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41. Depression: Perinatal

element of BHI has been transitioning primary care social workers to a new role of integrated behavioral health specialist, in which they work as “provider extenders” to address patient needs without disrupting patient flow and team cycle time. Social workers offer consultation to providers, brief interventions, or short-term (4–6 visits) counseling for individuals with mild to moderate depression and alcohol or substance use disorders. Maternal Behavioral Health (MBH) Screening is part of the BHI (...) the first year of the baby’s life. • Women who are already taking antidepressant medications and are considering becoming pregnant. Behavioral Health Integration/Maternal Behavioral Health Kaiser Permanente Washington has integrated behavioral health into all primary care clinics. The goal of Behavioral Health Integration (BHI) is to create a welcoming environment for patients to address common problems—alcohol and substance use disorders as well as depression—with their primary care teams. A major

2020 Kaiser Permanente Clinical Guidelines

42. Treatment of Depression in Children and Adolescents

and harms of pharmacological and nonpharmacological treatments for child and adolescent depressive disorders. Key Messages • Cognitive behavioral therapy (CBT), fluoxetine, escitalopram, and combined fluoxetine plus CBT may reduce depressive symptoms in the short term; clinical significance is unclear. • CBT may improve symptoms and functional status. CBT plus medications may help prevent relapse. • Selective serotonin reuptake inhibitors (SSRIs) as a class may improve response and functional status (...) . • However, SSRIs may be associated with a higher risk of serious adverse events and with a higher risk of withdrawal. Paroxetine may be associated with a higher risk of suicidal ideation or behaviors. Evidence to judge the risk of suicidal ideation or behavior for SSRIs other than paroxetine is insufficient for major depressive disorder. However, this report excluded data on inpatients and those without depressive disorders whom the Food and Drug Administration included in finding an increased risk

2020 Effective Health Care Program (AHRQ)

43. Nonopioid Pharmacologic Treatments for Chronic Pain

events of interest were not reported (cognitive effects, misuse, addiction, substance use disorder).ES-9 Table C. Effects of antidepressants in placebo-controlled and head-to-head trials Condition Drug Pain Short Term Effect Size SOE Pain Intermediate Term Effect Size SOE Function Short Term Effect Size SOE Function Intermediate Term Effect Size SOE QoL Short Term Effect Size SOE QoL Intermediate Term Effect Size SOE Neuropathic pain Duloxetine vs. placebo Moderate ++ No evidence Small + No evidence (...) =019872. Accessed July 31, 2019. 11. Acetaminophen. nophen.html. Accessed July 31, 2019. 12. Kansagara D, O'Neil M, Nugent S, et al. VA Evidence-based Synthesis Program Reports. Benefits and Harms of Cannabis in Chronic Pain or Post-traumatic Stress Disorder: A Systematic Review. Washington, DC: Department of Veterans Affairs (US); 2017. 13. Bannuru RR, Schmid CH, Kent DM, et al. Comparative effectiveness of pharmacologic interventions for knee osteoarthritis

2020 Effective Health Care Program (AHRQ)

44. Seasonal affective disorder

clinical management and monitoring are typically required. Light therapy and/or bupropion (extended release) may be used as prophylactic therapy. Definition All patients must meet the diagnostic criteria for recurrent major depression or bipolar mood disorder. Seasonal affective disorder (SAD) is then a sub-type specifier used to describe temporal variations of these disorders. As such, SAD is not considered a stand-alone diagnosis or comorbid condition to recurrent major depression or bipolar disorder (...) symptoms spring or summer depression manic/hypomanic symptoms somatic symptoms behavioural withdrawal functional impairments excessive alcohol use tachycardia increased systolic blood pressure restlessness exposure to diminished light during winter and increased light during summer residing at a northern latitude family history of SAD female gender age 20 to 30 years psychological factors (e.g., high neuroticism) psychiatric comorbidity (e.g., anxiety, ADHD, premenstrual dysphoric disorders) alcohol

