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121. Attention Deficit Hyperactivity Disorder (Overview)

multiple outcome domains. J Am Acad Child Adolesc Psychiatry . 2014 Aug. 53(8):835-847.e5. . Brauser D. Behavioral interventions effective for ADHD. Medscape Medical News . July 31, 2014. . Spinelli S, Joel S, Nelson TE, Vasa RA, Pekar JJ, Mostofsky SH. Different neural patterns are associated with trials preceding inhibitory errors in children with and without attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry . 2011 Jul. 50(7):705-715.e3. . Ducharme S, Hudziak JJ, Botteron (...) Psychologist, The Affinity Center Christine A Mayhall, PhD is a member of the following medical societies: Disclosure: Nothing to disclose. Mary L Windle, PharmD Adjunct Associate Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference Disclosure: Nothing to disclose. What would you like to print? What would you like to print? Sections Pediatric Attention Deficit Hyperactivity Disorder (ADHD) Find Us On About Membership WebMD Network Editions All

2014 eMedicine Pediatrics

122. Attention Deficit Hyperactivity Disorder (Diagnosis)

multiple outcome domains. J Am Acad Child Adolesc Psychiatry . 2014 Aug. 53(8):835-847.e5. . Brauser D. Behavioral interventions effective for ADHD. Medscape Medical News . July 31, 2014. . Spinelli S, Joel S, Nelson TE, Vasa RA, Pekar JJ, Mostofsky SH. Different neural patterns are associated with trials preceding inhibitory errors in children with and without attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry . 2011 Jul. 50(7):705-715.e3. . Ducharme S, Hudziak JJ, Botteron (...) Psychologist, The Affinity Center Christine A Mayhall, PhD is a member of the following medical societies: Disclosure: Nothing to disclose. Mary L Windle, PharmD Adjunct Associate Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference Disclosure: Nothing to disclose. What would you like to print? What would you like to print? Sections Pediatric Attention Deficit Hyperactivity Disorder (ADHD) Find Us On About Membership WebMD Network Editions All

2014 eMedicine Pediatrics

123. The efficacy of cognitive-behavioral therapy for older adults with ADHD: a randomized controlled trial. (Abstract)

The efficacy of cognitive-behavioral therapy for older adults with ADHD: a randomized controlled trial. Older adults with ADHD exhibit significant functional impairment, yet there is little research to guide clinicians in evidence-based care of these adults. This study examined response to treatment in older adults who participated in a previous study of the efficacy of cognitive-behavioral treatment (CBT) in adult ADHD. It was hypothesized that older adults would respond less well to CBT than (...) younger adults, given the cognitive demands of the treatment. As described in the original publication, 88 adults who met DSM-IV criteria for ADHD were randomized to receive either a manualized 12-week CBT group intervention targeting executive dysfunction or a parallel Support group. In the current study, outcomes for 26 adults, aged 50 or older, were compared with those of 55 younger adults with respect to inattentive symptoms assessed on a structured interview by a blind clinician, as well

2018 Attention deficit and hyperactivity disorders Controlled trial quality: uncertain

124. Third Generation Cognitive Behavioural Therapy vs Treatment-as-usual for ADHD

results. Condition or disease Intervention/treatment Adhd Behavioral: Mindfulness Cognitive Behavioral Therapy program Study Design Go to Layout table for study information Study Type : Observational Estimated Enrollment : 744 participants Observational Model: Cohort Time Perspective: Prospective Official Title: Third Generation Cognitive Behavioural Therapy Versus Treatment-as-usual for Attention Deficit and Hyperactivity Disorder: a Randomized, 2-parallel-group, Evaluator Blinded, Superiority Trial (...) Update Posted : August 2, 2018 See Sponsor: Centre Hospitalier Universitaire de Nīmes Information provided by (Responsible Party): Centre Hospitalier Universitaire de Nīmes Study Details Study Description Go to Brief Summary: The investigators hypothesize that the mindfulness Cognitive Behavioral Therapy program will lead to a reduction in attention deficit and hyperactivity disorder symptoms, anxiety and depression, and improve self-confidence, emotional control, social integration and school

2018 Clinical Trials

125. An Exploratory, Single-Blind Pilot Study Of Flexible Doses of the Triple Reuptake Inhibitor EB-1020 SR in the Treatment of Adult Males With Attention-Deficit Hyperactivity Disorder

