention Deficit Disorder With Hyperactivity Cocaine-Related Disorders Substance-Related Disorders Drug: Placebo Drug: Dextroamphetamine SR Phase 2 Detailed Description: This double-blind, placebo-controlled pilot study will determine the ability of dextroamphetamine to treat comorbid cocaine dependence and ADHD

2007 Clinical Trials

5202. Efficacy and Effectiveness of Methylphenidate in Swedish Male Prison Inmates With Attention-deficit Hyperactivity Disorder (ADHD)

Disorder ADHD Prison Treatment Randomized Double-Blind Placebo Control Parallel Assignment Efficacy Study Additional relevant MeSH terms: Layout table for MeSH terms Attention Deficit Disorder with Hyperactivity Hyperkinesis Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders Dyskinesias Neurologic Manifestations Nervous System Diseases Signs and Symptoms Methylphenidate Central Nervous System Stimulants Physiological Effects of Drugs Dopamine Uptake (...) Efficacy and Effectiveness of Methylphenidate in Swedish Male Prison Inmates With Attention-deficit Hyperactivity Disorder (ADHD) Efficacy and Effectiveness of Methylphenidate in Swedish Male Prison Inmates With Attention-deficit Hyperactivity Disorder (ADHD) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have

2007 Clinical Trials

5203. PET Scanning of Adults With Attention Deficit Hyperactivity Disorder (ADHD)

: November 27, 2012 Keywords provided by National Institutes of Health Clinical Center (CC): Phospholipase A2 D2 Receptors Apomorphine Trimethobenzamide Attention Deficit Hyperactivity Disorder ADHD Healthy Volunteer HV Additional relevant MeSH terms: Layout table for MeSH terms Disease Attention Deficit Disorder with Hyperactivity Hyperkinesis Pathologic Processes Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders Dyskinesias Neurologic Manifestations (...) of a saline solution and again after injection of apomorphine, a medication that turns on dopamine receptors in the brain. The injections are given under the skin of the abdomen, about one and a half hours apart. Condition or disease Volunteer Attention Deficit Hyperactivity Disorder Detailed Description: A. Objective Attention deficit hyperactivity disorder (ADHD) is a heritable neurodevelopmental disorder with a reported male predominance that persists into adulthood and leads to significant morbidity

2006 Clinical Trials

5204. Open Label, Multicentre Extension Study of Protocol 42603ATT3002 to Evaluate Safety of Prolonged Release OROS Methlyphenidate in Adults With Attention Deficit Hyperactivity Disorder (ADHD)

: CR011068 First Posted: March 28, 2006 Results First Posted: February 23, 2010 Last Update Posted: April 21, 2014 Last Verified: April 2014 Keywords provided by Janssen-Cilag International NV: Attention Deficit Hyperactivity Disorder Adult Long term safety Efficacy Quality of life Additional relevant MeSH terms: Layout table for MeSH terms Disease Attention Deficit Disorder with Hyperactivity Hyperkinesis Pathologic Processes Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental (...) Open Label, Multicentre Extension Study of Protocol 42603ATT3002 to Evaluate Safety of Prolonged Release OROS Methlyphenidate in Adults With Attention Deficit Hyperactivity Disorder (ADHD) Open Label, Multicentre Extension Study of Protocol 42603ATT3002 to Evaluate Safety of Prolonged Release OROS Methlyphenidate in Adults With Attention Deficit Hyperactivity Disorder (ADHD) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting

2006 Clinical Trials

5205. A Study of SPD465 in Young Adult Drivers With Attention-Deficit Hyperactivity Disorder (ADHD) Using Driving Simulators

provided by Shire: Attention-Deficit Hyperactivity Disorder (ADHD) Additional relevant MeSH terms: Layout table for MeSH terms Disease Attention Deficit Disorder with Hyperactivity Hyperkinesis Pathologic Processes Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders Dyskinesias Neurologic Manifestations Nervous System Diseases Signs and Symptoms (...) A Study of SPD465 in Young Adult Drivers With Attention-Deficit Hyperactivity Disorder (ADHD) Using Driving Simulators A Study of SPD465 in Young Adult Drivers With Attention-Deficit Hyperactivity Disorder (ADHD) Using Driving Simulators - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum

2007 Clinical Trials

5206. Atomoxetine for Treating Cocaine Abuse in Adults With Attention Deficit Hyperactivity Disorder (ADHD)

Levin, New York State Psychiatric Institute: ADHD Cocaine Abuse Additional relevant MeSH terms: Layout table for MeSH terms Disease Attention Deficit Disorder with Hyperactivity Hyperkinesis Cocaine-Related Disorders Pathologic Processes Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders Dyskinesias Neurologic Manifestations Nervous System Diseases Signs and Symptoms Substance-Related Disorders Chemically-Induced Disorders Cocaine Atomoxetine (...) of cocaine abuse in adults with ADHD are significantly higher than they are in adults who do not have ADHD. Some clinicians suggest that adults with ADHD may abuse cocaine in order to self-medicate their ADHD symptoms. Atomoxetine is a drug that has been effective in treating ADHD. This study will evaluate the effectiveness of atomoxetine in reducing cocaine use in people with ADHD who abuse cocaine. Condition or disease Intervention/treatment Phase Attention Deficit Disorder With Hyperactivity Cocaine

2005 Clinical Trials

5207. Study to Assess the Safety and Efficacy of NRP104 in Adults With Attention-Deficit Hyperactivity Disorder (ADHD)

Update Posted : July 2, 2009 Sponsor: New River Pharmaceuticals Information provided by: New River Pharmaceuticals Study Details Study Description Go to Brief Summary: The purpose of this study is to evaluate the safety and effectiveness of NRP104 administered as a daily morning dose (30, 50, and 70mg/day) compared to placebo in adults (18-55 years of age inclusive) diagnosed with moderate to severe Attention Deficit Hyperactivity Disorder (ADHD). Condition or disease Intervention/treatment Phase (...) Deficit Disorder with Hyperactivity Hyperkinesis Psychomotor Agitation Pathologic Processes Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders Dyskinesias Neurologic Manifestations Nervous System Diseases Signs and Symptoms Psychomotor Disorders Neurobehavioral Manifestations Lisdexamfetamine Dimesylate Central Nervous System Stimulants Physiological Effects of Drugs Dopamine Uptake Inhibitors Neurotransmitter Uptake Inhibitors Membrane Transport

2006 Clinical Trials

5208. Study to Evaluate the Efficacy of Modafinil Treatment in Patients With Attention Deficit Hyperactivity Disorder (ADHD) Who Are Responders to Modafinil Treatment

: Attention-Deficit/Hyper Activity Disorder ADHD Additional relevant MeSH terms: Layout table for MeSH terms Disease Attention Deficit Disorder with Hyperactivity Hyperkinesis Pathologic Processes Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders Dyskinesias Neurologic Manifestations Nervous System Diseases Signs and Symptoms Modafinil Central Nervous System Stimulants Physiological Effects of Drugs Wakefulness-Promoting Agents Cytochrome P-450 CYP3A (...) ) who are responders to modafinil treatment. Condition or disease Intervention/treatment Phase Attention Deficit Hyperactivity Disorder Drug: Modafinil Phase 3 Detailed Description: The primary objective of the study is to evaluate the continued efficacy of modafinil treatment, compared to placebo treatment, in children and adolescents with attention-deficit/hyperactivity disorder (ADHD) who are responders to modafinil treatment, as assessed by the change from baseline (in this current study

2006 Clinical Trials

5209. [The effectiveness of body-oriented methods of therapy in the treatment of attention-deficit hyperactivity disorder (ADHD): results of a controlled pilot study]. (Abstract)

[The effectiveness of body-oriented methods of therapy in the treatment of attention-deficit hyperactivity disorder (ADHD): results of a controlled pilot study]. Randomized controlled studies on the effectiveness of body-oriented methods of treatment for children with attention-deficit hyperactivity disorder (ADHD) are lacking. Our aim was to compare the effectiveness of two methods of treatment (yoga for children vs. conventional motor exercises) in a randomized controlled pilot study.Nineteen (...) showed sizable reductions in symptoms over time, and at the end of the study, the group means for the ADHD scales did not differ significantly from those for a representative control group. Furthermore, the training was particularly effective for children undergoing pharmacotherapy (MPH).The findings from this pilot study demonstrate that yoga can be an effective complementary or concomitant treatment for attention-deficit hyperactivity disorder. The study advocates further research into the impact

2006 Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie Controlled trial quality: uncertain

5210. Nutritional and Environmental Approaches to Preventing and Treating Autism and Attention Deficit Hyperactivity Disorder (ADHD): A Review. Full Text available with Trip Pro

Nutritional and Environmental Approaches to Preventing and Treating Autism and Attention Deficit Hyperactivity Disorder (ADHD): A Review. The purpose of this study was to concisely review the available literature of nutritional and environmental factors on autistic spectrum and attention deficit hyperactivity disorder (ADHD).Review of journal articles found on the PubMed database and from information from several conference proceedings.Many, but not all, studies link exposure to toxins (...) disorders and ADHD are complicated conditions in which nutritional and environmental factors play major roles. Larger studies are needed to determine optimum multifactorial treatment plans involving nutrition, environmental control,medication, and behavioral/education/speech/physical therapies.