2018 BMJ Best Practice

45. Guidance on the clinical management of anxiety disorders, specifically focusing on diagnosis and treatment strategies

capacity to think, plan and do complex tasks that also need attention in difficult situations. It is normal for a person’s current level of anxiety to affect their ability to perform. However, people with anxiety disorders experience very pronounced states of anxiety, often against a background of constant fear and worry. These severe states of anxiety can be disabling. Anxiety disorders involve unhelpful thinking patterns Having an anxiety disorder is not just a matter of being too anxious. People (...) covered in these guidelines is characterised by specific thoughts and behaviours: • • Panic disorder – sudden attacks of fear or anxiety (usually brief, but which may be so severe that the person thinks they might collapse or die), concern about the attacks recurring and avoidance of situa- tions in which they might recur. • • Social anxiety disorder (SAD) – fear and avoidance of situations where the person thinks they might be the centre of attention, concern about doing or saying something

2018 Royal Australian and New Zealand College of Psychiatrists

46. Buspirone

with buspirone versus atomoxetine monotherapy and placebo (...) in adult attention-deficit/hyperactivity disorder (ADHD). In this randomized, 8-week, 3-arm, double-blind, placebo-controlled trial conducted from November 2004 through December 2005, 241 adults with ADHD were randomly assigned in a 2:2:1 ratio to receive up to twice-daily atomoxetine and thrice-daily buspirone (n = 97), twice-daily atomoxetine (n = 97), or placebo (n = 47). Participants met the Diagnostic and Statistical Manual of Mental (...) Disorders, Fourth Edition, Text Revision criteria for ADHD. The 2012 10. Effects of Buspirone on Agitation Associated With Dementia. Ten patients with probable Alzheimer's disease participated in an open-label study of buspirone for agitation. The starting dose of 15 mg/day was increased by 5 mg every week until maximal improvement or 60 mg/day was reached. A significant decrease in agitation scores occurred at an average dose of 35 mg/day. Copyright © 1993 American Association for Geriatric Psychiatry

2018 Trip Latest and Greatest

47. Amphetamine

of this page. But if you still have questions please contact us via Top results for amphetamine 1. Amphetamines for attention deficit hyperactivity disorder (ADHD) in adults. BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is a childhood-onset disorder characterised by inattention, hyperactivity, and impulsivity. ADHD can persist into adulthood and can affects individuals' social and occupational functioning, as well as their quality of life and health. ADHD (...) hospitals forming two groups of participants. The patients reported amphetamine use at least once in the past month prior to the present study 2012 5. Amphetamines and methylphenidate for paediatric ADHD: meta-analysis of n-of-1 trials Amphetamines and methylphenidate for paediatric ADHD Search National Elf Service Search National Elf Service » » » » Amphetamines and methylphenidate for paediatric ADHD: meta-analysis of n-of-1 trials May 24 2016 Posted by Attention-Deficit/Hyperactivity Disorder (ADHD

2018 Trip Latest and Greatest

48. ESC/ESH Management of Arterial Hypertension Full Text available with Trip Pro

in women) Autoimmune and other inflammatory disorders Major psychiatric disorders Treatment for infection with human immunodeficiency virus Atrial fibrillation LV hypertrophy CKD Obstructive sleep apnoea syndrome Social deprivation, the origin of many causes of CVD Obesity (measured by BMI) and central obesity (measured by waist circumference) Physical inactivity Psychosocial stress, including vital exhaustion Family history of premature CVD (occurring at age <55 years in men and <60 years in women (...) ) Autoimmune and other inflammatory disorders Major psychiatric disorders Treatment for infection with human immunodeficiency virus Atrial fibrillation LV hypertrophy CKD Obstructive sleep apnoea syndrome BMI = body mass index; CKD = chronic kidney disease; CVD = cardiovascular disease; LV = left ventricular. Table 6 Risk modifiers increasing cardiovascular risk estimated by the Systemic COronary Risk Evaluation (SCORE) system Social deprivation, the origin of many causes of CVD Obesity (measured by BMI