: Neurovance, Inc. ClinicalTrials.gov Identifier: Other Study ID Numbers: EB-1020-SR-ADHD-201 First Posted: September 11, 2013 Last Update Posted: November 5, 2015 Last Verified: September 2015 Keywords provided by Euthymics BioScience, Inc. ( Neurovance, Inc. ): Adult ADHD Additional relevant MeSH terms: Layout table for MeSH terms Attention Deficit Disorder with Hyperactivity Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders (...) Of Flexible Doses of the Triple Reuptake Inhibitor EB-1020 SR in the Treatment of Adult Males With Attention-Deficit Hyperactivity Disorder Study Start Date : September 2013 Actual Primary Completion Date : February 2014 Actual Study Completion Date : February 2014 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: EB-1020 SR 100-500 mg flexible titration Drug: EB-1020 SR 100-500 mg flexible titration Placebo

2013 Clinical Trials

126. The Effect of Physical Training and the Omega 3 Consumption on Attention Deficit Hyperactivity Disorder in Children

Numbers: ADHD_Omega_Exercise First Posted: March 8, 2013 Last Update Posted: March 8, 2013 Last Verified: March 2013 Keywords provided by JGalduroz, Federal University of São Paulo: Physical Training ADHD-Attention deficit hyperactivity disorder Omega 3 Additional relevant MeSH terms: Layout table for MeSH terms Attention Deficit Disorder with Hyperactivity Hyperkinesis Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders Dyskinesias Neurologic (...) a placebo of fish oil. Behavioral and cognitive functions evaluations and blood analysis will be made at the beginning and at the end of the protocol. Condition or disease Intervention/treatment Phase Attention Deficit Hyperactivity Disorder Dietary Supplement: Omega 3 Other: Physical Training Phase 3 Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 68 participants Allocation: Randomized Intervention Model: Parallel Assignment

2013 Clinical Trials

127. The Effect of Methylphenidate Versus Placebo on State Anxiety in Children With Attention Deficit Hyperactivity Disorder.

ClinicalTrials.gov Identifier: Other Study ID Numbers: 0009-12-SHA First Posted: February 25, 2013 Last Update Posted: March 23, 2015 Last Verified: March 2015 Keywords provided by Maya Kritchman Lupo, Shalvata Mental Health Center: Attention Deficit Hyperactivity Disorder Methylphenidate Placebo State anxiety Additional relevant MeSH terms: Layout table for MeSH terms Disease Attention Deficit Disorder with Hyperactivity Hyperkinesis Pathologic Processes Attention Deficit and Disruptive Behavior Disorders (...) will receive either methylphenidate or placebo based on what was given on the first day of the study and they will complete the same task. Condition or disease Intervention/treatment Phase Attention Deficit Hyperactivity Disorder Drug: Methylphenidate Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 30 participants Allocation: Randomized Intervention Model: Crossover Assignment Masking: Quadruple (Participant, Care

2013 Clinical Trials

128. The Effects of DHA on Attention Deficit and Hyperactivity Disorder

: Other Study ID Numbers: EM-00-11 First Posted: February 21, 2013 Last Update Posted: August 31, 2015 Last Verified: August 2015 Keywords provided by Maria Nobile, IRCCS Eugenio Medea: ADHD DHA neuropsychological task fNIRS Docosahexaenoic Acid n-3 polyunsaturated fatty acid cognition behavior Additional relevant MeSH terms: Layout table for MeSH terms Disease Attention Deficit Disorder with Hyperactivity Hyperkinesis Pathologic Processes Attention Deficit and Disruptive Behavior Disorders (...) oil Phase 3 Detailed Description: The primary objective of this study is to investigate the relative efficacy and tolerability of omega-3 fatty acid supplementation, more specifically docosahexaenoic acid (DHA), in reducing attention-deficit/hyperactivity disorder (ADHD) symptoms in children. The present study is going to determine whether DHA supplementation induces modifications in fatty acid blood level and to evaluate the correlation between this possible modification and behavioral

