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5101. Evaluation and Follow-up of Individuals With Obsessive-Compulsive Disorder and Related Conditions

), connective tissue disorders, but must show no other serious or acute medical illnesses as determined by a physical exam and standard laboratory examinations. Individuals must be at least 18 years old. EXCLUSION CRITERIA: Alcohol or substance use or dependence of sufficient magnitude to require independent, concurrent treatment intervention (e.g., antabuse or opiate treatment, but not including self-help groups). Current history of aggressive behavior or current suicidal ideation with plan and intent (...) Evaluation and Follow-up of Individuals With Obsessive-Compulsive Disorder and Related Conditions Evaluation and Follow-up of Individuals With Obsessive-Compulsive Disorder and Related Conditions - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove

2000 Clinical Trials

5102. An experiment on cognitive remediation of word-reading difficulty. (Abstract)

An experiment on cognitive remediation of word-reading difficulty. Cognitive remediation of decoding deficit was attempted by following a theoretically based program. The theory identifies four major cognitive processes: Planning, Attention, Simultaneous, and Successive (PASS) processing. The PASS Remedial Program (PREP) provides 10 structured tasks that are aimed at developing internalized strategies for mainly successive processes (6 tasks) and simultaneous process (4 tasks); deficits (...) in either of the two may lead to poor decoding. Through its "global process" training and curriculum-related "bridging" training, PREP facilitates application of internalized strategies arrived at inductively for learning word decoding and spelling; it does not provide direct teaching of rules or exercises. To test the efficacy of PREP, we divided 51 children with decoding difficulties in Grade 4 into two groups: PREP (both global and bridging) and no treatment. In the second part of the study, children

1995 Journal of learning disabilities Controlled trial quality: uncertain

5103. Methylphenidate in hyperactive boys with comorbid tic disorder: II. Short-term behavioral effects in school settings. (Abstract)

Methylphenidate in hyperactive boys with comorbid tic disorder: II. Short-term behavioral effects in school settings. In this study, 11 prepubertal hyperactive boys with tic disorder received placebo and three doses of methylphenidate (0.1, 0.3, and 0.5 mg/kg) for 2 weeks each, under double-blind conditions. Each boy was observed for approximately 20 hours in the school setting (classroom seatwork activities, lunchroom, and playground). Results showed that methylphenidate effectively suppressed (...) hyperactive/disruptive behaviors in the classroom and physical aggression in the lunchroom and on the playground. Methylphenidate also reduced the occurrence of vocal tics in the classroom and the lunchroom. None of the motor tic measures revealed drug effects, but the lowest mean rate of motor tics occurred on the 0.3 mg/kg dose. On an operationally defined minimal effective dose, only one boy experienced motor tic exacerbation.

1992 Journal of the American Academy of Child and Adolescent Psychiatry Controlled trial quality: uncertain

5104. Cognitive remediation of working memory deficits: durability of training effects in severely impaired and less severely impaired schizophrenia. (Abstract)

Cognitive remediation of working memory deficits: durability of training effects in severely impaired and less severely impaired schizophrenia. To determine whether augmenting work therapy (WT) with neurocognitive enhancement therapy (NET) yields greater improvement in working memory performance than WT alone and whether there is an interaction with severity of impairment.A total of 102 participants with schizophrenia or schizoaffective disorder were categorized as severely or less severely (...) cognitively impaired and randomly assigned to receive NET + WT or WT alone. NET consisted of cognitive training exercises in attention, memory, executive function, and social information processing, and WT was a 6-month work program.Comparison on Digits Backwards from intake to follow-up revealed significantly greater improvement for participants receiving NET + WT, but there was no interaction with severity group. Follow-up 6 months after training showed that training effects endured.NET + WT improved

2003 Acta Psychiatrica Scandinavica Controlled trial quality: uncertain

5105. Effects of the home environmental skill-building program on the caregiver-care recipient dyad: 6-month outcomes from the Philadelphia REACH Initiative. (Abstract)

