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101. Psychostimulants Effects on Brain Functional Connectivity in Youth With Attention Deficit Hyperactivity Disorder

: Randomized Intervention Model: Crossover Assignment Masking: Double (Participant, Investigator) Official Title: An Electroencephalography Study of the Effects of Psychostimulants on Dynamic Patterns of Cognitive Task-based Functional Connectivity in Youths With Attention Deficit Hyperactivity Disorder Study Start Date : December 2014 Estimated Primary Completion Date : December 2016 Estimated Study Completion Date : December 2017 Resource links provided by the National Library of Medicine related topics (...) Gothelf, Prof. , . 972-3-5303810 More Information Go to Layout table for additonal information Responsible Party: Sheba Medical Center ClinicalTrials.gov Identifier: Other Study ID Numbers: SHEBA-14-1351-IH-CTIL First Posted: December 17, 2014 Last Update Posted: December 17, 2014 Last Verified: December 2014 Keywords provided by Sheba Medical Center: adhd global network eeg Additional relevant MeSH terms: Layout table for MeSH terms Attention Deficit Disorder with Hyperactivity Attention Deficit

2014 Clinical Trials

102. Electroencephalogram and Attention Deficit Hyperactivity Disorder Study

This study aims to recruit 100 adult participants: 50 of which are adults diagnosed with Attention Deficit Hyperactivity Disorder and 50 healthy controls. All participants will perform a total of two tasks while connected to electroencephalogram (EEG) sensors; the first task is a resting state task and after that a cognitive challenge task (attention control). Study activity is performed in a single visit which lasts two hours. Participants will also be asked to complete some behavioral questionnaires (...) Last Verified: November 2017 Additional relevant MeSH terms: Layout table for MeSH terms Attention Deficit Disorder with Hyperactivity Hyperkinesis Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders Dyskinesias Neurologic Manifestations Nervous System Diseases Signs and Symptoms

2014 Clinical Trials

103. Role of Circadian and Homeostatic Systems in the Regulation of Wakefulness in Adult Patients With Attention Deficit Disorder With or Without Hyperactivity

Attention Deficit Disorder with Hyperactivity Hyperkinesis Pathologic Processes Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders Dyskinesias Neurologic Manifestations Nervous System Diseases Signs and Symptoms (...) objective is to compare the objective sleepiness in sleepy patients with ADHD and healthy subjects during a protocol of extended wake. It's an observational study of interventional type realized in patient with ADHD syndrome deprived of psychostimulant treatment (for 72 hours) and healthy subject, investigating the implication of the homeostatic and circadian systems in the preservation of awakening. Condition or disease Intervention/treatment Phase Attention-Deficit/Hyperactivity Disorder Other

2014 Clinical Trials

104. Efficacy of lisdexamfetamine dimesylate throughout the day in children and adolescents with attention-deficit/hyperactivity disorder: results from a randomized, controlled trial. Full Text available with Trip Pro

Efficacy of lisdexamfetamine dimesylate throughout the day in children and adolescents with attention-deficit/hyperactivity disorder: results from a randomized, controlled trial. Lisdexamfetamine dimesylate (LDX) is a long-acting, prodrug stimulant therapy for patients with attention-deficit/hyperactivity disorder (ADHD). This randomized placebo-controlled trial of an optimized daily dose of LDX (30, 50 or 70 mg) was conducted in children and adolescents (aged 6-17 years) with ADHD. To evaluate (...) statistically significant (P < 0.001) for both active treatments in all four subscales of the CPRS-R (ADHD index, oppositional, hyperactivity and cognitive). In conclusion, improvements relative to placebo in ADHD-related symptoms and behaviors in children and adolescents receiving a single morning dose of LDX or OROS-MPH were maintained throughout the day and were ongoing at the last measurement in the evening (1800 hours).