2013 Clinical Trials

129. A Randomized Controlled Study of Cognitive Behavioral Therapy for Adults With Attention Deficit Disorder

: April 29, 2016 Sponsor: Peking University Sixth Hospital Information provided by (Responsible Party): Qiujin Qian, Peking University Sixth Hospital Study Details Study Description Go to Brief Summary: The purpose of this study is to determine whether cognitive behavioral therapy (CBT) is effective in the treatment of attention deficit and emotional, executive function and social function dysregulation due to attention deficit disorder (ADHD). Condition or disease Intervention/treatment Phase (...) Enrollment : 108 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: Triple (Participant, Investigator, Outcomes Assessor) Primary Purpose: Treatment Official Title: A Randomized Controlled Study of Cognitive Behavioral Therapy for Adults With Attention Deficit Disorder Study Start Date : October 2013 Actual Primary Completion Date : March 2016 Actual Study Completion Date : March 2016 Resource links provided by the National Library of Medicine related topics: Arms

2014 Clinical Trials

130. Appropriate prescribing of psychotropic medication for non-cognitive symptoms in people with dementia

, aggression, pacing, walking about, altered sexual behaviour, changed sleep patterns, and appetite disturbances. Non-pharmacological Interventions such as music therapy, relaxation, distraction techniques, and massage, or with cognitive and behavioural interventions, as opposed to pharmacological/medication interventions. Off label The use of medications for an unapproved indication or in an unapproved age group, dosage, or route of administration. Parkinson’s disease dementia The brain changes caused (...) Grading of Recommendations Assessment, Development and Evaluation GDG Guideline Development Group GDP Global Domestic Product MCI Mild Cognitive Impairment MHBC Ministry of Health British Columbia MHRA Medicines and Healthcare products Regulatory Agency NCEC National Clinical Effectiveness Committee NHMRC National Health and Medical Research Council NHS National Health Service NICE National Institute for Health and Care Excellence NPI Neuropsychiatric Inventory PBS Pharmaceutical Benefit Scheme PDD

2019 National Clinical Guidelines (Ireland)

131. Attention Deficit Disorder

Attention Deficit Disorder Aka: Attention Deficit Disorder , Attention Deficit Hyperactivity Disorder , ADHD , Attentional Disorders , Attention Deficit Disorder in Children From Related Chapters II. Epidemiology Diagnosed at one point in up to 11% of school children ages 4 to 17 years old (1-2 per classroom) At a given time 8.8% of school children have the diagnosis and 6.1% are on medication for Attention Deficit More commonly diagnosed in boys than girls (4 - 8:1) However girls are more often (...) deficit d'attenzione Derived from the NIH UMLS ( ) Ontology: Attention deficit hyperactivity disorder (C1263846) Definition (MEDLINEPLUS) Is it hard for your child to sit still? Does your child act without thinking first? Does your child start but not finish things? If so, your child may have attention deficit hyperactivity disorder (ADHD). Nearly everyone shows some of these behaviors at times, but ADHD lasts more than 6 months and causes problems in school, at home and in social situations. ADHD

2018 FP Notebook

132. Study Comparing Two Doses of MG01CI and Placebo in Adults With Predominantly Inattentive Attention Deficit Hyperactivity Disorder

terms Attention Deficit Disorder with Hyperactivity Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders Metadoxine Pyridoxine Alcohol Deterrents Vitamin B Complex Vitamins Micronutrients Nutrients Growth Substances Physiological Effects of Drugs (...) (Participant, Investigator) Primary Purpose: Treatment Official Title: Randomized, Double-blind, Single-center, Dose-finding Study Designed to Compare Two Doses of MG01CI (Metadoxine Extended Release) and Placebo in Adults With Predominantly Inattentive Attention Deficit Hyperactivity Disorder Study Start Date : August 2013 Actual Primary Completion Date : December 2013 Actual Study Completion Date : December 2013 Resource links provided by the National Library of Medicine related topics: Arms

2012 Clinical Trials

133. Attention-Deficit Hyperactivity Disorder Symptoms in Children and Adolescents with Sex Chromosome Aneuploidy: XXY, XXX, XYY, and XXYY Full Text available with Trip Pro