2018 European Society of Cardiology

49. CPIC Guideline for Atomoxetine based on CYP2D6 genotype

is associated with clinical response to atomoxetine in attention- deficit hyperactivity disorder (ADHD). Neuropsychopharmacology 34, 2135–2142 (2009). 3 2. T o d o r , I. et al. Evaluation of a potential metabolism- mediated drug- drug interaction between atomoxetine and bupropion in healthy volunteers. J. Pharm. Pharm. Sci. 19, 198–207 (2016). 33. Paulzen, M., Clement, H.W. & Grunder, G. Enhancement of ato- moxetine serum levels by co- administration of paroxetine. Int. J. Neuropsychopharmacol. 11, 289–291 (...) . Steven Leeder 7,8,* Atomoxetine is a nonstimulant medication used to treat attention- deficit/hyperactivity disorder (ADHD). Cytochrome P450 (CYP)2D6 polymorphisms influence the metabolism of atomoxetine thereby affecting drug efficacy and safety. We summarize evidence from the published literature supporting these associations and provide therapeutic recommendations for atomoxetine based on CYP2D6 genotype (updates at www. The purpose of this guideline is to provide information

2019 Clinical Pharmacogenetics Implementation Consortium

50. Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder

.2012.07.008. PMID: 22921765. 32. Ivarsson D, Blom M, Hesser H, et al. Guided internet-delivered cognitive behavior therapy for post-traumatic stress disorder: a randomized controlled trial. Internet Interv. 2014 March;1(1):33-40. doi: 10.1016/j.invent.2014.03.002. 33. Kangas M, Milross C, Taylor A, et al. A pilot randomized controlled trial of a brief early intervention for reducing posttraumatic stress disorder, anxiety and depressive symptoms in newly diagnosed head and neck cancer patients (...) , Hertzberg MA, Moore SD, et al. A placebo-controlled trial of bupropion SR in the treatment of chronic posttraumatic stress disorder. J Clin Psychopharmacol. 2007 Apr;27(2):193-7. doi: 10.1097/JCP.0b013e318032eaed. PMID: 17414245. 49. Brady K, Pearlstein T, Asnis GM, et al. Efficacy and safety of sertraline treatment of posttraumatic stress disorder: a randomized controlled trial. JAMA. 2000 Apr;283(14):1837-44. doi: 10.1001/jama.283.14.1837. PMID: 10770145. 50. Brady KT, Sonne SC, Anton RF, et al

2019 Effective Health Care Program (AHRQ)

51. Heart Disease and Stroke Statistics Full Text available with Trip Pro

, Andrew Stokes , David L. Tirschwell , Connie W. Tsao , Mintu P. Turakhia , Lisa B. VanWagner , John T. Wilkins , Sally S. Wong , Salim S. Virani , Originally published 31 Jan 2019 Circulation. 2019;139:e56–e66 Each chapter listed in the Table of Contents (see next page) is a hyperlink to that chapter. The reader clicks the chapter name to access that chapter. Table of Contents Summary e57 1. About These Statistics e67 2. Cardiovascular Health e70 Health Behaviors 3. Smoking/Tobacco Use e87 4 (...) . Physical Inactivity e99 5. Nutrition e119 6. Overweight and Obesity e138 Health Factors and Other Risk Factors 7. High Blood Cholesterol and Other Lipids e161 8. High Blood Pressure e174 9. Diabetes Mellitus e193 10. Metabolic Syndrome e212 11. Kidney Disease e233 12. Sleep e249 Cardiovascular Conditions/Diseases 13. Total Cardiovascular Diseases e257 14. Stroke (Cerebrovascular Disease) e281 15. Congenital Cardiovascular Defects and Kawasaki Disease e327 16. Disorders of Heart Rhythm e346 17. Sudden

2019 American Heart Association

52. Clinical Practice Guidelines for the Perioperative Nutrition, Metabolic, and Nonsurgical Support of Patients Undergoing Bariatric Procedures