2014 European child & adolescent psychiatry Controlled trial quality: uncertain

105. Parental psychopathology in families of children with attention-deficit/hyperactivity disorder and exposed to maternal smoking during pregnancy. (Abstract)

Parental psychopathology in families of children with attention-deficit/hyperactivity disorder and exposed to maternal smoking during pregnancy. Both genetic and environmental factors have been implicated in the etiology of attention-deficit/hyperactivity disorder (ADHD). We had previously suggested that exposure to maternal smoking during pregnancy (MSDP) may be a valid basis for delineating a distinct subtype of ADHD, where children exposed to MSDP present with a more severe clinical picture (...) significantly more likely to have antisocial personality disorder, and problems with alcohol and drug abuse. Mothers had a significantly higher frequency of major depressive disorder (MDD), while fathers showed a trend for both MDD and bipolar disorder.Based on the pattern of psychopathology in parents of children exposed to MSDP, as well as earlier reports of the severe clinical, behavioral, and cognitive phenotype in these children, combined with the large body of epidemiological evidence, we propose

2014 Journal of Child Psychology and Psychiatry

106. Integrated cognitive behavioral therapy for ADHD in adult substance use disorder patients: Results of a randomized clinical trial. (Abstract)

Integrated cognitive behavioral therapy for ADHD in adult substance use disorder patients: Results of a randomized clinical trial. Attention Deficit Hyperactivity Disorder (ADHD) frequently co-occurs with Substance Use Disorders (SUDs). Standard ADHD pharmacotherapies are not effective in patients with this comorbidity and cognitive behavioral therapy (CBT) has not been tested in this population. This RCT aimed to compare the efficacy of Integrated CBT (CBT/Integrated) directed at adult ADHD (...) resulted in lower ARS scores than CBT/SUD, but the difference was not significant at the 0.05 level. For other secondary outcomes, including substance use, no significant between-group differences were present.Compared to regular SUD cognitive behavioral therapy, integrated cognitive behavioral therapy resulted in a significant extra improvement in ADHD symptoms in SUD + ADHD patients.Copyright © 2019 Elsevier B.V. All rights reserved.

2019 Drug and alcohol dependence Controlled trial quality: uncertain

107. Comparing Alliance in Two Cognitive-Behavioural Therapies for Adolescents With ADHD Using a Randomized Controlled Trial. (Abstract)

Comparing Alliance in Two Cognitive-Behavioural Therapies for Adolescents With ADHD Using a Randomized Controlled Trial. Alliance is defined as the client-therapist bond and their ability to collaborate on therapeutic activities. Treatment for adolescents with ADHD is rarely studied in terms of alliance. In this study, two cognitive-behavioral treatments (CBT; one structured treatment aimed at planning skills and one less-structured solution-focused treatment, both delivered in the style (...) of Motivational Interviewing) were compared with regard to alliance and alliance-outcome association. The influence of therapist competence on this alliance-outcome association was also evaluated. The alliance between 69 adolescents diagnosed with ADHD and their therapists was measured early in treatment, using the Therapy Process Observational Coding System for Child Psychotherapy-Alliance scale. Observer-rated therapist competence was measured using the Motivational Interviewing Treatment Integrity scale

2019 Behavior therapy Controlled trial quality: uncertain

108. Integrated Brain, Body and Social Intervention for Attention Deficit Hyperactivity Disorder (ADHD)

: January 17, 2018 Last Verified: January 2018 Keywords provided by Yale University: ADHD Executive function Inhibitory control Computer games Sports activities Good Behavior Game Additional relevant MeSH terms: Layout table for MeSH terms Disease Attention Deficit Disorder with Hyperactivity Hyperkinesis Pathologic Processes Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders Dyskinesias Neurologic Manifestations Nervous System Diseases Signs and Symptoms (...) component individualizes instruction to maximize benefit for each child. During the last year of the grant, we will be introducing a pilot study of an organizational skills training (OST) that will provide individualized parent and child training for improved executive functioning in children randomized to the OST plus home-based program. Condition or disease Intervention/treatment Phase Attention Deficit Hyperactivity Disorder (ADHD) Behavioral: IBBS Not Applicable Study Design Go to Layout table