Attention-Deficit Hyperactivity Disorder Symptoms in Children and Adolescents with Sex Chromosome Aneuploidy: XXY, XXX, XYY, and XXYY Attentional problems, hyperactivity, and impulsivity have been described as behavioral features associated with sex chromosome aneuploidy (SCA). In this study, the authors compare attention-deficit hyperactivity disorder (ADHD) symptoms in 167 participants aged 6 to 20 years with 4 types of SCA (XXY n = 56, XYY n = 33, XXX n = 25, and XXYY n = 53). They also (...) evaluate factors associated with ADHD symptomatology (cognitive and adaptive scores, prenatal vs postnatal ascertainment) and describe the clinical response to psychopharmacologic medications in a subset of patients treated for ADHD.Evaluation included medical and developmental history, cognitive and adaptive functioning assessment, and parent and teacher ADHD questionnaires containing DSM-IV criteria.In the total study group, 58% (96/167) met DSM-IV criteria for ADHD on parent-report questionnaires

2012 Journal of Developmental and Behavioral Pediatrics

134. Treatment of comorbid attention-deficit/hyperactivity disorder and anxiety in children: a multiple baseline design analysis. Full Text available with Trip Pro

Treatment of comorbid attention-deficit/hyperactivity disorder and anxiety in children: a multiple baseline design analysis. The present study evaluated a 10-week psychosocial treatment designed specifically for children with attention-deficit/hyperactivity disorder (ADHD) and a comorbid anxiety disorder.Using a nonconcurrent multiple baseline design, the authors treated 8 children ages 8-12 with ADHD, combined type, and at least 1 of 3 major anxiety disorders (separation anxiety disorder (...) , generalized anxiety disorder, social phobia). The integrated treatment protocol involved parent management training for ADHD and family-based cognitive-behavioral therapy for anxiety. Pretreatment assessments included semistructured diagnostic interviews and other standardized measures to determine study eligibility. Children were randomized to 1 of 3 baseline control conditions (i.e., 2, 3, or 4 weeks) and subsequently treated in a university-based psychosocial treatment clinic. Weekly assessments

2012 Journal of Consulting and Clinical Psychology Controlled trial quality: uncertain

135. Does Melatonin improve sleep pattern in children with attention deficit hyperactivity disorder?

follow-up for only 24/107 patients (22%) Comment(s) Around 25 to 54% of children with ADHD have a sleep problem (Tjon Pian, Betancourt-Fursow). This difficulty with sleep can be exacerbated by psychostimulant medication used to treat hyperactivity, attention deficit and impulsiveness (Tjon Pian, Sangal). Conversely, it has also been shown that children with persistent sleep onset insomnia can have difficult behavioural or cognitive problems during the day (Sadeh). Therefore, it is important (...) , Starreveld JS, et al. Melatonin for treatment of sleeping disorders in children with attention deficit/hyperactivity disorder: a preliminary open label study. Eur J Pediatr 2003;162:554–5. Van der Heijden KB, Smits MG, Van Someren EJ, et al. Effect of melatonin on sleep, behavior, and cognition in ADHD and chronic sleep-onset insomnia. J Am Acad Child Adolesc Psychiatry 2007;46:233–41. Betancourt-Fursow de Jimenez YM, Jimenez-Leon JC, Jimenez-Betancourt CS. Attention deficit hyperactivity disorder

2009 BestBETS

136. Cognitive-Behavioral Therapy for Adult ADHD: A Randomized Clinical Trial in China. (Abstract)

Cognitive-Behavioral Therapy for Adult ADHD: A Randomized Clinical Trial in China. Cognitive-behavioral therapy (CBT) is effective for adult ADHD, and booster sessions may improve long-term outcome. This study was designed to investigate the effects of group CBT and its booster sessions for Chinese adult patients with ADHD.There were CBT only group ( n = 43), CBT +booster group ( n = 43), and control group with patients on the waiting list ( n = 22). The primary outcome was the score (...) of the ADHD-Rating Scale (ADHD-RS). Secondary outcomes included emotion, executive function (EF), impulsivity, self-esteem, and life quality at 12th and 24th week.At 12th week, the score of ADHD-RS, EF, and impulsivity showed significant improvement in CBT +booster group comparing with control group. At 24th week, differences between CBT only group and CBT +booster group were not significant.CBT was effective for Chinese adult patients with ADHD. Booster sessions do not appear to provide additional

2017 Journal of attention disorders Controlled trial quality: uncertain

137. A randomized controlled trial of cognitive behavioral therapy for ADHD in medication-treated adolescents. Full Text available with Trip Pro