, of whom 190 participated in a follow-up interview. Caregivers were randomized to a usual care control group or intervention group that received five home contacts and one telephone contact by occupational therapists, who provided education, problem-solving training, and adaptive equipment. Baseline and 6-month follow-up included self-report measures of caregiver objective and subjective burden, caregiver well-being, and care recipient problem behaviors and physical function.Compared with controls (n (...) = 101), intervention caregivers (n = 89) reported less upset with memory-related behaviors, less need for assistance from others, and better affect. Intervention spouses reported less upset with disruptive behaviors; men reported spending less time in daily oversight; and women reported less need for help from others, better affect, and enhanced management ability, overall well-being, and mastery relative to control group counterparts. Statistically significant treatment differences were not found

2003 The Gerontologist Controlled trial quality: uncertain

5106. Characteristics and problems of 600 adolescent cannabis abusers in outpatient treatment. (Abstract)

the DSM-IV criteria for substance dependence, while 50% met criteria for a diagnosis of abuse. Only 20% of the participants perceived any need for help with problems associated with their drug or alcohol use. Clients participating in the study typically presented multiple problems at treatment entry, most often including conduct disorder, attention deficit hyperactivity disorder (ADHD), internal (mental) distress, and physical health distress. The co-occurrence of conduct disorder and ADHD was found (...) , with the remaining 4% having at least one symptom of dependence plus significant problems indicating need for treatment.The Global Appraisal of Individual Needs (GAIN) was used to collect the information presented in this paper. The GAIN incorporates DSM-IV criteria for substance use disorders, conduct disorder and attention deficit hyperactivity disorder, as well as dimensional (scale) measures for physical and mental health.All participants reported at least one symptom of substance use disorders, and 46% met

2002 Addiction (Abingdon, England) Controlled trial quality: uncertain

5107. Neurocognitive enhancement therapy with work therapy: effects on neuropsychological test performance. (Abstract)

Neurocognitive enhancement therapy with work therapy: effects on neuropsychological test performance. Cognitive deficits are a major determinant of social and occupational dysfunction in schizophrenia. In this study, we determined whether neurocognitive enhancement therapy (NET) in combination with work therapy (WT) would improve performance on neuropsychological tests related to but different from the training tasks.Sixty-five patients with schizophrenia or schizoaffective disorder were (...) randomly assigned to NET plus WT or WT alone. Neurocognitive enhancement therapy included computer-based training on attention, memory, and executive function tasks; an information processing group; and feedback on cognitive performance in the workplace. Work therapy included paid work activity in job placements at the medical center (eg, mail room, grounds, library) with accompanying supports. Neuropsychological testing was performed at intake and 5 months later.Prior to enrollment, both groups did

2001 Archives of general psychiatry Controlled trial quality: uncertain

5108. The behavioral impact of growth hormone treatment for children and adolescents with Prader-Willi syndrome: a 2-year, controlled study. (Abstract)

Disorders, Fourth Edition categories: Depression, Obsessive-Compulsive Disorder, Anxiety Disorder, Somatization Disorder, Conduct Disorder, and Attention-Deficit/Hyperactivity Disorder. The SDI was modified to include 10 items specifically inquiring about PWS (eg, denies having PWS, picks excessively at skin, nose, or other body parts). Because diagnoses are not mutually exclusive, an individual can meet criteria for 1 or more diagnostic categories. The SDI contains a second section measuring behavior (...) #15q. Morbid obesity resulting from hyperphagia is amplified by decreased energy expenditure and reduced physical activity. The hyperphagia has proven refractory to all psychopharmocologic intervention; the behavioral components are equally resistant to psychotropic intervention. PWS patients' body composition resembles that of individuals with growth hormone (GH) deficiency, including short stature and reduced lean body mass with concomitant increased fat mass. We hypothesized that GH