2012 Clinical Trials

109. NWP09 in Children With Attention Deficit Hyperactivity Disorder (ADHD)

: February 3, 2016 Last Verified: January 2016 Keywords provided by Pfizer: ADHD methylphenidate extended-release Additional relevant MeSH terms: Layout table for MeSH terms Disease Attention Deficit Disorder with Hyperactivity Hyperkinesis Pathologic Processes Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders Dyskinesias Neurologic Manifestations Nervous System Diseases Signs and Symptoms Methylphenidate Central Nervous System Stimulants Physiological (...) by (Responsible Party): Pfizer Study Details Study Description Go to Brief Summary: The safety and efficacy of a chewable formulation of extended-release methylphenidate will be studied in children with ADHD Condition or disease Intervention/treatment Phase Attention Deficit Hyperactivity Disorder Drug: NWP09 Drug: Placebo Phase 3 Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 90 participants Allocation: Randomized Masking: Quadruple

2012 Clinical Trials

110. Psychological Treatment for Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)

: April 2015 Keywords provided by Viktor Kaldo, Karolinska Institutet: Cognitive Behavioral Therapy Dialectical Behavioral Therapy Group Treatment ADHD Additional relevant MeSH terms: Layout table for MeSH terms Attention Deficit Disorder with Hyperactivity Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders (...) Psychological Treatment for Adults With Attention-Deficit/Hyperactivity Disorder (ADHD) Psychological Treatment for Adults With Attention-Deficit/Hyperactivity Disorder (ADHD) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies

2012 Clinical Trials

111. Guided Self-Help for Parents of Adolescents With Attention-Deficit/Hyperactivity Disorder (ADHD)

: University of Cologne Collaborator: Eli Lilly and Company Information provided by (Responsible Party): Manfred Doepfner, University of Cologne Study Details Study Description Go to Brief Summary: Cognitive-behavioral based guided self-help for parents of adolescents with Attention-Deficit/Hyperactivity Disorder (ADHD) is investigated in a feasibility and effectiveness study. The treatment is offered under routine-care conditions of the health-care system in Germany. Practicability, treatment (...) Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment Official Title: Guided Self-Help for Parents of Adolescents With Attention-Deficit/Hyperactivity Disorder (ADHD): A Feasibility and Effectiveness Study Study Start Date : January 2012 Actual Primary Completion Date : November 2013 Actual Study Completion Date : November 2013 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment

2012 Clinical Trials

112. The Effect of Methylphenidate Treatment in Familial Attention Deficit/Hyperactivity Disorder (ADHD)

provided by Sheba Medical Center: Attention Deficit Hyperactivity Disorder (ADHD) Methylphenidate- RITALIN IR (Immediate Release) Additional relevant MeSH terms: Layout table for MeSH terms Disease Attention Deficit Disorder with Hyperactivity Hyperkinesis Psychomotor Agitation Pathologic Processes Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders Dyskinesias Neurologic Manifestations Nervous System Diseases Signs and Symptoms Psychomotor Disorders (...) : Recruiting First Posted : March 14, 2012 Last Update Posted : March 14, 2012 See Sponsor: Sheba Medical Center Information provided by (Responsible Party): Sheba Medical Center Study Details Study Description Go to Brief Summary: The purpose of this study is to investigate the familial response to Methylphenidate treatment (Ritalin IR) in two aspects: ADHD symptom's improvement and side-effects development. Condition or disease Intervention/treatment Phase Attention Deficit/Hyperactivity Disorder

2012 Clinical Trials

113. Study of Computer Attention Training Programs in Schools for Children With Attention Deficit/Hyperactivity Disorder

Intervention Model: Crossover Assignment Masking: Double (Participant, Outcomes Assessor) Primary Purpose: Treatment Official Title: Randomized Control Trial of Two Computer-Based Attention Training Programs in Schools for Children With Attention Deficit/Hyperactivity Disorder (ADHD) Study Start Date : May 2009 Actual Primary Completion Date : December 2012 Actual Study Completion Date : November 2013 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go (...) terms Disease Attention Deficit Disorder with Hyperactivity Hyperkinesis Pathologic Processes Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders Mental Disorders Dyskinesias Neurologic Manifestations Nervous System Diseases Signs and Symptoms

2012 Clinical Trials

114. Repetitive Transcranial Magnetic Stimulation in Symptoms of Attention Deficit Hyperactivity Disorder and Cognitive Function In Cocaine Addicts