). Follow-up data from the National Institutes of Health (NIH)-supported, prospective cohort Longitudinal Assessment of Bariatric Surgery (LABS) continue to inform clinical care regarding various aspects of postoperative management, including weight-loss trajectories (50), behavioral variables, DOI:10.4158/GL-2019-0406 © 2019 AACE. 20 3-year weight changes (51), and risks for developing alcohol-use disorder (52). Lastly, postoperative weight regain is recognized as a significant clinical issue (...) , psychiatry, psychiatric nursing, etc., with specialized knowledge and training relevant to obesity, eating disorders, and/or bariatric procedures), which assesses environmental, familial, and behavioral factors, as well as risk for suicide, should be required for all patients before a bariatric procedure (Grade C; BEL 3). Any patient considered for a bariatric procedure with a known or suspected psychiatric illness, or substance abuse or dependence, should undergo a formal mental health evaluation before

2019 American Association of Clinical Endocrinologists

53. Clinical Practice Guideline for the Treatment of Depression Across Three Age Cohorts

to Appendix A of the supplement. APA GUIDELINE FOR THE TREATMENT OF DEPRESSION ES-10 Table 1 Recommendations for the Child Population from the APA Guideline Development Panel for the Treatment of Depression 8 Recommendation Strength of Recommendation Justification Initial Treatment For initial treatment of child patients with depressive disorders 9 there was insufficient evidence to make a recommendation regarding any of the following psychotherapies/interventions 10 : • Behavioral therapy • Cognitive (...) therapy • Cognitive-behavioral therapy (CBT) • Family therapy • Play therapy • Problem-solving therapy • Psychodynamic therapy • Supportive therapy There was insufficient evidence to make a recommendation regarding pharmacotherapy for child patients with depressive disorders. Insufficient evidence for a recommendation Based on the literature reviewed that met the AMSTAR requirements, there was insufficient evidence to either recommend or not recommend use of the listed psychotherapies/interventions

2019 American Psychological Association

55. Guideline for concussion/mild traumatic brain injury & persistent symptoms - Mental Health Disorders

resulting from the injury. People with persistent symptoms may become isolated from others as they may be intolerant of or unable to engage in social interactions. Their injury status may disrupt their occupational status, leisure activities and interpersonal interactions. They may also incur losses (e.g., reduced quality of life and independence; lowered income or reduced educational attainment; changes in relationship functioning, etc.). When assessing and managing disorders of mental health post mTBI (...) severe mental health symptoms such as Major Depressive Disorder (MDD) and Post- Traumatic Stress Disorder (PTSD). 4 Depressive disorders following TBI are commonly associated with increased irritability and often comorbid with anxiety symptoms as well as with fatigue, sleep disturbances, cognitive dysfunction, decreased mobility, emotional processing deficits and anxiety syndromes. The latter include generalized anxiety, panic attacks, phobic disorders, and post-traumatic stress disorder (PTSD

2018 Ontario Neurotrauma Foundation

56. QTc Prolongation and Psychotropic Medications

about electrolyte monitoring will facilitate the process and minimize duplication. Acute medical conditions (e.g., gastroenteritis, endocrinopathies), physiological conditions (e.g., gravida emesis, strenuous exercise), or fasting can also cause electrolyte disruption. Furthermore, certain diagnoses can be accompanied by behaviors (e.g., purging and/or dietary restriction in eating disorders, binge drinking in alcohol use disorder, use of © Copyright, American Psychiatric Association, all rights (...) General Hospital, Boston, MA; 3 Harvard Medical School, Boston, MA; 4 Department of Clinical Pharmacy, University of Michigan College of Pharmacy, Ann Arbor, MI; 5 Mount Pearl, Newfoundland, Canada; 6 Department of Psychiatry, Virginia Commonwealth University, Richmond, VA; 7 Department of Psychiatry and Behavioral Sciences, Northwestern Feinberg School of Medicine, Chicago, IL; 8 Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI; 9 Krannert Institute of Cardiology