2008 Journal of Alternative and Complementary Medicine

5211. Exercise responses in boys with attention deficit/hyperactivity disorder: effects of stimulant medication. (Abstract)

Exercise responses in boys with attention deficit/hyperactivity disorder: effects of stimulant medication. The effect of stimulant medication on exercise responses was studied in 14 boys (10.9 +/- 1.1 years) with attention deficit/hyperactivity disorder (ADHD).Exercise, with and without medication, was performed at 25 W, 50 W, and 75 W, followed by a peak exercise test.Submaximal heart rate (HR) was significantly higher by ~8 to 13 b.min(-1) across the three intensities during the medication (...) exercise are attenuated in some but not all boys with ADHD.

2008 Journal of attention disorders

5212. Atomoxetine Versus Placebo for Symptoms of Attention-Deficit/Hyperactivity Disorder (ADHD) in Children and Adolescents With Autism Spectrum Disorder

table for MeSH terms Disease Attention Deficit Disorder with Hyperactivity Hyperkinesis Autism Spectrum Disorder Autistic Disorder Pathologic Processes Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders Dyskinesias Neurologic Manifestations Nervous System Diseases Signs and Symptoms Child Development Disorders, Pervasive Atomoxetine Hydrochloride Adrenergic Uptake Inhibitors Neurotransmitter Uptake Inhibitors Membrane Transport Modulators Molecular (...) Atomoxetine Versus Placebo for Symptoms of Attention-Deficit/Hyperactivity Disorder (ADHD) in Children and Adolescents With Autism Spectrum Disorder Atomoxetine Versus Placebo for Symptoms of Attention-Deficit/Hyperactivity Disorder (ADHD) in Children and Adolescents With Autism Spectrum Disorder - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved

2006 Clinical Trials

5213. Behavior in Children With Attention Deficit Hyperactivity Disorder and in Healthy Volunteers

for the assessment). Participants in the MRI study will also have physical examinations and blood and urine tests. All children will undergo intelligence tests; and those with ADHD will have tests to confirm the diagnosis. The parents of child participants will complete an autism screening questionnaire. Condition or disease Attention Deficit Hyperactivity Disorder Detailed Description: The inability to exert appropriate inhibitory control over one's behavior is an important symptom of many psychiatric illnesses (...) Institute of Mental Health (NIMH) Information provided by (Responsible Party): National Institutes of Health Clinical Center (CC) ( National Institute of Mental Health (NIMH) ) Study Details Study Description Go to Brief Summary: The purpose of this study is to determine how the brain controls motor activity in children with attention deficit hyperactivity disorder (ADHD). The inability to control one s behavior is an important symptom of many psychiatric illnesses. The stop signal paradigm which

2001 Clinical Trials

5214. An open trial of pemoline in drug-dependent delinquents with attention-deficit hyperactivity disorder. (Abstract)

An open trial of pemoline in drug-dependent delinquents with attention-deficit hyperactivity disorder. Adolescents with conduct disorder and substance use disorders have high rates of comorbid attention-deficit hyperactivity disorder (ADHD); ADHD may contribute to the severity and persistence of substance use disorders and antisocial behaviors. Treatment of ADHD may help patients utilize substance and other behaviorally focused treatment. Yet little is known about the response of ADHD symptoms (...) to psychopharmacological intervention in substance-dependent delinquents.Pilot data are presented for 13 male adolescents with conduct disorder, substance use disorders, and ADHD, in a residential substance use treatment program. Patients were treated with pemoline. Scores from the Conners Hyperactivity Index and continuous performance tasks were obtained at baseline and after about 1 month of treatment with pemoline. Physical activity measurements were also assessed at baseline and 1 month. Postmedication assessments

1996 Journal of the American Academy of Child and Adolescent Psychiatry

5215. A randomized, double-blind, placebo-controlled, parallel-group study of SLI381 (Adderall XR) in children with attention-deficit/hyperactivity disorder. (Abstract)

A randomized, double-blind, placebo-controlled, parallel-group study of SLI381 (Adderall XR) in children with attention-deficit/hyperactivity disorder. SLI381 (Adderall XR) is a 2-component extended-release capsule formulation of Adderall designed to produce a therapeutic effect that lasts throughout the day with 1 morning dose. The primary objective of this study was to assess the efficacy and safety of SLI381 compared with placebo in the treatment of attention-deficit/hyperactivity disorder (...) the study. Physical examinations and electrocardiograms were performed at the screening and the end of the study.Five hundred eighty-four children were randomized, 563 were included in the intent-to-treat population, and 509 completed the entire study. Intention-to-treat analysis of Conners Global Index Scale for Teachers and Conners Global Index Scale for Parents scores revealed significant improvement in morning, afternoon, and late afternoon behavior for all active treatment groups versus placebo