Last Verified: May 2012 Keywords provided by University of Sao Paulo General Hospital: Repetitive Transcranial Magnetic Stimulation Cocaine Dependence Cocaine Addicts Attention Deficit Hyperactivity Disorder Cognitive Function Additional relevant MeSH terms: Layout table for MeSH terms Disease Attention Deficit Disorder with Hyperactivity Hyperkinesis Cocaine-Related Disorders Cognition Disorders Pathologic Processes Attention Deficit and Disruptive Behavior Disorders Neurodevelopmental Disorders (...) Assignment Masking: Double (Participant, Outcomes Assessor) Primary Purpose: Treatment Official Title: Effect of Repetitive Transcranial Magnetic Stimulation on Symptoms of Attention Deficit Hyperactivity Disorder and Cognitive Function In Cocaine Addicts Study Start Date : March 2010 Estimated Primary Completion Date : August 2012 Estimated Study Completion Date : March 2013 Resource links provided by the National Library of Medicine related topics: available for: Arms and Interventions Go to Arm

2012 Clinical Trials

115. The effects of methylphenidate on cognitive function in children with attention-deficit/hyperactivity disorder. (Abstract)

The effects of methylphenidate on cognitive function in children with attention-deficit/hyperactivity disorder. Focusing on behavioral criteria for attention-deficit/hyperactivity disorder (ADHD) diagnosis leads to considerable neuropsychological profile heterogeneity among diagnosed children, as well as variable response to methylphenidate (MPH) treatment. Documenting "cold" executive working memory (EWM) or "hot" self-regulation (SR) neuropsychological impairments could aid (...) in the differential diagnosis of ADHD subtypes and may help to determine the optimal MPH treatment dose. In this study, children with ADHD inattentive type (n = 19), combined type (n = 33), and hyperactive-impulse type (n = 4) underwent randomized controlled MPH trials; neuropsychological, behavioral, and observational data were collected to evaluate the children's responses. Those with moderate or significant baseline EWM/SR impairment showed robust MPH response, whereas response for those with lower baseline

2012 Postgraduate medicine Controlled trial quality: uncertain

116. Attention Deficit Hyperactivity Disorder (Treatment)

=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjg5MzUwLXRyZWF0bWVudA== processing > Attention Deficit Hyperactivity Disorder (ADHD) Treatment & Management Updated: Dec 26, 2018 Author: Stephen Soreff, MD; Chief Editor: Glen L Xiong, MD Share Email Print Feedback Close Sections Sections Attention Deficit Hyperactivity Disorder (ADHD) Treatment Medical Care The therapeutic approach to ADHD has been shifting. In some cases, environmental restructuring and behavioral therapy alone has been effective. Developments in behavioral parent training (BPT) and behavioral (...) Psychiatry . 2009 Dec. 166(12):1392-401. . Solanto MV, Marks DJ, Wasserstein J, Mitchell K, Abikoff H, Alvir JM, et al. Efficacy of Meta-Cognitive Therapy for Adult ADHD. Am J Psychiatry . 2010 Aug. 167(8):958-968. . Pelham WE Jr, Fabiano GA. Evidence-based psychosocial treatments for attention-deficit/hyperactivity disorder. J Clin Child Adolesc Psychol . 2008 Jan. 37(1):184-214. . Young S, Myanthi Amarasinghe J. Practitioner Review: Non-pharmacological treatments for ADHD: A lifespan approach. J Child

2014 eMedicine.com

117. Attention Deficit Hyperactivity Disorder (Overview)

. June 2017. Available at . FDA. FDA warns of rare risk of long-lasting erections in males taking methylphenidate ADHD medications and has approved label changes. US Food and Drug Administration. Available at . Accessed: January 16, 2014. Webb JR, Valasek MA, North CS. Prevalence of stimulant use in a sample of US medical students. Ann Clin Psychiatry . 2013 Feb. 25(1):27-32. . Lichtenstein P, Halldner L, Zetterqvist J, et al. Medication for attention deficit-hyperactivity disorder and criminality. N (...) of Parent-Reported ADHD Diagnosis and Associated Treatment Among U.S. Children and Adolescents, 2016. J Clin Child Adolesc Psychol . 2018 Mar-Apr. 47 (2):199-212. . Visser SN, Danielson ML, Bitsko RH, Holbrook JR, Kogan MD, Ghandour RM, et al. Trends in the parent-report of health care provider-diagnosed and medicated attention-deficit/hyperactivity disorder: United States, 2003-2011. J Am Acad Child Adolesc Psychiatry . 2014 Jan. 53 (1):34-46.e2. . Akinbami LJ, Liu X, Pastor PN, Reuben CA. Attention