2018 American Psychiatric Association

57. Guidelines for the Evaluation and Treatment of Perimenopausal Depression

, 10 Claudio N. Soares, MD, PhD, MBA, 11 on behalf of the Board of Trustees for The North American Menopause Society (NAMS) and the Women and Mood Disorders Task Force of the National Network of Depression Centers Abstract There is a new appreciation of the perimenopause – defined as the early and late menopause transition stages as well as the early postmenopause - as a window of vulnerability for the development of both depressive symptoms and major depressive episodes. However, clinical (...) the National Pregnancy Registry for Atypical Antipsychotics, Alkermes Biopharmaceuticals, Forest/Actavis Pharmaceuticals, Otsuka Pharma- ceuticals, Sunovion Pharmaceuticals, Inc, Teva Pharmaceuticals, the Brain & Behavior Research Foundation, JayMac Pharmaceuticals, SAGE Therapeutics, and Takeda/Lundbeck Pharmaceuticals, as well as consul- tant fees from Alkermes Biopharmaceuticals. Dr. Soares has received honoraria as a consultant for Bayer, Lundbeck, Otsuka and Pfizer. He has also received grants from

2018 The North American Menopause Society

58. Treatment for Bipolar Disorder in Adults: A Systematic Review

episodes, some aim to reduce acute depression symptoms, and others aim to reduce acute symptoms, maintain relatively symptom-free periods, and prevent relapsing to acute episodes. Given the chronic, relapsing/remitting course of bipolar disorder and the need for maintenance treatment in many patients, drugs begun for an acute mood episode (including mania) are often carried forward into maintenance therapy. Nondrug psychosocial therapeutic approaches range from psychoeducational, cognitive behavioral (...) Treatment for Bipolar Disorder in Adults: A Systematic Review Comparative Effectiveness Review Number 208 Treatment for Bipolar Disorder in Adults: A Systematic Review eComparative Effectiveness Review Number 208 Treatment for Bipolar Disorder in Adults: A Systematic Review Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 5600 Fishers Lane Rockville, MD 20857 Contract No. 290-2012-00016-I Prepared by: Minnesota Evidence-based

2018 Effective Health Care Program (AHRQ)

59. Depression: Adult and Adolescent

health and substance use concerns by integrating behavioral health into primary care clinics. The goal of BHI is to create a welcoming environment for patients to address common problems— alcohol and substance use disorders as well as depression— with their primary care teams. A major element of BHI is transitioning primary care social workers to a new role—that of integrated behavioral health specialist—in which they will work as provider extenders to address patient needs without disrupting patient (...) , other mental health conditions, and life stressors to consider in ADOLESCENTS Mental health condition or life stressor Additional depression questions (ADQs) (on back of PHQ-9A) 1 Next steps ADHD ADQ #12: Are you having difficulty with school work? If yes, consider assessing for ADHD. Anxiety disorders, including generalized anxiety disorder, obsessive-compulsive disorder, and panic disorder GAD-2 ADQ #20: Over the last 2 weeks, how often have you been bothered by the following problems? • Feeling

2017 Kaiser Permanente Clinical Guidelines

60. Management of Acute Myocardial Infarction in patients presenting with ST-segment elevation Full Text available with Trip Pro

be taken strongly into consideration to argue against an invasive coronary strategy. Unconscious patients admitted to critical care units after out-of-hospital cardiac arrest are at high risk for death, and neurologic deficits are common among those who survive. Targeted temperature management (also called therapeutic hypothermia), aiming for a constant temperature between 32 and 36 °C for at least 24 h, is indicated in patients who remain unconscious after resuscitation from cardiac arrest (...) (of presumed cardiac cause). , However, hypothermia conditions are associated with slow uptake, delayed onset of action, and diminished effects of oral antiplatelet agents (i.e. clopidogrel, ticagrelor, and prasugrel). Moreover, metabolic conversion of clopidogrel in the liver may be reduced in hypothermia conditions. Cooling should not delay primary PCI and can be started in parallel in the catheterization laboratory. Close attention to anticoagulation needs to be paid in patients reaching low

2017 European Society of Cardiology

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