2002 Pediatrics Controlled trial quality: uncertain

5109. Functional disability and school activity limitations in 41,300 school-age children: relationship to medical impairments. (Abstract)

included 4.1% needing or receiving special education, 0.7% unable to attend, and 0.9% limited attendance. We categorized International Classification of Diseases, Ninth Revision impairment codes reported in conjunction with medical usage as physical disorders (n = 1251; eg, leukemia, diabetes), asthma (n = 916), neurodevelopmental disorders (n = 802; eg, cerebral palsy, epilepsy, mental retardation, autism, blindness, deafness), and learning-behavior disorders (n = 806; eg, attention-deficit (...) /hyperactivity disorder, learning disability, anxiety) for children with functional or school activity limitations. Of children with multiple functional disabilities, 29.9% had neurodevelopmental disorders, 27.1% had learning-behavior disorders, 18.1% had physical disorders, 4.2% had asthma, and 20.8% did not have an identified medical impairment because they had not received medical services in the past year. Among children requiring special education, physical disorders accounted for 9.4

2003 Pediatrics

5110. National estimates of health services expenditures for children with behavioral disorders: an analysis of the medical expenditure panel survey. (Abstract)

National estimates of health services expenditures for children with behavioral disorders: an analysis of the medical expenditure panel survey. Children with attention-deficit/hyperactivity disorder and asthma incur similar health care costs that are greater than those of most children without these conditions. Preliminary findings suggest that children with emotional behavioral disorders, anxiety and depression, incur even greater costs.To determine if children with behavioral disorders have (...) similar health services expenditures as children with physical conditions and to assess whether children with emotional behavioral disorders incur greater expenditures than children with disruptive behavioral disorders.Children 2 to 18 years old who were members of households participating in the 1996 Medical Expenditure Panel Survey were eligible for this retrospective cohort study. Children with common behavioral disorders selected a priori were identified by using truncated International

2003 Pediatrics

5111. Cost-effectiveness of methylphenidate versus AMP/DEX mixed slats for the first-line treatment of ADHD

, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of methylphenidate (MPH) versus amphetamine/dextroamphetamine mixed salts (AMP/DEX) as first-line agents for the treatment of attention deficit hyperactivity disorder (ADHD) was studied. Type of intervention Treatment. Economic study type Cost-utility analysis. Study population The study population comprised a hypothetical cohort of male children aged (...) in the review No study designs were reported. However, the studies used to assess efficacy rates included those that assessed response to therapy at a minimum of 1 month and a maximum of 8 weeks. Sources searched to identify primary studies HealthSTAR and MEDLINE were searched for primary studies using the keywords "attention deficit hyperactivity disorder", "methylphenidate", "amphetamine / dextroamphetamine mixed salts", "adverse events", "compliance rates", "school administration", "economic burden

2004 NHS Economic Evaluation Database.

5112. Exercise to Improve Self?Esteem in Children and Young People Full Text available with Trip Pro

DISORDER∗) ADHD (ATTENTION next DEFICIT) (DISRUPTIVE near (BEHAVIOR or BEHAVIOUR)) HYPERACTIV∗ (CONDUCT near DISORDER∗) ((BEHAVIOR or BEHAVIOUR) next DISORDER∗) (TIC near DISORDER∗) (TOURETTE∗ next SYNDROME) (MOOD∗ near DISORDER∗) (AFFECTIVE next SYMPTOM∗) AGGRESS∗ DEPRESS∗ (((((((((((((((((#23 or #24) or #25) or #26) or #27) or #28) or #29) or #30) or #31) or #32) or #33) or #34) or #35) or #36) or #37) or #38) or #39) or #40) (DYSTHYMIC next DISORDER∗) ((SEASONAL next AFFECTIVE) next DISORDER (...) ‐DEFICIT‐AND‐DISRUPTIVEBEHAVIOR‐DI∗:ME AFFECTIVE‐SYMPTOMS∗:ME AGGRESSION∗:ME DEPRESSION∗:ME SELF‐INJURIOUS‐BEHAVIOR∗:ME STRESS‐PSYCHOLOGICAL∗:ME EMOTIONS∗:ME MENTAL‐COMPETENCY∗:ME ADAPTATION‐PSYCHOLOGICAL∗:ME PERSONALITY‐DEVELOPMENT∗:ME BODY‐IMAGE∗:ME MENTAL‐HEALTH∗:ME ((((((((((((#9 or #10) or #11) or #12) or #13) or #14) or #15) or #16) or #17) or #18) or #19) or #20) or #21) (MENTAL∗ next DISORDER∗) (ADJUSTMENT∗ next DISORDER∗) (ANXIETY next DISORDER∗) (PHOBIC near DISORDER∗) PHOBI∗ (STRESS next