2002 Pediatrics Controlled trial quality: predicted high

5216. Attention deficit/hyperactivity disorder and psychopharmacologic treatments in the athlete. (Abstract)

Attention deficit/hyperactivity disorder and psychopharmacologic treatments in the athlete. It is conjectured that attention deficit/hyperactivity disorder (ADHD) symptoms adversely impacting academics, family functioning, social relationships, and vocational performance might also negatively affect athletic and sport performance and enjoyment; this warrants further scientific inquiry. Children, adolescents, and adults participate in organized and impromptu sport activities, both team (...) and individual. With the concern about an epidemic of obesity in the United States, barriers to participation in sport and exercise such as ADHD need to be better understood. This article approaches ADHD in sports by providing a brief introduction to ADHD, first reviewing general clinical findings, then discussing recreational youth sports and psychopharmacological treatment risks and benefits for the elite athlete.

2005 Clinics in Sports Medicine

5217. Use of primary and secondary reinforcers after performance of a 1 mile walk/run by boys with attention deficit hyperactivity disorder. (Abstract)

Use of primary and secondary reinforcers after performance of a 1 mile walk/run by boys with attention deficit hyperactivity disorder. Based on visual inspection of time (sec.) across 8 exercise sessions for each, 3 reinforcement techniques of mainly token exchange and verbal praise paired with token exchange, were mildly associated with improvement of the cardiovascular performances of 5 young boys with ADHD. Specific reinforcement techniques improved time for this 1-mile walk/run by 5 boys (...) with ADHD.

2001 Perceptual and motor skills Controlled trial quality: uncertain

5218. The effects of exercise on children with attention-deficit hyperactivity disorder. (Abstract)

The effects of exercise on children with attention-deficit hyperactivity disorder. The effects of exercise on children with attention-deficit hyperactivity disorder (ADHD) were evaluated by studying the rate of spontaneous eye blinks, the acoustic startle eye blink response (ASER), and motor impersistence among 8- to 12-yr-old children (10 boys and 8 girls) meeting DSM-III-R criteria for ADHD.Children ceased methylphenidate medication 24 h before and during each of three daily conditions (...) maximal exercise. Girls with ADHD had increased ASER amplitude and decreased ASER latency after submaximal exercise.The findings suggest an interaction between sex and exercise intensity that is not explained by physical fitness, activity history, or selected personality attributes. The clinical meaning of the eye blink results is not clear, as improvements in motor impersistence occurred only for boys after maximal exercise. Nonetheless, these preliminary findings are sufficiently positive

2002 Medicine and science in sports and exercise

5219. The Effects of Massage Therapy & Exercise Therapy on Children/Adolescents with Attention Deficit Hyperactivity Disorder Full Text available with Trip Pro

The Effects of Massage Therapy & Exercise Therapy on Children/Adolescents with Attention Deficit Hyperactivity Disorder 19030480 2011 07 14 2018 11 13 1716-9119 12 2 2003 Mar The Canadian child and adolescent psychiatry review = La revue canadienne de psychiatrie de l'enfant et de l'adolescent Can Child Adolesc Psychiatr Rev The effects of massage therapy & exercise therapy on children/adolescents with attention deficit hyperactivity disorder. 40-3 Maddigan Barbara B Hodgson Pamela P Heath

2003 The Canadian child and adolescent psychiatry review

5220. Catecholamine response to exercise in children with attention deficit hyperactivity disorder. Full Text available with Trip Pro

Catecholamine response to exercise in children with attention deficit hyperactivity disorder. The objective of this study was to examine differences in catecholamine (CA) response to exercise between children who had received a diagnosis of attention-deficit/hyperactivity disorder (ADHD) and age- and gender-matched controls. On the basis of the notion of a CA dysfunction in ADHD, we reasoned that the normal robust increase in circulating CA seen in response to exercise would be blunted (...) in children with ADHD. To test this, we recruited 10 treatment-naïve children with newly diagnosed ADHD and 8 age-matched controls (all male) and measured CA response to an exercise test in which the work was scaled to each subject's physical capability. After exercise, epinephrine and norepinephrine increased in both control and ADHD subjects (p = 0.006 and p = 0.002, respectively), but the responses were substantially blunted in the ADHD group (p = 0.018) even though the work performed did not differ

2003 Pediatric Research

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