A randomized controlled trial of cognitive behavioral therapy for ADHD in medication-treated adolescents. To test cognitive behavioral therapy (CBT) for persistent attention-deficit hyperactivity disorder (ADHD) symptoms in a sample of medication-treated adolescents.Forty-six adolescents (ages 14-18), with clinically significant ADHD symptoms despite stable medication treatment were randomly assigned to receive CBT for ADHD or wait list control in a cross-over design. Twenty-four were (...)  < .0001). Results were consistent across 100 multiple imputations (all p < .0001). There was a greater proportion of responders after CBT by parent (50% vs. 18%, p = .00) and adolescent (58% vs. 18% p = .02) report.This study demonstrates initial efficacy of CBT for adolescents with ADHD who continued to exhibit persistent symptoms despite medications.© 2016 Association for Child and Adolescent Mental Health.

2016 Journal of child psychology and psychiatry, and allied disciplines Controlled trial quality: predicted high

138. Efficacy of Cognitive Behavioral Therapy With and Without Medication for Adults With ADHD. Full Text available with Trip Pro

Efficacy of Cognitive Behavioral Therapy With and Without Medication for Adults With ADHD. Recent trials have demonstrated efficacy of cognitive behavioral therapy (CBT) in medicated adults with ADHD. Efficacy of CBT in unmedicated versus medicated adults remains mostly unknown. We evaluated the effects of group CBT alone versus combined with medication on ADHD symptoms and functional outcomes in adult patients.Eighty-eight adults with ADHD received 12 manualized group CBT sessions, accompanied (...) by individual coaching, either without ( n = 46) or with ( n = 42) medication. Treatment effects were evaluated following treatment and 3-month and 6-month follow-up using un-blinded self-report and observer ratings.CBT + medication resulted in greater improvements than CBT alone in ADHD symptoms, organizational skills, and self-esteem. Group differences diminished over follow-up, as the CBT alone group continued improving, while the combined group maintained the gains.CBT + medication outperformed CBT

2016 Journal of attention disorders Controlled trial quality: uncertain

139. A randomized controlled trial reporting functional outcomes of cognitive-behavioural therapy in medication-treated adults with ADHD and comorbid psychopathology. Full Text available with Trip Pro

A randomized controlled trial reporting functional outcomes of cognitive-behavioural therapy in medication-treated adults with ADHD and comorbid psychopathology. Studies assessing psychological treatment of attention deficit hyperactivity disorder (ADHD) in adults are increasingly reported. However, functional outcomes are often neglected in favour of symptom outcomes. We investigated functional outcomes in 95 adults with ADHD who were already treated with medication and randomized to receive (...) treatment as usual (TAU/MED) or psychological treatment (CBT/MED) using a cognitive-behavioural programme, R&R2ADHD, which employs both group and individual modalities. RATE-S functional outcomes associated with ADHD symptoms, social functioning, emotional control and antisocial behaviour were given at baseline, end of treatment and three-month follow-up. The Total composite score of these scales is associated with life satisfaction. In addition, independent evaluator ratings of clinicians who were

2016 European archives of psychiatry and clinical neuroscience Controlled trial quality: uncertain

140. Cognitive-Behavioral Therapy for a 9-Year-Old Girl With Disruptive Mood Dysregulation Disorder Full Text available with Trip Pro

with DMDD, co-occurring attention deficit hyperactivity disorder (ADHD), and a history of unspecified anxiety disorder. At the time of intake evaluation, she demonstrated three to four temper outbursts and two to three episodes of aggressive behavior per week, in addition to prolonged displays of non-episodic irritability lasting hours or days at a time. A total of 12 CBT sessions were conducted over 12 weeks and 5 follow-up booster sessions were completed over a subsequent 3-month period. Irritability (...) Cognitive-Behavioral Therapy for a 9-Year-Old Girl With Disruptive Mood Dysregulation Disorder Disruptive mood dysregulation disorder (DMDD) is a relatively new diagnosis in the field of childhood onset disorders. Characterized by both behavior and mood disruption, DMDD is a purportedly unique clinical presentation with few relevant treatment studies to date. The current case study presents the application of cognitive-behavioral therapy (CBT) for anger and aggression in a 9-year-old girl

2016 Clinical case studies

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