2005 Campbell Collaboration

5113. Should children with ADHD and normal intelligence be routinely screened for underlying cytogenetic abnormalities?

the diagnostic criteria for attention deficit hyperactivity disorder (ADHD). There is no evidence of developmental delay, dysmorphism, or other physical abnormalities and no relevant family history. Parents are keen on investigation for a "cause" for his problems. You are aware that some chromosomal and cytogenetic abnormalities may be associated with ADHD. You wonder if you should check karyotype and look for cytogenetic abnormalities with genetic implications for the family. Search Strategy OVID Medline (...) -deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry 2002;41:806–10. Gothelf D, Presburger G, Levy D, et al. Genetic, developmental, and physical factors associated with attention deficit hyperactivity disorder in patients with velocardiofacial syndrome. Am J Med Genet B Neuropsychiatr Genet . 2004;126:116–21. Boycott KM, Parslow MI, Ross JL, et al. A familial contiguous gene deletion syndrome at Xp22.3 characterized by severe learning disabilities and ADHD. Am J Med Genet A 2003;122:139

2006 BestBETS

5114. The experiences of children and adolescents living with ADHD were reflected in 6 themes Full Text available with Trip Pro

Slimmer , RN, PhD Statistics from Altmetric.com Kendall J, Hatton D, Beckett A, et al . Children’s accounts of attention-deficit/hyperactivity disorder. ANS Adv Nurs Sci 2003 ; 26 : 114 –30. Q What are the experiences of children and adolescents living with attention deficit hyperactivity disorder (ADHD)? DESIGN Qualitative study. SETTING Portland, Oregon and San Diego, California, USA. PATIENTS 39 children and adolescents with ADHD (age range 6–17 y; 67% boys; 38% African-American, 33% Hispanic (...) “weird” or “whacko.” CONCLUSION The experiences of children and adolescents with attention deficit hyperactivity disorder (ADHD) were reflected in 6 themes: problems in thinking, behaving, and feeling; meaning and identity; taking pills; the importance of Mom; causes of ADHD; and differences associated with ethnicity or race. Commentary More children are referred to mental health clinics for ADHD than for any other psychiatric or behavioural problem. The qualitative study by Kendall et al provides

2005 Evidence-Based Nursing

5115. Children and physical activity: a systematic review of barriers and facilitators

. All five studies examined children’s views on what stopped them taking part in physical activity. These studies highlighted a total of 20 distinct but interrelated barriers. The 20 barriers clustered around three underlying themes: preferences and priorities (e.g. a preference for doing other things, a lack of spare time); family life and parental support (e.g. parents’ lack of current participation in, or enthusiasm for, sports and exercise); restricted access to opportunities for participation (...) in sport or exercise (e.g. cost, particularly for children from families with a low income; distance, particular for children from rural areas; lack of means for safe travel; lack of facilities) and participating in unstructured forms of physical activity (e.g. busy traffic; threat of crime; threat of intimidation by older children; and neglect of local play areas). Four of the five studies also examined children’s views about what helped them to take part in physical activity. A total of 14 distinct

2003 EPPI Centre

5116. Antecedent exercise in the treatment of disruptive behavior: a meta-analytic review

unclear) using the following search terms and cross-references: 'exercise', 'physical activity', 'running', 'jogging' with 'behavior', 'conduct' and 'hyperactivity'. The National Technical Information Service (NTIS, 1989) was also searched. An ancestry analysis was conducted on each report located. Dissertation Abstracts International database, and convention programmes from the Association for Behavior Analysis (1989 to 1992) and the Association for the Advancement of Behavior Therapy (1989 to 1992 (...) : 'an adequate number of observations, regular reliability checks on the dependent variable, regular treatment integrity checks on the independent variable, appropriate control groups or conditions incorporating attention placebos, assessment of the social validity of treatment outcomes and whenever possible blinding of as many persons as possible'. Bibliographic details Allison D B, Faith M S, Franklin R D. Antecedent exercise in the treatment of disruptive behavior: a meta-analytic review. Clinical