2014 eMedicine.com

118. Attention Deficit Hyperactivity Disorder (Follow-up)

functioning in children with attention-deficit/hyperactivity disorder: Combined type with and without a stimulant medication history. Neuropsychology . 2008 May. 22(3):329-40. . Blader JC, Schooler NR, Jensen PS, Pliszka SR, Kafantaris V. Adjunctive divalproex versus placebo for children with ADHD and aggression refractory to stimulant monotherapy. Am J Psychiatry . 2009 Dec. 166(12):1392-401. . Solanto MV, Marks DJ, Wasserstein J, Mitchell K, Abikoff H, Alvir JM, et al. Efficacy of Meta-Cognitive Therapy (...) Years After Traumatic Brain Injury. . Danielson ML, Bitsko RH, Ghandour RM, Holbrook JR, Kogan MD, Blumberg SJ. Prevalence of Parent-Reported ADHD Diagnosis and Associated Treatment Among U.S. Children and Adolescents, 2016. J Clin Child Adolesc Psychol . 2018 Mar-Apr. 47 (2):199-212. . Visser SN, Danielson ML, Bitsko RH, Holbrook JR, Kogan MD, Ghandour RM, et al. Trends in the parent-report of health care provider-diagnosed and medicated attention-deficit/hyperactivity disorder: United States, 2003

2014 eMedicine.com

119. Attention Deficit Hyperactivity Disorder (Diagnosis)

. June 2017. Available at . FDA. FDA warns of rare risk of long-lasting erections in males taking methylphenidate ADHD medications and has approved label changes. US Food and Drug Administration. Available at . Accessed: January 16, 2014. Webb JR, Valasek MA, North CS. Prevalence of stimulant use in a sample of US medical students. Ann Clin Psychiatry . 2013 Feb. 25(1):27-32. . Lichtenstein P, Halldner L, Zetterqvist J, et al. Medication for attention deficit-hyperactivity disorder and criminality. N (...) of Parent-Reported ADHD Diagnosis and Associated Treatment Among U.S. Children and Adolescents, 2016. J Clin Child Adolesc Psychol . 2018 Mar-Apr. 47 (2):199-212. . Visser SN, Danielson ML, Bitsko RH, Holbrook JR, Kogan MD, Ghandour RM, et al. Trends in the parent-report of health care provider-diagnosed and medicated attention-deficit/hyperactivity disorder: United States, 2003-2011. J Am Acad Child Adolesc Psychiatry . 2014 Jan. 53 (1):34-46.e2. . Akinbami LJ, Liu X, Pastor PN, Reuben CA. Attention

2014 eMedicine.com

120. Attention Deficit Hyperactivity Disorder (Overview)

multiple outcome domains. J Am Acad Child Adolesc Psychiatry . 2014 Aug. 53(8):835-847.e5. . Brauser D. Behavioral interventions effective for ADHD. Medscape Medical News . July 31, 2014. . Spinelli S, Joel S, Nelson TE, Vasa RA, Pekar JJ, Mostofsky SH. Different neural patterns are associated with trials preceding inhibitory errors in children with and without attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry . 2011 Jul. 50(7):705-715.e3. . Ducharme S, Hudziak JJ, Botteron (...) Psychologist, The Affinity Center Christine A Mayhall, PhD is a member of the following medical societies: Disclosure: Nothing to disclose. Mary L Windle, PharmD Adjunct Associate Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference Disclosure: Nothing to disclose. What would you like to print? What would you like to print? Sections Pediatric Attention Deficit Hyperactivity Disorder (ADHD) Find Us On About Membership WebMD Network Editions All

2014 eMedicine Pediatrics

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