1995 DARE.

5117. Effectiveness of Lobeline in Treating Symptoms of ADHD in Adult Patients

Attention Deficit Disorder with Hyperactivity Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders Methylphenidate Dopamine Lobeline Central Nervous System Stimulants Physiological Effects of Drugs Dopamine Uptake Inhibitors Neurotransmitter Uptake Inhibitors Membrane Transport Modulators Molecular Mechanisms of Pharmacological Action Dopamine Agents Neurotransmitter Agents Cardiotonic Agents Sympathomimetics Autonomic Agents Peripheral Nervous System Agents (...) (NIMH) Information provided by (Responsible Party): Yaupon Therapeutics Study Details Study Description Go to Brief Summary: The study will evaluate the effectiveness of the nonstimulant medication lobeline in improving symptoms of attention deficit hyperactivity disorder in adults. Condition or disease Intervention/treatment Phase Attention Deficit Disorder With Hyperactivity Drug: Lobeline sulfate Drug: Methylphenidate HCl Drug: Placebo Phase 2 Detailed Description: Attention deficit hyperactivity

2008 Clinical Trials

5118. Effectiveness of a Electroencephalogram (EEG) Biofeedback for the Treatment of ADHD

Brain-Computer Interface System Additional relevant MeSH terms: Layout table for MeSH terms Attention Deficit Disorder with Hyperactivity Hyperkinesis Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders Dyskinesias Neurologic Manifestations Nervous System Diseases Signs and Symptoms (...) , Singapore Collaborators: Institute for Infocomm Research Duke-NUS Graduate Medical School Information provided by (Responsible Party): Lim Choon Guan, National Healthcare Group, Singapore Study Details Study Description Go to Brief Summary: The aim of this study is to investigate if electroencephalogram (EEG) biofeedback incorporating the use of video games is effective in improving inattentive symptoms in children with ADHD. Condition or disease Intervention/treatment Phase Attention Deficit

2008 Clinical Trials

5119. Treatment of Children With ADHD Who do Not Fully Respond to Stimulants

resistant Partial responder Non-responder Atypical Antipsychotic Additional relevant MeSH terms: Layout table for MeSH terms Attention Deficit Disorder with Hyperactivity Hyperkinesis Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders Dyskinesias Neurologic Manifestations Nervous System Diseases Signs and Symptoms Aripiprazole Central Nervous System Stimulants Antidepressive Agents Psychotropic Drugs Antipsychotic Agents Tranquilizing Agents Central Nervous (...) or disease Intervention/treatment Phase Attention Deficit Hyperactivity Disorder Drug: aripiprazole Phase 2 Detailed Description: We propose to do this with a single site, ten week, pilot study of 40 school age children, ages 6-17, with Attention-Deficit/ Hyperactivity Disorder (ADHD) and moderate or greater impairment (C-GAS < 55) who show ADHD symptoms despite a trial in the community with their primary care practitioner with either of two of the most commonly used stimulants (i.e., either OROS-MPH

2006 Clinical Trials

5120. Pilot Study of Vyvanseâ„¢ In ADHD Adolescents at Risk for Substance Abuse

Psychiatric Institute: Attention Deficit Hyperactivity Disorder ADHD ADD Prevention Substance use Adolescent Additional relevant MeSH terms: Layout table for MeSH terms Attention Deficit Disorder with Hyperactivity Hyperkinesis Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders Dyskinesias Neurologic Manifestations Nervous System Diseases Signs and Symptoms Lisdexamfetamine Dimesylate Central Nervous System Stimulants Physiological Effects of Drugs Dopamine (...) to study and treat high risk youth before they develop substance abuse. Condition or disease Intervention/treatment Phase Attention Deficit Hyperactivity Disorder Drug: Vyvanse Phase 4 Detailed Description: The study is a six month open-label treatment with Vyvanse, a novel preparation of the Attention Deficit Hyperactivity Disorder (ADHD) medication dextroamphetamine in which the drug is inactivated and only becomes reactivated when digested. Vyvanse is thought to be safer in youth at risk

2007 Clinical Trials

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